{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T02:14:47Z","timestamp":1792808087991,"version":"4.5.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","rbmojournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Reproductive BioMedicine Online"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1016\/j.rbmo.2020.11.010","type":"journal-article","created":{"date-parts":[[2020,11,23]],"date-time":"2020-11-23T22:40:57Z","timestamp":1606171257000},"page":"669-678","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Female age is associated with the optimal number of oocytes to maximize fresh live birth rates: an analysis of 256,643 fresh ART cycles"],"prefix":"10.1016","volume":"42","author":[{"given":"Ning","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yin Jun","family":"Law","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christos A.","family":"Venetis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgina M.","family":"Chambers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katie","family":"Harris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.rbmo.2020.11.010_bib0001","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1093\/humrep\/dey388","article-title":"Higher probability of live-birth in high, but not normal, responders after first frozen-embryo transfer in a freeze-only cycle strategy compared to fresh-embryo transfer: a meta-analysis","volume":"34","author":"Bosdou","year":"2019","journal-title":"Human Reproduction"},{"key":"10.1016\/j.rbmo.2020.11.010_bib0002","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1093\/humrep\/deq080","article-title":"Maternal death related to IVF in the Netherlands 1984\u20132008","volume":"25","author":"Braat","year":"2010","journal-title":"Human Reproduction"},{"key":"10.1016\/j.rbmo.2020.11.010_bib0003","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1093\/humrep\/deu272","article-title":"Can you ever collect too many oocytes?","volume":"30","author":"Briggs","year":"2015","journal-title":"Human Reproduction"},{"key":"10.1016\/j.rbmo.2020.11.010_bib0004","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1093\/humrep\/des389","article-title":"High ovarian response does not jeopardize ongoing pregnancy rates and increases cumulative pregnancy rates in a GnRH-antagonist protocol","volume":"28","author":"Fatemi","year":"2013","journal-title":"Human Reproduction"},{"key":"10.1016\/j.rbmo.2020.11.010_bib0005","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/S1043-2760(03)00075-4","article-title":"Reproductive biology and IVF: ovarian stimulation and luteal phase consequences","volume":"14","author":"Fauser","year":"2003","journal-title":"Trends in Endocrinology & Metabolism"},{"key":"10.1016\/j.rbmo.2020.11.010_bib0006","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1093\/humrep\/der092","article-title":"ESHRE consensus on the definition of \u2018poor response' to ovarian stimulation for in vitro fertilization: the Bologna criteria\u2020","volume":"26","author":"Ferraretti","year":"2011","journal-title":"Human Reproduction"},{"key":"10.1016\/j.rbmo.2020.11.010_bib0007","series-title":"Assisted reproductive technology in Australia and New Zealand 2016","author":"Fitzgerald","year":"2018"},{"key":"10.1016\/j.rbmo.2020.11.010_bib0008","doi-asserted-by":"crossref","first-page":"2728","DOI":"10.1093\/humrep\/det303","article-title":"The optimum number of oocytes in IVF treatment: an analysis of 2455 cycles in China","volume":"28","author":"Ji","year":"2013","journal-title":"Human Reproduction"},{"key":"10.1016\/j.rbmo.2020.11.010_bib0009","doi-asserted-by":"crossref","DOI":"10.1093\/humrep\/dez100","article-title":"The number of oocytes associated with maximum cumulative live birth rates per aspiration depends on female age: a population study of 221,221 treatment cycles","author":"Law","year":"2019","journal-title":"Human Reproduction"},{"key":"10.1016\/j.rbmo.2020.11.010_bib0010","first-page":"19","article-title":"The number of oocytes retrieved during IVF: a balance between efficacy and safety","volume":"32","author":"Magnusson","year":"2017","journal-title":"Human Reproduction"},{"key":"10.1016\/j.rbmo.2020.11.010_bib0011","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1093\/humrep\/dex334","article-title":"The number of oocytes retrieved during IVF: a balance between efficacy and safety","volume":"33","author":"Magnusson","year":"2018","journal-title":"Human Reproduction"},{"key":"10.1016\/j.rbmo.2020.11.010_bib0012","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1093\/humupd\/dmx031","article-title":"Is frozen embryo transfer better for mothers and babies? Can cumulative meta-analysis provide a definitive answer?","volume":"24","author":"Maheshwari","year":"2017","journal-title":"Human Reproduction Update"},{"key":"10.1016\/j.rbmo.2020.11.010_bib0013","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/S0015-0282(16)57739-5","volume":"64","author":"Munn\u00e9","year":"1995","journal-title":"Fertility and Sterility"},{"key":"10.1016\/j.rbmo.2020.11.010_bib0014","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1093\/oxfordjournals.humrep.a136940","article-title":"Is the retrieval of high numbers of oocytes desirable in patients treated with gonadotrophin-releasing hormone analogues (GnRHa) and