{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T14:54:18Z","timestamp":1789829658352,"version":"4.0.1"},"reference-count":29,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100002912","name":"Government of Guangdong Province","doi-asserted-by":"publisher","award":["2023P-TS45"],"award-info":[{"award-number":["2023P-TS45"]}],"id":[{"id":"10.13039\/501100002912","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010256","name":"Guangzhou Municipal Science and Technology Project","doi-asserted-by":"publisher","award":["201804020087"],"award-info":[{"award-number":["201804020087"]}],"id":[{"id":"10.13039\/501100010256","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2018YFC1003102"],"award-info":[{"award-number":["2018YFC1003102"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81270750"],"award-info":[{"award-number":["81270750"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81771588"],"award-info":[{"award-number":["81771588"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82071716"],"award-info":[{"award-number":["82071716"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","rbmojournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Reproductive BioMedicine Online"],"published-print":{"date-parts":[[2023,10]]},"DOI":"10.1016\/j.rbmo.2023.06.009","type":"journal-article","created":{"date-parts":[[2023,6,24]],"date-time":"2023-06-24T18:40:20Z","timestamp":1687632020000},"page":"103254","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Storage time does not influence pregnancy and neonatal outcomes for first single vitrified high-quality blastocyst transfer cycle"],"prefix":"10.1016","volume":"47","author":[{"given":"Yuanlin","family":"Ma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingna","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianrui","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenhui","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lok\u2011Wan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junli","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuerong","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingyun","family":"Mai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanwen","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.rbmo.2023.06.009_bib0001","first-page":"843","article-title":"Duration of storage does not influence pregnancy outcome in cryopreserved human embryos","volume":"11","author":"Aflatoonian","year":"2013","journal-title":"Iran. J. Reprod. Med."},{"key":"10.1016\/j.rbmo.2023.06.009_bib0002","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.tjog.2011.01.037","article-title":"The factors affecting the outcome of frozen-thawed embryo transfer cycle","volume":"50","author":"Ashrafi","year":"2011","journal-title":"Taiwan J. Obstet. Gynecol."},{"key":"10.1016\/j.rbmo.2023.06.009_bib0003","doi-asserted-by":"crossref","first-page":"7635","DOI":"10.1007\/s00253-021-11531-4","article-title":"Microbial occurrence in liquid nitrogen storage tanks: a challenge for cryobanking?","volume":"105","author":"Bajerski","year":"2021","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.rbmo.2023.06.009_bib0004","doi-asserted-by":"crossref","first-page":"1976","DOI":"10.1093\/humrep\/den222","article-title":"A randomized controlled study of human Day 3 embryo cryopreservation by slow freezing or vitrification: vitrification is associated with higher survival, metabolism and blastocyst formation","volume":"23","author":"Balaban","year":"2008","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2023.06.009_bib0005","doi-asserted-by":"crossref","first-page":"R42","DOI":"10.1530\/RAF-22-0008","article-title":"Long-term preservation of germ cells and gonadal tissues at ambient temperatures","volume":"3","author":"Comizzoli","year":"2022","journal-title":"Reprod. Fertil."},{"key":"10.1016\/j.rbmo.2023.06.009_bib0006","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1016\/S0015-0282(00)00518-5","article-title":"Blastocyst score affects implantation and pregnancy outcome: towards a single blastocyst transfer","volume":"73","author":"Gardner","year":"2000","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2023.06.009_bib0007","article-title":"Long-Term Storage Does Not Affect the Expression Profiles of mRNA and Long Non-Coding RNA in Vitrified-Warmed Human Embryos","volume":"12","author":"Li","year":"2021","journal-title":"Front Genet."},{"key":"10.1016\/j.rbmo.2023.06.009_bib0008","first-page":"1","article-title":"The effect of storage time after vitrification on pregnancy and neonatal outcomes among 24 698 patients following the first embryo transfer cycles","author":"Li","year":"2020","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2023.06.009_bib0009","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1080\/09513590.2016.1207166","article-title":"Influence of storage time on vitrified human cleavage-stage embryos froze in open system","volume":"33","author":"Li","year":"2017","journal-title":"Gynecol. Endocrinol."},{"key":"10.1016\/j.rbmo.2023.06.009_bib0010","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/978-1-4939-6828-2_11","article-title":"Chapter 11 Human Embryo Vitrification","volume":"1568","author":"Liebermann","year":"2017","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.rbmo.2023.06.009_bib0011","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.cryobiol.2021.09.003","article-title":"Does longer storage of blastocysts with equal grades in a cryopreserved state affect the perinatal outcomes?","volume":"103","author":"Lin","year":"2021","journal-title":"Cryobiology"},{"key":"10.1016\/j.rbmo.2023.06.009_bib0012","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1007\/s10815-014-0197-0","article-title":"The safety of long-term cryopreservation on slow-frozen early cleavage human embryos","volume":"31","author":"Liu","year":"2014","journal-title":"J. Assist. Reprod. Genet."