{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T18:45:10Z","timestamp":1790448310114,"version":"4.1.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,7]],"date-time":"2025-08-07T00:00:00Z","timestamp":1754524800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100032305","name":"Asociaci\u00f3n Espa\u00f1ola de Cirujanos","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100032305","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","rbmojournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Reproductive BioMedicine Online"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.rbmo.2025.105209","type":"journal-article","created":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T23:25:27Z","timestamp":1754954727000},"page":"105209","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Does total motile sperm count predict embryo quality and ICSI success in young normal-weight women? A retrospective multicentre study"],"prefix":"10.1016","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8311-9095","authenticated-orcid":false,"given":"Andrea","family":"Crafa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rossella","family":"Cannarella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Navarro-Gomezlechon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa M","family":"Pacheco-Rend\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosita A","family":"Condorelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandro","family":"La Vignera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aldo E","family":"Calogero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicol\u00e1s","family":"Garrido","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.rbmo.2025.105209_bib0001","doi-asserted-by":"crossref","first-page":"1897","DOI":"10.1007\/s10815-018-1256-8","article-title":"Abnormal sperm concentration and motility as well as advanced paternal age compromise early embryonic development but not pregnancy outcomes: a retrospective study of 1266 ICSI cycles","volume":"35","author":"Bartolacci","year":"2018","journal-title":"J. Assist. Reprod. Genet."},{"key":"10.1016\/j.rbmo.2025.105209_bib0002","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.fertnstert.2006.11.162","article-title":"Obesity and poor reproductive outcome: the potential role of the endometrium","volume":"88","author":"Bellver","year":"2007","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2025.105209_bib0003","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1111\/andr.12199","article-title":"Total motile sperm count has a superior predictive value over the WHO 2010 cut-off values for the outcomes of intracytoplasmic sperm injection cycles","volume":"4","author":"Borges","year":"2016","journal-title":"Andrology"},{"key":"10.1016\/j.rbmo.2025.105209_bib0004","doi-asserted-by":"crossref","first-page":"796","DOI":"10.5534\/wjmh.220253","article-title":"Is It Time for andrology and endocrinology professionals in assisted reproduction centers?","volume":"41","author":"Cannarella","year":"2023","journal-title":"World J. Mens Health."},{"key":"10.1016\/j.rbmo.2025.105209_bib0005","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1515\/hmbci-2020-0089","article-title":"The outcome of intra-cytoplasmic sperm injection (ICSI): do the sperm concentration and motility matter?","volume":"42","author":"Chua","year":"2021","journal-title":"Horm. Mol. Biol. Clin. Investig."},{"key":"10.1016\/j.rbmo.2025.105209_bib0006","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1016\/j.fertnstert.2015.08.020","article-title":"Six years\u2019 experience in ovum donation using vitrified oocytes: report of cumulative outcomes, impact of storage time, and development of a predictive model for oocyte survival rate","volume":"104","author":"Cobo","year":"2015","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2025.105209_bib0007","doi-asserted-by":"crossref","first-page":"2239","DOI":"10.1093\/humrep\/deq146","article-title":"Use of cryo-banked oocytes in an ovum donation programme: a prospective, randomized, controlled, clinical trial","volume":"25","author":"Cobo","year":"2010","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2025.105209_bib0008","article-title":"The association of impaired semen quality and pregnancy rates in assisted reproduction technology cycles: systematic review and meta-analysis","volume":"54","author":"Del Giudice","year":"2022","journal-title":"Andrologia. 