gonadotrophins?","volume":"4","author":"Pellicer","year":"1989","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2020.11.010_bib0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.fertnstert.2018.04.039","article-title":"Cumulative live birth rates according to the number of oocytes retrieved after the first ovarian stimulation for in vitro fertilization\/intracytoplasmic sperm injection: a multicenter multinational analysis including \u223c15,000 women","volume":"110","author":"Polyzos","year":"2018","journal-title":"Fertility and Sterility"},{"key":"10.1016\/j.rbmo.2020.11.010_bib0016","doi-asserted-by":"crossref","first-page":"2005","DOI":"10.1093\/humrep\/dev149","article-title":"Sub-optimal responders following controlled ovarian stimulation: an overlooked group?","volume":"30","author":"Polyzos","year":"2015","journal-title":"Human Reproduction"},{"key":"10.1016\/j.rbmo.2020.11.010_bib0017","unstructured":"Royston, P. 2012. MFPIGEN: Stata module for modelling and displaying interactions between continuous predictors."},{"key":"10.1016\/j.rbmo.2020.11.010_bib0018","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1016\/j.fertnstert.2013.12.026","article-title":"Oocyte number as a predictor for ovarian hyperstimulation syndrome and live birth: an analysis of 256,381 in vitro fertilization cycles","volume":"101","author":"Steward","year":"2014","journal-title":"Fertility and Sterility"},{"key":"10.1016\/j.rbmo.2020.11.010_bib0019","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1093\/humrep\/der106","article-title":"Association between the number of eggs and live birth in IVF treatment: an analysis of 400 135 treatment cycles","volume":"26","author":"Sunkara","year":"2011","journal-title":"Human Reproduction"},{"key":"10.1016\/j.rbmo.2020.11.010_bib0020","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1007\/s10815-017-0990-7","article-title":"What is the best predictor of severe ovarian hyperstimulation syndrome in IVF? A cohort study","volume":"34","author":"Tarlatzi","year":"2017","journal-title":"J. Assist. Reprod. Genet."},{"key":"10.1016\/j.rbmo.2020.11.010_bib0021","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1093\/humupd\/dmg007","article-title":"Clinical management of low ovarian response to stimulation for IVF: a systematic review","volume":"9","author":"Tarlatzis","year":"2003","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.rbmo.2020.11.010_bib0022","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1016\/S0015-0282(01)02018-0","article-title":"Increasing levels of estradiol are deleterious to embryonic implantation because they directly affect the embryo","volume":"76","author":"Valbuena","year":"2001","journal-title":"Fertility and Sterility"},{"key":"10.1016\/j.rbmo.2020.11.010_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.fertnstert.2016.10.037","article-title":"How many oocytes are optimal to achieve multiple live births with one stimulation cycle? The one-and-done approach","volume":"107","author":"Vaughan","year":"2017","journal-title":"Fertility & Sterility"},{"key":"10.1016\/j.rbmo.2020.11.010_bib0024","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1093\/humrep\/deu362","article-title":"Estimating the net effect of progesterone elevation on the day of hCG on live birth rates after IVF: a cohort analysis of 3296 IVF cycles","volume":"30","author":"Venetis","year":"2015","journal-title":"Human Reproduction"},{"key":"10.1016\/j.rbmo.2020.11.010_bib0025","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1093\/humupd\/dmt014","article-title":"Progesterone elevation and probability of pregnancy after IVF: a systematic review and meta-analysis of over 60 000 cycles","volume":"19","author":"Venetis","year":"2013","journal-title":"Human Reproduction Update"},{"key":"10.1016\/j.rbmo.2020.11.010_bib0026","article-title":"Is more better? A higher oocyte yield is independently associated with more day-3 euploid embryos after ICSI","author":"Venetis","year":"2018","journal-title":"Human Reproduction"},{"key":"10.1016\/j.rbmo.2020.11.010_bib0027","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1093\/humrep\/dey374","article-title":"Methodological approaches to analyzing IVF data with multiple cycles","volume":"34","author":"Yland","year":"2018","journal-title":"Human Reproduction"}],"container-title":["Reproductive BioMedicine Online"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S147264832030626X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S147264832030626X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T08:20:19Z","timestamp":1761466819000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S147264832030626X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":27,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["S147264832030626X"],"URL":"https:\/\/doi.org\/10.1016\/j.rbmo.2020.11.010","relation":{},"ISSN":["1472-6483"],"issn-type":[{"value":"1472-6483","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Female age is associated with the optimal number of oocytes to maximize fresh live birth rates: an analysis of 256,643 fresh ART cycles","name":"articletitle","label":"Article Title"},{"value":"Reproductive BioMedicine Online","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rbmo.2020.11.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}