},{"key":"10.1016\/j.rbmo.2023.06.009_bib0013","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1055\/a-1326-1830","article-title":"Storage Time of Cryopreserved Embryos and Pregnancy Outcomes: A Dose-Response Meta-Analysis","volume":"81","author":"Ma","year":"2021","journal-title":"Geburtshilfe Frauenheilkd"},{"key":"10.1016\/j.rbmo.2023.06.009_bib0014","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cryobiol.2010.10.159","article-title":"Survival of mouse oocytes after being cooled in a vitrification solution to -196\u00b0C at 95\u00b0 to 70,000\u00b0C\/min and warmed at 610\u00b0 to 118,000\u00b0C\/min: A new paradigm for cryopreservation by vitrification","volume":"62","author":"Mazur","year":"2011","journal-title":"Cryobiology"},{"key":"10.1016\/j.rbmo.2023.06.009_bib0015","article-title":"[Expert consensus on human embryo morphological assessment: cleavage-stage embryos and blastocysts grading criteria]","volume":"42","author":"Medicine","year":"2022","journal-title":"Chin. J. Reprod. Contracep."},{"key":"10.1016\/j.rbmo.2023.06.009_bib0016","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.fertnstert.2019.12.009","article-title":"Vitrification of the human embryo: a more efficient and safer in vitro fertilization treatment","volume":"113","author":"Nagy","year":"2020","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2023.06.009_bib0017","doi-asserted-by":"crossref","first-page":"2632","DOI":"10.1093\/humrep\/deaa238","article-title":"The effect of cryostorage duration on vitrified embryos: has vitrification suddenly become unsafe?","volume":"35","author":"Parmegiani","year":"2020","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2023.06.009_bib0018","first-page":"139","article-title":"Oocyte, embryo and blastocyst cryopreservation in ART: systematic review and meta-analysis comparing slow-freezing versus vitrification to produce evidence for the development of global guidance","volume":"23","author":"Rienzi","year":"2017","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.rbmo.2023.06.009_bib0019","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.fertnstert.2008.09.084","article-title":"Does storage time influence postthaw survival and pregnancy outcome? An analysis of 11,768 cryopreserved human embryos","volume":"93","author":"Riggs","year":"2010","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2023.06.009_bib0020","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.theriogenology.2014.04.003","article-title":"Implications of storage and handling conditions on glass transition and potential devitrification of oocytes and embryos","volume":"82","author":"Sansinena","year":"2014","journal-title":"Theriogenology"},{"key":"10.1016\/j.rbmo.2023.06.009_bib0021","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1038\/305707a0","article-title":"Human pregnancy following cryopreservation, thawing and transfer of an eight-cell embryo","volume":"305","author":"Trounson","year":"1983","journal-title":"Nature"},{"key":"10.1016\/j.rbmo.2023.06.009_bib0022","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/j.rbmo.2018.03.008","article-title":"Cryostorage duration does not affect pregnancy and neonatal outcomes: a retrospective single-centre cohort study of vitrified-warmed blastocysts","volume":"36","author":"Ueno","year":"2018","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.rbmo.2023.06.009_bib0023","doi-asserted-by":"crossref","first-page":"2101","DOI":"10.1093\/humrep\/det107","article-title":"Lower intracellular concentration of cryoprotectants after vitrification than after slow freezing despite exposure to higher concentration of cryoprotectant solutions","volume":"28","author":"Vanderzwalmen","year":"2013","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2023.06.009_bib0024","doi-asserted-by":"crossref","first-page":"2950","DOI":"10.1093\/humrep\/det361","article-title":"The time aspect in storing vitrified blastocysts: its impact on survival rate, implantation potential and babies born","volume":"28","author":"Wirleitner","year":"2013","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2023.06.009_bib0025","first-page":"c22","article-title":"ART in Europe, 2018: results generated from European registries by ESHRE","volume":"2022","author":"Wyns","year":"2022","journal-title":"Hum. Reprod. Open."},{"key":"10.1016\/j.rbmo.2023.06.009_bib0026","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.fertnstert.2021.03.036","article-title":"Impact of oral antibiotic treatment for chronic endometritis on pregnancy outcomes in the following frozen-thawed embryo transfer cycles of infertile women: a cohort study of 640 embryo transfer cycles","volume":"116","author":"Xiong","year":"2021","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2023.06.009_bib0027","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1093\/humrep\/dey350","article-title":"What was the fate of human embryos following long-term cryopreservation (>\/= 12 years) and frozen embryo transfer?","volume":"34","author":"Yuan","year":"2019","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2023.06.009_bib0028","first-page":"1015","article-title":"[Annual report on assisted reproductive technology of Chinese Society of Reproductive Medicine in 2019]","volume":"31","author":"Zhang","year":"2022","journal-title":"J. Repord. Med."},{"key":"10.1016\/j.rbmo.2023.06.009_bib0029","article-title":"Prolonged Cryopreservation Negatively Affects Embryo Transfer Outcomes Following the Elective Freeze-All Strategy: A Multicenter Retrospective Study","volume":"12","author":"Zhang","year":"2021","journal-title":"Front Endocrinol (Lausanne)"}],"container-title":["Reproductive BioMedicine Online"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1472648323003504?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1472648323003504?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T08:25:44Z","timestamp":1761467144000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1472648323003504"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":29,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["S1472648323003504"],"URL":"https:\/\/doi.org\/10.1016\/j.rbmo.2023.06.009","relation":{},"ISSN":["1472-6483"],"issn-type":[{"value":"1472-6483","type":"print"}],"subject":[],"published":{"date-parts":[[2023,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Storage time does not influence pregnancy and neonatal outcomes for first single vitrified high-quality blastocyst transfer cycle","name":"articletitle","label":"Article Title"},{"value":"Reproductive BioMedicine Online","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rbmo.2023.06.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"103254"}}