{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T05:11:08Z","timestamp":1783487468719,"version":"3.55.0"},"reference-count":108,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100013845","name":"Fondation contre le Cancer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013845","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","rbmojournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Reproductive BioMedicine Online"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1016\/j.rbmo.2020.05.017","type":"journal-article","created":{"date-parts":[[2020,6,9]],"date-time":"2020-06-09T11:45:54Z","timestamp":1591703154000},"page":"431-442","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":44,"title":["Hormone therapy for intramural myoma-related infertility from ulipristal acetate to GnRH antagonist: a review"],"prefix":"10.1016","volume":"41","author":[{"given":"Jacques","family":"Donnez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Madeleine","family":"Dolmans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.rbmo.2020.05.017_bib0003","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1067\/mob.2003.99","article-title":"High cumulative invidence of uterine leiomyoma in black and white women: ultrasound evidence","volume":"188","author":"Baird","year":"2003","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0004","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1097\/01.EDE.0000054360.61254.27","article-title":"Why is parity protective for uterine fibroids?","volume":"14","author":"Baird","year":"2003","journal-title":"Epidemiology"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0005","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1016\/j.jmig.2018.03.005","article-title":"The Effect of Intramural Myomas Without an Intracavity Component on In Vitro Fertilization Outcomes in Single Fresh Blastocyst Transfer Cycles","volume":"25","author":"Behbehani","year":"2018","journal-title":"J. Minim. Invasive Gynecol."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0006","doi-asserted-by":"crossref","first-page":"111","DOI":"10.5301\/je.5000253","article-title":"Ignacio Rodriguez Effect of Non-Cavity Distorting Intramural Fibroids on Assisted Reproduction Outcomes: A Cohort Study","volume":"88","author":"Marqueta","year":"2016","journal-title":"Journal of Endometriosis and Pelvic pain disorders"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0007","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/j.rbmo.2010.06.039","article-title":"Endometrial implantation factors in women with submucous uterine fibroids","volume":"21","author":"Ben-Nagi","year":"2010","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0008","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1586\/17446651.2014.862495","article-title":"The potential of selective progesterone receptor modulators for the treatment of uterine fibroids","volume":"9","author":"Bestel","year":"2014","journal-title":"Expert Rev. Endocrinol. Metab."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0009","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1097\/01.gco.0000084241.09900.c8","article-title":"What does \u2018diagnostic hysteroscopy\u2019 mean today? The role of the new techniques","volume":"15","author":"Bettocchi","year":"2003","journal-title":"Curr. Opin. Obstet. Gynecol."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0010","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S1074-3804(05)60012-6","article-title":"Operative office hysteroscopy without anesthesia: analysis of 4863 cases performed with mechanical instruments","volume":"11","author":"Bettocchi","year":"2004","journal-title":"J. Am. Assoc. Gynecol. Laparosc."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0011","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1016\/j.fertnstert.2011.08.021","article-title":"Selective progesterone receptor modulators in reproductive medicine; pharmacology, clinical efficacy and safety","volume":"96","author":"Bouchard","year":"2011","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0012","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1056\/NEJMra1209993","article-title":"Uterine Fibroids","volume":"369","author":"Bulun","year":"2013","journal-title":"The New England Journal of Medicine"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0013","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1080\/09513590600604673","article-title":"Effects of the position of fibroids on fertility","volume":"22","author":"Casini","year":"2006","journal-title":"Gynecol. Endocrinol."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0014","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1016\/j.fertnstert.2014.07.1238","article-title":"Fibroid growth and medical options for treatment","volume":"102","author":"Chabbert-Buffet","year":"2014","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0015","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/S1028-4559(09)60209-6","article-title":"Ultrasonographic evaluation of the change in uterine fibroids induced by treatment with a GnRH analog","volume":"45","author":"Chia","year":"2006","journal-title":"Taiwan J. Obstet. Gynecol."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0016","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1111\/1471-0528.14362","article-title":"Fibroids that do not distort the uterine cavity and IVF success rates: an observational study using extensive matching criteria","volume":"124","author":"Christopoulos","year":"2017","journal-title":"BJOG"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0017","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1177\/1933719114542019","article-title":"Ulipristal acetate modulates the expression and functions of activin a in leiomyoma cells","volume":"21","author":"Ciarmela","year":"2014","journal-title":"Reprod. Sci."