{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T05:49:21Z","timestamp":1790660961988,"version":"4.1.0"},"reference-count":72,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T00:00:00Z","timestamp":1784764800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","thegreenjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Radiotherapy and Oncology"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.radonc.2026.111707","type":"journal-article","created":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T23:12:01Z","timestamp":1784329921000},"page":"111707","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["ESTRO clinical practice guideline on high-dose thoracic reirradiation for non-small cell lung cancer"],"prefix":"10.1016","volume":"222","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3647-5916","authenticated-orcid":false,"given":"Nicolaus","family":"Andratschke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2531-3551","authenticated-orcid":false,"given":"Jonas","family":"Willmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1775-2009","authenticated-orcid":false,"given":"Edy","family":"Ippolito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Greco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Rulach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0741-994X","authenticated-orcid":false,"given":"Eliana Vasquez","family":"Osorio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Rimner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2935-1843","authenticated-orcid":false,"given":"Cecile Le","family":"Pechoux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose","family":"Belderbos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2594-1486","authenticated-orcid":false,"given":"Max","family":"Dahele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7146-9071","authenticated-orcid":false,"given":"Matthias","family":"Guckenberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1003-5138","authenticated-orcid":false,"given":"Gerard","family":"Hanna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul Van","family":"Houtte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9157-3730","authenticated-orcid":false,"given":"Yolande","family":"Lievens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ursula","family":"Nestle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Palma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9224-9318","authenticated-orcid":false,"given":"Christoph","family":"P\u00f6ttgen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5782-7717","authenticated-orcid":false,"given":"Sara","family":"Ramella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Salem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-7730-7881","authenticated-orcid":false,"given":"Helen","family":"Grimes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6705-1561","authenticated-orcid":false,"given":"Tina","family":"Schytte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joost J","family":"Nuyttens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Harrow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0867-3694","authenticated-orcid":false,"suffix":"II","given":"Charles B.","family":"Simone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4406-7621","authenticated-orcid":false,"given":"Umberto","family":"Ricardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.radonc.2026.111707_b0205","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1038\/s41571-023-00798-3","article-title":"The global burden of lung cancer: current status and future trends","volume":"20","author":"Leiter","year":"2023","journal-title":"Nat Rev Clin Oncol"},{"key":"10.1016\/j.radonc.2026.111707_b0065","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1016\/S1470-2045(21)00401-0","article-title":"Stereotactic ablative radiotherapy for operable stage i non-small-cell lung cancer (revised STARS): long-term results of a single-arm, prospective trial with prespecified comparison to surgery","volume":"22","author":"Chang","year":"2021","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.radonc.2026.111707_b0315","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1200\/JCO.21.01308","article-title":"Five-year survival outcomes from the PACIFIC trial: durvalumab after chemoradiotherapy in stage iii non-small-cell lung cancer","volume":"40","author":"Spigel","year":"2022","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.radonc.2026.111707_b0330","doi-asserted-by":"crossref","unstructured":"Tsai, Chiaojung Jillian, Jonathan T. Yang, Narek Shaverdian, et al. 2023. \u201cStandard-of-Care Systemic Therapy with or without Stereotactic Body Radiotherapy in Patients with Oligoprogressive Breast Cancer or Non-Small-Cell Lung Cancer (Consolidative Use of Radiotherapy to Block [CURB] Oligoprogression): An Open-Label, Randomised, Controlled, Phase 2 Study.