{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T00:03:07Z","timestamp":1792195387475,"version":"4.4.0"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T00:00:00Z","timestamp":1733702400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Exploratory Research in Clinical and Social Pharmacy"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.rcsop.2024.100551","type":"journal-article","created":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T16:56:28Z","timestamp":1734022588000},"page":"100551","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["High alert medications off the radar: A systematic review"],"prefix":"10.1016","volume":"17","author":[{"given":"Michelle Santos","family":"Menezes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda","family":"Valen\u00e7a-Feitosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aline Santana","family":"G\u00f3es","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Millena Rakel dos","family":"Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laila Santana","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylmara Nayara Pereira dos","family":"Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Divaldo Pereira de","family":"Lyra Jr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfredo Dias","family":"de Oliveira Filho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.rcsop.2024.100551_bb0005","first-page":"1","article-title":"High-alert medication list for acute care settings updated for 2024. ISMP Medication Safety Alert!","volume":"29","author":"Institute for Safe Medication Practices (ISMP)","year":"2024","journal-title":"Acute Care"},{"key":"10.1016\/j.rcsop.2024.100551_bb0010","doi-asserted-by":"crossref","first-page":"3581","DOI":"10.34119\/bjhrv5n1-309","article-title":"Avalia\u00e7\u00e3o de prescri\u00e7\u00f5es de medicamentos potencialmente perigosos em um hospital do sudoeste da Bahia \/ Evaluation of prescriptions for potentially dangerous medicines in a hospital in southwest Bahia","volume":"5","author":"da Rodrigues","year":"2022","journal-title":"Brazil J Health Review"},{"key":"10.1016\/j.rcsop.2024.100551_bb0015","doi-asserted-by":"crossref","first-page":"11784","DOI":"10.1038\/s41598-021-91281-5","article-title":"Potential adverse drug events and its predictors among hospitalized patients at medical center in Ethiopia: a prospective observational study","volume":"11","author":"Sahilu","year":"2021","journal-title":"Sci Rep"},{"issue":"5","key":"10.1016\/j.rcsop.2024.100551_bb0020","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1345\/aph.1Q785","article-title":"Factors associated with reported preventable adverse drug events: a retrospective, case-control study","volume":"46","author":"Beckett","year":"2012","journal-title":"Ann Pharmacother"},{"issue":"47","key":"10.1016\/j.rcsop.2024.100551_bb0025","doi-asserted-by":"crossref","first-page":"42","DOI":"10.7748\/ns.2017.e10849","volume":"31","year":"2017","journal-title":"Nurs Stand"},{"issue":"1460","key":"10.1016\/j.rcsop.2024.100551_bb0030","first-page":"21","article-title":"Medication-related patient harm in New Zealand hospitals","volume":"130","author":"Robb","year":"2017","journal-title":"N Z Med J"},{"key":"10.1016\/j.rcsop.2024.100551_bb0035","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1111\/bcp.14119","article-title":"High-risk medicines associated with clinically relevant medication-related problems in UK hospitals: A prospective observational study","volume":"86","author":"Geeson","year":"2020","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.rcsop.2024.100551_bb0040","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1097\/PTS.0000000000000388","article-title":"Identifying High-alert Medications in a University Hospital by Applying Data From the Medication Error Reporting System","author":"Tyynismaa","year":"2021","journal-title":"J Patient Saf"},{"key":"10.1016\/j.rcsop.2024.100551_bb0045","article-title":"Harm Prevalence Due to Medication Errors Involving High-Alert Medications: A Systematic Review","volume":"30 Month","author":"Sodr\u00e9 Alves","year":"2024","journal-title":"J Patient Saf"},{"key":"10.1016\/j.rcsop.2024.100551_bb0050","author":"Institute for Safe Medication Practices"},{"key":"10.1016\/j.rcsop.2024.100551_bb0055","series-title":"ISMP List of High-Alert Medications in Acute Care Settings [Internet]","author":"Institute for Safe Medication Practices","year":"2024"},{"key":"10.1016\/j.rcsop.2024.100551_bb0060","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1080\/15360288.2017.1304493","article-title":"Doctor-related