{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:13:27Z","timestamp":1788480807495,"version":"build-2803163510"},"reference-count":54,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81900287"],"award-info":[{"award-number":["81900287"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009110","name":"Natural Science Foundation of Xinjiang Uygur Autonomous Region","doi-asserted-by":"publisher","award":["2019D01A35"],"award-info":[{"award-number":["2019D01A35"]}],"id":[{"id":"10.13039\/100009110","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","rbmojournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Reproductive BioMedicine Online"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.rbmo.2026.105477","type":"journal-article","created":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T17:09:38Z","timestamp":1768583378000},"page":"105477","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["hsa-miR-375-3p in embryo culture medium exosomes as a preimplantation non-invasive biomarker for predicting live birth after IVF"],"prefix":"10.1016","volume":"53","author":[{"given":"Lingying","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mairepati","family":"Mahemuti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zulihumaer","family":"Yakupu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengyu","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusupujiang","family":"Maimaiti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Pang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojing","family":"Gan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiongzhen","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weidong","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeyidan","family":"Jiapaer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.rbmo.2026.105477_bib0001","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1093\/humrep\/der037","article-title":"The Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting","volume":"26","year":"2011","journal-title":"Hum Reprod."},{"issue":"30","key":"10.1016\/j.rbmo.2026.105477_bib0002","doi-asserted-by":"crossref","first-page":"8071","DOI":"10.1073\/pnas.1706908114","article-title":"tsRNA signatures in cancer","volume":"114","author":"Balatti","year":"2017","journal-title":"Proc Natl Acad Sci USA"},{"issue":"Database issue","key":"10.1016\/j.rbmo.2026.105477_bib0003","first-page":"D149","article-title":"The microRNA.org resource: targets and expression","volume":"36","author":"Betel","year":"2008","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.rbmo.2026.105477_bib0005","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/7193075","article-title":"The Impact of Biopsy on Human Embryo Developmental Potential during Preimplantation Genetic Diagnosis","volume":"2016","author":"Cimadomo","year":"2016","journal-title":"Biomed Res Int"},{"issue":"6","key":"10.1016\/j.rbmo.2026.105477_bib0006","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1210\/endrev\/bnac013","article-title":"Hippo Signaling in the Ovary: Emerging Roles in Development, Fertility, and Disease","volume":"43","author":"Clark","year":"2022","journal-title":"Endocr Rev"},{"issue":"4","key":"10.1016\/j.rbmo.2026.105477_bib0007","doi-asserted-by":"crossref","first-page":"hoac051","DOI":"10.1093\/hropen\/hoac051","article-title":"Infertility prevalence and the methods of estimation from 1990 to 2021: a systematic review and meta-analysis","volume":"2022","author":"Cox","year":"2022","journal-title":"Hum Reprod Open"},{"key":"10.1016\/j.rbmo.2026.105477_bib0008","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/j.fertnstert.2012.02.029","article-title":"Recurrent implantation failure: gamete and embryo factors","volume":"97","author":"Das","year":"2012","journal-title":"Fertility and sterility"},{"key":"10.1016\/j.rbmo.2026.105477_bib0009","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/S0015-0282(03)01200-7","article-title":"Embryo transfer quality and provider-specific pregnancy rates in IVF-ET","volume":"80","author":"Eisermann","year":"2003","journal-title":"Fertility and Sterility"},{"key":"10.1016\/j.rbmo.2026.105477_bib0010","doi-asserted-by":"crossref","first-page":"8689","DOI":"10.1038\/srep08689","article-title":"MiRNA-320 in the human follicular fluid is associated with embryo quality in vivo and affects mouse embryonic development in vitro","volume":"5","author":"Feng","year":"2015","journal-title":"Sci Rep"},{"key":"10.1016\/j.rbmo.2026.105477_bib0011","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/s40104-024-00997-7","article-title":"tRNAGlu-derived fragments from embryonic extracellular vesicles modulate bovine embryo hatching","volume":"15","author":"Fan","year":"2024","journal-title":"J Anim Sci Biotechnol"},{"issue":"17","key":"10.1016\/j.rbmo.2026.105477_bib0012","article-title":"TEAD4, YAP1 