{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T11:40:56Z","timestamp":1760182856271,"version":"build-2065373602"},"reference-count":232,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T00:00:00Z","timestamp":1383264000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T00:00:00Z","timestamp":1383264000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Rheumatic Disease Clinics of North America"],"published-print":{"date-parts":[[2013,11]]},"DOI":"10.1016\/j.rdc.2013.05.005","type":"journal-article","created":{"date-parts":[[2013,7,13]],"date-time":"2013-07-13T16:01:04Z","timestamp":1373731264000},"page":"801-832","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Rheumatic Inflammatory Eye Diseases of Childhood"],"prefix":"10.1016","volume":"39","author":[{"given":"Andreas","family":"Reiff","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sibel","family":"Kadayifcilar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seza","family":"\u00d6zen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.rdc.2013.05.005_bib1","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1177\/112067219600600313","article-title":"Uveitis in children","volume":"6","author":"Pivetti-Pezzi","year":"1996","journal-title":"Eur J Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib2","series-title":"The molecular pathology of autoimmune diseases","first-page":"978","article-title":"Autoimmune diseases of the eye","author":"Gery","year":"2002"},{"issue":"8","key":"10.1016\/j.rdc.2013.05.005_bib3","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1007\/s11926-006-0042-2","article-title":"Ocular complication in childhood rheumatologic diseases: uveitis","volume":"6","author":"Reiff","year":"2006","journal-title":"Curr Rheumatol Rep"},{"issue":"3","key":"10.1016\/j.rdc.2013.05.005_bib4","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1007\/s11926-009-0031-3","article-title":"Ocular complication in child hood rheumatologic diseases: non uveitic disorders","volume":"11","author":"Reiff","year":"2009","journal-title":"Curr Rheumatol Rep"},{"issue":"5","key":"10.1016\/j.rdc.2013.05.005_bib5","first-page":"411","article-title":"Uveitis in juvenile idiopathic arthritis","volume":"69","author":"Heinz","year":"2010","journal-title":"Z\u00a0Rheumatol"},{"key":"10.1016\/j.rdc.2013.05.005_bib6","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/S0161-6420(96)30682-9","article-title":"Changing patterns in uveitis of childhood","volume":"103","author":"Tugal-Tutkun","year":"1996","journal-title":"Ophthalmology"},{"key":"10.1016\/j.rdc.2013.05.005_bib7","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/S0002-9394(03)00104-1","article-title":"Arthritis and uveitis in children: a pediatric rheumatology perspective","volume":"135","author":"Petty","year":"2003","journal-title":"Am J Ophthalmol"},{"issue":"1","key":"10.1016\/j.rdc.2013.05.005_bib8","doi-asserted-by":"crossref","first-page":"2","DOI":"10.3109\/09273940903348835","article-title":"Are the Standardization of the Uveitis Nomenclature (SUN) Working Group criteria for codifying the site of inflammation appropriate for all uveitis problems? Limitations of the SUN Working Group Classification","volume":"18","author":"Khairallah","year":"2010","journal-title":"Ocul Immunol Inflamm"},{"issue":"3","key":"10.1016\/j.rdc.2013.05.005_bib9","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.ajo.2005.03.057","article-title":"Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop","volume":"140","author":"Jabs","year":"2005","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib10","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/S0002-9394(02)02148-7","article-title":"Visual loss associated with pediatric uveitis in English primary and referral centers","volume":"135","author":"Edelsten","year":"2003","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib11","doi-asserted-by":"crossref","first-page":"497","DOI":"10.2165\/00003495-200565040-00005","article-title":"Management of sight-threatening uveitis: new therapeutic options","volume":"65","author":"Becker","year":"2005","journal-title":"Drugs"},{"key":"10.1016\/j.rdc.2013.05.005_bib12","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1016\/j.ophtha.2009.05.002","article-title":"Epidemiology and course of disease in childhood uveitis","volume":"116","author":"Smith","year":"2009","journal-title":"Ophthalmology"},{"key":"10.1016\/j.rdc.2013.05.005_bib13","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1136\/bjo.2004.050609","article-title":"Uveitis in children and adolescents","volume":"89","author":"BenEzra","year":"2005","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib14","doi-asserted-by":"crossref","first-page":"173","DOI":"10.4103\/0301-4738.31936","article-title":"Global variation and pattern changes in epidemiology of uveitis","volume":"55","author":"Rathinam","year":"2007","journal-title":"Indian J Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib15","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1080\/09286580802262821","article-title":"Demographic and clinical features of uveitis in tertiary centers in Turkey","volume":"15","author":"Kazokoglu","year":"2008","journal-title":"Ophthalmic