\u201d The Lancet, ahead of print, December 14. Doi: 10.1016\/S0140-6736(23)01857-3.","DOI":"10.1016\/S0140-6736(23)01857-3"},{"key":"10.1016\/j.radonc.2026.111707_b0140","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1200\/JCO.19.00201","article-title":"Local consolidative therapy vs. maintenance therapy or observation for patients with oligometastatic non-small-cell lung cancer: long-term results of a multi-institutional, phase ii, randomized study","volume":"37","author":"Gomez","year":"2019","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.radonc.2026.111707_b0170","doi-asserted-by":"crossref","DOI":"10.1001\/jamaoncol.2017.3501","article-title":"Consolidative radiotherapy for limited metastatic non-small-cell lung cancer: a phase 2 randomized clinical trial","volume":"4","author":"Iyengar","year":"2018","journal-title":"JAMA Oncol"},{"key":"10.1016\/j.radonc.2026.111707_b0035","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1016\/S1470-2045(18)30896-9","article-title":"Stereotactic ablative radiotherapy versus standard radiotherapy in stage 1 non-small-cell lung cancer (TROG 09.02 CHISEL): a phase 3, open-label, randomised controlled trial","volume":"20","author":"Ball","year":"2019","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.radonc.2026.111707_b0325","first-page":"31","article-title":"Stereotactic body radiation therapy for operable early-stage lung cancer","volume":"9183","author":"Timmerman","year":"2018","journal-title":"JAMA Oncol"},{"key":"10.1016\/j.radonc.2026.111707_b0025","doi-asserted-by":"crossref","first-page":"2181","DOI":"10.1200\/JCO.2009.26.2543","article-title":"Meta-analysis of concomitant versus sequential radiochemotherapy in locally advanced non - small-cell lung cancer","volume":"28","author":"Aup\u00e9rin","year":"2010","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.radonc.2026.111707_b0115","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1016\/j.ijrobp.2023.10.005","article-title":"Patterns of failure, low-volume relapse, and subsequent ablative management in locally advanced non-small cell lung cancer treated with definitive chemoradiation and consolidation immune checkpoint inhibitors","volume":"118","author":"Friedes","year":"2024","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2026.111707_b0125","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.cllc.2023.09.002","article-title":"Patterns of failure in metastatic NSCLC treated with first line pembrolizumab and use of local therapy in patients with oligoprogression","volume":"25","author":"Friedes","year":"2024","journal-title":"Clin Lung Cancer"},{"key":"10.1016\/j.radonc.2026.111707_b0355","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.ijrobp.2023.08.047","article-title":"Phase 2 trial of consolidation pembrolizumab after proton reirradiation for thoracic recurrences of non-small cell lung cancer","volume":"119","author":"Yegya-Raman","year":"2024","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2026.111707_b0120","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.ijrobp.2025.09.016","article-title":"Primary tumor failure after definitive chemoradiation in locally advanced non-small cell lung cancer: a brief report on the implications for NRG LU-008","volume":"124","author":"Friedes","year":"2026","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2026.111707_b0010","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1097\/JTO.0000000000000648","article-title":"Pattern of failure analysis in metastatic EGFR-mutant lung cancer treated with tyrosine kinase inhibitors to identify candidates for consolidation stereotactic body radiation therapy","volume":"10","author":"Al-Halabi","year":"2015","journal-title":"J Thorac Oncol"},{"key":"10.1016\/j.radonc.2026.111707_b0340","doi-asserted-by":"crossref","DOI":"10.1016\/j.radonc.2023.109947","article-title":"Re-Irradiation in clinical practice: results of an international patterns of care survey within the framework of the ESTRO-EORTC E2-RADIatE platform","volume":"189","author":"Willmann","year":"2023","journal-title":"Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology"},{"key":"10.1016\/j.radonc.2026.111707_b0085","doi-asserted-by":"crossref","first-page":"e620","DOI":"10.1016\/S1470-2045(14)70345-6","article-title":"High-dose re-irradiation following radical radiotherapy for non-small-cell lung cancer","volume":"15","author":"Ruysscher","year":"2014","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.radonc.2026.111707_b0045","article-title":"Reirradiation: standards, challenges, and patient-focused strategies across tumor types","author":"Beddok","year":"2025","journal-title":"CA Cancer J Clin"},{"key":"10.1016\/j.radonc.2026.111707_b0070","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.jtho.2016.10.018","article-title":"Multi-institutional prospective study of reirradiation with proton beam radiotherapy for locoregionally recurrent non-small cell lung cancer","volume":"12","author":"Chao","year":"2017","journal-title":"J Thorac Oncol"},{"key":"10.1016\/j.radonc.2026.111707_b0260","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.radonc.2011.09.012","article-title":"Toxicity after reirradiation of pulmonary tumours with stereotactic body