{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T06:14:18Z","timestamp":1783404858003,"version":"3.54.6"},"reference-count":71,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100007383","name":"Fondazione ART per la Ricerca sui Trapianti","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007383","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","rbmojournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Reproductive BioMedicine Online"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.rbmo.2022.07.016","type":"journal-article","created":{"date-parts":[[2022,7,31]],"date-time":"2022-07-31T02:40:50Z","timestamp":1659235250000},"page":"713-727","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["PGT for structural chromosomal rearrangements in 300 couples reveals specific risk factors but an interchromosomal effect is unlikely"],"prefix":"10.1016","volume":"46","author":[{"given":"Cagri","family":"Ogur","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Semra","family":"Kahraman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darren Karl","family":"Griffin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cigdem","family":"Cinar Yapan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet Ali","family":"Tufekci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murat","family":"Cetinkaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sehime Gulsun","family":"Temel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alper","family":"Yilmaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.rbmo.2022.07.016_bib0001","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1003025","article-title":"Embryos of Robertsonian translocation carriers exhibit a mitotic interchromosomal effect that enhances genetic instability during early development","volume":"8","author":"Alfarawati","year":"2012","journal-title":"PLoS Genetics"},{"issue":"6","key":"10.1016\/j.rbmo.2022.07.016_bib0002","doi-asserted-by":"crossref","first-page":"268","DOI":"10.3109\/19396368.2011.633682","article-title":"Interchromosomal effect analyses by sperm FISH: incidence and distribution among reorganization carriers","volume":"57","author":"Anton","year":"2011","journal-title":"Systems Biology in Reproductive Medicine"},{"issue":"3","key":"10.1016\/j.rbmo.2022.07.016_bib0003","doi-asserted-by":"crossref","first-page":"178","DOI":"10.5152\/tud.2020.19255","article-title":"Investigation of the interchromosomal effects in male carriers with structural chromosomal abnormalities using FISH","volume":"46","author":"Balasar","year":"2020","journal-title":"Turkish Journal of Urology"},{"issue":"1","key":"10.1016\/j.rbmo.2022.07.016_bib0004","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1038\/ejhg.2008.144","article-title":"Breakpoint mapping and complete analysis of meiotic segregation patterns in three men heterozygous for paracentric inversions","volume":"17","author":"Bhatt","year":"2009","journal-title":"European Journal of Human Genetics"},{"issue":"2","key":"10.1016\/j.rbmo.2022.07.016_bib0005","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/s10815-020-02054-4","article-title":"The impact of patient, embryo, and translocation characteristics on the ploidy status of young couples undergoing preimplantation genetic testing for structural rearrangements (PGT-SR) by next generation sequencing (NGS)","volume":"38","author":"Boynukalin","year":"2021","journal-title":"Journal of Assisted Reproduction and Genetics"},{"issue":"5","key":"10.1016\/j.rbmo.2022.07.016_bib0006","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/j.rbmo.2018.12.043","article-title":"Evaluation of preimplantation genetic testing based on next-generation sequencing for balanced reciprocal translocation carriers","volume":"38","author":"Cai","year":"2019","journal-title":"Reproductive Biomedicine Online"},{"issue":"3","key":"10.1016\/j.rbmo.2022.07.016_bib0007","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1007\/s10815-020-02052-6","article-title":"Clinical outcomes following preimplantation genetic testing and microdissecting junction region in couples with balanced chromosome rearrangement","volume":"38","author":"Cheng","year":"2021","journal-title":"Journal of Assisted Reproduction and Genetics"},{"key":"10.1016\/j.rbmo.2022.07.016_bib0008","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.ejogrb.2018.03.013","article-title":"Evaluation of preimplantation genetic testing for chromosomal structural rearrangement by a commonly used next generation sequencing workflow","volume":"224","author":"Chow","year":"2018","journal-title":"European Journal of Obstetrics, Gynecology, and