Epidemiol"},{"key":"10.1016\/j.rdc.2013.05.005_bib16","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1034\/j.1600-0420.2000.078001084.x","article-title":"Uveitis in children: population-based study in Finland","volume":"78","author":"Paiv\u00f6nsalo-Hietanen","year":"2000","journal-title":"Acta Ophthalmol Scand"},{"key":"10.1016\/j.rdc.2013.05.005_bib17","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1080\/09273940802702561","article-title":"Uveitis in childhood: an Italian clinical and epidemiological study","volume":"17","author":"Paroli","year":"2009","journal-title":"Ocul Immunol Inflamm"},{"key":"10.1016\/j.rdc.2013.05.005_bib18","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/j.ophtha.2003.06.014","article-title":"Incidence and prevalence of uveitis in Northern California; the Northern California Epidemiology of Uveitis Study","volume":"111","author":"Gritz","year":"2004","journal-title":"Ophthalmology"},{"issue":"5","key":"10.1016\/j.rdc.2013.05.005_bib19","doi-asserted-by":"crossref","first-page":"315","DOI":"10.3109\/09273948.2012.710706","article-title":"Susceptibility genes and pharmacogenetics in ocular inflammatory disorders","volume":"20","author":"Liu","year":"2012","journal-title":"Ocul Immunol Inflamm"},{"issue":"9","key":"10.1016\/j.rdc.2013.05.005_bib20","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1016\/S0161-6420(90)32446-6","article-title":"HLA associations and ancestry in Vogt-Koyanagi-Harada disease and sympathetic ophthalmia","volume":"97","author":"Davis","year":"1990","journal-title":"Ophthalmology"},{"issue":"2","key":"10.1016\/j.rdc.2013.05.005_bib21","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1590\/S0004-27492012000200016","article-title":"Experimental models of autoimmune inflammatory ocular diseases","volume":"75","author":"Gasparin","year":"2012","journal-title":"Arq Bras Oftalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib22","doi-asserted-by":"crossref","first-page":"7086","DOI":"10.4049\/jimmunol.172.11.7086","article-title":"Type I collagen is the autoantigen in experimental anterior uveitis","volume":"172","author":"Bora","year":"2004","journal-title":"J\u00a0Immunol"},{"issue":"9","key":"10.1016\/j.rdc.2013.05.005_bib23","doi-asserted-by":"crossref","first-page":"3073","DOI":"10.1172\/JCI42440","article-title":"A\u00a0look at autoimmunity and inflammation in the eye","volume":"120","author":"Caspi","year":"2010","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.rdc.2013.05.005_bib24","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/S0021-5155(01)00369-0","article-title":"Differentiation of Th1 and Th2 cells in lymph nodes and spleens of mice during experimental autoimmune uveoretinitis","volume":"45","author":"Takeuchi","year":"2001","journal-title":"Jpn J Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib25","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1167\/iovs.09-3514","article-title":"Contribution of CD4+CD25+ T cells to the regression phase of experimental autoimmune uveoretinitis","volume":"51","author":"Sun","year":"2010","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"8","key":"10.1016\/j.rdc.2013.05.005_bib26","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1172\/JCI15155","article-title":"A\u00a0humanized model of experimental autoimmune uveitis in HLA class II transgenic mice","volume":"111","author":"Pennesi","year":"2003","journal-title":"J\u00a0Clin Invest"},{"issue":"4","key":"10.1016\/j.rdc.2013.05.005_bib27","doi-asserted-by":"crossref","first-page":"255","DOI":"10.3109\/09273948.2012.681830","article-title":"Treg lymphocytes in autoimmune uveitis","volume":"20","author":"Ruggieri","year":"2012","journal-title":"Ocul Immunol Inflamm"},{"key":"10.1016\/j.rdc.2013.05.005_bib28","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1159\/000055677","article-title":"Aqueous humor and serum tumor necrosis factor-alpha in clinical uveitis","volume":"33","author":"Lacomba","year":"2001","journal-title":"Ophthalmic Res"},{"key":"10.1016\/j.rdc.2013.05.005_bib29","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.ajo.2005.03.003","article-title":"Pathogenesis of macular edema with branch retinal vein occlusion and intraocular levels of vascular endothelial growth factor and interleukin-6","volume":"140","author":"Noma","year":"2005","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib30","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/0896-8411(90)90144-H","article-title":"Pathology of experimental autoimmune uveoretinitis in mice","volume":"3","author":"Chan","year":"1990","journal-title":"J\u00a0Autoimmun"},{"key":"10.1016\/j.rdc.2013.05.005_bib31","doi-asserted-by":"crossref","first-page":"169","DOI":"10.3109\/02713689008999438","article-title":"The mouse as a model of experimental autoimmune uveoretinitis (EAU)","volume":"9","author":"Caspi","year":"1990","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.rdc.2013.05.005_bib32","first-page":"3177","article-title":"Macrophages and dendritic cells in IRBP- induced experimental autoimmune uveoretinitis in B10.RIII