radiotherapy","volume":"101","author":"Peulen","year":"2011","journal-title":"Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology"},{"key":"10.1016\/j.radonc.2026.111707_b0250","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1007\/s00066-023-02118-1","article-title":"Prospective randomized clinical studies involving reirradiation: update of a systematic review","volume":"199","author":"Nieder","year":"2023","journal-title":"Strahlentherapie Und Onkologie: Organ Der Deutschen Rontgengesellschaft [et Al]"},{"key":"10.1016\/j.radonc.2026.111707_b0345","doi-asserted-by":"crossref","DOI":"10.1016\/j.radonc.2024.110624","article-title":"Ongoing prospective studies on reirradiation: a systematic review of a clinical trials database","volume":"202","author":"Willmann","year":"2025","journal-title":"Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology"},{"key":"10.1016\/j.radonc.2026.111707_b0275","article-title":"An international expert survey on the indications and practice of radical thoracic reirradiation for non-small cell lung cancer","volume":"6","author":"Rulach","year":"2021","journal-title":"Adv Radiat Oncol"},{"key":"10.1016\/j.radonc.2026.111707_b0305","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijrobp.2025.03.056","article-title":"American radium society appropriate use criteria systematic review and guidelines on reirradiation for non-small cell lung cancer executive summary","author":"Simone","year":"2025","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2026.111707_b0310","doi-asserted-by":"crossref","first-page":"8003","DOI":"10.1200\/JCO.2025.43.16_suppl.8003","article-title":"SWOG\/NRG S1914: randomized phase iii trial of induction\/consolidation atezolizumab + SBRT versus SBRT alone in high risk, early-stage NSCLC","volume":"43","author":"Simone","year":"2025","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.radonc.2026.111707_b0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.radonc.2025.111313","article-title":"Cumulative dose evaluation in clinical reirradiation - consensus guidance on technical considerations by the ESTRO reirradiation focus group","volume":"214","author":"Appelt","year":"2026","journal-title":"Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology"},{"key":"10.1016\/j.radonc.2026.111707_b0015","doi-asserted-by":"crossref","first-page":"e469","DOI":"10.1016\/S1470-2045(22)00447-8","article-title":"European society for radiotherapy and oncology and european organisation for research and treatment of cancer consensus on re-irradiation: definition, reporting, and clinical decision making","volume":"23","author":"Andratschke","year":"2022","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.radonc.2026.111707_b0255","doi-asserted-by":"crossref","first-page":"e101","DOI":"10.1016\/S1470-2045(25)00562-5","article-title":"Reirradiation collaborative group (ReCOG) consensus on standards for dose evaluation and reporting in patients with multiple courses of radiation therapy: an AAPM\/ACRO\/ASTRO\/CARO\/COMP\/CADRA\/CPQR\/ESTRO\/NRG-endorsed consensus statement","volume":"27","author":"Paradis","year":"2026","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.radonc.2026.111707_b0030","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.prro.2019.02.008","article-title":"Clinical outcomes of patients with recurrent lung cancer reirradiated with proton therapy on the proton collaborative group and university of florida proton therapy institute prospective registry studies","volume":"9","author":"Badiyan","year":"2019","journal-title":"Pract Radiat Oncol"},{"key":"10.1016\/j.radonc.2026.111707_b0270","doi-asserted-by":"crossref","unstructured":"Rocchetti, Jenna, Nikhil Yegya-Raman, Michelle Iocolano, et al. 2025. \u201cSalvage Thoracic Reirradiation for Recurrent Non-Small Cell Lung Cancer: Clinical Efficacy and the Impact of Consolidative Immunotherapy.\u201d Doi: 10.2139\/ssrn.5165504.","DOI":"10.2139\/ssrn.5165504"},{"key":"10.1016\/j.radonc.2026.111707_b0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.radonc.2025.111003","article-title":"Evaluation of the prognostic value of the ESTRO\/EORTC classification of reirradiation in patients with non-small cell lung cancer","volume":"210","author":"D\u00e4hler","year":"2025","journal-title":"Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology"},{"key":"10.1016\/j.radonc.2026.111707_b0060","article-title":"High-dose reirradiation for in-field recurrent lung cancer in the THOrax (RETHO): outcomes of a phase 2 prospective clinical trial","author":"Cammareri","year":"2025","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2026.111707_b0165","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.prro.2023.04.004","article-title":"Treatment of oligometastatic non-small cell lung cancer: an ASTRO\/ESTRO clinical practice guideline","volume":"13","author":"Iyengar","year":"2023","journal-title":"Pract Radiat Oncol"},{"key":"10.1016\/j.radonc.2026.111707_b0320","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.radonc.2021.04.014","article-title":"Outcomes of curative-intent radiotherapy in non-small cell lung cancer (NSCLC) patients with chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD)","volume":"160","author":"Tang","year":"2021","journal-title":"Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology"},{"key":"10.1016\/j.radonc.2026.111707_b0290","doi-asserted-by":"crossref","first-page":"e493","DOI":"10.1016\/j.clon.2022.01.043","article-title":"\u201cIs thoracic radiotherapy an absolute contraindication for treatment of lung cancer patients with interstitial lung disease?","volume":"34","author":"Saha","year":"2022","journal-title":"A Systematic Review\u201d Clinical Oncology (Royal College of Radiologists (Great Britain))"},{"key":"10.1016\/j.radonc.2026.111707_b0095","first-page":"75","article-title":"Thoracic reirradiation for lung cancer: a literature review and practical guide","volume":"3","author":"Drodge","year":"2014","journal-title":"Annals of Palliative Medicine"},{"key":"10.1016\/j.radonc.2026.111707_b0210","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1016\/j.ijrobp.2012.02.020","article-title":"Predicting radiation pneumonitis after stereotactic ablative radiation therapy in patients previously treated with conventional thoracic radiation therapy","volume":"84","author":"Liu","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2026.111707_b0350","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1016\/S0360-3016(03)00768-5","article-title":"Three-dimensional conformal radiotherapy for locoregionally recurrent lung carcinoma after external beam irradiation: a prospective phase i-ii clinical trial","volume":"57","author":"Wu","year":"2003","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2026.111707_b0145","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.lungcan.2013.12.006","article-title":"High-dose, conventionally fractionated thoracic reirradiation for lung tumors","volume":"83","author":"Griffioen","year":"2014","journal-title":"Lung Cancer (Amsterdam, Netherlands)"},{"key":"10.1016\/j.radonc.2026.111707_b0265","doi-asserted-by":"crossref","DOI":"10.1186\/s13014-018-1016-z","article-title":"The risk and predictors for severe radiation pneumonitis in lung cancer patients treated with thoracic reirradiation","volume":"13","author":"Ren","year":"2018","journal-title":"Radiation Oncology (London, England)"},{"key":"10.1016\/j.radonc.2026.111707_b0100","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.radonc.2013.02.002","article-title":"Aortic dose constraints when reirradiating thoracic tumors","volume":"106","author":"Evans","year":"2013","journal-title":"Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology"},{"key":"10.1016\/j.radonc.2026.111707_b0235","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.radonc.2013.03.015","article-title":"Reirradiation and stereotactic radiotherapy for tumors in the lung: dose summation and toxicity","volume":"107","author":"Meijneke","year":"2013","journal-title":"Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology"},{"key":"10.1016\/j.radonc.2026.111707_b0225","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/j.ijrobp.2014.07.030","article-title":"Definitive reirradiation for locoregionally recurrent non-small cell lung cancer with proton beam therapy or intensity modulated radiation therapy: predictors of high-grade toxicity and survival outcomes","volume":"90","author":"McAvoy","year":"2014","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2026.111707_b0050","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1016\/j.ijrobp.2015.12.007","article-title":"Dosimetric factors and toxicity in highly conformal thoracic reirradiation","volume":"94","author":"Binkley","year":"2016","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2026.111707_b0360","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1016\/j.annonc.2025.08.003","article-title":"Early and locally advanced non-small-cell lung cancer: ESMO clinical practice guideline for diagnosis, treatment and follow-up","volume":"36","author":"Zer","year":"2025","journal-title":"Ann Oncol"},{"key":"10.1016\/j.radonc.2026.111707_b0160","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.radonc.2011.12.018","article-title":"Radiographic changes after lung stereotactic ablative radiotherapy (SABR)\u2013can we distinguish recurrence from fibrosis? a systematic review of the literature","volume":"102","author":"Huang","year":"2012","journal-title":"Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology"},{"key":"10.1016\/j.radonc.2026.111707_b0110","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/s00259-025-07400-1","article-title":"The utility of [18F]FDG PET in discriminating between local recurrence and inflammatory changes following SABR in primary lung cancer patients","volume":"53","author":"Fala","year":"2025","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1016\/j.radonc.2026.111707_b0295","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.radonc.2020.07.033","article-title":"Re-Irradiation in the thorax - an analysis of efficacy and safety based on accumulated EQD2 