Reproductive Biology"},{"issue":"4","key":"10.1016\/j.rbmo.2022.07.016_bib0009","doi-asserted-by":"crossref","first-page":"hoaa043","DOI":"10.1093\/hropen\/hoaa043","article-title":"ESHRE PGT Consortium data collection XVI-XVIII: cycles from 2013 to 2015","volume":"2020","author":"Coonen","year":"2020","journal-title":"Human Reproduction Open"},{"issue":"8","key":"10.1016\/j.rbmo.2022.07.016_bib0010","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1093\/humrep\/dey227","article-title":"Defining the limits of detection for chromosome rearrangements in the preimplantation embryo using next generation sequencing","volume":"33","author":"Cuman","year":"2018","journal-title":"Human Reproduction (Oxford, England)"},{"issue":"5","key":"10.1016\/j.rbmo.2022.07.016_bib0011","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1093\/oxfordjournals.humrep.a137135","article-title":"Cytogenetic studies in couples experiencing repeated pregnancy losses","volume":"5","author":"De Braekeleer","year":"1990","journal-title":"Human Reproduction (Oxford, England)"},{"issue":"2","key":"10.1016\/j.rbmo.2022.07.016_bib0012","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1093\/oxfordjournals.humrep.a137315","article-title":"Cytogenetic studies in male infertility: a review","volume":"6","author":"De Braekeleer","year":"1991","journal-title":"Human Reproduction (Oxford, England)"},{"issue":"5","key":"10.1016\/j.rbmo.2022.07.016_bib0013","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1016\/j.fertnstert.2016.01.025","article-title":"Effects of maternal age on euploidy rates in a large cohort of embryos analyzed with 24-chromosome single-nucleotide polymorphism-based preimplantation genetic screening","volume":"105","author":"Demko","year":"2016","journal-title":"Fertility and Sterility"},{"key":"10.1016\/j.rbmo.2022.07.016_bib0014","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1016\/S0015-0282(03)00252-8","article-title":"Predictive value of sperm fluorescence in situ hybridization analysis on the outcome of preimplantation genetic diagnosis for translocations","volume":"79 Suppl 3","author":"Escudero","year":"2003","journal-title":"Fertility and Sterility"},{"key":"10.1016\/j.rbmo.2022.07.016_bib0015","doi-asserted-by":"crossref","first-page":"99","DOI":"10.3389\/fendo.2019.00099","article-title":"A novel predictive model to estimate the number of mature oocytes required for obtaining at least one euploid blastocyst for transfer in couples undergoing in vitro fertilization\/intracytoplasmic sperm injection: the ART calculator","volume":"10","author":"Esteves","year":"2019","journal-title":"Frontiers in Endocrinology"},{"issue":"11","key":"10.1016\/j.rbmo.2022.07.016_bib0016","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1007\/s10815-014-0333-x","article-title":"Aneuploidy across individual chromosomes at the embryonic level in trophectoderm biopsies: changes with patient age and chromosome structure","volume":"31","author":"Franasiak","year":"2014","journal-title":"Journal of Assisted Reproduction and Genetics"},{"issue":"4","key":"10.1016\/j.rbmo.2022.07.016_bib0017","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1093\/humupd\/dmr011","article-title":"Reproductive outcome after PGD in couples with recurrent miscarriage carrying a structural chromosome abnormality: a systematic review","volume":"17","author":"Franssen","year":"2011","journal-title":"Human Reproduction Update"},{"issue":"3","key":"10.1016\/j.rbmo.2022.07.016_bib0018","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1093\/humupd\/dmr052","article-title":"The ESHRE PGD Consortium: 10 years of data collection","volume":"18","author":"Harper","year":"2012","journal-title":"Human Reproduction Update"},{"issue":"4","key":"10.1016\/j.rbmo.2022.07.016_bib0019","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1038\/35066065","article-title":"To err (meiotically) is human: the genesis of human aneuploidy","volume":"2","author":"Hassold","year":"2001","journal-title":"Nature Reviews Genetics"},{"issue":"3","key":"10.1016\/j.rbmo.2022.07.016_bib0020","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.fertnstert.2017.11.021","article-title":"Clinical outcomes in carriers of complex chromosomal rearrangements: a retrospective analysis of comprehensive chromosome screening results in seven cases","volume":"109","author":"Hu","year":"2018","journal-title":"Fertility and Sterility"},{"issue":"11","key":"10.1016\/j.rbmo.2022.07.016_bib0021","doi-asserted-by":"crossref","first-page":"2325","DOI":"10.1007\/s10815-019-01585-9","article-title":"Pregnancy outcomes of reciprocal translocation carriers with two