{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T00:03:17Z","timestamp":1780617797596,"version":"3.54.1"},"reference-count":33,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","rbmojournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Reproductive BioMedicine Online"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.rbmo.2026.105478","type":"journal-article","created":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T16:46:04Z","timestamp":1769013964000},"page":"105478","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Gonadotrophin type and antral follicle count-adjusted follicular recruitment and oocyte yield in 4525 antagonist cycles"],"prefix":"10.1016","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8639-4877","authenticated-orcid":false,"given":"Lien","family":"Dhaenens","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"An-Sofie","family":"Rottiers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Vandierendonck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Hellebaut","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bj\u00f6rn","family":"Heindryckx","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly","family":"Tilleman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilse","family":"De Croo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chlo\u00eb","family":"De Roo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frauke","family":"Vanden Meerschaut","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominic","family":"Stoop","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.rbmo.2026.105478_bib0001","doi-asserted-by":"crossref","first-page":"579","DOI":"10.3389\/fendo.2019.00579","article-title":"FSH Requirements for Follicle Growth During Controlled Ovarian Stimulation","volume":"10","author":"Abbara","year":"2019","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.rbmo.2026.105478_bib0002","doi-asserted-by":"crossref","first-page":"589","DOI":"10.3389\/fendo.2018.00589","article-title":"Understanding Ovarian Hypo-Response to Exogenous Gonadotrophin in Ovarian Stimulation and Its New Proposed Marker\u2014The Follicle-To-Oocyte (FOI) Index","volume":"9","author":"Alviggi","year":"2018","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.rbmo.2026.105478_bib0003","doi-asserted-by":"crossref","first-page":"3217","DOI":"10.1093\/humrep\/del284","article-title":"Clinical outcome following stimulation with highly purified HMG or recombinant FSH in patients undergoing IVF: a randomized assessor-blind controlled trial","volume":"21","author":"Andersen","year":"2006","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2026.105478_bib0004","doi-asserted-by":"crossref","DOI":"10.1016\/j.fertnstert.2014.08.013","article-title":"Ovarian response to recombinant human follicle-stimulating hormone: a randomized, antim\u00fcllerian hormone\u2013stratified, dose\u2013response trial in women undergoing in vitro fertilization\/intracytoplasmic sperm injection","volume":"102","author":"Arce","year":"2014","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2026.105478_bib0005","doi-asserted-by":"crossref","first-page":"hoz008","DOI":"10.1093\/hropen\/hoz008","article-title":"Required amount of rFSH, HP-HMG and HP-FSH to reach a live birth: a systematic review and meta-analysis","volume":"2019","author":"Bordewijk","year":"2019","journal-title":"Hum. Reprod. Open"},{"key":"10.1016\/j.rbmo.2026.105478_bib0006","doi-asserted-by":"crossref","first-page":"2346","DOI":"10.1093\/humrep\/den220","article-title":"Highly purified HMG versus recombinant FSH in ovarian hyperstimulation with GnRH antagonists\u2014a randomized study","volume":"23","author":"Bosch","year":"2008","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2026.105478_bib0007","doi-asserted-by":"crossref","DOI":"10.1016\/j.fertnstert.2013.04.024","article-title":"Prediction of an excessive response in in vitro fertilization from patient characteristics and ovarian reserve tests and comparison in subgroups: an individual patient data meta-analysis","volume":"100","author":"Broer","year":"2013","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2026.105478_bib0008","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1186\/s12958-021-00768-3","volume":"19","author":"B\u00fchler","year":"2021","journal-title":"Reprod. Biol. Endocrinol."