{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T14:42:43Z","timestamp":1789569763678,"version":"build-2803163510"},"reference-count":34,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T00:00:00Z","timestamp":1737504000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010324","name":"National University of the Northeast General Secretariat of Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010324","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Revista Argentina de Microbiolog\u00eda"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.ram.2024.12.013","type":"journal-article","created":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T16:58:37Z","timestamp":1740070717000},"page":"349-355","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Colistin-resistant Escherichia coli mediated by the mcr-1 gene from pigs in northeastern Argentina"],"prefix":"10.1016","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1546-3940","authenticated-orcid":false,"given":"Juan Leandro","family":"Pellegrini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda de los \u00c1ngeles","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liliana Silvina","family":"L\u00f6sch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis Antonio","family":"Merino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Alejandro","family":"Di Conza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ram.2024.12.013_bib0175","doi-asserted-by":"crossref","first-page":"465","DOI":"10.3390\/antibiotics10040465","article-title":"The effect of colistin treatment on the selection of colistin-resistant Escherichia coli in weaner pigs","volume":"10","author":"Ahmed","year":"2021","journal-title":"Antibiotics (Basel)"},{"key":"10.1016\/j.ram.2024.12.013_bib0180","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1080\/03079457.2018.1524573","article-title":"A review on the current situation and challenges of colistin resistance in poultry production","volume":"47","author":"Apostolakos","year":"2018","journal-title":"Avian Pathol"},{"key":"10.1016\/j.ram.2024.12.013_bib0185","series-title":"Bergey's manual of systematics of archaea and bacteria","first-page":"1","article-title":"Enterobacteriaceae","author":"Brenner","year":"2015"},{"key":"10.1016\/j.ram.2024.12.013_bib0190","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.3390\/antibiotics11121781","article-title":"Occurrence and genomic characterization of mcr-1-harboring Escherichia coli isolates from chicken and pig farms in Lima, Peru","volume":"11","author":"Carhuaricra","year":"2022","journal-title":"Antibiotics (Basel)"},{"key":"10.1016\/j.ram.2024.12.013_bib0195","series-title":"Performance standards for antimicrobial susceptibility testing; Thirty-fourth informational supplement. M100-S34. Wayne, PA, USA","year":"2024"},{"key":"10.1016\/j.ram.2024.12.013_bib0200","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.3389\/fmicb.2018.01679","article-title":"Simultaneous carriage of mcr-1 and other antimicrobial resistance determinants in Escherichia coli from poultry","volume":"9","author":"Dominguez","year":"2018","journal-title":"Front Microbiol"},{"key":"10.1016\/j.ram.2024.12.013_bib0205","series-title":"Breakpoint tables for interpretation of MICs and zone diameters. Version 11.0","year":"2024"},{"key":"10.1016\/j.ram.2024.12.013_bib0210","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.jgar.2019.03.011","article-title":"Multidrug-resistant Escherichia coli harbouring mcr-1 and blaCTX-M genes isolated from swine in Argentina","volume":"18","author":"Faccone","year":"2019","journal-title":"J Glob Antimicrob Resist"},{"key":"10.1016\/j.ram.2024.12.013_bib0215","doi-asserted-by":"crossref","first-page":"e55","DOI":"10.26633\/RPSP.2020.55","article-title":"Mobilizable colistin resistance group plasmidic resistance to colistin mediated by mcr-1 gene in Escherichia coli clinical isolates in Argentina: a retrospective study, 2012\u20132018","volume":"44","author":"Faccone","year":"2020","journal-title":"Rev Panam Salud Publica"},{"key":"10.1016\/j.ram.2024.12.013_bib0220","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES.2016.21.17.30214","article-title":"Silent dissemination of colistin-resistant Escherichia coli in South America could contribute to the global spread of the mcr-1 gene","volume":"21","author":"Fernandes","year":"2016","journal-title":"Euro