{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:36:34Z","timestamp":1787168194084,"version":"build-2736575974"},"reference-count":35,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2015,8,1]],"date-time":"2015-08-01T00:00:00Z","timestamp":1438387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","rbmojournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Reproductive BioMedicine Online"],"published-print":{"date-parts":[[2015,8]]},"DOI":"10.1016\/j.rbmo.2015.04.008","type":"journal-article","created":{"date-parts":[[2015,5,8]],"date-time":"2015-05-08T12:15:23Z","timestamp":1431087323000},"page":"192-198","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"title":["Early pregnancy care over time: should we promote an early pregnancy assessment unit?"],"prefix":"10.1016","volume":"31","author":[{"given":"Merel M.J.","family":"van den Berg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariette","family":"Goddijn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Willem M.","family":"Ankum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmy E.","family":"van Woerden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fulco","family":"van der Veen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madelon","family":"van Wely","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra J.","family":"Hajenius","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.rbmo.2015.04.008_bib0010","author":"Association of Early Pregnancy Units"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0015","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1001\/jama.2012.362","article-title":"Eliminating waste in US health care","volume":"307","author":"Berwick","year":"2012","journal-title":"JAMA"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0020","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1136\/bmj.302.6776.577","article-title":"Management of women referred to early pregnancy assessment unit: care and cost effectiveness","volume":"302","author":"Bigrigg","year":"1991","journal-title":"BMJ"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0025","doi-asserted-by":"crossref","first-page":"f197","DOI":"10.1136\/bmj.f197","article-title":"NICE guidance on ectopic pregnancy and miscarriage restricts access and choice and may be clinically unsafe","volume":"346","author":"Bourne","year":"2013","journal-title":"BMJ"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0030","series-title":"Ectopic pregnancy mortality \u2013 Florida","author":"Centre for Disease Control and Prevention","year":"2012"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0035","series-title":"Pharmacotherapeutic compass","author":"College voor Zorgverzekeringen (CVZ) [Health insurance Board]","year":"2014"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0040","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1046\/j.1365-2044.1999.00854.x","article-title":"Why mothers die\u2013report on confidential enquiries into maternal deaths in the United Kingdom 1994-96","volume":"54","author":"Crowhurst","year":"1999","journal-title":"Anaesthesia"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0045","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1093\/humupd\/dmq004","article-title":"The patients' perspective on fertility care: a systematic review","volume":"16","author":"Dancet","year":"2010","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0050","doi-asserted-by":"crossref","first-page":"1743","DOI":"10.1001\/jama.1988.03410120089033","article-title":"The quality of care. How can it be assessed?","volume":"260","author":"Donabedian","year":"1988","journal-title":"JAMA"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0055","series-title":"Guideline: Recurrent Miscarriage","author":"Dutch Society of Obstetrics and Gynaecology (NVOG)","year":"2007"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0060","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1136\/bmj.38498.669595.8F","article-title":"Selective chromosome analysis in couples with two or more miscarriages: case-control study","volume":"331","author":"Franssen","year":"2005","journal-title":"Br. Med. J."},{"key":"10.1016\/j.rbmo.2015.04.008_bib0065","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1093\/humrep\/dem014","article-title":"Management of recurrent miscarriage: evaluating the impact of a guideline","volume":"22","author":"Franssen","year":"2007","journal-title":"Hum. Reprod"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0070","first-page":"A601","article-title":"Problems in early pregnancy require special care: \u2018early pregnancy units","volume":"153","author":"Goddijn","year":"2009","journal-title":"Ned. Tijdschr. Geneeskd"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0075","doi-asserted-by":"crossref","first-page":"1894","DOI":"10.1093\/humrep\/deh344","article-title":"Misoprostol versus curettage in women with early pregnancy failure after initial expectant management: a randomized trial","volume":"19","author":"Graziosi","year":"2004","journal-title":"Hum. Reprod"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0085","author":"HAG-desk AMC"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0080","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1002\/uog.2801","article-title":"Impact of the availability of sonography in the acute gynecology unit","volume":"28","author":"Haider","year":"2006","journal-title":"Ultrasound Obstet. Gynecol"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0090","doi-asserted-by":"crossref","first-page":"419","DOI":"10.4103\/1119-3077.134003","article-title":"Current approaches for assessment and treatment of women with early miscarriage or ectopic pregnancy in Nigeria: a case for dedicated early pregnancy services","volume":"17","author":"Iyoke","year":"2014","journal-title":"Niger. J. Clin. Pract"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0095","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1016\/j.fertnstert.2009.01.166","article-title":"Diagnostic factors identified in 1020 women with two versus three or more recurrent pregnancy losses","volume":"93","author":"Jaslow","year":"2010","journal-title":"Fertil. Steril"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0100","doi-asserted-by":"crossref","first-page":"2216","DOI":"10.1093\/humrep\/del150","article-title":"Evidence-based