doses","volume":"152","author":"Schr\u00f6der","year":"2020","journal-title":"Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology"},{"key":"10.1016\/j.radonc.2026.111707_b0185","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.radonc.2015.03.014","article-title":"PET\/CT imaging for target volume delineation in curative intent radiotherapy of non-small cell lung cancer: IAEA consensus report 2014","volume":"116","author":"Konert","year":"2015","journal-title":"Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology"},{"key":"10.1016\/j.radonc.2026.111707_b0245","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.radonc.2018.02.023","article-title":"ESTRO ACROP guidelines for target volume definition in the treatment of locally advanced non-small cell lung cancer","volume":"127","author":"Nestle","year":"2018","journal-title":"Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology"},{"key":"10.1016\/j.radonc.2026.111707_b0105","doi-asserted-by":"crossref","unstructured":"Expert Panel on Thoracic Imaging:, Patricia M. de Groot, Jonathan H. Chung, et al. 2019. \u201cACR Appropriateness Criteria Noninvasive Clinical Staging of Primary Lung Cancer.\u201d Journal of the American College of Radiology : JACR 16 (5S): S184\u2013S195.","DOI":"10.1016\/j.jacr.2019.02.008"},{"key":"10.1016\/j.radonc.2026.111707_b0220","doi-asserted-by":"crossref","DOI":"10.1016\/j.ctro.2025.101042","article-title":"Thoracic reirradiation clinical and technical practices: a survey from the reirradiation collaborative group (ReCOG)","volume":"56","author":"Matuszak","year":"2026","journal-title":"Clinical and Translational Radiation Oncology"},{"key":"10.1016\/j.radonc.2026.111707_b0300","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.radonc.2013.01.004","article-title":"Outcomes of stereotactic ablative radiotherapy for central lung tumours: a systematic review","volume":"106","author":"Senthi","year":"2013","journal-title":"Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology"},{"key":"10.1016\/j.radonc.2026.111707_b0200","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.ijrobp.2019.03.045","article-title":"Local control after stereotactic body radiation therapy for stage i non-small cell lung cancer","volume":"110","author":"Lee","year":"2021","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2026.111707_b0135","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/j.ijrobp.2024.03.050","article-title":"Stereotactic radiation for ultra-central non-small cell lung cancer: a safety and efficacy trial (SUNSET)","volume":"120","author":"Giuliani","year":"2024","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2026.111707_b0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.radonc.2025.111130","article-title":"Efficacy and safety of twice-daily accelerated hyperfractionated re-irradiation for thoracic malignancies","volume":"212","author":"Doss","year":"2025","journal-title":"Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology"},{"key":"10.1016\/j.radonc.2026.111707_b0280","doi-asserted-by":"crossref","DOI":"10.1016\/j.ctro.2025.101036","article-title":"Re-irradiation of recurrent lung tumours: associations between dose and 2-year survival","volume":"55","author":"Rulach","year":"2025","journal-title":"Clinical and Translational Radiation Oncology"},{"key":"10.1016\/j.radonc.2026.111707_b0130","doi-asserted-by":"crossref","DOI":"10.1002\/acm2.13641","article-title":"AAPM MEDICAL PHYSICS PRACTICE GUIDELINE 5.b: commissioning and QA of treatment planning dose calculations-megavoltage photon and electron beams","volume":"23","author":"Geurts","year":"2022","journal-title":"J Appl Clin Med Phys"},{"key":"10.1016\/j.radonc.2026.111707_b0180","doi-asserted-by":"crossref","first-page":"946","DOI":"10.2340\/1651-226X.2025.43567","article-title":"Clinical workflow for reirradiation: national consensus recommendations on imaging, treatment planning, dose accumulation, and treatment delivery","volume":"64","author":"Kaplan","year":"2025","journal-title":"Acta Oncologica (Stockholm, Sweden)"},{"key":"10.1016\/j.radonc.2026.111707_b0335","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.radonc.2017.08.005","article-title":"Systematic assessment of clinical outcomes and toxicities of proton radiotherapy for reirradiation","volume":"125","author":"Verma","year":"2017","journal-title":"Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology"},{"key":"10.1016\/j.radonc.2026.111707_b0190","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1016\/j.ijrobp.2010.07.1977","article-title":"Consideration of dose limits for organs at risk of thoracic radiotherapy: atlas for lung, proximal bronchial tree, esophagus, spinal cord, ribs, and brachial plexus","volume":"81","author":"Kong","year":"2011","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2026.111707_b0240","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.radonc.2020.06.015","article-title":"Delineation of whole heart and substructures in thoracic radiation therapy: national guidelines and contouring atlas by the danish multidisciplinary cancer