Surveill"},{"key":"10.1016\/j.ram.2024.12.013_bib0225","doi-asserted-by":"crossref","first-page":"067","DOI":"10.24215\/15142590e067","article-title":"Aislamientos de Escherichia coli de origen porcino resistentes a antimicrobianos de importancia cr\u00edtica para la salud p\u00fablica","volume":"42","author":"G\u00f3mez","year":"2022","journal-title":"Analecta Vet"},{"key":"10.1016\/j.ram.2024.12.013_bib0230","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.jgar.2022.01.014","article-title":"Genomic characterisation of an mcr-1 and mcr-3-producing Escherichia coli strain isolated from pigs in France","volume":"28","author":"Hamame","year":"2022","journal-title":"J Glob Antimicrob Resist"},{"key":"10.1016\/j.ram.2024.12.013_bib0235","doi-asserted-by":"crossref","first-page":"2897","DOI":"10.1007\/s11033-021-06307-y","article-title":"Mobilized colistin resistance (mcr) genes from 1 to 10: a comprehensive review","volume":"48","author":"Hussein","year":"2021","journal-title":"Mol Biol Rep"},{"key":"10.1016\/j.ram.2024.12.013_bib0240","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1186\/s13104-021-05519-6","article-title":"Molecular survey of mcr1 and mcr2 plasmid mediated colistin resistance genes in Escherichia coli isolates of animal origin in Iran","volume":"14","author":"Ilbeigi","year":"2021","journal-title":"BMC Res Notes"},{"key":"10.1016\/j.ram.2024.12.013_bib0245","doi-asserted-by":"crossref","first-page":"1208314","DOI":"10.3389\/fmicb.2023.1208314","article-title":"The occurrence and molecular detection of mcr-1 and mcr-5 genes in Enterobacteriaceae isolated from poultry and poultry meats in Malaysia","volume":"14","author":"Karim","year":"2023","journal-title":"Front Microbiol"},{"key":"10.1016\/j.ram.2024.12.013_bib0250","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.diagmicrobio.2018.04.010","article-title":"Rapid multiplex polymerase chain reaction for detection of mcr-1 to mcr-5 genes","volume":"92","author":"Lescat","year":"2018","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.ram.2024.12.013_bib0255","doi-asserted-by":"crossref","first-page":"2335","DOI":"10.1093\/jac\/dkw262","article-title":"The colistin resistance mcr-1 gene is going wild","volume":"71","author":"Liakopoulos","year":"2016","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ram.2024.12.013_bib0260","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S1473-3099(15)00424-7","article-title":"Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study","volume":"16","author":"Liu","year":"2016","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.ram.2024.12.013_bib0265","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.bsheal.2020.05.001","article-title":"Prevalence and transmission of mobilized colistin resistance (mcr) gene in bacteria common to animals and humans","volume":"2","author":"Luo","year":"2020","journal-title":"Biosafety Health"},{"key":"10.1016\/j.ram.2024.12.013_bib0270","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1111\/j.1469-0691.2011.03570.x","article-title":"Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance","volume":"18","author":"Magiorakos","year":"2012","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.ram.2024.12.013_bib0275","doi-asserted-by":"crossref","first-page":"772","DOI":"10.3390\/microorganisms12040772","article-title":"A review on colistin resistance: an antibiotic of last resort","volume":"12","author":"Mondal","year":"2024","journal-title":"Microorganisms"},{"key":"10.1016\/j.ram.2024.12.013_bib0280","series-title":"DANMAP, 2020. Use of antimicrobial agents and occurrence of antimicrobial resistance in bacteria from food animals. Food and humans in Denmark","author":"National Food Institute","year":"2021"},{"key":"10.1016\/j.ram.2024.12.013_bib0285","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES.2016.21.6.30135","article-title":"Prevalence of mcr-1 in commensal Escherichia coli from French livestock, 2007 to 2014","volume":"21","author":"Perrin-Guyomard","year":"2016","journal-title":"Euro Surveill"},{"key":"10.1016\/j.ram.2024.12.013_bib0290","doi-asserted-by":"crossref","first-page":"4412","DOI":"10.1128\/AAC.00573-16","article-title":"First description of mcr-1-mediated colistin resistance in human infections caused by Escherichia coli in Latin America","volume":"60","author":"Rapoport","year":"2016","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ram.2024.12.013_bib0295","doi-asserted-by":"crossref","first-page":"106713","DOI":"10.1016\/j.ijantimicag.2023.106713","article-title":"Colistin: from the shadows to a One Health approach for addressing antimicrobial resistance","volume":"61","author":"Rhouma","year":"2023","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.ram.2024.12.013_bib0300","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.ijantimicag.2017.03.007","article-title":"Retrospective survey of mcr-1 and mcr-2 in German pig-fattening farms, 2011\u20132012","volume":"50","author":"Roschanski","year":"2017","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.ram.2024.12.013_bib0305","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.vetmic.2019.02.006","article-title":"Co-occurrence of clinically relevant \u03b2-lactamases and MCR-1 encoding genes in Escherichia coli from companion animals in Argentina","volume":"230","author":"Rumi","year":"2019","journal-title":"Vet Microbiol"},{"key":"10.1016\/j.ram.2024.12.013_bib0310","unstructured":"Servicio Nacional de Sanidad y Calidad Agroalimentaria (SENASA). RESOL-2019-22-APN-PRES#SENASA \u2013 Productos veterinarios: prohibici\u00f3n de elaboraci\u00f3n, distribuci\u00f3n, importaci\u00f3n, uso y tenencia de colistina y sus sales. Available from: http:\/\/servicios.infoleg.gob.ar\/infolegInternet\/anexos\/315000-319999\/318811\/norma.htm [accessed 29.01.23]."},{"key":"10.1016\/j.ram.2024.12.013_bib0315","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.3390\/antibiotics12111597","article-title":"A review of resistance to polymyxins and evolving mobile colistin resistance gene (mcr) among pathogens of clinical significance","volume":"12","author":"Shahzad","year":"2023","journal-title":"Antibiotics (Basel)"},{"key":"10.1016\/j.ram.2024.12.013_bib0320","doi-asserted-by":"crossref","first-page":"e0349","DOI":"10.1590\/0037-8682-0349-2021","article-title":"Overview of polymyxin resistance in Enterobacteriaceae","volume":"55","author":"Silva","year":"2022","journal-title":"Rev Soc Bras Med Trop"},{"key":"10.1016\/j.ram.2024.12.013_bib0325","doi-asserted-by":"crossref","first-page":"102028","DOI":"10.1016\/j.tmaid.2021.102028","article-title":"Acquisition of antimicrobial resistance determinants in Enterobacterales by international travelers from a large urban setting in Brazil","volume":"41","author":"Tufic-Garutti","year":"2021","journal-title":"Travel Med Infect Dis"},{"key":"10.1016\/j.ram.2024.12.013_bib0330","doi-asserted-by":"crossref","first-page":"6823","DOI":"10.1093\/nar\/19.24.6823","article-title":"Distribution of repetitive DNA sequences in eubacteria and application to fingerprinting of bacterial genomes","volume":"19","author":"Versalovic","year":"1991","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.ram.2024.12.013_bib0335","series-title":"Monitoring and evaluation of the global action plan on antimicrobial resistance: framework and recommended indicators","author":"World Health Organization","year":"2019"},{"key":"10.1016\/j.ram.2024.12.013_bib0340","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1186\/s13104-019-4144-0","article-title":"Colistin-resistant Escherichia coli with mcr genes in the livestock of rural small-scale farms in Ecuador","volume":"12","author":"Yamamoto","year":"2019","journal-title":"BMC Res Notes"}],"container-title":["Revista Argentina de Microbiolog\u00eda"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0325754125000070?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0325754125000070?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T07:19:32Z","timestamp":1765523972000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0325754125000070"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":34,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["S0325754125000070"],"URL":"https:\/\/doi.org\/10.1016\/j.ram.2024.12.013","relation":{},"ISSN":["0325-7541"],"issn-type":[{"value":"0325-7541","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Colistin-resistant Escherichia coli mediated by the mcr-1 gene from pigs in northeastern Argentina","name":"articletitle","label":"Article Title"},{"value":"Revista Argentina de Microbiolog\u00eda","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ram.2024.12.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Espa\u00f1a, S.L.U. on behalf of Asociaci\u00f3n Argentina de Microbiolog\u00eda.","name":"copyright","label":"Copyright"}]}}