{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T03:31:48Z","timestamp":1787801508425,"version":"build-2784847793"},"reference-count":29,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,12,14]],"date-time":"2022-12-14T00:00:00Z","timestamp":1670976000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Revista Argentina de Microbiolog\u00eda"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.ram.2022.10.001","type":"journal-article","created":{"date-parts":[[2023,1,3]],"date-time":"2023-01-03T07:20:02Z","timestamp":1672730402000},"page":"160-166","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Enfermedad del legionario en Argentina: evoluci\u00f3n de la estrategia diagn\u00f3stica en el laboratorio"],"prefix":"10.1016","volume":"55","author":[{"given":"Luc\u00eda","family":"Cipolla","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florencia","family":"Rocca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita","family":"Armitano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz","family":"L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00f3nica","family":"Prieto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ram.2022.10.001_bib0150","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1378\/chest.13-0162","article-title":"Importance of Legionella pneumophila in the etiology of severe community-acquired pneumonia in Santiago, Chile","volume":"145","author":"Arancibia","year":"2014","journal-title":"Chest."},{"key":"10.1016\/j.ram.2022.10.001_bib0155","unstructured":"Australian Government, Department of Health, Legionella laboratory case definition (LCD). [Internet]. Australia; 2019 [actualizado 15 Jul 2021; citado 26 Jun 2022]. Disponible en: https:\/\/www1.health.gov.au\/internet\/main\/publishing.nsf\/Content\/cda-pubs-annlrpt-nndssar.htm"},{"key":"10.1016\/j.ram.2022.10.001_bib0160","series-title":"Legionella and the prevention of legionellosis","author":"Bartram","year":"2007"},{"key":"10.1016\/j.ram.2022.10.001_bib0165","doi-asserted-by":"crossref","first-page":"656","DOI":"10.7326\/0003-4819-90-4-656","article-title":"Classification of the Legionnaires\u2019 disease bacterium: Legionella pneumophila, genus novum, species nova, of the family Legionellaceae, familia nova","volume":"90","author":"Brenner","year":"1979","journal-title":"Ann Intern Med."},{"key":"10.1016\/j.ram.2022.10.001_bib0170","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s41479-020-00080-5","article-title":"Legionnaires\u2019 disease in the time of COVID-19","volume":"13","author":"Cassell","year":"2021","journal-title":"Pneumonia."},{"key":"10.1016\/j.ram.2022.10.001_bib0175","unstructured":"Centers for Disease Control and Prevention. Legionnaires disease case definitions. [Internet]. USA: CDC; 2019 [consultado 18 Abr 2022]. Disponible en: https:\/\/www.cdc.gov\/legionella\/health-depts\/surv-reporting\/case-definitions.html"},{"key":"10.1016\/j.ram.2022.10.001_bib0180","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1016\/j.rmed.2005.02.008","article-title":"Community-acquired pneumonia by Legionella pneumophila serogroups 1-6 in Brazil","volume":"99","author":"Chedid","year":"2005","journal-title":"Respir Med."},{"key":"10.1016\/j.ram.2022.10.001_bib0185","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/S0140-6736(15)60078-2","article-title":"Legionnaires\u2019 disease","volume":"387","author":"Cunha","year":"2016","journal-title":"Lancet."},{"key":"10.1016\/j.ram.2022.10.001_bib0190","unstructured":"Direcci\u00f3n de Epidemiolog\u00eda de la Provincia de Buenos Aires - Ministerio de Salud de la Provincia de Buenos Aires. Brote de enfermedad respiratoria aguda grave por Legionella spp. en Hospital Nuestra Sra. del Carmen de la localidad de Carmen de Areco [Internet]. 2013 [consultado 18 Abr 2022]. Disponible en: https:\/\/docplayer.es\/6445631-Brote-de-enfermedad-respiratoria-aguda-grave-por-legionella-spp-en-hospital-nuestra-sra-del-carmen-de-la-localidad-de-carmen-de-areco.html"},{"key":"10.1016\/j.ram.2022.10.001_bib0195","series-title":"Mandell, Douglas, and Bennett's principles and poractice of infectious diseases","first-page":"2633","article-title":"Legionnaires\u2019 disease and Pontiac Fever","author":"Edelstein","year":"2015"},{"key":"10.1016\/j.ram.2022.10.001_bib0200","unstructured":"European Centre for Disease Prevention and Control. EU case definitions. [Internet]. EU; 2018 [citado 26 Jun 2022]. Disponible en: https:\/\/www.ecdc.europa.eu\/en\/surveillance-and-disease-data\/eu-case-definitions"},{"key":"10.1016\/j.ram.2022.10.001_bib0205","unstructured":"European Centre for Disease Prevention and Control. Legionnaires\u2019 disease. En: ECDC. Annual epidemiological report for 2019. [Internet]. Stockholm: ECDC; 2021 [citado 26 Jun 2022]. Disponible en: https:\/\/www.ecdc.europa.eu\/en\/publications-data\/legionnaires-disease-annual-epidemiological-report-2019"},{"key":"10.1016\/j.ram.2022.10.001_bib0210","doi-asserted-by":"crossref","first-page":"3452","DOI":"10.1128\/JCM.41.7.3452-3453.2003","article-title":"Contamination of Qiagen DNA extraction kits with Legionella DNA","volume":"41","author":"Evans","year":"2003","journal-title":"J Clin Microbiol."},{"key":"10.1016\/j.ram.2022.10.001_bib0215","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1056\/NEJM197712012972201","article-title":"Legionnaires\u2019 disease: Description of an epidemic of pneumonia","volume":"297","author":"Fraser","year":"1977","journal-title":"N Engl J Med."