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0018","doi-asserted-by":"crossref","DOI":"10.1177\/2284026520932468","article-title":"Series of fifty-five pregnancies following ulipristal acetate treatment of symptomatic uterine fibroids","author":"Costa","year":"2020","journal-title":"Journal of endometriosis and pelvic disorders"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0019","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.fertnstert.2015.04.025","article-title":"In vivo mechanisms of uterine myoma volume reduction with ulipristal acetate treatment","volume":"104","author":"Courtoy","year":"2015","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0020","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.rbmo.2018.04.050","article-title":"Gene expression changes in uterine myomas in response to ulipristal acetate treatment","volume":"37","author":"Courtoy","year":"2018","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0021","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1159\/000480011","article-title":"Progesterone Receptor Isoforms, Nuclear Corepressor-1 and Steroid Receptor Coactivator-1 and B-Cell Lymphoma 2 and Akt and Akt Phosphorylation Status in Uterine Myomas after Ulipristal Acetate Treatment: A Systematic Immunohistochemical Evaluation","volume":"83","author":"Courtoy","year":"2018","journal-title":"Gynecol. Obstet. Invest."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0022","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1210\/jc.2017-02295","article-title":"Matrix Metalloproteinase Activity Correlates With Uterine Myoma Volume Reduction After Ulipristal Acetate Treatment","volume":"103","author":"Courtoy","year":"2018","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0024","doi-asserted-by":"crossref","DOI":"10.1016\/j.jogc.2018.05.020","article-title":"Pregnancy Outcomes Following Ulipristal Acetate for Uterine Fibroids: A Systematic Review","volume":"40","author":"De Gasperis-Brigante","year":"2018","journal-title":"J. Obstet. Gynaecol. Can."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0025","first-page":"100","article-title":"Uterine fibroids: diagnosis and treatment","volume":"95","author":"De La Cruz","year":"2017","journal-title":"AM Fam. Physician"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0026","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1016\/j.fertnstert.2019.08.007","article-title":"Autophagy up-regulation by ulipristal acetate as a novel target mechanism in the treatment of uterine leiomyoma: an in vitro study","volume":"112","author":"Del Bello","year":"2019","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0027","doi-asserted-by":"crossref","DOI":"10.1093\/hropen\/hoz027","article-title":"A 12-month extension study to evaluate the safety and efficacy of asoprisnil in women with heavy menstrual bleeding and uterine fibroids","volume":"2019","author":"Diamond","year":"2019","journal-title":"Hum. Reprod. Open"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0028","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1093\/humupd\/dmm041","article-title":"Hysteroscopic myomectomy: a comprehensive review of surgical techniques","volume":"14","author":"Di Spiezio Sardo","year":"2008","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0029","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.jmig.2010.03.014","article-title":"Review of new office-based hysteroscopic procedures 2003\u20132009","volume":"17","author":"Di Spiezio Sardo","year":"2010","journal-title":"J. Minim. Invasive Gynecol."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0030","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.1111\/jog.12831","article-title":"Cold loops applied to bipolar resectoscope: A safe \"one-step\" myomectomy for treatment of submucosal myomas with intramural development","volume":"41","author":"Di Spiezio","year":"2015","journal-title":"J. Obstet. Gynaecol. Res."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0031","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/j.fertnstert.2014.12.099","article-title":"Leiomyoma-derived transforming growth factor-\u03b2 impairs bone morphogenetic protein-2-mediated endometrial receptivity","volume":"103","author":"Doherty","year":"2015","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0032","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1111\/jog.14002","article-title":"Uterine fibroid management: Today and tomorrow","volume":"45","author":"Dolmans","year":"2019","journal-title":"J. Obstet. Gynaecol. Res."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0033","doi-asserted-by":"crossref","DOI":"10.1016\/j.fertnstert.2020.02.114","article-title":"Treatment of endometriosis-associated pain with Linzogalix, an oral GnRH antagonist, a randomized clinical trial","author":"Donnez","year":"2020","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0034","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1080\/13697137.2018.1549216","article-title":"Fibroid management in premenopausal women","volume":"22","author":"Donnez","year":"2019","journal-title":"Climacteric"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0035","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.fertnstert.2018.06.044","article-title":"Liver injury and ulipristal acetate: an overstated tragedy?","volume":"110","author":"Donnez","year":"2018","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0036","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1080\/14740338.2018.1550070","article-title":"Liver safety parameters of ulipristal acetate for the treatment of uterine fibroids: a comprehensive review of the clinical development program","volume":"17","author":"Donnez","year":"2018","journal-title":"Expert Opin. Drug. Saf."