and WWTR1 prevent the premature onset of pluripotency prior to the 16-cell stage","volume":"146","author":"Frum","year":"2019","journal-title":"Development"},{"issue":"1","key":"10.1016\/j.rbmo.2026.105477_bib0013","doi-asserted-by":"crossref","first-page":"5210","DOI":"10.1038\/s41598-017-05549-w","article-title":"Secretome of in vitro cultured human embryos contains extracellular vesicles that are uptaken by the maternal side","volume":"7","author":"Giacomini","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.rbmo.2026.105477_bib0014","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2021.655882","article-title":"Murine Blastocysts Release Mature MicroRNAs Into Culture Media That Reflect Developmental Status","volume":"12","author":"Hawke","year":"2021","journal-title":"Front Genet"},{"key":"10.1016\/j.rbmo.2026.105477_bib0015","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1038\/s41421-019-0087-9","article-title":"Identification of small non-coding RNAs as sperm quality biomarkers for in vitro fertilization","volume":"5","author":"Hua","year":"2019","journal-title":"Cell Discov"},{"key":"10.1016\/j.rbmo.2026.105477_bib0016","doi-asserted-by":"crossref","first-page":"5751","DOI":"10.3390\/ijms24065751","article-title":"Non-Coding RNAs as Biomarkers for Embryo Quality and Pregnancy Outcomes: A Systematic Review and Meta-Analysis","volume":"24","author":"Huang","year":"2023","journal-title":"Int. J. Mol. Sci"},{"key":"10.1016\/j.rbmo.2026.105477_bib0017","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2021.103253","article-title":"PIWI-interacting RNA sequencing profiles in maternal plasma-derived exosomes reveal novel non-invasive prenatal biomarkers for the early diagnosis of nonsyndromic cleft lip and palate","volume":"65","author":"Jia","year":"2021","journal-title":"EBioMedicine"},{"issue":"19","key":"10.1016\/j.rbmo.2026.105477_bib0018","doi-asserted-by":"crossref","first-page":"4672","DOI":"10.3390\/molecules29194672","article-title":"Nanoparticle Tracking Analysis: An Effective Tool to Characterize Extracellular Vesicles","volume":"29","author":"Kowkabany","year":"2024","journal-title":"Molecules"},{"key":"10.1016\/j.rbmo.2026.105477_bib0019","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1186\/s12864-016-2697-z","article-title":"Germ cell and tumor associated piRNAs in the medaka and Xiphophorus melanoma models","volume":"17","author":"Kneitz","year":"2016","journal-title":"BMC Genomics"},{"key":"10.1016\/j.rbmo.2026.105477_bib0020","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.semcancer.2021.04.017","article-title":"Non-coding RNAs and lipids mediate the function of extracellular vesicles in cancer cross-talk","volume":"74","author":"Kotani","year":"2021","journal-title":"Semin Cancer Biol"},{"key":"10.1016\/j.rbmo.2026.105477_bib0021","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.bpobgyn.2020.07.004","article-title":"Non-invasive prenatal testing in the context of IVF and PGT-A","volume":"70","author":"Kimelman","year":"2021","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"issue":"1","key":"10.1016\/j.rbmo.2026.105477_bib0022","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1186\/s12958-021-00754-9","article-title":"Extracellular microRNAs: key players to explore the outcomes of in vitro fertilization","volume":"19","author":"Khan","year":"2021","journal-title":"Reprod Biol Endocrinol"},{"issue":"1","key":"10.1016\/j.rbmo.2026.105477_bib0023","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/s10735-024-10338-7","article-title":"Signaling pathway regulators in preimplantation embryos","volume":"56","author":"Karami","year":"2024","journal-title":"J Mol Histol"},{"issue":"14","key":"10.1016\/j.rbmo.2026.105477_bib0024","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.3390\/cells12141830","article-title":"A Role of PI3K\/Akt Signaling in Oocyte Maturation and Early Embryo Development","volume":"12","author":"Kalous","year":"2023","journal-title":"Cells"},{"issue":"1","key":"10.1016\/j.rbmo.2026.105477_bib0025","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1002\/pro.3711","article-title":"KEGG Mapper for inferring cellular functions from protein sequences","volume":"29","author":"Kanehisa","year":"2020","journal-title":"Protein Sci"},{"issue":"3","key":"10.1016\/j.rbmo.2026.105477_bib0026","doi-asserted-by":"crossref","first-page":"R25","DOI":"10.1186\/gb-2009-10-3-r25","article-title":"Ultrafast and memory-efficient alignment of short DNA sequences to the human genome","volume":"10","author":"Langmead","year":"2009","journal-title":"Genome Biol"},{"key":"10.1016\/j.rbmo.2026.105477_bib0027","doi-asserted-by":"crossref","first-page":"4051","DOI":"10.1038\/sj.emboj.7600385","article-title":"MicroRNA genes are transcribed by RNA polymerase