mice","volume":"40","author":"Jiang","year":"1999","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"8","key":"10.1016\/j.rdc.2013.05.005_bib33","first-page":"4668","article-title":"CXCR4 but not CXCR7 is mainly implicated in ocular leukocyte trafficking during ovalbumin-induced acute uveitis","volume":"53","author":"Zhang","year":"2012","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.rdc.2013.05.005_bib34","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.preteyeres.2012.10.002","article-title":"Immunological homeostasis of the eye","volume":"33","author":"Mochizuki","year":"2013","journal-title":"Prog Retin Eye Res"},{"key":"10.1016\/j.rdc.2013.05.005_bib35","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1001\/archopht.118.6.768","article-title":"Aqueous and serum interferon gamma, interleukin (IL) 2, IL-4, and IL-10 in patients with uveitis","volume":"118","author":"Lacomba","year":"2000","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib36","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1016\/S0161-6420(98)99035-2","article-title":"High levels of interleukin-12 in the aqueous humor and vitreous of patients with uveitis","volume":"105","author":"El-Shabrawi","year":"1998","journal-title":"Ophthalmology"},{"key":"10.1016\/j.rdc.2013.05.005_bib37","first-page":"3376","article-title":"Chemoattractant and neutrophil degranulation activities related to interleukin-8 in vitreous fluid in uveitis and vitreo-retinal disorders","volume":"34","author":"de Boer","year":"1993","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.rdc.2013.05.005_bib38","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1080\/092739490500282","article-title":"Elevated levels of interleukin 6 in the vitreous fluid of patients with pars planitis and posterior uveitis: the Massachusetts eye & ear experience and review of previous studies","volume":"12","author":"Perez","year":"2004","journal-title":"Ocul Immunol Inflamm"},{"issue":"Suppl","key":"10.1016\/j.rdc.2013.05.005_bib39","doi-asserted-by":"crossref","first-page":"187","DOI":"10.3109\/02713689208999531","article-title":"Cytokines in human intraocular inflammation","volume":"11","author":"Franks","year":"1992","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.rdc.2013.05.005_bib40","first-page":"1444","article-title":"Identification of the lymphokines, interferon-gamma and interleukin-2, in inflammatory eye diseases","volume":"29","author":"Hooks","year":"1988","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.rdc.2013.05.005_bib41","first-page":"33","article-title":"Dominance of activated T cells and interleukin-6 in aqueous humor in Vogt-Koyanagi-Harada disease","volume":"35","author":"Norose","year":"1994","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.rdc.2013.05.005_bib42","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1097\/01.iio.0000155903.87679.c2","article-title":"Uveitis in children","volume":"45","author":"Zierhut","year":"2005","journal-title":"Int Ophthalmol Clin"},{"key":"10.1016\/j.rdc.2013.05.005_bib43","first-page":"443","article-title":"Optical coherence tomography characteristics of eyes with acute anterior uveitis","volume":"900","author":"Shulman","year":"2012","journal-title":"Methods Mol Biol"},{"key":"10.1016\/j.rdc.2013.05.005_bib44","first-page":"313120","article-title":"Application of anterior segment optical coherence tomography in pediatric ophthalmology","volume":"2012","author":"Cauduro","year":"2012","journal-title":"J\u00a0Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib45","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1136\/bjo.2007.120675","article-title":"Maculopathy in uveitis of juvenile idiopathic arthritis: an optical coherence tomography study","volume":"92","author":"Ducos de Lahitte","year":"2008","journal-title":"Br J Ophthalmol"},{"issue":"43","key":"10.1016\/j.rdc.2013.05.005_bib46","first-page":"36012","article-title":"Corneal biomechanical properties in patients with recurrent anterior uveitis","volume":"287","author":"JTuran-Vural","year":"2012","journal-title":"Biol Chem"},{"issue":"2","key":"10.1016\/j.rdc.2013.05.005_bib47","first-page":"367","article-title":"The evaluation of uveitis in juvenile idiopathic arthritis (JIA) patients: are current ophthalmologic screening guidelines adequate?","volume":"26","author":"Reininga","year":"2008","journal-title":"Clin Exp Rheumatol"},{"key":"10.1016\/j.rdc.2013.05.005_bib48","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1542\/peds.2006-0421","article-title":"Ophthalmologic examinations in children with juvenile rheumatoid arthritis","volume":"117","author":"Cassidy","year":"2006","journal-title":"Pediatrics"},{"issue":"5","key":"10.1016\/j.rdc.2013.05.005_bib49","first-page":"349","article-title":"Uveitis and psychological stress","volume":"20","author":"Khanfer","year":"2012","journal-title":"Ocul Immunol Inflamm"},{"key":"10.1016\/j.rdc.2013.05.005_bib50","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1016\/S0161-6420(84)34177-X","article-title":"Systemic uveitis syndromes in childhood: an analysis of 340 cases","volume":"91","author":"Kanski","year":"1984","journal-title":"Ophthalmology"},{"issue":"2","key":"10.1016\/j.rdc.2013.05.005_bib51","first-page":"11","article-title":"Risk