{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T12:01:16Z","timestamp":1784980876392,"version":"3.55.0"},"reference-count":53,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003921","name":"Department of Health, Disability and Ageing","doi-asserted-by":"publisher","award":["4-I66SNMA"],"award-info":[{"award-number":["4-I66SNMA"]}],"id":[{"id":"10.13039\/501100003921","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100031334","name":"Endometriosis Australia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100031334","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100025520","name":"Medical Research Future Fund","doi-asserted-by":"publisher","award":["EPCD000020"],"award-info":[{"award-number":["EPCD000020"]}],"id":[{"id":"10.13039\/501100025520","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100025520","name":"Medical Research Future Fund","doi-asserted-by":"publisher","award":["MRF1199785"],"award-info":[{"award-number":["MRF1199785"]}],"id":[{"id":"10.13039\/501100025520","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","rbmojournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Reproductive BioMedicine Online"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.rbmo.2026.105500","type":"journal-article","created":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T17:09:11Z","timestamp":1769101751000},"page":"105500","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["A feasibility study to examine the link between lifestyle and environmental exposures and endometriotic phenotype"],"prefix":"10.1016","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7793-1933","authenticated-orcid":false,"given":"Blake","family":"Knapman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecilia","family":"Ng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brett","family":"McKinnon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana Meneses","family":"Gonzalez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akwasi","family":"Amoako","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anjali K.","family":"Henders","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Abbott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sally","family":"Mortlock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.rbmo.2026.105500_bib0001","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.jmig.2023.10.017","article-title":"Patient-Reported Outcome Measures Used in Randomized Controlled Trials Following Surgical Intervention for Endometriosis: A Structured Review from the AAGL Practice Guidelines Group","volume":"31","author":"Abbott","year":"2024","journal-title":"J Minim Invasive Gynecol"},{"issue":"5","key":"10.1016\/j.rbmo.2026.105500_bib0002","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1016\/j.fertnstert.2009.09.035","article-title":"Endometriosis fertility index: the new, validated endometriosis staging system","volume":"94","author":"Adamson","year":"2010","journal-title":"Fertil Steril"},{"issue":"3","key":"10.1016\/j.rbmo.2026.105500_bib0003","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1007\/s00439-020-02223-6","article-title":"Genetic analysis of endometriosis and depression identifies shared loci and implicates causal links with gastric mucosa abnormality","volume":"140","author":"Adewuyi","year":"2021","journal-title":"Hum Genet"},{"issue":"1","key":"10.1016\/j.rbmo.2026.105500_bib0004","first-page":"1","article-title":"Endometriosis - morphology, clinical presentations and molecular pathology","volume":"2","author":"Agarwal","year":"2010","journal-title":"J Lab Physicians"},{"issue":"5","key":"10.1016\/j.rbmo.2026.105500_bib0005","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/S0015-0282(97)81391-X","article-title":"Revised American Society for Reproductive Medicine classification of endometriosis: 1996","volume":"67","year":"1997","journal-title":"Fertil Steril"},{"issue":"6 Suppl","key":"10.1016\/j.rbmo.2026.105500_bib0006","doi-asserted-by":"crossref","first-page":"S43","DOI":"10.1210\/en.2005-1058","article-title":"Epigenetic transgenerational actions of endocrine disruptors","volume":"147","author":"Anway","year":"2006","journal-title":"Endocrinology"},{"issue":"3","key":"10.1016\/j.rbmo.2026.105500_bib0007","doi-asserted-by":"crossref","first-page":"C29","DOI":"10.1530\/RAF-22-0003","article-title":"Lessons from implementing the Australian National Action Plan for Endometriosis","volume":"3","author":"Armour","year":"2022","journal-title":"Reprod Fertil"},{"issue":"10","key":"10.1016\/j.rbmo.2026.105500_bib0008","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0223316","article-title":"The cost of illness and economic burden of endometriosis and chronic pelvic pain in Australia: A national online