II","volume":"23","author":"Lee","year":"2004","journal-title":"EMBO J"},{"issue":"9","key":"10.1016\/j.rbmo.2026.105477_bib0028","doi-asserted-by":"crossref","first-page":"2566","DOI":"10.3390\/cancers12092566","article-title":"Exosomes: A Source for New and Old Biomarkers in Cancer","volume":"12","author":"Logozzi","year":"2020","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.rbmo.2026.105477_bib0029","doi-asserted-by":"crossref","first-page":"D1241","DOI":"10.1093\/nar\/gkr828","article-title":"ExoCarta 2012: database of exosomal proteins, RNA and lipids","volume":"40","author":"Mathivanan","year":"2012","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.rbmo.2026.105477_bib0030","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1016\/j.jconrel.2022.12.027","article-title":"Hybrid exosomes, exosome-like nanovesicles and engineered exosomes for therapeutic applications","volume":"353","author":"Mondal","year":"2023","journal-title":"J Control Release"},{"issue":"271","key":"10.1016\/j.rbmo.2026.105477_bib0031","first-page":"cm1","article-title":"Wnt\/beta-catenin pathway","volume":"2005","author":"Moon","year":"2005","journal-title":"Sci STKE"},{"key":"10.1016\/j.rbmo.2026.105477_bib0033","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1093\/humrep\/16.2.259","article-title":"Cumulative conception and live birth rates in natural (unstimulated) IVF cycles","volume":"16","author":"Nargund","year":"2001","journal-title":"Human Reproduction"},{"key":"10.1016\/j.rbmo.2026.105477_bib0034","doi-asserted-by":"crossref","DOI":"10.1016\/j.repbio.2023.100847","article-title":"Expression of miRNA from spent pre-implantation embryos culture media","volume":"24","author":"Omes","year":"2024","journal-title":"Reprod Biol"},{"key":"10.1016\/j.rbmo.2026.105477_bib0035","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1111\/tog.12608","article-title":"Antenatal management of singleton pregnancies conceived using assisted reproductive technology","volume":"22","author":"Richardson","year":"2020","journal-title":"The Obstetrician & Gynaecologist"},{"key":"10.1016\/j.rbmo.2026.105477_bib0036","doi-asserted-by":"crossref","first-page":"847","DOI":"10.3390\/cancers13040847","article-title":"Regulation of Antitumor Immune Responses by Exosomes Derived from Tumor and Immune Cells","volume":"13","author":"Rinc\u00f3n-Riveros","year":"2021","journal-title":"Cancers (Basel)"},{"issue":"1","key":"10.1016\/j.rbmo.2026.105477_bib0037","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1186\/s12964-022-00959-4","article-title":"A review on exosomes application in clinical trials: perspective, questions, and challenges","volume":"20","author":"Rezaie","year":"2022","journal-title":"Cell Commun Signal"},{"issue":"5","key":"10.1016\/j.rbmo.2026.105477_bib0038","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1016\/j.fertnstert.2014.01.058","article-title":"Human embryos secrete microRNAs into culture media\u2013a potential biomarker for implantation","volume":"101","author":"Rosenbluth","year":"2014","journal-title":"Fertil Steril"},{"issue":"6","key":"10.1016\/j.rbmo.2026.105477_bib0039","first-page":"503","article-title":"Using Embryo Models to Understand the Development and Progression of Embryonic Lineages: A Focus on Primordial Germ Cell Development","volume":"213","author":"Rodriguez-Polo","year":"2024","journal-title":"Cells Tissues Organs"},{"issue":"2","key":"10.1016\/j.rbmo.2026.105477_bib0040","doi-asserted-by":"crossref","first-page":"637","DOI":"10.3390\/ijms22020637","article-title":"Human Embryo Models and Drug Discovery","volume":"22","author":"Rosner","year":"2021","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.rbmo.2026.105477_bib0041","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1093\/humrep\/del358","article-title":"Morphologic parameters of early cleavage-stage embryos that correlate with fetal development and delivery: prospective and applied data for increased pregnancy rates","volume":"22","author":"Scott","year":"2007","journal-title":"Human Reproduction"},{"key":"10.1016\/j.rbmo.2026.105477_bib0004","series-title":"DAVID: a web server for functional enrichment analysis and functional annotation of gene lists (2021 update)","author":"Sherman","year":"2022"},{"issue":"1","key":"10.1016\/j.rbmo.2026.105477_bib0043","article-title":"Bio-characteristics, tissue expression of miR-375 in hypothalamic-pituitary-ovarian axis and its regulation in reproduction-related diseases","volume":"14","author":"Sun","year":"2024","journal-title":"Sci Rep"},{"issue":"5","key":"10.1016\/j.rbmo.2026.105477_bib0044","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/j.molcel.2007.05.021","article-title":"The coming of age for Piwi proteins","volume":"26","author":"Seto","year":"2007","journal-title":"Mol