factors for development of uveitis differ between girls and boys with juvenile idiopathic arthritis","volume":"37","author":"Saurenmann","year":"2012","journal-title":"Insight"},{"issue":"6","key":"10.1016\/j.rdc.2013.05.005_bib52","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1093\/rheumatology\/kem053","article-title":"Prevalence and complications of uveitis in juvenile idiopathic arthritis in a population-based nation-wide study in Germany: suggested modification of the current screening guidelines","volume":"46","author":"Heiligenhaus","year":"2007","journal-title":"Rheumatol Oxf"},{"issue":"10","key":"10.1016\/j.rdc.2013.05.005_bib53","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.1001\/archopht.1977.04450100096010","article-title":"Anterior uveitis in juvenile rheumatoid arthritis","volume":"95","author":"Kanski","year":"1977","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib54","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1016\/j.ophtha.2005.01.044","article-title":"Analysis of pediatric cases at a tertiary referral center","volume":"112","author":"Kump","year":"2005","journal-title":"Ophthalmology"},{"key":"10.1016\/j.rdc.2013.05.005_bib55","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1016\/j.ajo.2007.01.033","article-title":"Juvenile idiopathic arthritis-associated uveitis: incidence of ocular complications and visual acuity loss","volume":"143","author":"Thorne","year":"2007","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib56","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/S0002-9394(03)00315-5","article-title":"Laser flare photometry and complications of chronic uveitis in children","volume":"135","author":"Davis","year":"2003","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib57","first-page":"344","article-title":"A\u00a0reconsideration of anterior chamber flare and its clinical relevance for children with chronic anterior uveitis (an American Ophthalmological Society thesis)","volume":"105","author":"Holland","year":"2007","journal-title":"Trans Am Ophthalmol Soc"},{"issue":"3","key":"10.1016\/j.rdc.2013.05.005_bib58","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1590\/S0004-27492009000300028","article-title":"New insights into Vogt-Koyanagi-Harada disease","volume":"72","author":"Damico","year":"2009","journal-title":"Arq Bras Oftalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib59","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1080\/02713680802233968","article-title":"Vogt-Koyanagi-Harada Syndrome Mini Review","volume":"33","author":"Fang","year":"2008","journal-title":"Curr Eye Res"},{"issue":"2","key":"10.1016\/j.rdc.2013.05.005_bib60","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.ajo.2008.08.034","article-title":"Revised diagnostic criteria for Vogt-Koyanagi-Harada disease: considerations on the different disease categories","volume":"147","author":"da Silva","year":"2009","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib61","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1038\/sj.eye.6702859","article-title":"Vogt-Koyanagi-Harada disease in children","volume":"22","author":"El-Asrar","year":"2008","journal-title":"Eye"},{"issue":"3","key":"10.1016\/j.rdc.2013.05.005_bib62","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1080\/08820530500232126","article-title":"Vogt-Koyanagi-Harada disease","volume":"20","author":"Damico","year":"2005","journal-title":"Semin Ophthalmol"},{"issue":"3","key":"10.1016\/j.rdc.2013.05.005_bib63","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1097\/IIO.0b013e31817d9b70","article-title":"Vogt-Koyanagi-Harada syndrome in childhood","volume":"48","author":"Garcia","year":"2008","journal-title":"Int Ophthalmol Clin"},{"issue":"6","key":"10.1016\/j.rdc.2013.05.005_bib64","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1034\/j.1600-0420.1998.760619.x","article-title":"Vogt-Koyanagi-Harada syndrome in children compared to adults","volume":"76","author":"Tabbara","year":"1998","journal-title":"Acta Ophthalmol Scand"},{"issue":"3","key":"10.1016\/j.rdc.2013.05.005_bib65","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1136\/bjo.78.3.223","article-title":"HLA-DRB1 typing of Vogt-Koyanagi-Harada's disease by PCR-RFLP and the strong association with DRB1*0405 and DRB1*0410","volume":"78","author":"Shindo","year":"1994","journal-title":"Br J Ophthalmol"},{"issue":"5","key":"10.1016\/j.rdc.2013.05.005_bib66","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1016\/j.jaci.2007.01.010","article-title":"IL-23 promotes CD4+ T cells to produce IL-17 in Vogt-Koyanagi-Harada disease","volume":"119","author":"Chi","year":"2007","journal-title":"J\u00a0Allergy Clin Immunol"},{"issue":"8","key":"10.1016\/j.rdc.2013.05.005_bib67","doi-asserted-by":"crossref","first-page":"4668","DOI":"10.1167\/iovs.12-9863","article-title":"Decreased IL-27 expression in association with an increased Th17 response in Vogt-Koyanagi-Harada disease","volume":"53","author":"Wang","year":"2012","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"4","key":"10.1016\/j.rdc.2013.05.005_bib68","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.autrev.2010.10.002","article-title":"Autoimmune