survey","volume":"14","author":"Armour","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.rbmo.2026.105500_bib0010","series-title":"Endometriosis","year":"2025"},{"key":"10.1016\/j.rbmo.2026.105500_bib0011","volume":"69","year":"2020"},{"key":"10.1016\/j.rbmo.2026.105500_bib0012","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2022.1020827","article-title":"Endometriosis-associated infertility: From pathophysiology to tailored treatment","volume":"13","author":"Bonavina","year":"2022","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"6","key":"10.1016\/j.rbmo.2026.105500_bib0013","first-page":"581","article-title":"Endometriosis, a modern syndrome","volume":"133","author":"Brosens","year":"2011","journal-title":"Indian J Med Res"},{"issue":"3","key":"10.1016\/j.rbmo.2026.105500_bib0014","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.fertnstert.2012.06.029","article-title":"Pathogenesis and pathophysiology of endometriosis","volume":"98","author":"Burney","year":"2012","journal-title":"Fertil Steril"},{"issue":"5","key":"10.1016\/j.rbmo.2026.105500_bib0015","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.jmig.2024.02.004","article-title":"A Call for New Theories on the Pathogenesis and Pathophysiology of Endometriosis","volume":"31","author":"Canis M","year":"2024","journal-title":"J Minim Invasive Gynecol"},{"issue":"7","key":"10.1016\/j.rbmo.2026.105500_bib0016","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1016\/j.jmig.2021.02.007","article-title":"Impact of Surgery for Deep Infiltrative Endometriosis before In Vitro Fertilization: A Systematic Review and Meta-analysis","volume":"28","author":"Casals","year":"2021","journal-title":"J Minim Invasive Gynecol"},{"key":"10.1016\/j.rbmo.2026.105500_bib0017","author":"Champely"},{"issue":"7","key":"10.1016\/j.rbmo.2026.105500_bib0018","doi-asserted-by":"crossref","first-page":"1512","DOI":"10.1093\/humrep\/deg254","article-title":"High plasma concentrations of di-(2-ethylhexyl)-phthalate in women with endometriosis","volume":"18","author":"Cobellis","year":"2003","journal-title":"Hum Reprod"},{"issue":"5","key":"10.1016\/j.rbmo.2026.105500_bib0019","doi-asserted-by":"crossref","DOI":"10.1016\/j.jogoh.2024.102759","article-title":"Endometriosis: Age at diagnosis and the severity of the disease","volume":"53","author":"Comptour","year":"2024","journal-title":"J Gynecol Obstet Hum Reprod"},{"issue":"23","key":"10.1016\/j.rbmo.2026.105500_bib0020","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1080\/15287394.2018.1547890","article-title":"Rural and urban differences in prenatal exposure to essential and toxic elements","volume":"81","author":"Cottrell","year":"2018","journal-title":"J Toxicol Environ Health A"},{"issue":"1","key":"10.1016\/j.rbmo.2026.105500_bib0021","doi-asserted-by":"crossref","first-page":"39","DOI":"10.5694\/mja12.11033","article-title":"A profile of body mass index in a large rural Victorian obstetric cohort","volume":"198","author":"Cunningham","year":"2013","journal-title":"Med J Aust"},{"issue":"8","key":"10.1016\/j.rbmo.2026.105500_bib0022","doi-asserted-by":"crossref","first-page":"547","DOI":"10.31128\/AJGP-10-22-6579","article-title":"Challenges in diagnosing and managing endometriosis in general practice: A Western Australian qualitative study","volume":"52","author":"Frayne","year":"2023","journal-title":"Aust J Gen Pract"},{"issue":"1","key":"10.1016\/j.rbmo.2026.105500_bib0023","doi-asserted-by":"crossref","first-page":"5543","DOI":"10.1038\/s41467-022-33222-y","article-title":"Author Correction: Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis","volume":"13","author":"Gallagher","year":"2022","journal-title":"Nat Commun"},{"issue":"3","key":"10.1016\/j.rbmo.2026.105500_bib0024","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.ajog.2018.11.123","article-title":"Depressive symptoms among women with endometriosis: a systematic review and meta-analysis","volume":"220","author":"Gambadauro","year":"2019","journal-title":"Am J Obstet Gynecol"},{"issue":"3","key":"10.1016\/j.rbmo.2026.105500_bib0025","doi-asserted-by":"crossref","first-page":"415.e411","DOI":"10.1016\/j.ajog.2020.02.033","article-title":"Psychiatric comorbidity among women with endometriosis: nationwide cohort study in Sweden","volume":"223","author":"Gao","year":"2020","journal-title":"Am J Obstet Gynecol"},{"issue":"5","key":"10.1016\/j.rbmo.2026.105500_bib0026","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajog.2023.07.033","article-title":"Associations between endometriosis and common symptoms: findings from the Australian Longitudinal Study on Women's Health","volume":"229","author":"Gete","year":"2023","journal-title":"Am J Obstet Gynecol"},{"issue":"1","key":"10.1016\/j.rbmo.2026.105500_bib0027","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/BF02705151","article-title":"Mechanisms