or more unfavorable pregnancy histories: before and after preimplantation genetic testing","volume":"36","author":"Huang","year":"2019","journal-title":"Journal of Assisted Reproduction and Genetics"},{"issue":"1","key":"10.1016\/j.rbmo.2022.07.016_bib0022","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1086\/301900","article-title":"Direct evidence for suppression of recombination within two pericentric inversions in humans: a new sperm-FISH technique","volume":"63","author":"Jaarola","year":"1998","journal-title":"American Journal of Human Genetics"},{"issue":"2","key":"10.1016\/j.rbmo.2022.07.016_bib0023","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1136\/jmg.29.2.103","article-title":"Estimates of the frequency of chromosome abnormalities detectable in unselected newborns using moderate levels of banding","volume":"29","author":"Jacobs","year":"1992","journal-title":"Journal of Medical Genetics"},{"key":"10.1016\/j.rbmo.2022.07.016_bib0024","doi-asserted-by":"crossref","DOI":"10.1177\/2058915816653277","article-title":"Probability of finding at least one euploid embryo and the euploidy rate according to the number of retrieved oocytes and female age using FISH and array CGH","volume":"5","author":"Kahraman","year":"2016","journal-title":"Journal of Reproductive Biotechnology and Fertility"},{"issue":"3","key":"10.1016\/j.rbmo.2022.07.016_bib0025","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1093\/humrep\/dez309","article-title":"The birth of a baby with mosaicism resulting from a known mosaic embryo transfer: a case report","volume":"35","author":"Kahraman","year":"2020","journal-title":"Human Reproduction (Oxford, England)"},{"issue":"2","key":"10.1016\/j.rbmo.2022.07.016_bib0026","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1037\/a0028086","article-title":"On effect size","volume":"17","author":"Kelley","year":"2012","journal-title":"Psychological Methods"},{"issue":"27","key":"10.1016\/j.rbmo.2022.07.016_bib0027","first-page":"E1858","article-title":"Error-prone mammalian female meiosis from silencing the spindle assembly checkpoint without normal interkinetochore tension","volume":"109","author":"Kolano","year":"2012","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.rbmo.2022.07.016_bib0028","doi-asserted-by":"crossref","first-page":"863","DOI":"10.3389\/fpsyg.2013.00863","article-title":"Calculating and reporting effect sizes to facilitate cumulative science: a practical primer for t-tests and ANOVAs","volume":"4","author":"Lakens","year":"2013","journal-title":"Frontiers in Psychology"},{"issue":"6","key":"10.1016\/j.rbmo.2022.07.016_bib0029","doi-asserted-by":"crossref","first-page":"555","DOI":"10.4097\/kjae.2016.69.6.555","article-title":"Alternatives to P value: confidence interval and effect size","volume":"69","author":"Lee","year":"2016","journal-title":"Korean Journal of Anesthesiology"},{"key":"10.1016\/j.rbmo.2022.07.016_bib0030","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1542\/peds.32.3.326","article-title":"Autosomal disorders","volume":"32","author":"Lejeune","year":"1963","journal-title":"Pediatrics"},{"issue":"28","key":"10.1016\/j.rbmo.2022.07.016_bib0031","first-page":"57","article-title":"Epidemiology in practice: case-control studies","volume":"11","author":"Lewallen","year":"1998","journal-title":"Community Eye Health"},{"issue":"6","key":"10.1016\/j.rbmo.2022.07.016_bib0032","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1016\/j.rbmo.2021.08.017","article-title":"Effect of carriers\u2019 sex on meiotic segregation patterns and chromosome stability of reciprocal translocations","volume":"43","author":"Lin","year":"2021","journal-title":"Reproductive Biomedicine Online"},{"issue":"11\u201312","key":"10.1016\/j.rbmo.2022.07.016_bib0033","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1159\/000512847","article-title":"The effectiveness of next-generation sequencing-based preimplantation genetic testing for balanced translocation couples","volume":"160","author":"Liu","year":"2020","journal-title":"Cytogenetic and Genome Research"},{"issue":"2","key":"10.1016\/j.rbmo.2022.07.016_bib0034","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.fertnstert.2005.03.026","article-title":"Fluorescence in situ hybridization sperm analysis of six translocation carriers provides evidence of an interchromosomal effect","volume":"84","author":"Machev","year":"2005","journal-title":"Fertility and Sterility"},{"issue":"2","key":"10.1016\/j.rbmo.2022.07.016_bib0035","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.reprotox.2006.03.013","article-title":"Meiotic chromosome abnormalities in human spermatogenesis","volume":"22","author":"Martin","year":"2006","journal-title":"Reproductive Toxicology (Elmsford, N.Y.)"