uveitis: the associated proinflammatory molecules and the search for immunoregulation","volume":"10","author":"Commodaro","year":"2011","journal-title":"Autoimmun Rev"},{"issue":"4","key":"10.1016\/j.rdc.2013.05.005_bib69","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0039-6257(05)80105-5","article-title":"Vogt-Koyanagi-Harada syndrome","volume":"39","author":"Moorthy","year":"1995","journal-title":"Surv Ophthalmol"},{"issue":"2","key":"10.1016\/j.rdc.2013.05.005_bib70","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1080\/09273940500536766","article-title":"Immunomodulatory therapy for Vogt-Koyanagi-Harada patients as first-line therapy","volume":"14","author":"Paredes","year":"2006","journal-title":"Ocul Immunol Inflamm"},{"issue":"2","key":"10.1016\/j.rdc.2013.05.005_bib71","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1097\/00004397-200604620-00011","article-title":"Vogt-Koyanagi-Harada disease","volume":"46","author":"Andreoli","year":"2006","journal-title":"Int Ophthalmol Clin"},{"issue":"5","key":"10.1016\/j.rdc.2013.05.005_bib72","first-page":"288","article-title":"Management of ocular complications of Vogt-Koyanagi-Harada syndrome","volume":"44","author":"Perente","year":"2007","journal-title":"J\u00a0Pediatr Ophthalmol Strabismus"},{"key":"10.1016\/j.rdc.2013.05.005_bib73","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1080\/09273940600557001","article-title":"Management of paediatric Vogt-Koyanagi-Harada (VKH)-associated panuve\u0131tis","volume":"14","author":"Soheilian","year":"2006","journal-title":"Ocul Immunol Inflamm"},{"issue":"4","key":"10.1016\/j.rdc.2013.05.005_bib74","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1007\/s11882-008-0054-2","article-title":"Biologic agents in the management of inflammatory eye diseases","volume":"8","author":"Michalova","year":"2008","journal-title":"Curr Allergy Asthma Rep"},{"issue":"3","key":"10.1016\/j.rdc.2013.05.005_bib75","doi-asserted-by":"crossref","first-page":"218","DOI":"10.3109\/09273941003739910","article-title":"Treatment of pediatric Vogt-Koyanagi-Harada syndrome with infliximab","volume":"18","author":"Khalifa","year":"2010","journal-title":"Ocul Immunol Inflamm"},{"key":"10.1016\/j.rdc.2013.05.005_bib76","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/S0002-9394(00)00659-0","article-title":"Guidelines for the use of immunosuppressive drugs in patients with ocular inflammatory disorders: recommendations of an expert panel","volume":"130","author":"Jabs","year":"2000","journal-title":"Am J Ophthalmol"},{"issue":"1","key":"10.1016\/j.rdc.2013.05.005_bib77","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.ajo.2006.02.049","article-title":"Evaluation of the effect on outcomes of the route of administration of corticosteroids in acute Vogt-Koyanagi-Harada disease","volume":"142","author":"Read","year":"2006","journal-title":"Am J Ophthalmol"},{"issue":"2\u20133","key":"10.1016\/j.rdc.2013.05.005_bib78","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/s10792-007-9062-9","article-title":"Prognostic factors in Vogt-Koyanagi-Harada disease","volume":"27","author":"Al-Kharashi","year":"2007","journal-title":"Int Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib79","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1046\/j.1442-9071.2001.d01-7.x","article-title":"Pars planitis: a comparison of childhood onset and adult onset disease","volume":"29","author":"Guest","year":"2001","journal-title":"Clin Experiment Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib80","doi-asserted-by":"crossref","first-page":"288","DOI":"10.3928\/01913913-20070901-03","article-title":"Pars planitis in children: epidemiologic, clinical, and therapeutic characteristics","volume":"44","author":"Romero","year":"2007","journal-title":"J\u00a0Pediatr Ophthalmol Strabismus"},{"issue":"4","key":"10.1016\/j.rdc.2013.05.005_bib81","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/j.ajo.2005.09.035","article-title":"Long-term follow-up of intermediate uveitis in children","volume":"141","author":"de Boer","year":"2006","journal-title":"Am J Ophthalmol"},{"issue":"1","key":"10.1016\/j.rdc.2013.05.005_bib82","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/S0002-9394(14)70994-8","article-title":"The association of HLA-DR15 and intermediate uveitis","volume":"123","author":"Tang","year":"1997","journal-title":"Am J Ophthalmol"},{"issue":"6","key":"10.1016\/j.rdc.2013.05.005_bib83","first-page":"611","article-title":"Retrospective analysis of children with uveitis treated with infliximab","volume":"12","author":"Tugal-Tutkun","year":"2008","journal-title":"J\u00a0AAPOS"},{"key":"10.1016\/j.rdc.2013.05.005_bib84","doi-asserted-by":"crossref","first-page":"765380","DOI":"10.5402\/2012\/765380","article-title":"High dose infliximab in the treatment of refractory uveitis: does dose really matter?","volume":"2012","author":"Sukumaran","year":"2012","journal-title":"ISRN Rheumatol"},{"issue":"5","key":"10.1016\/j.rdc.2013.05.005_bib85","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1136\/bjo.2010.184267","article-title":"Young age as a risk factor for complicated course and visual outcome in intermediate