},{"key":"10.1016\/j.ram.2022.10.001_bib0220","doi-asserted-by":"crossref","first-page":"576","DOI":"10.15585\/mmwr.mm6522e1","article-title":"Vital signs: Deficiencies in environmental control identified in outbreaks of Legionnaires\u2019 disease\u2014North America, 2000-2014","volume":"65","author":"Garrison","year":"2016","journal-title":"MMWR Morb Mortal Wkly Rep."},{"key":"10.1016\/j.ram.2022.10.001_bib0225","doi-asserted-by":"crossref","first-page":"2841","DOI":"10.1128\/jcm.35.11.2841-2845.1997","article-title":"Antigenic lipopolysaccharide components of Legionella pneumophila recognized by monoclonal antibodies: Possibilities and limitations for division of the species into serogroups","volume":"35","author":"Helbig","year":"1997","journal-title":"J Clin Microbiol."},{"key":"10.1016\/j.ram.2022.10.001_bib0230","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1007\/s10096-011-1492-7","article-title":"Legionella pneumophila urinary antigen subtyping using monoclonal antibodies as a tool for epidemiological investigations","volume":"31","author":"Helbig","year":"2012","journal-title":"Eur J Clin Microbiol Infect Dis."},{"key":"10.1016\/j.ram.2022.10.001_bib0235","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1097\/QCO.0000000000000468","article-title":"Legionella: A reemerging pathogen","volume":"31","author":"Herwaldt","year":"2018","journal-title":"Curr Opin Infect Dis."},{"key":"10.1016\/j.ram.2022.10.001_bib0240","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/978-1-62703-161-5_2","article-title":"Identification of Legionella in clinical samples","volume":"954","author":"Jarraud","year":"2013","journal-title":"Methods Mol Biol."},{"key":"10.1016\/j.ram.2022.10.001_bib0245","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.medcli.2015.10.009","article-title":"Neumon\u00eda por Legionella, \u00bfcu\u00e1ndo solicitar la antigenuria en orina?","volume":"146","author":"Jodra S\u00e1nchez","year":"2016","journal-title":"Med Clin."},{"key":"10.1016\/j.ram.2022.10.001_bib0250","first-page":"19","article-title":"Presencia de especies de Legionella en reservorios domiciliarios de agua de Resistencia Chaco, Argentina","volume":"10","author":"Losch","year":"2019","journal-title":"Rev Argent Salud P\u00fablica."},{"key":"10.1016\/j.ram.2022.10.001_bib0255","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1378\/chest.118.5.1344","article-title":"Community-acquired pneumonia: Etiology, epidemiology, and outcome at a teaching hospital in Argentina","volume":"118","author":"Luna","year":"2000","journal-title":"Chest."},{"key":"10.1016\/j.ram.2022.10.001_bib0260","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1056\/NEJM197712012972202","article-title":"Legionnaires\u2019 disease: Isolation of a bacterium and demonstration of its role in other respiratory disease","volume":"297","author":"McDade","year":"1977","journal-title":"N Engl J Med."},{"key":"10.1016\/j.ram.2022.10.001_bib0265","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1080\/00365540110026764","article-title":"Molecular diagnosis of infective endocarditis--a new Duke's criterion","volume":"33","author":"Millar","year":"2001","journal-title":"Scand J Infect Dis."},{"key":"10.1016\/j.ram.2022.10.001_bib0270","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.ajic.2009.04.285","article-title":"Legionella species colonization in cooling towers: Risk factors and assessment of control measures","volume":"38","author":"Mouchtouri","year":"2010","journal-title":"Am J Infect Control."},{"key":"10.1016\/j.ram.2022.10.001_bib0275","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1007\/s10096-019-03785-8","article-title":"What is the risk of missing legionellosis relying on urinary antigen testing solely? A retrospective Belgian multicenter study","volume":"39","author":"Muyldermans","year":"2020","journal-title":"Eur J Clin Microbiol Infect Dis."},{"key":"10.1016\/j.ram.2022.10.001_bib0280","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jinf.2019.11.021","article-title":"Rapid syndromic molecular testing in pneumonia: The current landscape and future potential","volume":"80","author":"Poole","year":"2020","journal-title":"J Infect."},{"key":"10.1016\/j.ram.2022.10.001_bib0285","unstructured":"Public Health England Legionnaires\u2019 disease case definitions [Internet]. England. [actualizado 6 Feb 2020; citado 26 Jun 2022]. Disponible en: https:\/\/www.gov.uk\/government\/publications\/legionnaires-disease-clinical-case-definitions\/legionnaires-disease-case-definitions"},{"key":"10.1016\/j.ram.2022.10.001_bib0290","series-title":"Legionelosis. Manual de procedimientos para el diagn\u00f3stico microbiol\u00f3gico","author":"Prieto","year":"2021"}],"container-title":["Revista Argentina de Microbiolog\u00eda"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0325754122001031?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0325754122001031?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T04:59:19Z","timestamp":1759726759000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0325754122001031"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["S0325754122001031"],"URL":"https:\/\/doi.org\/10.1016\/j.ram.2022.10.001","relation":{},"ISSN":["0325-7541"],"issn-type":[{"value":"0325-7541","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Enfermedad del legionario en Argentina: evoluci\u00f3n de la estrategia diagn\u00f3stica en el laboratorio","name":"articletitle","label":"Article Title"},{"value":"Revista Argentina de Microbiolog\u00eda","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ram.2022.10.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Asociaci\u00f3n Argentina de Microbiolog\u00eda. Published by Elsevier Espa\u00f1a, S.L.U.","name":"copyright","label":"Copyright"}]}}