},{"key":"10.1016\/j.rbmo.2026.105478_bib0009","doi-asserted-by":"crossref","first-page":"859","DOI":"10.3390\/jcm11030859","article-title":"Women in Advanced Reproductive Age: Are the Follicular Output Rate, the Follicle-Oocyte Index and the Ovarian Sensitivity Index Predictors of Live Birth in an IVF Cycle?","volume":"11","author":"Carosso","year":"2022","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.rbmo.2026.105478_bib0010","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.3390\/jcm11082099","article-title":"Are There Ovarian Responsive Indexes That Predict Cumulative Live Birth Rates in Women over 39 Years?","volume":"11","author":"Cesarano","year":"2022","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.rbmo.2026.105478_bib0011","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.fertnstert.2011.12.016","article-title":"A randomized assessor-blind trial comparing highly purified HMG and recombinant FSH in a GnRH antagonist cycle with compulsory single-blastocyst transfer","volume":"97","author":"Devroey","year":"2012","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2026.105478_bib0012","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1093\/humrep\/deaf036","article-title":"Cumulative live birth rates of 31 478 untested embryos from 11 463 women challenge traditional recurrent implantation failure definitions","volume":"40","author":"Dhaenens","year":"2025","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2026.105478_bib0013","first-page":"71","article-title":"Manipulation of Human Ovarian Function: Physiological Concepts and Clinical Consequences*","volume":"18","author":"Fauser","year":"1997","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.rbmo.2026.105478_bib0014","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1093\/humupd\/dmn065","article-title":"Advances in recombinant DNA technology: corifollitropin alfa, a hybrid molecule with sustained follicle-stimulating activity and reduced injection frequency","volume":"15","author":"Fauser","year":"2009","journal-title":"Hum. Reprod. Updat."},{"key":"10.1016\/j.rbmo.2026.105478_bib0015","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1093\/humupd\/8.6.543","article-title":"The use of LH activity to drive folliculogenesis: exploring uncharted territories in ovulation induction","volume":"8","author":"Filicori","year":"2002","journal-title":"Hum. Reprod. Updat."},{"key":"10.1016\/j.rbmo.2026.105478_bib0016","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1093\/humrep\/der479","article-title":"Antral follicle responsiveness to follicle-stimulating hormone administration assessed by the Follicular Output RaTe (FORT) may predict in vitro fertilization-embryo transfer outcome","volume":"27","author":"Gallot","year":"2012","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2026.105478_bib0017","doi-asserted-by":"crossref","DOI":"10.1016\/j.rbmo.2025.104987","article-title":"A single dose of corifollitropin alfa is equipotent to a daily dose of 300 IU recombinant FSH regardless of ovarian reserve","volume":"51","author":"Garc\u00eda-Velasco","year":"2025","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.rbmo.2026.105478_bib0018","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1093\/humrep\/deq361","article-title":"Serum anti-M\u00fcllerian hormone levels are negatively related to Follicular Output RaTe (FORT) in normo-cycling women undergoing controlled ovarian hyperstimulation","volume":"26","author":"Genro","year":"2011","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2026.105478_bib0019","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.ejogrb.2018.11.002","article-title":"Comparison of the follicular output rate after controlled ovarian stimulation with daily recombinant follicle-stimulating hormone versus corifollitropin alfa","volume":"232","author":"Griesinger","year":"2019","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"key":"10.1016\/j.rbmo.2026.105478_bib0020","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1016\/j.rbmo.2017.03.004","article-title":"Follicular output rate can predict clinical pregnancy in women with unexplained infertility undergoing IVF\/ICSI: a prospective cohort study","volume":"34","author":"Hassan","year":"2017","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.rbmo.2026.105478_bib0021","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0303-7207(01)00469-5","article-title":"Gonadotropic control of ovarian follicular growth and development","volume":"179","author":"Hillier","year":"2001","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.rbmo.2026.105478_bib0022","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1093\/humrep\/dex208","article-title":"Efficacy and safety of follitropin alfa\/lutropin alfa in ART: a randomized controlled trial in poor ovarian responders","volume":"32","author":"Humaidan","year":"2017","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.rbmo.2026.105478_bib0023","doi-asserted-by":"crossref","first-page":"523","DOI":"10.2147\/IJWH.S403353","article-title":"Factors Influencing Follicular Output Rate and Follicle-to-Oocyte Index in POSEIDON-Defined Low-Prognosis Women in Vietnam: A Cross-Sectional Study","volume":"15","author":"Le","year":"2023","journal-title":"Int. J. Women\u2019s Heal."