uveitis in children","volume":"95","author":"Kalinina Ayuso","year":"2011","journal-title":"Br\u00a0J Ophthalmol"},{"issue":"6","key":"10.1016\/j.rdc.2013.05.005_bib86","first-page":"1824","article-title":"Intermediate uveitis in a pediatric Italian population","volume":"62","author":"Paroli","year":"2010","journal-title":"Arthritis Rheum"},{"issue":"3","key":"10.1016\/j.rdc.2013.05.005_bib87","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0039-6257(01)00261-2","article-title":"The tubulointerstitial nephritis and uveitis syndrome","volume":"46","author":"Mandeville","year":"2001","journal-title":"Surv Ophthalmol"},{"issue":"3","key":"10.1016\/j.rdc.2013.05.005_bib88","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1097\/IIO.0b013e31817d8455","article-title":"Tubulointerstitial nephritis and uveitis syndrome","volume":"48","author":"Levinson","year":"2008","journal-title":"Int Ophthalmol Clin"},{"issue":"6","key":"10.1016\/j.rdc.2013.05.005_bib89","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1097\/ICU.0b013e3283318f9a","article-title":"Tubulointerstitial nephritis and uveitis syndrome","volume":"20","author":"Mackensen","year":"2009","journal-title":"Curr Opin Ophthalmol"},{"issue":"2","key":"10.1016\/j.rdc.2013.05.005_bib90","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1007\/s00467-010-1698-4","article-title":"Clinical outcome and occurrence of uveitis in children with idiopathic tubulointerstitial nephritis","volume":"26","author":"Jahnukainen","year":"2011","journal-title":"Pediatr Nephrol"},{"issue":"5","key":"10.1016\/j.rdc.2013.05.005_bib91","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1016\/j.ophtha.2007.01.002","article-title":"Enhanced recognition, treatment, and prognosis of tubulointerstitial nephritis and uveitis syndrome","volume":"114","author":"Mackensen","year":"2007","journal-title":"Ophthalmology"},{"key":"10.1016\/j.rdc.2013.05.005_bib92","first-page":"1152","article-title":"Uber rezidivierende Aphthose, durch ein Virus verursachte Geschwure am Mund, am Auge und an den Genitalien","volume":"105","author":"Beh\u00e7et","year":"1937","journal-title":"Dermatol Wochenschr"},{"key":"10.1016\/j.rdc.2013.05.005_bib93","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.ajo.2004.03.022","article-title":"Uveitis in Beh\u00e7et disease: an analysis of 880 patients","volume":"138","author":"Tugal-Tutkun","year":"2004","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib94","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1007\/s11910-005-0062-8","article-title":"Visual aspects of Beh\u00e7et\u2019s disease","volume":"5","author":"Kansu","year":"2005","journal-title":"Curr Neurol Neurosci Rep"},{"key":"10.1016\/j.rdc.2013.05.005_bib95","first-page":"291","article-title":"Clinical research section recommendations","volume":"18","author":"Beh\u00e7et\u2019s Disease Research Committee","year":"1974","journal-title":"Jpn J Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib96","first-page":"1078","article-title":"International Study Group for Beh\u00e7et\u2019s disease. Criteria for diagnosis of Beh\u00e7et\u2019s disease","volume":"335","year":"1990","journal-title":"Lancet"},{"key":"10.1016\/j.rdc.2013.05.005_bib97","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1007\/s00347-011-2503-x","article-title":"Epidemiology of ocular involvement in Adamantiades-Beh\u00e7ets disease","volume":"109","author":"Kneifel","year":"2012","journal-title":"Ophthalmologe"},{"key":"10.1016\/j.rdc.2013.05.005_bib98","doi-asserted-by":"crossref","first-page":"103","DOI":"10.3109\/09273948.2011.555592","article-title":"Beh\u00e7et disease in children","volume":"19","author":"Atmaca","year":"2011","journal-title":"Ocul Immunol Inflamm"},{"key":"10.1016\/j.rdc.2013.05.005_bib99","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.survophthal.2005.04.009","article-title":"Current concepts in the etiology and treatment of Beh\u00e7et\u2019s disease","volume":"50","author":"Evereklio\u011flu","year":"2005","journal-title":"Surv Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib100","first-page":"278","article-title":"A\u00a0nation-wide survey of Beh\u00e7et\u2019s disease in Japan","volume":"19","author":"Masuda","year":"1975","journal-title":"Jpn J Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib101","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1001\/archopht.1977.04450100115015","article-title":"The ocular manifestations in Beh\u00e7et\u2019s disease","volume":"95","author":"Colvard","year":"1977","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib102","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1093\/rheumatology\/35.3.258","article-title":"Rheumatic disorders of the eye and the various structures involved","volume":"35","author":"Hazleman","year":"1996","journal-title":"Br J Rheumatol"},{"key":"10.1016\/j.rdc.2013.05.005_bib103","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/S0886-3350(01)01023-9","article-title":"Cataract surgery in patients with Beh\u00e7et\u2019s disease","volume":"28","author":"Kadayifcilar","year":"2002","journal-title":"J\u00a0Cataract Refract