{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T00:42:16Z","timestamp":1776386536633,"version":"3.51.2"},"reference-count":32,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","rbmojournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Reproductive BioMedicine Online"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.rbmo.2022.06.027","type":"journal-article","created":{"date-parts":[[2022,7,6]],"date-time":"2022-07-06T23:47:38Z","timestamp":1657151258000},"page":"1145-1151","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"title":["Oral, vaginal or intramuscular progesterone in programmed frozen embryo transfer cycles: a pilot randomized controlled trial"],"prefix":"10.1016","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9015-5978","authenticated-orcid":false,"given":"Emre","family":"Pabuccu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ertug","family":"Kovanci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guler","family":"Israfilova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F\u0131rat","family":"Tulek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cem","family":"Demirel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Recai","family":"Pabuccu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.rbmo.2022.06.027_bib0001","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.rbmo.2012.10.012","article-title":"Increasing vaginal progesterone gel supplementation after frozen-thawed embryo transfer significantly increases the delivery rate","volume":"26","author":"Alsbjerg","year":"2013","journal-title":"Reprod. Biomed. Online"},{"issue":"7","key":"10.1016\/j.rbmo.2022.06.027_bib0002","doi-asserted-by":"crossref","first-page":"1874","DOI":"10.1007\/s43032-020-00376-3","article-title":"Comparable Outcomes Using Oral Dydrogesterone Vs. Micronized Vaginal Progesterone in Frozen Embryo Transfer: a Retrospective Cohort Study","volume":"28","author":"Atzmon","year":"2021","journal-title":"Reprod. Sci."},{"key":"10.1016\/j.rbmo.2022.06.027_bib0003","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/s10815-011-9691-9","article-title":"Pregnancy outcomes in oocyte donation recipients: vaginal gel versus intramuscular injection progesterone replacement","volume":"29","author":"Berger","year":"2012","journal-title":"J. Assist. Reprod. Genet."},{"issue":"5","key":"10.1016\/j.rbmo.2022.06.027_bib0004","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1093\/oxfordjournals.humrep.a137138","article-title":"Effects of natural progesterone on the morphology of the endometrium in patients with primary ovarian failure","volume":"5","author":"Bourgain","year":"1990","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2022.06.027_bib0005","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1016\/j.fertnstert.2016.01.006","article-title":"Optimal endometrial preparation for frozen embryo transfer cycles: window of implantation and progesterone support","volume":"105","author":"Casper","year":"2016","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2022.06.027_bib0006","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/0002-9378(72)90181-0","article-title":"The significance of the human corpus luteum in pregnancy maintenance. I. Preliminary studies","volume":"112","author":"Csapo","year":"1972","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.rbmo.2022.06.027_bib0007","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/0002-9378(73)90517-6","article-title":"Effects of luteectomy and progesterone replacement therapy in early pregnant patients","volume":"115","author":"Csapo","year":"1973","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.rbmo.2022.06.027_bib0008","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.fertnstert.2017.11.004","article-title":"Vitrified blastocyst transfer cycles with the use of only vaginal progesterone replacement with Endometrin have inferior ongoing pregnancy rates: results from the planned interim analysis of a three-arm randomized controlled noninferiority trial","volume":"109","author":"Devine","year":"2018","journal-title":"Fertil. Steril."},{"issue":"3","key":"10.1016\/j.rbmo.2022.06.027_bib0009","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/j.fertnstert.2021.04.013","article-title":"Intramuscular progesterone optimizes live birth from programmed frozen embryo transfer: a randomized clinical trial","volume":"116","author":"Devine","year":"2021","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2022.06.027_bib0010","series-title":"Towards reproductive certainty: fertility and genetics beyond","first-page":"378","article-title":"In vitro culture of human blastocysts","author":"Gardner","year":"1999"},{"key":"10.1016\/j.rbmo.2022.06.027_bib0011","first-page":"2212","article-title":"Oral dydrogesterone versus intravaginal micronized progesterone gel for luteal phase support in IVF: a randomized clinical trial","volume":"33","author":"Griesinger","year":"2018","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2022.06.027_bib0012","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/j.fertnstert.2018.03.034","article-title":"Oral dydrogesterone for luteal phase support in fresh in vitro fertilization cycles: a new standard?","volume":"109","author":"Griesinger","year":"2018","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2022.06.027_bib0013","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1093\/humrep\/dew120","article-title":"A randomized controlled, non-inferiority trial of modified natural versus artificial cycle for cryo-thawed embryo transfer","volume":"31","author":"Groenewoud","year":"2016","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2022.06.027_bib0014","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1007\/s10815-007-9168-z","article-title":"Intramuscular route of progesterone administration increases pregnancy rates during nondownregulated frozen embryo transfer cycles","volume":"24","author":"Haddad","year":"2007","journal-title":"J. Assist. Reprod. Genet."