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0037","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.rbmo.2018.04.040","article-title":"Ulipristal acetate for the management of large uterine fibroids associated with heavy bleeding: a review","volume":"37","author":"Donnez","year":"2018","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0038","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1080\/14728214.2018.1446943","article-title":"Emerging treatment options for uterine fibroids","volume":"23","author":"Donnez","year":"2018","journal-title":"Expert Opin. Emerg. Drugs"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0039","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.bpobgyn.2017.10.008","article-title":"The current place of medical therapy in uterine fibroid management","volume":"46","author":"Donnez","year":"2018","journal-title":"Best Pract. Res. Clin. Obstet. Gynaecol."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0040","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.fertnstert.2016.11.027","article-title":"Rewriting the script: time to rethink the indications for myoma surgery","volume":"107","author":"Donnez","year":"2017","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0041","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.fertnstert.2015.09.032","article-title":"Long-term medical management of uterine fibroids with ulipristal acetate","volume":"105","author":"Donnez","year":"2016","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0042","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1093\/humupd\/dmw023","article-title":"Uterine fibroid management: from the present to the future","volume":"22","author":"Donnez","year":"2016","journal-title":"Human Reprod. Update"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0043","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1080\/14740338.2016.1248943","article-title":"Safety of treatment of uterine fibroids with the selective progesterone receptor modulator, ulipristal acetate","volume":"15","author":"Donnez","year":"2016","journal-title":"Expert. Opin. Drug. Saf."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0044","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.fertnstert.2014.10.038","article-title":"Efficacy and Safety of repeated use of ulipristal acetate in uterine fibroids","volume":"103","author":"Donnez","year":"2015","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0045","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1097\/GCO.0000000000000229","article-title":"Current management of myomas: the place of medical therapy with the advent of selective progesterone receptor modulators","volume":"27","author":"Donnez","year":"2015","journal-title":"Curr. Opin. Obstet. Gynecol."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0046","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1016\/j.fertnstert.2014.02.008","article-title":"Long-term treatment of uterine fibroids with ulipristal acetate","volume":"101","author":"Donnez","year":"2014","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0047","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1056\/NEJMoa1103182","article-title":"Ulipristal acetate versus placebo for fibroid treatment before surgery","volume":"366","author":"Donnez","year":"2012","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0048","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1056\/NEJMoa1103180","article-title":"Ulipristal acetate versus leuprolide acetate for uterine fibroids","volume":"366","author":"Donnez","year":"2012","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0049","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1093\/humrep\/17.6.1424","article-title":"What are the implications of myomas on fertility? A need for a debate?","volume":"17","author":"Donnez","year":"2002","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0050","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1016\/S0015-0282(16)60723-9","article-title":"Treatment of uterine fibroids with implants of gonadotropin-releasing hormone agonist: assessment by hysterography","volume":"51","author":"Donnez","year":"1989","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0052","first-page":"325","article-title":"Uterine contractility and reproduction: new perspectives","volume":"31","author":"Fanchin","year":"2002","journal-title":"J. Gynecol. Obstet. Biol. Reprod. (Paris)"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0053","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1016\/S0015-0282(01)02841-2","article-title":"Vaginal versus oral E(2) administration: effects on endometrial thickness, uterine perfusion, and contractility","volume":"76","author":"Fanchin","year":"2001","journal-title":"Fertil. Steril."},{"issue":"12","key":"10.1016\/j.rbmo.2020.05.017_bib0054","article-title":"Safety after extended repeated use of ulipristal acetate for uterine fibroids","volume":"7","author":"Fauser","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0056","doi-asserted-by":"crossref","first-page":"101","DOI":"10.3109\/00016347609156794","article-title":"Distribution of blood flow in myomatous uteri as measured by locally injected 133Xenon","volume":"55","author":"Forssman","year":"1976","journal-title":"Acta Obstet. Gynecol. Scand."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0057","doi-asserted-by":"crossref","first-page":"21","DOI":"10.3109\/00016347609156778","article-title":"Blood flow in myomatous uteri as measured by intra-arterial 133Xenon","volume":"55","author":"Forssman","year":"1976","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0061","doi-asserted-by":"crossref","first-page":"3490","DOI":"10.1210\/jc.2008-0565","article-title":"Endometrial receptivity and implantation are not affected by the presence of uterine intramural leiomyomas: a clinical and functional genomics analysis","volume":"93","author":"Horcajadas","year":"2008","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0062","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1177\/1933719117725827","article-title":"Literature Review on the Role of Uterine Fibroids in Endometrial Function","volume":"25","author":"Ikhena","year":"2018","journal-title":"Reprod. Sci."