Surg"},{"key":"10.1016\/j.rdc.2013.05.005_bib104","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1097\/00061198-200412000-00002","article-title":"Incidence of secondary glaucoma in Beh\u00e7et\u2019s disease","volume":"13","author":"Elgin","year":"2004","journal-title":"J\u00a0Glaucoma"},{"key":"10.1016\/j.rdc.2013.05.005_bib105","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1177\/112067210201200514","article-title":"Posterior segment involvement in ocular Beh\u00e7et's disease","volume":"12","author":"Ozdal","year":"2002","journal-title":"Eur J Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib106","unstructured":"Kaday\u0131f\u00e7\u0131lar S, Eldem B. Full thickness macular holes associated with Beh\u00e7et\u2019s disease. VIIth International Congress of International Ocular Inflammation Society. Padua, 2003, Abstract Book. p. 102."},{"key":"10.1016\/j.rdc.2013.05.005_bib107","first-page":"391","article-title":"Ocular findings in childhood-onset Beh\u00e7ets disease","volume":"13","author":"Citirik","year":"2009","journal-title":"J\u00a0AAPOS"},{"key":"10.1016\/j.rdc.2013.05.005_bib108","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1136\/bjo.2007.137141","article-title":"Clinical and demographic evaluation of Beh\u00e7ets disease among different paediatric age groups","volume":"93","author":"Sungur","year":"2009","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib109","first-page":"531","article-title":"Epidemiology and clinical aspects of Adamantiades\u2014Beh\u00e7et disease in Germany. Current data","volume":"109","author":"Altenburg Ai Mahr","year":"2012","journal-title":"Ophthalmologe"},{"key":"10.1016\/j.rdc.2013.05.005_bib110","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1007\/BF02169409","article-title":"Fundus changes associated with Beh\u00e7et\u2019s disease","volume":"227","author":"Atmaca","year":"1989","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib111","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1097\/IIO.0b013e318265d56a","article-title":"Imaging in the diagnosis and management of Beh\u00e7et\u2019s disease","volume":"52","author":"Tugal-Tutkun","year":"2012","journal-title":"Int Ophthalmol Clin"},{"key":"10.1016\/j.rdc.2013.05.005_bib112","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1097\/BOR.0b013e32833cc9b7","article-title":"Pediatric onset Beh\u00e7et disease","volume":"22","author":"Ozen","year":"2010","journal-title":"Curr Opin Rheumatol"},{"key":"10.1016\/j.rdc.2013.05.005_bib113","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1016\/S0002-9394(03)00791-8","article-title":"Childhood-onset uveitis in Beh\u00e7et disease: a descriptive study of 36 cases","volume":"136","author":"Tugal-Tutkun","year":"2003","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib114","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1136\/bjo.86.5.521","article-title":"High dose intravitreal steroid therapy for severe posterior segment uveitis in Beh\u00e7et\u2019s disease","volume":"86","author":"Toker","year":"2002","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib115","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1007\/s12009-007-0018-5","article-title":"Intravenous methylprednisolone pulse therapy for acute posterior segment uveitis attacks in Beh\u00e7et\u2019s disease","volume":"39","author":"Yal\u00e7\u0131ndag","year":"2007","journal-title":"Ann Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib116","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1136\/ard.2008.087957","article-title":"Management of Beh\u00e7et disease: a systematic literature review for the European League Against Rheumatism evidence-based recommendations for the management of Beh\u00e7et disease","volume":"68","author":"Hatemi","year":"2009","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.rdc.2013.05.005_bib117","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1016\/j.ajo.2004.04.064","article-title":"Intravitreal injection of triamcinolone acetonide for severe vitritis in patients with incomplete Beh\u00e7et\u2019s disease","volume":"138","author":"Kramer","year":"2004","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib118","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1089\/jop.2007.0015","article-title":"Results of intravitreal triamcinolone acetonide (IVTA) injection for the treatment of panuveitis attacks in patients with Beh\u00e7et disease","volume":"23","author":"Tuncer","year":"2007","journal-title":"J\u00a0Ocul Pharmacol Ther"},{"key":"10.1016\/j.rdc.2013.05.005_bib119","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1007\/s00417-006-0514-0","article-title":"Intravitreal triamcinolone acetonide in the management of cystoid macular edema in Beh\u00e7et\u2019s disease","volume":"245","author":"Atmaca","year":"2007","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib120","doi-asserted-by":"crossref","first-page":"2412","DOI":"10.1016\/j.ophtha.2012.07.025","article-title":"Dexamethasone implant in pediatric uveitis","volume":"119","author":"Taylor","year":"2012","journal-title":"Ophthalmology"},{"key":"10.1016\/j.rdc.2013.05.005_bib121","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1136\/bjo.87.4.423","article-title":"Human recombinant interferon-\u03b12a