},{"issue":"4","key":"10.1016\/j.rbmo.2022.07.016_bib0036","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1093\/humupd\/dmn017","article-title":"Cytogenetic determinants of male fertility","volume":"14","author":"Martin","year":"2008","journal-title":"Human Reproduction Update"},{"issue":"12","key":"10.1016\/j.rbmo.2022.07.016_bib0037","doi-asserted-by":"crossref","first-page":"2547","DOI":"10.1007\/s10815-019-01593-9","article-title":"Interchromosomal effect in carriers of translocations and inversions assessed by preimplantation genetic testing for structural rearrangements (PGT-SR)","volume":"36","author":"Mateu-Brull","year":"2019","journal-title":"Journal of Assisted Reproduction and Genetics"},{"issue":"6","key":"10.1016\/j.rbmo.2022.07.016_bib0038","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1016\/j.fertnstert.2005.05.063","article-title":"Pregnancies and live births after trophectoderm biopsy and preimplantation genetic testing of human blastocysts","volume":"84","author":"McArthur","year":"2005","journal-title":"Fertility and Sterility"},{"issue":"7","key":"10.1016\/j.rbmo.2022.07.016_bib0039","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/j.tig.2017.04.001","article-title":"Mosaicism in preimplantation human embryos: when chromosomal abnormalities are the norm","volume":"33","author":"McCoy","year":"2017","journal-title":"Trends in Genetics"},{"issue":"3","key":"10.1016\/j.rbmo.2022.07.016_bib0040","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1534\/genetics.120.303656","article-title":"The interchromosomal effect: different meanings for different organisms","volume":"216","author":"Miller","year":"2020","journal-title":"Genetics"},{"issue":"4","key":"10.1016\/j.rbmo.2022.07.016_bib0041","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1111\/j.1365-2605.2004.00490.x","article-title":"Meiotic segregation of translocations during male gametogenesis","volume":"27","author":"Morel","year":"2004","journal-title":"International Journal of Andrology"},{"issue":"3","key":"10.1016\/j.rbmo.2022.07.016_bib0042","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/j.fertnstert.2003.07.034","article-title":"Meiotic segregation of a t(7;8)(q11.21;cen) translocation in two carrier brothers","volume":"81","author":"Morel","year":"2004","journal-title":"Fertility and Sterility"},{"issue":"1","key":"10.1016\/j.rbmo.2022.07.016_bib0043","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1093\/humrep\/del317","article-title":"Meiotic segregation analysis in spermatozoa of pericentric inversion carriers using fluorescence in-situ hybridization","volume":"22","author":"Morel","year":"2007","journal-title":"Human Reproduction (Oxford, England)"},{"issue":"4","key":"10.1016\/j.rbmo.2022.07.016_bib0044","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1093\/humrep\/dex031","article-title":"Euploidy rates in donor egg cycles significantly differ between fertility centers","volume":"32","author":"Munn\u00e9","year":"2017","journal-title":"Human Reproduction (Oxford, England)"},{"issue":"4","key":"10.1016\/j.rbmo.2022.07.016_bib0045","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/j.fertnstert.2007.08.002","article-title":"Substandard application of preimplantation genetic screening may interfere with its clinical success","volume":"88","author":"Munn\u00e9","year":"2007","journal-title":"Fertility and Sterility"},{"issue":"6","key":"10.1016\/j.rbmo.2022.07.016_bib0046","doi-asserted-by":"crossref","DOI":"10.1016\/j.fertnstert.2019.07.1346","article-title":"Preimplantation genetic testing for aneuploidy versus morphology as selection criteria for single frozen-thawed embryo transfer in good-prognosis patients: a multicenter randomized clinical trial","volume":"112","author":"Munn\u00e9","year":"2019","journal-title":"Fertility and Sterility"},{"key":"10.1016\/j.rbmo.2022.07.016_bib0047","series-title":"Preimplantation Genetic Testing Recent Advances in Reproductive Medicine","first-page":"49","article-title":"Preimplantation genetic testing for structural rearrangements","author":"Ogur","year":"2020"},{"issue":"5","key":"10.1016\/j.rbmo.2022.07.016_bib0048","doi-asserted-by":"crossref","DOI":"10.1016\/j.jogoh.2020.102030","article-title":"Oral dydrogesterone vs. micronized vaginal progesterone gel for luteal phase support in frozen-thawed single blastocyst transfer in good prognosis patients","volume":"50","author":"Ozer","year":"2021","journal-title":"Journal of Gynecology, Obstetrics and Human