for the environmental regulation of gene expression: ecological aspects of animal development","volume":"30","author":"Gilbert","year":"2005","journal-title":"J Biosci"},{"key":"10.1016\/j.rbmo.2026.105500_bib0028","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.reprotox.2016.07.011","article-title":"Environmental factors, epigenetics, and developmental origin of reproductive disorders","volume":"68","author":"Ho","year":"2017","journal-title":"Reproductive Toxicology"},{"issue":"2","key":"10.1016\/j.rbmo.2026.105500_bib0029","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1177\/2284026518773939","article-title":"The association of body mass index with endometriosis and disease severity in women with pain","volume":"10","author":"Holdsworth-Carson","year":"2018","journal-title":"Journal of Endometriosis and Pelvic Pain Disorders"},{"issue":"4","key":"10.1016\/j.rbmo.2026.105500_bib0030","doi-asserted-by":"crossref","first-page":"331","DOI":"10.52054\/FVVO.13.4.041","article-title":"What to choose and why to use - a critical review on the clinical relevance of rASRM, EFI and Enzian classifications of endometriosis","volume":"13","author":"Hudelist","year":"2021","journal-title":"Facts Views Vis Obgyn"},{"issue":"4","key":"10.1016\/j.rbmo.2026.105500_bib0031","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1210\/jc.2015-2873","article-title":"Female Reproductive Disorders, Diseases, and Costs of Exposure to Endocrine Disrupting Chemicals in the European Union","volume":"101","author":"Hunt","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"issue":"7","key":"10.1016\/j.rbmo.2026.105500_bib0032","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1289\/ehp.97105750","article-title":"Promotion of endometriosis in mice by polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls","volume":"105","author":"Johnson","year":"1997","journal-title":"Environ Health Perspect"},{"issue":"10","key":"10.1016\/j.rbmo.2026.105500_bib0033","article-title":"Protocol for the Endometriosis Research Queensland Study (ERQS): an integrated cohort study approach to improve diagnosis and stratify treatment","volume":"12","author":"Keisuke","year":"2022","journal-title":"BMJ Open"},{"key":"10.1016\/j.rbmo.2026.105500_bib0034","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/bs.apha.2021.03.008","article-title":"Endocrine disrupting chemicals and reproductive disorders in women, men, and animal models","volume":"92","author":"Laws","year":"2021","journal-title":"Adv Pharmacol"},{"issue":"29","key":"10.1016\/j.rbmo.2026.105500_bib0035","doi-asserted-by":"crossref","first-page":"46928","DOI":"10.18632\/oncotarget.14916","article-title":"Association between body mass index and endometriosis risk: a meta-analysis","volume":"8","author":"Liu","year":"2017","journal-title":"Oncotarget"},{"issue":"11","key":"10.1016\/j.rbmo.2026.105500_bib0036","doi-asserted-by":"crossref","first-page":"2243","DOI":"10.1093\/humrep\/dex291","article-title":"Endometriosis fertility index predicts live births following surgical resection of moderate and severe endometriosis","volume":"32","author":"Maheux-Lacroix","year":"2017","journal-title":"Hum Reprod"},{"issue":"9","key":"10.1016\/j.rbmo.2026.105500_bib0037","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1007\/s00439-023-02582-w","article-title":"Genomic characterisation of the overlap of endometriosis with 76 comorbidities identifies pleiotropic and causal mechanisms underlying disease risk","volume":"142","author":"McGrath","year":"2023","journal-title":"Hum Genet"},{"issue":"19","key":"10.1016\/j.rbmo.2026.105500_bib0038","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1056\/NEJMe1701700","article-title":"New Lessons about Endometriosis \u2014 Somatic Mutations and Disease Heterogeneity","volume":"376","author":"Montgomery","year":"2017","journal-title":"New England Journal of Medicine"},{"key":"10.1016\/j.rbmo.2026.105500_bib0039","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1016\/j.envres.2018.07.039","article-title":"Exposure to environment chemicals and its possible role in endocrine disruption of children from a rural area","volume":"167","author":"Nascimento","year":"2018","journal-title":"Environ Res"},{"issue":"2","key":"10.1016\/j.rbmo.2026.105500_bib0040","doi-asserted-by":"crossref","DOI":"10.1530\/RAF-23-0014","article-title":"Establishing the Australian National Endometriosis Clinical and Scientific Trials (NECST) Registry: A protocol paper","volume":"4","author":"Ng","year":"2023","journal-title":"Reprod Fertil"},{"issue":"5","key":"10.1016\/j.rbmo.2026.105500_bib0041","doi-asserted-by":"crossref","first-page":"577","DOI":"10.2217\/whe.15.41","article-title":"Genetics of Endometriosis","volume":"11","author":"Rahmioglu","year":"2015","journal-title":"Women's