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0063","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.fertnstert.2013.03.007","article-title":"Complex networks of multiple factors in the pathogenesis of uterine leiomyoma","volume":"100","author":"Islam","year":"2013","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0064","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1210\/jc.2012-3237","article-title":"Uterine Leiomyoma: Available Medical Treatments and New Possible Therapeutic Options","volume":"98","author":"Islam","year":"2013","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0065","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.tjog.2013.05.007","article-title":"Detection of endometrial and subendometrial vasculature on the day of embryo transfer and prediction of pregnancy during fresh in vitro fertilization cycles","volume":"53","author":"Kim","year":"2014","journal-title":"Taiwan J. Obstet. Gynecol."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0066","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.mce.2011.05.044","article-title":"The role of progesterone signaling in the pathogenesis of uterine leiomyoma","volume":"358","author":"Kim","year":"2012","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0067","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/j.rbmo.2018.12.013","article-title":"Absence of predictable long-term molecular effect of ulipristal acetate (UPA) on the endometrium","volume":"38","author":"Kolanska","year":"2019","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0068","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.jmig.2005.05.014","article-title":"Submucous myomas: a new presurgical classification to evaluate the viability of hysteroscopic surgical treatment\u2014preliminary report","volume":"12","author":"Lasmar","year":"2005","journal-title":"J. Minim. Invasive Gynecol."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0069","first-page":"1097","article-title":"Efficacy of pre-operative gonadotrophin hormone releasing analogues for women with uterine fibroids undergoing hysterectomy or myomectomy: a systematic review","volume":"109","author":"Lethaby","year":"2002","journal-title":"BJOG"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0070","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD000547","article-title":"Pre-operative GnRH analogue therapy before hysterectomy or myomectomy for uterine fibroids","author":"Lethaby","year":"2001","journal-title":"Cochrane Database Syst. Rev."},{"issue":"4","key":"10.1016\/j.rbmo.2020.05.017_bib0071","article-title":"Antifibrinolytics for heavy menstrual bleeding","author":"Lethaby","year":"2000","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0072","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1016\/j.fertnstert.2018.12.026","article-title":"Ulipristal acetate decreases active TGF-\u03b23 and its canonical signaling in uterine leiomyoma via two novel mechanisms","volume":"111","author":"Lewis","year":"2019","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0073","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1097\/AOG.0b013e3181f20177","article-title":"Tranexamic acid treatment for heavy menstrual bleeding: a randomized controlled trial","volume":"116","author":"Lukes","year":"2010","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0074","doi-asserted-by":"crossref","first-page":"h4887","DOI":"10.1136\/bmj.h4887","article-title":"Fibroids: diagnosis and management","volume":"351","author":"Lumsden","year":"2015","journal-title":"BMJ"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajog.2016.02.049","article-title":"Long-term nonsurgical control with ulipristal acetate of multiple uterine fibroids, enabling pregnancy","volume":"214","author":"Luyckx","year":"2016","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0076","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1016\/j.fertnstert.2014.07.1253","article-title":"First series of 18 pregnancies after ulipristal acetate treatment for uterine fibroids","volume":"102","author":"Luyckx","year":"2014","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2020.05.017_bib00121","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1126\/science.1208930","article-title":"MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas","volume":"334","author":"M\u00e4kinen","year":"2011","journal-title":"Science"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0077","doi-asserted-by":"crossref","first-page":"2160","DOI":"10.1056\/NEJMc1310230","article-title":"Chromothripsis in uterine leiomyomas","volume":"369","author":"Mehine","year":"2013","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0078","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/j.fertnstert.2014.06.050","article-title":"Genomics of uterine leiomyomas: insights from high-throughput sequencing","volume":"102","author":"Mehine","year":"2014","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0079","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.1093\/humrep\/del205","article-title":"Differential infiltration of macrophages and prostaglandin production by different uterine leiomyomas","volume":"21","author":"Miura","year":"2006","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0080","article-title":"Successful pregnancy after treatment with ulipristal acetate for uterine fibroids","volume":"2014","author":"Monle\u00f3n","year":"2014","journal-title":"Case Rep. Obstet. Gynecol."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0081","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijgo.2011.01.001","article-title":"FIGO classification system (PALM-COEIN) for causes of abnormal uterine bleeding in nongravid women of reproductive age. FIGO Working Group on Menstrual Disorders","volume":"113","author":"Munro","year":"2011","journal-title":"Int. J. Gynaecol. Obstet."