medication safety incidents on a specialist palliative medicine inpatient unit: a retrospective analysis of three years of voluntary reporting","volume":"31","author":"O\u2019Brien","year":"2017","journal-title":"J Pain Palliat Care Pharmacother"},{"issue":"12","key":"10.1016\/j.rcsop.2024.100551_bb0065","doi-asserted-by":"crossref","first-page":"871","DOI":"10.5005\/jp-journals-10071-24603","article-title":"Are \u201cHigh-alert Medication\u201d Used Safely in Intensive Care Units?","volume":"27","author":"Clerk","year":"2023","journal-title":"Indian J Crit Care Med"},{"issue":"1","key":"10.1016\/j.rcsop.2024.100551_bb0070","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1177\/1062860613482964","article-title":"Comparison of intensive care unit medication errors reported to the United States \u2018MedMarx and the United Kingdom\u2018s National Reporting and Learning System: a cross-sectional study","volume":"29","author":"Wahr","year":"2014","journal-title":"Am J Med Qual"},{"key":"10.1016\/j.rcsop.2024.100551_bb0075","doi-asserted-by":"crossref","first-page":"6788","DOI":"10.3390\/ijerph20186788","article-title":"Determining Medication Errors in an Adult Intensive Care Unit","volume":"20","author":"da Castro","year":"2023","journal-title":"Int J Environ Res Public Health"},{"key":"10.1016\/j.rcsop.2024.100551_bb0080","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1093\/intqhc\/mzu037","article-title":"Effects of patient-, environment- and medication-related factors on high-alert medication incidents","volume":"26","author":"Manias","year":"2014","journal-title":"International J Qual Health Care"},{"key":"10.1016\/j.rcsop.2024.100551_bb0085","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1345\/aph.1Q785","article-title":"Factors Associated with Reported Preventable Adverse Drug Events: A Retrospective, Case-Control Study","volume":"46","author":"Beckett","year":"2012","journal-title":"Ann Pharmacother"},{"key":"10.1016\/j.rcsop.2024.100551_bb0090","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1097\/PTS.0000000000000649","article-title":"Harm Prevalence Due to Medication Errors Involving High-Alert Medications: A Systematic Review","volume":"17","author":"Sodr\u00e9 Alves","year":"2021","journal-title":"J Patient Saf"},{"issue":"7","key":"10.1016\/j.rcsop.2024.100551_bb0095","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1000097","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"6","author":"Moher","year":"2009","journal-title":"PLoS Med"},{"key":"10.1016\/j.rcsop.2024.100551_bb0100","series-title":"Free from harm: accelerating patient safety improvement fifteen years after to err is human","first-page":"59","author":"National Patient Safety Foundation (NPSF)","year":"2015"},{"key":"10.1016\/j.rcsop.2024.100551_bb0105","series-title":"What is a medication error?","author":"National Coordinating Council for Medication Error Reporting and Prevention","year":"2015"},{"key":"10.1016\/j.rcsop.2024.100551_bb0110","doi-asserted-by":"crossref","first-page":"159","DOI":"10.2307\/2529310","article-title":"The measurement of observer agreement for categorical data","volume":"33","author":"Landis","year":"1977","journal-title":"Biometrics"},{"issue":"3","key":"10.1016\/j.rcsop.2024.100551_bb0115","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1590\/S0034-89102010000300021","article-title":"STROBE initiative: guidelines on reporting observational studies","volume":"44","author":"Malta","year":"2010","journal-title":"Rev Sa\u00fade P\u00fablica"},{"key":"10.1016\/j.rcsop.2024.100551_bb0120","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1007\/s001340101065","article-title":"Medication administration errors in adult patients in the ICU","volume":"27","author":"Calabrese","year":"2001","journal-title":"Intensive Care Med"},{"issue":"8","key":"10.1016\/j.rcsop.2024.100551_bb0125","doi-asserted-by":"crossref","first-page":"1694","DOI":"10.1097\/01.CCM.0000171609.91035.BD","article-title":"The critical care safety study: the incidence and nature of adverse events and serious medical errors in intensive care","volume":"33","author":"Rothschild","year":"2005","journal-title":"Crit Care Med"},{"key":"10.1016\/j.rcsop.2024.100551_bb0130","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1136\/bmjqs-2013-001828","article-title":"Characterising the complexity of medication safety using a human factors approach: an observational