Reproduction"},{"issue":"6","key":"10.1016\/j.rbmo.2022.07.016_bib0049","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1093\/humrep\/16.6.1155","article-title":"Study of the occurrence of interchromosomal effect in spermatozoa of chromosomal rearrangement carriers by fluorescence in-situ hybridization and primed in-situ labelling techniques","volume":"16","author":"Pellestor","year":"2001","journal-title":"Human Reproduction (Oxford, England)"},{"issue":"2","key":"10.1016\/j.rbmo.2022.07.016_bib0050","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1002\/ajmg.1320550207","article-title":"Paracentric inversions in humans: a review of 446 paracentric inversions with presentation of 120 new cases","volume":"55","author":"Pettenati","year":"1995","journal-title":"American Journal of Medical Genetics"},{"key":"10.1016\/j.rbmo.2022.07.016_bib0051","series-title":"Designing and Conducting Survey Research: A Comprehensive Guide","author":"Rea","year":"2014"},{"issue":"2","key":"10.1016\/j.rbmo.2022.07.016_bib0052","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.fertnstert.2014.11.007","article-title":"First systematic experience of preimplantation genetic diagnosis for single-gene disorders, and\/or preimplantation human leukocyte antigen typing, combined with 24-chromosome aneuploidy testing","volume":"103","author":"Rechitsky","year":"2015","journal-title":"Fertility and Sterility"},{"issue":"5","key":"10.1016\/j.rbmo.2022.07.016_bib0054","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1007\/s10815-021-02152-x","article-title":"PGT-SR: the red-herring and the siren; interchromosomal effect and screening for unrelated aneuploidy","volume":"38","author":"Scriven","year":"2021","journal-title":"Journal of Assisted Reproduction and Genetics"},{"issue":"10","key":"10.1016\/j.rbmo.2022.07.016_bib0055","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1038\/ejhg.2013.9","article-title":"Benefits and drawbacks of preimplantation genetic diagnosis (PGD) for reciprocal translocations: lessons from a prospective cohort study","volume":"21","author":"Scriven","year":"2013","journal-title":"European Journal of Human Genetics"},{"issue":"13","key":"10.1016\/j.rbmo.2022.07.016_bib0056","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1002\/(SICI)1097-0223(199812)18:13<1437::AID-PD497>3.0.CO;2-P","article-title":"Chromosome translocations: segregation modes and strategies for preimplantation genetic diagnosis","volume":"18","author":"Scriven","year":"1998","journal-title":"Prenatal Diagnosis"},{"issue":"3","key":"10.1016\/j.rbmo.2022.07.016_bib0058","doi-asserted-by":"crossref","first-page":"279","DOI":"10.4300\/JGME-D-12-00156.1","article-title":"Using effect size \u2013 or why the P value is not enough","volume":"4","author":"Sullivan","year":"2012","journal-title":"Journal of Graduate Medical Education"},{"issue":"9","key":"10.1016\/j.rbmo.2022.07.016_bib0059","doi-asserted-by":"crossref","first-page":"2581","DOI":"10.1093\/humrep\/det271","article-title":"Single-nucleotide polymorphism microarray-based preimplantation genetic diagnosis is likely to improve the clinical outcome for translocation carriers","volume":"28","author":"Tan","year":"2013","journal-title":"Human Reproduction (Oxford, England)"},{"issue":"1","key":"10.1016\/j.rbmo.2022.07.016_bib0060","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/2047-217X-3-30","article-title":"Clinical outcome of preimplantation genetic diagnosis and screening using next generation sequencing","volume":"3","author":"Tan","year":"2014","journal-title":"GigaScience"},{"issue":"1","key":"10.1016\/j.rbmo.2022.07.016_bib0061","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0950-3552(05)80025-2","article-title":"Intracytoplasmic sperm injection","volume":"8","author":"Van Steirteghem","year":"1994","journal-title":"Baillieres Clinical Obstetrics and Gynaecology"},{"issue":"2","key":"10.1016\/j.rbmo.2022.07.016_bib0062","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S1472-6483(10)60961-3","article-title":"Preimplantation testing for chromosomal disorders improves reproductive outcome of poor-prognosis patients","volume":"11","author":"Verlinsky","year":"2005","journal-title":"Reproductive Biomedicine Online"},{"key":"10.1016\/j.rbmo.2022.07.016_bib0063","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s13039-019-0423-7","article-title":"Analysis of meiotic segregation modes in biopsied blastocysts from preimplantation genetic testing cycles of reciprocal translocations","volume":"12","author":"Wang","year":"2019","journal-title":"Molecular Cytogenetics"},{"key":"10.1016\/j.rbmo.2022.07.016_bib0064","first-page":"133","article-title":"Genetic