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0082","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.jogc.2015.11.004","article-title":"Spontaneous Pregnancy Following Ulipristal Acetate Treatment in a Woman with a Symptomatic Uterine Fibroid","volume":"38","author":"Murad","year":"2016","journal-title":"J. Obstet. Gynaecol. Can."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0083","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1038\/modpathol.2008.19","article-title":"The spectrum of endometrial pathology induced by progesterone receptor modulators","volume":"21","author":"Mutter","year":"2008","journal-title":"Mod. Pathol."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0084","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1111\/1471-0528.14608","article-title":"Fibroid vascularisation assessed with three-dimensional power Doppler ultrasound is a predictor for uterine fibroid growth: a prospective cohort study","volume":"125","author":"Nieuwenhuis","year":"2018","journal-title":"BJOG"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0085","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.ejogrb.2006.07.040","article-title":"A comparison of uterine peristalsis in women with normal uteri and uterine leiomyoma by cine magnetic resonance imaging","volume":"135","author":"Orisaka","year":"2007","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0086","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1097\/AOG.0000000000003141","article-title":"Oral Gonadotropin-Releasing Hormone Antagonist Relugolix Compared With Leuprorelin Injections for Uterine Leiomyomas: A Randomized Controlled Trial","volume":"133","author":"Osuga","year":"2019","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0087","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1016\/j.fertnstert.2008.01.051","article-title":"Fibroids and infertility: an updated systematic review of the evidence","volume":"91","author":"Pritts","year":"2009","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0088","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1016\/j.fertnstert.2008.03.029","article-title":"Submucosal uterine leiomyomas have a global effect on molecular determinants of endometrial receptivity","volume":"93","author":"Rackow","year":"2010","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0089","article-title":"The Impact of Noncavity-Distorting Intramural Fibroids on Live Birth Rate in In Vitro Fertilization Cycles: A Systematic Review and Meta-Analysis","author":"Rikhraj","year":"2019","journal-title":"J. Womens Health (Larchmt)"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0090","first-page":"32","article-title":"Case report: Successful pregnancy after combined preoperative pretreatment with ulipristal acetate and laparoscopic myoma enucleation in deep-seated cervical posterior wall myoma and desire to have children","volume":"25","author":"R\u00f6mer","year":"2015","journal-title":"Journal fur Gynakologische Endokrinologie"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0092","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1093\/humrep\/15.1.89","article-title":"Quantitative assessment of subendometrial blood flow by three-dimensional-ultrasound is an important predictive factor of implantation in an in-vitro fertilization programme","volume":"15","author":"Schild","year":"2000","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0093","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1056\/NEJMoa1904351","article-title":"Elagolix for Heavy Menstrual Bleeding in Women with Uterine Fibroids","volume":"382","author":"Schlaff","year":"2020","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0094","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1002\/(SICI)1097-0096(199603)24:3<135::AID-JCU5>3.0.CO;2-I","article-title":"Transvaginal Doppler examination of uteri with myomas","volume":"24","author":"Sladkevicius","year":"1996","journal-title":"J. Clin. Ultrasound"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0095","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s11296-007-0061-1","article-title":"Hysteroscopic myomectomy","volume":"3","author":"Stamatellos","year":"2007","journal-title":"Eur. Clin. Obstet. Gynecol."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0096","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.1056\/NEJMcp1411029","article-title":"Clinical practice. Uterine fibroids","volume":"372","author":"Stewart","year":"2015","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0097","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1089\/jwh.2013.4334","article-title":"The burden of uterine fibroids for African-American women: results of a national survey","volume":"22","author":"Stewart","year":"2013","journal-title":"J. Womens Health (Larch-rnt)"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0098","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1093\/humrep\/dep396","article-title":"The effect of intramural fibroids without uterine cavity involvement on the outcome of IVF treatment: a systematic review and meta-analysis","volume":"25","author":"Sunkara","year":"2010","journal-title":"Human Reprod."