guidelines for the investigation and medical treatment of recurrent miscarriage","volume":"21","author":"Jauniaux","year":"2006","journal-title":"Hum. Reprod"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0105","doi-asserted-by":"crossref","first-page":"e8136","DOI":"10.1136\/bmj.e8136","article-title":"Ectopic pregnancy and miscarriage: summary of NICE guidance","volume":"345","author":"Newbatt","year":"2012","journal-title":"BMJ"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0110","series-title":"NICE Clinical Guideline: Ectopic pregnancy and miscarriage","author":"NHS National Institute for Health and Clinical Excellence","year":"2012"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0115","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1111\/j.1479-828X.2009.00954.x","article-title":"The early pregnancy assessment project: the effect of cooperative care in the emergency department for management of early pregnancy complications","volume":"49","author":"O'Rourke","year":"2009","journal-title":"Aust. N. Z. J. Obstet. Gynaecol"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0120","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/S0140-6736(06)69204-0","article-title":"Recurrent miscarriage","volume":"368","author":"Rai","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0125","doi-asserted-by":"crossref","first-page":"2913","DOI":"10.1093\/humrep\/deq202","article-title":"Identification of copy number variants in miscarriages from couples with idiopathic recurrent pregnancy loss","volume":"25","author":"Rajcan-Separovic","year":"2010","journal-title":"Hum. Reprod"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0130","doi-asserted-by":"crossref","first-page":"2638","DOI":"10.1093\/humrep\/deg505","article-title":"High ratings of satisfaction with fertility treatment are common: findings from the Copenhagen Multi-centre Psychosocial Infertility (COMPI) Research Programme","volume":"18","author":"Schmidt","year":"2003","journal-title":"Hum. Reprod"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0135","first-page":"505","article-title":"Early pregnancy assessment units","volume":"58","author":"Shillito","year":"1997","journal-title":"Br. J. Hosp. Med"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0140","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1111\/j.1600-0412.1997.tb07990.x","article-title":"The incidence of ectopic pregnancy in Hordaland County, Norway 1976\u20131993","volume":"76","author":"Storeide","year":"1997","journal-title":"Acta Obstet. Gynecol. Scand"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0145","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1111\/j.1471-0528.1991.tb13398.x","article-title":"The miscarriage clinic: an audit of the first year","volume":"98","author":"Turner","year":"1991","journal-title":"Br. J. Obstet. Gynaecol"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0150","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.rbmo.2009.11.016","article-title":"Development of guideline-based quality indicators for recurrent miscarriage","volume":"20","author":"van den Boogaard","year":"2010","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0155","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1093\/humrep\/der179","article-title":"Selective karyotyping in recurrent miscarriage: are recommended guidelines adopted in daily clinical practice?","volume":"26","author":"van den Boogaard","year":"2011","journal-title":"Hum. Reprod"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0160","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1093\/humrep\/dep362","article-title":"Weaknesses, strengths and needs in fertility care according to patients","volume":"25","author":"van Empel","year":"2010","journal-title":"Hum. Reprod"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0165","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1093\/humrep\/des373","article-title":"Methotrexate or expectant management in women with an ectopic pregnancy or pregnancy of unknown location and low serum hCG concentrations? A randomized comparison","volume":"28","author":"van Mello","year":"2013","journal-title":"Hum. Reprod"},{"issue":"e1","key":"10.1016\/j.rbmo.2015.04.008_bib0170","doi-asserted-by":"crossref","first-page":"e50","DOI":"10.1136\/emermed-2013-202887","article-title":"An outcomes evaluation of an emergency department early pregnancy assessment service and early pregnancy assessment protocol","volume":"31","author":"Wendt","year":"2014","journal-title":"Emerg. Med. J."},{"key":"10.1016\/j.rbmo.2015.04.008_bib0175","doi-asserted-by":"crossref","first-page":"2445","DOI":"10.1093\/humrep\/17.9.2445","article-title":"Management of miscarriage: a randomized controlled trial of expectant management versus surgical evacuation","volume":"17","author":"Wieringa-de","year":"2002","journal-title":"Hum. Reprod"},{"key":"10.1016\/j.rbmo.2015.04.008_bib0180","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1108\/02689239710195251","article-title":"A cost-effectiveness study of changing medical practice in early pregnancy","volume":"11","author":"Wren","year":"1997","journal-title":"J. Manag. Med"}],"container-title":["Reproductive BioMedicine Online"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S147264831500200X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S147264831500200X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,22]],"date-time":"2018-09-22T15:27:34Z","timestamp":1537630054000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S147264831500200X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8]]},"references-count":35,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,8]]}},"alternative-id":["S147264831500200X"],"URL":"https:\/\/doi.org\/10.1016\/j.rbmo.2015.04.008","relation":{},"ISSN":["1472-6483"],"issn-type":[{"value":"1472-6483","type":"print"}],"subject":[],"published":{"date-parts":[[2015,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Early pregnancy care over time: should we promote an early pregnancy assessment unit?","name":"articletitle","label":"Article Title"},{"value":"Reproductive BioMedicine Online","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rbmo.2015.04.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}