},{"key":"10.1016\/j.rbmo.2022.06.027_bib0015","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1016\/j.fertnstert.2012.08.007","article-title":"Intramuscular progesterone versus 8% Crinone vaginal gel for luteal phase support for day 3 cryopreserved embryo transfer","volume":"98","author":"Kaser","year":"2012","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2022.06.027_bib0017","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s10304-020-00372-5","article-title":"Pharmakokinetik und Pharmakodynamik der in der assistierten Reproduktion verwendeten Gestagene","volume":"19","author":"Kuhl","year":"2021","journal-title":"J. Gyn\u00e4kol Endokrinol"},{"key":"10.1016\/j.rbmo.2022.06.027_bib0018","doi-asserted-by":"crossref","first-page":"2437","DOI":"10.1093\/humrep\/dex316","article-title":"Low serum progesterone on the day of embryo transfer is associated with a diminished ongoing pregnancy rate in oocyte donation cycles after artificial endometrial preparation: a prospective study","volume":"32","author":"Labarta","year":"2017","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2022.06.027_bib0019","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0020-7292(95)80005-W","article-title":"Prediction of early pregnancy outcomes","volume":"51","author":"Lin","year":"1995","journal-title":"Int. J. Gynaecol. Obstet."},{"key":"10.1016\/j.rbmo.2022.06.027_bib0020","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1590\/1806-9282.20210874","article-title":"Oral dydrogesterone in frozen-thawed embryo transfer cycles","volume":"68","author":"Macedo","year":"2022","journal-title":"Rev. Assoc. Med. Bras."},{"key":"10.1016\/j.rbmo.2022.06.027_bib0021","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1016\/j.fertnstert.2016.08.047","article-title":"Obstetric and perinatal outcomes after either fresh or thawed frozen embryo transfer: an analysis of 112,432 singleton pregnancies recorded in the Human Fertilisation and Embryology Authority anonymized dataset","volume":"106","author":"Maheshwari","year":"2016","journal-title":"Fertil. Steril."},{"issue":"6","key":"10.1016\/j.rbmo.2022.06.027_bib0022","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1016\/j.fertnstert.2021.07.002","article-title":"Serum luteal phase progesterone in women undergoing frozen embryo transfer in assisted conception: a systematic review and meta-analysis","volume":"116","author":"Melo","year":"2021","journal-title":"Fertil. Steril."},{"issue":"5","key":"10.1016\/j.rbmo.2022.06.027_bib0023","article-title":"Oral dydrogesterone vs. micronized vaginal progesterone gel for luteal phase support in frozen-thawed single blastocyst transfer in good prognosis patients","volume":"50","author":"Ozer","year":"2021","journal-title":"J. Gynecol. Obstet. Hum. Reprod."},{"key":"10.1016\/j.rbmo.2022.06.027_bib0024","article-title":"Luteal phase support in fresh and frozen embryo transfer cycles","volume":"22","author":"Pabu\u00e7cu","year":"2020","journal-title":"J. Gynecol. Obstet. Hum. Reprod."},{"key":"10.1016\/j.rbmo.2022.06.027_bib0025","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1016\/j.apjr.2016.10.002","article-title":"Oral dydrogesterone for luteal support in frozen-thawed embryo transfer artificial cycles: A pilot randomized controlled trial","volume":"5","author":"Rashidi","year":"2016","journal-title":"Asian. Pac. J. Reprod."},{"issue":"8","key":"10.1016\/j.rbmo.2022.06.027_bib0026","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1093\/humrep\/deu121","article-title":"Progesterone replacement with vaginal gel versus i.m. injection: cycle and pregnancy outcomes in IVF patients receiving vitrified blastocysts","volume":"29","author":"Shapiro","year":"2014","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2022.06.027_bib0027","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1056\/NEJMoa1705334","article-title":"Transfer of fresh versus frozen embryos in ovulatory women","volume":"378","author":"Shi","year":"2018","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.rbmo.2022.06.027_bib0028","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1093\/humrep\/dex023","article-title":"A Phase III randomized controlled trial comparing the efficacy, safety and tolerability of oral dydrogesterone versus micronized vaginal progesterone for luteal support in in vitro fertilization","volume":"32","author":"Tournaye","year":"2017","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2022.06.027_bib0029","article-title":"Crinone gel for luteal phase support in frozen-thawed embryo transfer cycles: a prospective randomized clinical trial in the Chinese population","volume":"10","author":"Wang","year":"2015","journal-title":"PLoS. One"},{"issue":"Suppl 1","key":"10.1016\/j.rbmo.2022.06.027_bib0030","doi-asserted-by":"crossref","first-page":"S209","DOI":"10.1016\/S0015-0282(00)01336-4","article-title":"Vaginal progesterone therapy during programmed cycles for frozen embryo transfer: an analysis of serum progesterone levels and pregnancy rates","volume":"74","author":"Williams","year":"2000","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2022.06.027_bib0031","article-title":"Luteal phase support for assisted reproduction cycles","volume":"7","author":"Van der Linden","year":"2015","journal-title":"Cochrane Database Syst. Rev."},{"issue":"2","key":"10.1016\/j.rbmo.2022.06.027_bib0032","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1055\/s-0035-1545363","article-title":"Luteal phase support in in vitro fertilization","volume":"33","author":"Yanushpolsky","year":"2015","journal-title":"Semin. Reprod. Med."},{"key":"10.1016\/j.rbmo.2022.06.027_bib0033","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s00404-016-4217-4","article-title":"Comparison of four protocols for luteal phase support in frozen-thawed Embryo transfer cycles: a randomized clinical trial","volume":"295","author":"Zarei","year":"2017","journal-title":"Arch. Gynecol. Obstet."}],"container-title":["Reproductive BioMedicine Online"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1472648322004862?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1472648322004862?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T08:24:04Z","timestamp":1761467044000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1472648322004862"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":32,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["S1472648322004862"],"URL":"https:\/\/doi.org\/10.1016\/j.rbmo.2022.06.027","relation":{},"ISSN":["1472-6483"],"issn-type":[{"value":"1472-6483","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Oral, vaginal or intramuscular progesterone in programmed frozen embryo transfer cycles: a pilot randomized controlled trial","name":"articletitle","label":"Article Title"},{"value":"Reproductive BioMedicine Online","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rbmo.2022.06.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}