factors influencing aneuploidy frequency","volume":"36","author":"Warburton","year":"1985","journal-title":"Basic Life Sciences"},{"issue":"2","key":"10.1016\/j.rbmo.2022.07.016_bib0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.fertnstert.2019.03.041","article-title":"Retrospective analysis of meiotic segregation pattern and interchromosomal effects in blastocysts from inversion preimplantation genetic testing cycles","volume":"112","author":"Xie","year":"2019","journal-title":"Fertility and Sterility"},{"issue":"1","key":"10.1016\/j.rbmo.2022.07.016_bib0066","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/s10815-017-1045-9","article-title":"Preliminary analysis of numerical chromosome abnormalities in reciprocal and Robertsonian translocation preimplantation genetic diagnosis cases with 24-chromosomal analysis with an aCGH\/SNP microarray","volume":"35","author":"Xie","year":"2018","journal-title":"Journal of Assisted Reproduction and Genetics"},{"issue":"1","key":"10.1016\/j.rbmo.2022.07.016_bib0067","doi-asserted-by":"crossref","first-page":"55","DOI":"10.2478\/bjmg-2014-0025","article-title":"The largest paracentric inversion, the highest rate of recombinant spermatozoa. Case report: 46,XY,inv(2)(q21.2q37.3) and literature review","volume":"17","author":"Yapan","year":"2014","journal-title":"Balkan Journal of Medical Genetics"},{"issue":"1","key":"10.1016\/j.rbmo.2022.07.016_bib0068","doi-asserted-by":"crossref","first-page":"e13805","DOI":"10.1111\/and.13805","article-title":"Interchromosomal effect: report of a father and son, bearing different translocations of the same chromosome, and a review of the current literature","volume":"53","author":"Y\u0131ld\u0131r\u0131m","year":"2021","journal-title":"Andrologia"},{"issue":"3","key":"10.1016\/j.rbmo.2022.07.016_bib0069","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1007\/s10815-018-1376-1","article-title":"Infertility patients with chromosome inversions are not susceptible to an inter-chromosomal effect","volume":"36","author":"Young","year":"2019","journal-title":"Journal of Assisted Reproduction and Genetics"},{"issue":"3","key":"10.1016\/j.rbmo.2022.07.016_bib0070","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.fertnstert.2017.06.005","article-title":"The International Glossary on Infertility and Fertility Care, 2017","volume":"108","author":"Zegers-Hochschild","year":"2017","journal-title":"Fertility and Sterility"},{"issue":"2","key":"10.1016\/j.rbmo.2022.07.016_bib0071","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1093\/humrep\/dey367","article-title":"Interaction of acrocentric chromosome involved in translocation and sex of the carrier influences the proportion of alternate segregation in autosomal reciprocal translocations","volume":"34","author":"Zhang","year":"2019","journal-title":"Human Reproduction (Oxford, England)"},{"issue":"9","key":"10.1016\/j.rbmo.2022.07.016_bib0072","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1007\/s10815-019-01534-6","article-title":"Effects of a carrier's sex and age on the segregation patterns of the trivalent of Robertsonian translocations","volume":"36","author":"Zhang","year":"2019","journal-title":"Journal of Assisted Reproduction and Genetics"},{"issue":"4","key":"10.1016\/j.rbmo.2022.07.016_bib0073","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1093\/humrep\/dey036","article-title":"Analysis of segregation patterns of quadrivalent structures and the effect on genome stability during meiosis in reciprocal translocation carriers","volume":"33","author":"Zhang","year":"2018","journal-title":"Human Reproduction (Oxford, England)"}],"container-title":["Reproductive BioMedicine Online"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1472648322005223?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1472648322005223?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T08:24:35Z","timestamp":1761467075000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1472648322005223"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":71,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["S1472648322005223"],"URL":"https:\/\/doi.org\/10.1016\/j.rbmo.2022.07.016","relation":{},"ISSN":["1472-6483"],"issn-type":[{"value":"1472-6483","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"PGT for structural chromosomal rearrangements in 300 couples reveals specific risk factors but an interchromosomal effect is unlikely","name":"articletitle","label":"Article Title"},{"value":"Reproductive BioMedicine Online","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rbmo.2022.07.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}