study in two intensive care units","volume":"23","author":"Carayon","year":"2014","journal-title":"BMJ Qual Saf"},{"issue":"6","key":"10.1016\/j.rcsop.2024.100551_bb0135","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.medin.2012.11.002","article-title":"Errores de medicaci\u00f3n en los servicios de Medicina Intensiva espa\u00f1oles","volume":"37","author":"Merino","year":"2013","journal-title":"Med Intensiva"},{"key":"10.1016\/j.rcsop.2024.100551_bb0140","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1111\/anae.12670","article-title":"An analysis of patient safety incidents associated with medications reported from critical care units in the North West of England between 2009 and 2012","volume":"69","author":"Thomas","year":"2014","journal-title":"Anaesthesia"},{"issue":"3","key":"10.1016\/j.rcsop.2024.100551_bb0145","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.enfi.2015.12.003","article-title":"An\u00e1lisis del registro de un Sistema de notification de incidents en una unidade de cuidados cr\u00edticos","volume":"27","author":"Murillo-P\u00e9rez","year":"2016","journal-title":"Enferm Intensiva"},{"key":"10.1016\/j.rcsop.2024.100551_bb0150","first-page":"31","article-title":"Evaluation of medication errors with implementation of electronic health record technology in the medical intensive care unit. Open Access Journal of","volume":"9","author":"Liao","year":"2017","journal-title":"Clin Trials"},{"issue":"2","key":"10.1016\/j.rcsop.2024.100551_bb0155","article-title":"Potentially Hazardous Drugs: Identfication of risks and error prevention barriers in intensive care","volume":"27","author":"Reis","year":"2018","journal-title":"Texto Contexto Enferm"},{"issue":"4","key":"10.1016\/j.rcsop.2024.100551_bb0160","first-page":"331","article-title":"Prevalence of medication-related incidents in an intensive care unit","volume":"28","author":"Azevedo","year":"2015","journal-title":"Acta Paulista de Enfermagem"},{"issue":"2","key":"10.1016\/j.rcsop.2024.100551_bb0165","article-title":"Nurses\u2019 experience about incidents related to medication administration in intensive care","volume":"8","author":"Costa","year":"2018","journal-title":"J Nurs health"},{"issue":"4","key":"10.1016\/j.rcsop.2024.100551_bb0170","article-title":"Assist\u00eancia segura ao paciente no preparo e administra\u00e7\u00e3o de medicamentos","volume":"38","author":"Rodriguez","year":"2017","journal-title":"Rev Gaucha Enferm"},{"issue":"5","key":"10.1016\/j.rcsop.2024.100551_bb0175","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1097\/NNR.0000000000000240","article-title":"Facilitated Nurse Medication - Related Event Reporting to Improve Medication Management Quality and Safety in Intensive Care Units","volume":"66","author":"Xu","year":"2017","journal-title":"Nurs Res"},{"issue":"4","key":"10.1016\/j.rcsop.2024.100551_bb0180","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1111\/ijpp.12243","article-title":"Impact of the introduction of a specialist critical care pharmacist on the level of pharmaceutical care provided to the critical care unit","volume":"24","author":"Richter","year":"2016","journal-title":"Int J Pharm Pract"},{"issue":"1","key":"10.1016\/j.rcsop.2024.100551_bb0185","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1186\/s12887-023-04333-2","article-title":"Medication errors related to high-alert medications in a paediatric university hospital - a cross-sectional study analysing error reporting system data","volume":"23","author":"Kuitunen","year":"2023","journal-title":"BMC Pediatr"},{"issue":"5","key":"10.1016\/j.rcsop.2024.100551_bb0190","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.jsps.2013.11.003","article-title":"Factors contributing to the identification and prevention of incorrect drug prescribing errors in outpatient setting","volume":"22","author":"Al-Khani","year":"2014","journal-title":"Saudi Pharm J"},{"issue":"1","key":"10.1016\/j.rcsop.2024.100551_bb0195","first-page":"27","article-title":"Avalia\u00e7\u00e3o das prescri\u00e7\u00f5es medicamentosas pedi\u00e1tricas de um hospital de ensino","volume":"3","author":"Soares","year":"2012","journal-title":"Rev Brasil de Farm Hospit e Servi de Sa\u00fade"},{"issue":"1","key":"10.1016\/j.rcsop.2024.100551_bb0200","first-page":"25","article-title":"Evaluation of perioperative medication errors and adverse drug events","volume":"124","author":"Nanji","year":"2016","journal-title":"J American Soc Anesthesiologists"},{"issue":"1","key":"10.1016\/j.rcsop.2024.100551_bb0205","first-page":"35","article-title":"Erros