Cell"},{"issue":"2","key":"10.1016\/j.rbmo.2026.105477_bib0045","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1002\/jcsm.13187","article-title":"tRNA-derived small RNA, 5\u2032tiRNA-Gly-CCC, promotes skeletal muscle regeneration through the inflammatory response","volume":"14","author":"Shen","year":"2023","journal-title":"J Cachexia Sarcopenia Muscle"},{"key":"10.1016\/j.rbmo.2026.105477_bib0046","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1038\/nri855","article-title":"Exosomes: composition, biogenesis and function","volume":"2","author":"Th\u00e9ry","year":"2002","journal-title":"Nat Rev Immunol"},{"issue":"12","key":"10.1016\/j.rbmo.2026.105477_bib0047","first-page":"1328","article-title":"Clinical Relevance of Secreted Small Noncoding RNAs in an Embryo Implantation Potential Prediction at Morula and Blastocyst Development Stages","volume":"11","author":"Timofeeva","year":"2021","journal-title":"Life (Basel)"},{"issue":"24","key":"10.1016\/j.rbmo.2026.105477_bib0048","doi-asserted-by":"crossref","first-page":"9399","DOI":"10.3390\/ijms21249399","article-title":"Small Noncoding RNA Signatures for Determining the Developmental Potential of an Embryo at the Morula Stage","volume":"21","author":"Timofeeva","year":"2020","journal-title":"Int J Mol Sci"},{"issue":"12","key":"10.1016\/j.rbmo.2026.105477_bib0049","doi-asserted-by":"crossref","first-page":"2912","DOI":"10.3390\/ijms20122912","article-title":"Cell-Free, Embryo-Specific sncRNA as a Molecular Biological Bridge between Patient Fertility and IVF Efficiency","volume":"20","author":"Timofeeva","year":"2019","journal-title":"Int J Mol Sci"},{"issue":"1","key":"10.1016\/j.rbmo.2026.105477_bib0050","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.tibs.2020.08.008","article-title":"Hippo Signaling in Embryogenesis and Development","volume":"46","author":"Wu","year":"2021","journal-title":"Trends Biochem Sci"},{"key":"10.1016\/j.rbmo.2026.105477_bib0051","doi-asserted-by":"crossref","first-page":"11907","DOI":"10.1073\/pnas.1613294113","article-title":"Noninvasive chromosome screening of human embryos by genome sequencing of embryo culture medium for in vitro fertilization","volume":"113","author":"Xu","year":"2016","journal-title":"Proc Natl Acad Sci USA"},{"issue":"1","key":"10.1016\/j.rbmo.2026.105477_bib0052","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1038\/s41392-023-01351-5","article-title":"tRF-Gln-CTG-026 ameliorates liver injury by alleviating global protein synthesis","volume":"8","author":"Ying","year":"2023","journal-title":"Signal Transduct Target Ther"},{"issue":"3","key":"10.1016\/j.rbmo.2026.105477_bib0053","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1007\/s00441-021-03530-8","article-title":"Cell fate determination and Hippo signaling pathway in preimplantation mouse embryo","volume":"386","author":"Yildirim","year":"2021","journal-title":"Cell Tissue Res"},{"issue":"4","key":"10.1016\/j.rbmo.2026.105477_bib0054","doi-asserted-by":"crossref","first-page":"891","DOI":"10.3390\/genes14040891","article-title":"WNT Co-Receptor LRP6 Is Critical for Zygotic Genome Activation and Embryonic Developmental Potential by Interacting with Oviductal Paracrine Ligand WNT2","volume":"14","author":"Yao","year":"2023","journal-title":"Genes (Basel)"},{"key":"10.1016\/j.rbmo.2026.105477_bib0055","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1159\/000373942","article-title":"Expression and potential role of microRNA-29b in mouse early embryo development","volume":"35","author":"Zhang","year":"2015","journal-title":"Cell Physiol Biochem"},{"issue":"1","key":"10.1016\/j.rbmo.2026.105477_bib0056","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1530\/JOE-20-0001","article-title":"miR-375 acts as a novel factor modulating pituitary prolactin synthesis through Rasd1 and Esr1","volume":"250","author":"Zhang","year":"2021","journal-title":"J Endocrinol"}],"container-title":["Reproductive BioMedicine Online"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1472648326000180?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1472648326000180?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T23:44:08Z","timestamp":1788479048000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1472648326000180"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":54,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["S1472648326000180"],"URL":"https:\/\/doi.org\/10.1016\/j.rbmo.2026.105477","relation":{},"ISSN":["1472-6483"],"issn-type":[{"value":"1472-6483","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"hsa-miR-375-3p in embryo culture medium exosomes as a preimplantation non-invasive biomarker for predicting live birth after IVF","name":"articletitle","label":"Article Title"},{"value":"Reproductive BioMedicine Online","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rbmo.2026.105477","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"105477"}}