groups","volume":"150","author":"Milo","year":"2020","journal-title":"Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology"},{"key":"10.1016\/j.radonc.2026.111707_b0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.radonc.2024.110184","article-title":"Multi-centre evaluation of variation in cumulative dose assessment in reirradiation scenarios","volume":"194","author":"Hardcastle","year":"2024","journal-title":"Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology"},{"key":"10.1016\/j.radonc.2026.111707_b0285","doi-asserted-by":"crossref","DOI":"10.1016\/j.ctro.2026.101108","article-title":"Cumulative oesophageal dose and risk of high-grade toxicity in thoracic re-irradiation: a dose\/toxicity analysis","volume":"57","author":"Rulach","year":"2026","journal-title":"Clinical and Translational Radiation Oncology"},{"key":"10.1016\/j.radonc.2026.111707_b0055","doi-asserted-by":"crossref","first-page":"3610","DOI":"10.1200\/JCO-25-00036","article-title":"Simultaneous durvalumab and platinum-based chemoradiotherapy in unresectable stage iii non-small cell lung cancer: the phase iii PACIFIC-2 study","volume":"43","author":"Bradley","year":"2025","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.radonc.2026.111707_b0075","doi-asserted-by":"crossref","unstructured":"Cortiula, Francesco, Talia Shentzer Kutiel, Melinda L. Hsu, et al. 2025. \u201cComparative Efficacy of Immunotherapy-Based Treatment versus Chemotherapy-Only in Patients with Unresectable NSCLC with Disease Progression Post Chemoradiation and Durvalumab.\u201d European Journal of Cancer (Oxford, England: 1990) 219 (115302): 115302.","DOI":"10.1016\/j.ejca.2025.115302"},{"key":"10.1016\/j.radonc.2026.111707_b0195","doi-asserted-by":"crossref","first-page":"e121","DOI":"10.1016\/S1470-2045(22)00752-5","article-title":"Metastases-directed stereotactic body radiotherapy in combination with targeted therapy or immunotherapy: systematic review and consensus recommendations by the EORTC-ESTRO oligocare consortium","volume":"24","author":"Kroeze","year":"2023","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.radonc.2026.111707_b0005","article-title":"ESMO-ESTRO framework for assessing the interactions and safety of combining radiotherapy with targeted cancer therapies or immunotherapy","volume":"208","author":"Aken","year":"2025","journal-title":"Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology"},{"key":"10.1016\/j.radonc.2026.111707_b0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtocrr.2023.100559","article-title":"Pneumonitis in patients receiving thoracic radiotherapy and osimertinib: a multi-institutional study","volume":"4","author":"Banla","year":"2023","journal-title":"JTO Clinical and Research Reports"},{"key":"10.1016\/j.radonc.2026.111707_b0215","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2025.53809","article-title":"Adverse events after metastases-directed stereotactic radiotherapy and biological cancer therapy","volume":"9","author":"Looman","year":"2026","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.radonc.2026.111707_b0155","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1016\/j.annonc.2025.06.007","article-title":"Updated treatment recommendations for systemic treatment: from the ESMO oncogene-addicted metastatic NSCLC living guideline","volume":"36","author":"Hendriks","year":"2025","journal-title":"Ann Oncol"},{"key":"10.1016\/j.radonc.2026.111707_b0230","doi-asserted-by":"crossref","first-page":"e73","DOI":"10.1016\/S1470-2045(23)00534-X","article-title":"International multidisciplinary consensus on the integration of radiotherapy with new systemic treatments for breast cancer: european society for radiotherapy and oncology (ESTRO)-endorsed recommendations","volume":"25","author":"Meattini","year":"2024","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.radonc.2026.111707_b0175","doi-asserted-by":"crossref","DOI":"10.1016\/j.radonc.2025.110898","article-title":"Stereotactic reirradiation for in-field lung cancer recurrence after stereotactic ablative radiotherapy: a systematic review and meta-analysis","volume":"208","author":"Jang","year":"2025","journal-title":"Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology"}],"container-title":["Radiotherapy and Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814026005463?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814026005463?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T12:19:06Z","timestamp":1786796346000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167814026005463"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":72,"alternative-id":["S0167814026005463"],"URL":"https:\/\/doi.org\/10.1016\/j.radonc.2026.111707","relation":{},"ISSN":["0167-8140"],"issn-type":[{"value":"0167-8140","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"ESTRO clinical practice guideline on high-dose thoracic reirradiation for non-small cell lung cancer","name":"articletitle","label":"Article Title"},{"value":"Radiotherapy and Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.radonc.2026.111707","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"111707"}}