de medica\u00e7\u00e3o em adultos criticamente doentes: uma revis\u00e3o de evid\u00eancias de observa\u00e7\u00e3o direta","volume":"20","author":"Kiekkas","year":"2011","journal-title":"Sou J Crit Care"},{"key":"10.1016\/j.rcsop.2024.100551_bb0210","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.ccc.2006.02.005","article-title":"Principles and practices of medication safety in the ICU","volume":"22","author":"Kane-Gill","year":"2006","journal-title":"Crit Care Clin"},{"key":"10.1016\/j.rcsop.2024.100551_bb0215","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1007\/s40264-018-0756-x","article-title":"Evaluation of Harm Associated with High Dose-Range Clinical Decision Support Overrides in the Intensive Care Unit","volume":"42","author":"Wong","year":"2019","journal-title":"Drug Saf"},{"issue":"6","key":"10.1016\/j.rcsop.2024.100551_bb0220","doi-asserted-by":"crossref","DOI":"10.1590\/1982-0194201900092","article-title":"Error de administraci\u00f3n de medicamentos antiinfecciosos por omisi\u00f3n de dosis","volume":"32","author":"Castro","year":"2019","journal-title":"Acta paul enferm"},{"key":"10.1016\/j.rcsop.2024.100551_bb0225","doi-asserted-by":"crossref","DOI":"10.7748\/ns.2017.e10849","article-title":"Administering and monitoring high-alert medications in acute care","author":"Cajanding","year":"2017","journal-title":"Nurs Stand"},{"key":"10.1016\/j.rcsop.2024.100551_bb0230","first-page":"1","volume":"25, n. 1","author":"Muroi","year":"2016"},{"key":"10.1016\/j.rcsop.2024.100551_bb0235","series-title":"Seguran\u00e7a do paciente em unidade de terapia intensiva de acordo com a teoria de wanda horta","volume":"22, n.3","author":"Perao OF","year":"2017"},{"key":"10.1016\/j.rcsop.2024.100551_bb0240","series-title":"Comunica\u00e7\u00e3o no handoff na terapia intensiva","first-page":"01","volume":"22, 2","author":"Santos","year":"2018"},{"key":"10.1016\/j.rcsop.2024.100551_bb0245","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1111\/jep.13912","article-title":"A retrospective analysis of the factors associated with surgical checklist compliance using data from a local health unit in Italy, 2018\u20132021","volume":"29","author":"Rossi","year":"2023","journal-title":"J Eval Clin Pract"},{"issue":"1179\u201384","key":"10.1016\/j.rcsop.2024.100551_bb0250","first-page":"4","article-title":"The effect of a simple checklist on frequent pre -induction deficiencies","volume":"54","author":"Thomassen","year":"2010","journal-title":"Acta Anaesthesiol Scand"},{"key":"10.1016\/j.rcsop.2024.100551_bb0255","doi-asserted-by":"crossref","first-page":"2725","DOI":"10.1056\/NEJMoa061115","article-title":"An intervention to decrease catheter -related bloodstream infections in the ICU","volume":"355","author":"Pronovost","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1016\/j.rcsop.2024.100551_bb0260","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1111\/jocn.15184","article-title":"The introduction of a safety checklist in two UK hospital emergency departments: A qualitative study of implementation and staff use","volume":"29","author":"Stone","year":"2020","journal-title":"J Clin Nurs"},{"key":"10.1016\/j.rcsop.2024.100551_bib261","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1111\/jocn.15184","article-title":"The introduction of a safety checklist in two UK hospital emergency departments: A qualitative study of implementation and staff use","volume":"29","author":"Stone","year":"2020","journal-title":"Journal of Clinical Nursing"}],"container-title":["Exploratory Research in Clinical and Social Pharmacy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2667276624001483?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2667276624001483?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T21:52:53Z","timestamp":1741125173000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2667276624001483"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":53,"alternative-id":["S2667276624001483"],"URL":"https:\/\/doi.org\/10.1016\/j.rcsop.2024.100551","relation":{},"ISSN":["2667-2766"],"issn-type":[{"value":"2667-2766","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"High alert medications off the radar: A systematic review","name":"articletitle","label":"Article Title"},{"value":"Exploratory Research in Clinical and Social Pharmacy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rcsop.2024.100551","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"100551"}}