Health"},{"issue":"3","key":"10.1016\/j.rbmo.2026.105500_bib0042","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1038\/s41588-023-01323-z","article-title":"The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions","volume":"55","author":"Rahmioglu","year":"2023","journal-title":"Nature Genetics"},{"key":"10.1016\/j.rbmo.2026.105500_bib0043","series-title":"Australian clinical practice guideline for the diagnosis and management of endometriosis","year":"2021"},{"key":"10.1016\/j.rbmo.2026.105500_bib0044","series-title":"R: A language and environment for statistical computing","year":"2021"},{"issue":"4","key":"10.1016\/j.rbmo.2026.105500_bib0045","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1006\/faat.1993.1119","article-title":"Endometriosis in rhesus monkeys (Macaca mulatta) following chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin","volume":"21","author":"Rier","year":"1993","journal-title":"Fundam Appl Toxicol"},{"key":"10.1016\/j.rbmo.2026.105500_bib0046","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/978-3-030-51856-1_4","article-title":"Environmental Endocrine Disruptors and Endometriosis","volume":"232","author":"Rumph","year":"2020","journal-title":"Adv Anat Embryol Cell Biol"},{"issue":"2","key":"10.1016\/j.rbmo.2026.105500_bib0047","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1111\/obr.12334","article-title":"Predicting adult obesity from childhood obesity: a systematic review and meta-analysis","volume":"17","author":"Simmonds","year":"2016","journal-title":"Obes Rev"},{"issue":"4","key":"10.1016\/j.rbmo.2026.105500_bib0048","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/j.fertnstert.2016.06.034","article-title":"Endocrine disrupting chemicals and endometriosis","volume":"106","author":"Smarr","year":"2016","journal-title":"Fertil Steril"},{"issue":"4","key":"10.1016\/j.rbmo.2026.105500_bib0049","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1016\/j.fertnstert.2015.08.003","article-title":"Treatment of infertility associated with deep endometriosis: definition of therapeutic balances","volume":"104","author":"Somigliana","year":"2015","journal-title":"Fertil Steril"},{"issue":"4","key":"10.1016\/j.rbmo.2026.105500_bib0050","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/S0015-0282(98)00540-8","article-title":"Genetic influences on endometriosis in an Australian twin sample","volume":"71","author":"Treloar","year":"1999","journal-title":"Fertility and Sterility"},{"issue":"2","key":"10.1016\/j.rbmo.2026.105500_bib0051","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1003679","article-title":"Obesity and risk of female reproductive conditions: A Mendelian randomisation study","volume":"19","author":"Venkatesh","year":"2022","journal-title":"PLoS Med"},{"key":"10.1016\/j.rbmo.2026.105500_bib0052","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1186\/1472-6963-8-276","article-title":"Primary health care delivery models in rural and remote Australia: a systematic review","volume":"8","author":"Wakerman","year":"2008","journal-title":"BMC Health Serv Res"},{"key":"10.1016\/j.rbmo.2026.105500_bib0053","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.fertnstert.2025.09.024","article-title":"Is endometriosis a progressive disease? Examining age-related trends in disease severity and surgical complexity","volume":"125","author":"Yagur","year":"2025","journal-title":"Fertil Steril"},{"key":"10.1016\/j.rbmo.2026.105500_bib0054","article-title":"Combined Exposure to Multiple Endocrine Disruptors and Uterine Leiomyomata and Endometriosis in US Women","volume":"12","author":"Zhang","year":"2021","journal-title":"Front Endocrinol (Lausanne)"}],"container-title":["Reproductive BioMedicine Online"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1472648326000416?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1472648326000416?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T11:30:46Z","timestamp":1784979046000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1472648326000416"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":53,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["S1472648326000416"],"URL":"https:\/\/doi.org\/10.1016\/j.rbmo.2026.105500","relation":{},"ISSN":["1472-6483"],"issn-type":[{"value":"1472-6483","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A feasibility study to examine the link between lifestyle and environmental exposures and endometriotic phenotype","name":"articletitle","label":"Article Title"},{"value":"Reproductive BioMedicine Online","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rbmo.2026.105500","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Crown Copyright \u00a9 2026 Published by Elsevier Ltd on behalf of Reproductive Healthcare Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"105500"}}