2022"},{"key":"10.1016\/j.rbmo.2025.105209_bib0009","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1111\/andr.12551","article-title":"High sperm DNA fragmentation delays human embryo kinetics when oocytes from young and healthy donors are microinjected","volume":"6","author":"Esbert","year":"2018","journal-title":"Andrology"},{"key":"10.1016\/j.rbmo.2025.105209_bib0010","doi-asserted-by":"crossref","first-page":"2062","DOI":"10.1093\/humrep\/dead184","article-title":"Good practice recommendations on add-ons in reproductive medicine","volume":"38","author":"Lundin","year":"2023","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2025.105209_bib0011","doi-asserted-by":"crossref","first-page":"2321","DOI":"10.1093\/humrep\/dead197","article-title":"ART in Europe, 2019: results generated from European registries by ESHRE","volume":"38","author":"Smeenk","year":"2023","journal-title":"Hum. Reprod"},{"key":"10.1016\/j.rbmo.2025.105209_bib0012","first-page":"hoac022","article-title":"ART in Europe, 2018: results generated from European registries by ESHRE","author":"Wyns","year":"2022","journal-title":"Hum Reprod Open. 2022"},{"key":"10.1016\/j.rbmo.2025.105209_bib0013","first-page":"hoab026","article-title":"ART in Europe, 2017: results generated from European registries by ESHRE","author":"Wyns","year":"2021","journal-title":"Hum. Reprod. Open. 2021"},{"key":"10.1016\/j.rbmo.2025.105209_bib0014","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1093\/humrep\/dev058","article-title":"Total motile sperm count: a better indicator for the severity of male factor infertility than the WHO sperm classification system","volume":"30","author":"Hamilton","year":"2015","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2025.105209_bib0015","first-page":"1443","article-title":"Infertility affects 1 in 6 people globally","volume":"329","author":"Harris","year":"2023","journal-title":"JAMA"},{"key":"10.1016\/j.rbmo.2025.105209_bib0016","first-page":"205","article-title":"Embryo quality and implantation rates are not influenced by total motile count values in an ICSI programme: a novel point of view","volume":"3","author":"Hershko-Klement","year":"2012","journal-title":"Int. J. Mol. Epidemiol. Genet."},{"key":"10.1016\/j.rbmo.2025.105209_bib0017","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1093\/humupd\/dmv016","article-title":"Infertility around the globe: new thinking on gender, reproductive technologies and global movements in the 21st century","volume":"21","author":"Inhorn","year":"2015","journal-title":"Hum. Reprod. Update."},{"key":"10.1016\/j.rbmo.2025.105209_bib0018","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1111\/andr.12908","article-title":"Relationship between male age, semen parameters and assisted reproductive technology outcomes","volume":"9","author":"Kasman","year":"2021","journal-title":"Andrology"},{"key":"10.1016\/j.rbmo.2025.105209_bib0019","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1016\/j.fertnstert.2021.01.014","article-title":"Clarifying the relationship between total motile sperm counts and intrauterine insemination pregnancy rates","volume":"115","author":"Muthigi","year":"2021","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2025.105209_bib0020","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.rbmo.2013.10.023","article-title":"Semen quality and prediction of IUI success in male subfertility: a systematic review","volume":"28","author":"Ombelet","year":"2014","journal-title":"Reprod. Biomed. Online."},{"key":"10.1016\/j.rbmo.2025.105209_bib0021","series-title":"R: A Language and Environment for Statistical Computing","year":"2024"},{"key":"10.1016\/j.rbmo.2025.105209_bib0022","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/S0015-0282(02)03178-3","article-title":"Use of the total motile sperm count to predict total fertilization failure in in vitro fertilization","volume":"78","author":"Repping","year":"2002","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2025.105209_bib0023","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1016\/j.fertnstert.2014.09.001","article-title":"Removal of annexin V-positive sperm cells for intracytoplasmic sperm injection in ovum donation cycles does not improve reproductive outcome: a controlled and randomized trial in unselected males","volume":"102","author":"Romany","year":"2014","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2025.105209_bib0024","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1111\/andr.13323","article-title":"Which sperm parameter limits could really guide the clinical decision in assisted