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0099","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD010241.pub2","article-title":"Pre-operative endometrial thinning agents before endometrial destruction for heavy menstrual bleeding","author":"Tan","year":"2013","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0100","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1016\/j.fertnstert.2018.03.003","article-title":"Fibroids: when should they be removed to improve in vitro fertilization success?","volume":"109","author":"Taylor","year":"2018","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0101","doi-asserted-by":"crossref","DOI":"10.17116\/repro201521486-88","article-title":"Successful pregnancy after gigantic uterine fibroids treatment with the help of ulipristal acetate","volume":"21","author":"Tikhomirov","year":"2015","journal-title":"Problemy Reproduktsii"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0102","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.ejogrb.2019.09.008","article-title":"The importance of pseudocapsule preservation during hysteroscopic myomectomy","volume":"243","author":"Tinelli","year":"2019","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0103","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/2804830","article-title":"Submucous Fibroids, Fertility, and Possible Correlation to Pseudocapsule Thickness in Reproductive Surgery","volume":"2018","author":"Tinelli","year":"2018","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0104","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1177\/1933719115612929","article-title":"Expression of Endometrial Receptivity Genes Increase After Myomectomy of Intramural Leiomyomas not Distorting the Endometrial Cavity","volume":"23","author":"Unlu","year":"2016","journal-title":"Reprod. Sci."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0105","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1093\/humupd\/dmv044","article-title":"Infertility and reproductive disorders: impact of hormonal and inflammatory mechanisms on pregnancy outcome","volume":"22","author":"Vannuccini","year":"2016","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.rbmo.2020.05.017_bib00120","first-page":"8924703","article-title":"The Impact of Noncavity-Distorting Intramural Fibroids on the Efficacy of In Vitro Fertilization-Embryo Transfer: An Updated Meta-Analysis","volume":"2018","author":"Wang","year":"2018","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0106","first-page":"496","article-title":"Commentary on the article \"Pre-treatment with ulipristal acetate before ICSI procedure: a case report\" published in Menopause Review 6\/2013","volume":"6","author":"Wdowiak","year":"2013","journal-title":"Przegl\u0105d Menopauzalny"},{"key":"10.1016\/j.rbmo.2020.05.017_bib0107","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1093\/humrep\/dem026","article-title":"The effects of the selective progesterone receptor modulator asoprisnil on themorphology of uterine tissues after 3 months treatment in patients withsymptomatic uterine leiomyomata","volume":"22","author":"Williams","year":"2007","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0108","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1097\/PGP.0b013e318251035b","article-title":"Endometrial morphology after treatment of uterine fibroids with the selective progesterone receptor modulator, ulipristal acetate","volume":"31","author":"Williams","year":"2012","journal-title":"Int. J. Gynecol. Pathol."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0109","doi-asserted-by":"crossref","DOI":"10.1097\/GRF.0000000000000164","article-title":"Epidemiology of Uterine Fibroids: From Menarche to Menopause","author":"Wise","year":"2016","journal-title":"Clin. Obstet. Gynecol."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0110","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.3945\/ajcn.111.016600","article-title":"Intake of fruit, vegetables, and carotenoids in relation to risk of uterine leiomyomata","volume":"94","author":"Wise","year":"2011","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0111","doi-asserted-by":"crossref","first-page":"1746","DOI":"10.1093\/humrep\/deh309","article-title":"Risk of uterine leiomyomata in relation to tobacco, alcohol and caffeine consumption in the Black Women's Health Study","volume":"19","author":"Wise","year":"2004","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0113","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/j.fertnstert.2018.01.007","article-title":"Effect of type 3 intramural fibroids on in vitro fertilization-intracytoplasmic sperm injection outcomes: a retrospective cohort study","volume":"10","author":"Yan","year":"2018","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0114","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1016\/j.fertnstert.2013.11.023","article-title":"Effect of fibroids not distorting the endometrial cavity on the outcome of in vitro fertilization treatment: a retrospective cohort study","volume":"101","author":"Yan","year":"2014","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0115","doi-asserted-by":"crossref","first-page":"2475","DOI":"10.1093\/humrep\/deq222","article-title":"Decreased pregnancy rate is linked to abnormal uterine peristalsis caused by intramural fibroids","volume":"25","author":"Yoshino","year":"2010","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2020.05.017_bib0116","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.contraception.2010.02.011","article-title":"Intrauterine device use among women with uterine fibroids: a systematic review","volume":"82","author":"Zapata","year":"2010","journal-title":"Contraception"}],"container-title":["Reproductive BioMedicine Online"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1472648320303163?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1472648320303163?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T08:18:11Z","timestamp":1761466691000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1472648320303163"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":108,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["S1472648320303163"],"URL":"https:\/\/doi.org\/10.1016\/j.rbmo.2020.05.017","relation":{},"ISSN":["1472-6483"],"issn-type":[{"value":"1472-6483","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hormone therapy for intramural myoma-related infertility from ulipristal acetate to GnRH antagonist: a review","name":"articletitle","label":"Article Title"},{"value":"Reproductive BioMedicine Online","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rbmo.2020.05.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}