},{"key":"10.1016\/j.rbmo.2026.105478_bib0024","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1210\/er.2005-0015","article-title":"The Science behind 25 Years of Ovarian Stimulation for in Vitro Fertilization","volume":"27","author":"Macklon","year":"2006","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.rbmo.2026.105478_bib0025","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.rbmo.2010.11.005","article-title":"Anti-M\u00fcllerian hormone-based prediction model for a live birth in assisted reproduction","volume":"22","author":"Marca","year":"2011","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.rbmo.2026.105478_bib0026","article-title":"Controlled ovarian stimulation protocols for assisted reproduction: a network meta-analysis","volume":"2025","author":"Melo","year":"2025","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.rbmo.2026.105478_bib0027","article-title":"Association between the number of oocytes and cumulative live birth rate: A systematic review","volume":"87","author":"Neves","year":"2023","journal-title":"Best Pr. Res. Clin. Obstet. Gynaecol."},{"key":"10.1016\/j.rbmo.2026.105478_bib0028","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.fertnstert.2018.04.039","article-title":"Cumulative live birth rates according to the number of oocytes retrieved after the first ovarian stimulation for in vitro fertilization\/intracytoplasmic sperm injection: a multicenter multinational analysis including \u223c15,000 women","volume":"110","author":"Polyzos","year":"2018","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2026.105478_bib0029","doi-asserted-by":"crossref","DOI":"10.3389\/fmed.2021.702010","article-title":"Impact of Ovarian Yield\u2014Number of Total and Mature Oocytes Per Antral Follicular Count\u2014On Live Birth Occurrence After IVF Treatment","volume":"8","author":"Poulain","year":"2021","journal-title":"Front. Med."},{"key":"10.1016\/j.rbmo.2026.105478_bib0030","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s12958-024-01331-6","article-title":"The most appropriate indicators of successful ovarian stimulation","volume":"23","author":"Roque","year":"2025","journal-title":"Reprod. Biol. Endocrinol."},{"key":"10.1016\/j.rbmo.2026.105478_bib0031","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1093\/humupd\/dmq041","article-title":"Clinical outcomes in relation to the daily dose of recombinant follicle-stimulating hormone for ovarian stimulation in in vitro fertilization in presumed normal responders younger than 39 years: a meta-analysis","volume":"17","author":"Sterrenburg","year":"2011","journal-title":"Hum. Reprod. Updat."},{"key":"10.1016\/j.rbmo.2026.105478_bib0032","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.fertnstert.2024.11.005","article-title":"Luteinizing hormone\u2019s critical role in ovarian stimulation","volume":"123","author":"Toner","year":"2025","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.rbmo.2026.105478_bib0033","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1186\/1477-7827-8-137","article-title":"In vitro fertilisation with recombinant follicle stimulating hormone requires less IU usage compared with highly purified human menopausal gonadotrophin: results from a European retrospective observational chart review","volume":"8","author":"Trew","year":"2010","journal-title":"Reprod. Biol. Endocrinol."}],"container-title":["Reproductive BioMedicine Online"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1472648326000192?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1472648326000192?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T23:17:10Z","timestamp":1780615030000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1472648326000192"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":33,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["S1472648326000192"],"URL":"https:\/\/doi.org\/10.1016\/j.rbmo.2026.105478","relation":{},"ISSN":["1472-6483"],"issn-type":[{"value":"1472-6483","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Gonadotrophin type and antral follicle count-adjusted follicular recruitment and oocyte yield in 4525 antagonist cycles","name":"articletitle","label":"Article Title"},{"value":"Reproductive BioMedicine Online","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rbmo.2026.105478","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"105478"}}