reproduction?","volume":"11","author":"Santi","year":"2023","journal-title":"Andrology"},{"key":"10.1016\/j.rbmo.2025.105209_bib0025","doi-asserted-by":"crossref","DOI":"10.1111\/and.14211","article-title":"Early and late paternal contribution to cell division of embryos in a time-lapse imaging incubation system","volume":"53","author":"Setti","year":"2021","journal-title":"Andrologia"},{"key":"10.1016\/j.rbmo.2025.105209_bib0026","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1016\/S0015-0282(16)42976-6","article-title":"Relation between indices of semen analysis and pregnancy rate in infertile couples","volume":"28","author":"Smith","year":"1977","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2025.105209_bib0027","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/s40738-020-00092-1","article-title":"Predictive factors for intrauterine insemination outcomes: a review","volume":"6","author":"Starosta","year":"2020","journal-title":"Fertil. Res. Pract."},{"key":"10.1016\/j.rbmo.2025.105209_bib0028","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1016\/j.fertnstert.2004.01.042","article-title":"Performance of the postwash total motile sperm count as a predictor of pregnancy at the time of intrauterine insemination: a meta-analysis","volume":"82","author":"Van Weert","year":"2004","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2025.105209_bib0029","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1111\/andr.13123","article-title":"Are sperm parameters able to predict the success of assisted reproductive technology? A retrospective analysis of over 22,000 assisted reproductive technology cycles","volume":"10","author":"Villani","year":"2022","journal-title":"Andrology"},{"key":"10.1016\/j.rbmo.2025.105209_bib0030","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1007\/s43032-021-00801-1","article-title":"Male age and progressive sperm motility are critical factors affecting embryological and clinical outcomes in oocyte donor ICSI cycles","volume":"29","author":"Vogiatzi","year":"2022","journal-title":"Reprod. Sci."},{"key":"10.1016\/j.rbmo.2025.105209_bib0031","series-title":"1999 WHO Laboratory Manual for the Examination and Processing of Human Semen","year":"1999"},{"key":"10.1016\/j.rbmo.2025.105209_bib0032","series-title":"2010 WHO Laboratory Manual for the Examination and Processing of Human Semen","year":"2010"},{"key":"10.1016\/j.rbmo.2025.105209_bib0033","series-title":"2021 WHO Laboratory Manual for the Examination and Processing of Human Semen","year":"2021"},{"key":"10.1016\/j.rbmo.2025.105209_bib0034","unstructured":"World Health Organization. 2023. Infertility. Available on https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/infertility#:\u223c:text=Infertility%20is%20a%20disease%20of,on%20their%20families%20and%20communities. Last Access 29\/07\/2024."},{"key":"10.1016\/j.rbmo.2025.105209_bib0035","doi-asserted-by":"crossref","first-page":"454","DOI":"10.4103\/aja.aja_27_18","article-title":"Sperm origins and concentration do not impact the clinical outcomes in intracytoplasmic sperm injection cycles","volume":"20","author":"Yang","year":"2018","journal-title":"Asian J. Androl."},{"key":"10.1016\/j.rbmo.2025.105209_bib0036","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.repbio.2019.01.004","article-title":"Predictive factors for biochemical pregnancy in intracytoplasmic sperm injection cycles","volume":"19","author":"Zanetti","year":"2019","journal-title":"Reprod Biol"}],"container-title":["Reproductive BioMedicine Online"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S147264832500416X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S147264832500416X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T00:29:05Z","timestamp":1769214545000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S147264832500416X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":36,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["S147264832500416X"],"URL":"https:\/\/doi.org\/10.1016\/j.rbmo.2025.105209","relation":{},"ISSN":["1472-6483"],"issn-type":[{"value":"1472-6483","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Does total motile sperm count predict embryo quality and ICSI success in young normal-weight women? A retrospective multicentre study","name":"articletitle","label":"Article Title"},{"value":"Reproductive BioMedicine Online","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rbmo.2025.105209","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Ltd on behalf of Reproductive Healthcare Ltd.","name":"copyright","label":"Copyright"}],"article-number":"105209"}}