for the treatment of Beh\u00e7et\u2019s disease with sight threatening posterior or panuveitis","volume":"87","author":"Kotter","year":"2003","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib122","doi-asserted-by":"crossref","first-page":"1692","DOI":"10.1007\/s00417-006-0346-y","article-title":"Results of interferon alfa therapy in patients with Beh\u00e7et uveitis","volume":"244","author":"Tugal Tutkun","year":"2006","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib123","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1093\/rheumatology\/kem199","article-title":"Efficacy and safety of interferon-\u03b1 in the treatment of corticodependent uveitis of pediatric Beh\u00e7et\u2019s disease","volume":"46","author":"Guillaume-Czitrom","year":"2007","journal-title":"Rheumatology"},{"key":"10.1016\/j.rdc.2013.05.005_bib124","doi-asserted-by":"crossref","first-page":"2796","DOI":"10.1002\/art.27581","article-title":"Long-term remission after cessation of interferon-alpha treatment in patients with severe uveitis due to Beh\u00e7et\u2019s disease","volume":"62","author":"Deuter","year":"2010","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.rdc.2013.05.005_bib125","first-page":"14","article-title":"Infliximab in refractory uveitis due to Beh\u00e7et\u2019s disease","volume":"22","author":"Wechsler","year":"2004","journal-title":"Clin Exp Rheumatol"},{"key":"10.1016\/j.rdc.2013.05.005_bib126","doi-asserted-by":"crossref","first-page":"2478","DOI":"10.1002\/art.21231","article-title":"Efficacy of infliximab in the treatment of uveitis that is resistant to treatment with the combination of azathioprine, cyclosporine, and corticosteroids in Beh\u00e7et's disease: an open-label trial","volume":"52","author":"Tugal Tutkun","year":"2005","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.rdc.2013.05.005_bib127","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1093\/rheumatology\/kem101","article-title":"Long term efficacy of infliximab in refractory posterior uveitis of Beh\u00e7et\u2019s disease: a 24 month follow up study","volume":"46","author":"Niccoli","year":"2007","journal-title":"Rheumatology"},{"key":"10.1016\/j.rdc.2013.05.005_bib128","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1093\/rheumatology\/kem034","article-title":"Anti TNF therapy in the management of Beh\u00e7et\u2019s disease-review and basis for recommendations","volume":"46","author":"Sfikakis","year":"2007","journal-title":"Rheumatology"},{"key":"10.1016\/j.rdc.2013.05.005_bib129","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s10792-011-9430-3","article-title":"Adalimumab (HumiraTM): a promising monoclonal anti-tumor necrosis factor alpha in ophthalmology","volume":"31","author":"Neri","year":"2011","journal-title":"Int Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib130","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/j.rdc.2007.07.015","article-title":"Cogan\u2019s syndrome: an audio vestibular, ocular, and systemic autoimmune disease","volume":"33","author":"Mazlumzadeh","year":"2007","journal-title":"Rheum Dis Clin North Am"},{"key":"10.1016\/j.rdc.2013.05.005_bib131","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/S0140-6736(02)11028-2","article-title":"Autoantibodies to inner ear and endothelial antigens in Cogan\u2019s Syndrome","volume":"360","author":"Lunardi","year":"2002","journal-title":"Lancet"},{"key":"10.1016\/j.rdc.2013.05.005_bib132","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.jpeds.2011.07.051","article-title":"Clinical features and outcome of Cogan syndrome","volume":"160","author":"Pagnini","year":"2012","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.rdc.2013.05.005_bib133","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1097\/00004397-199603610-00008","article-title":"Cogan\u2019s syndrome: ophthalmic, audio vestibular and systemic manifestations and therapy","volume":"36","author":"Chynn","year":"1996","journal-title":"Int Ophtalmol Clin"},{"key":"10.1016\/j.rdc.2013.05.005_bib134","first-page":"1830","article-title":"Efficacy of methotrexate in Cogan\u2019s syndrome","volume":"23","author":"Riente","year":"1996","journal-title":"J\u00a0Rheumatol"},{"key":"10.1016\/j.rdc.2013.05.005_bib135","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1002\/art.1780371026","article-title":"Methotrexate therapy for hearing loss in Cogan\u2019s syndrome","volume":"37","author":"Richardson","year":"1994","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.rdc.2013.05.005_bib136","doi-asserted-by":"crossref","first-page":"49","DOI":"10.5387\/fms.46.49","article-title":"Atypical Cogan\u2019s syndrome successfully treated with glucocorticoids and pulse cyclophosphamide therapy","volume":"46","author":"Watanabe","year":"2000","journal-title":"Fukushima J Med Sci"},{"key":"10.1016\/j.rdc.2013.05.005_bib137","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1007\/s10067-009-1263-3","article-title":"Leflunomide for the successful management of juvenile Cogan\u2019s syndrome","volume":"28","author":"Xie","year":"2009","journal-title":"Clin Rheumatol"},{"key":"10.1016\/j.rdc.2013.05.005_bib138","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/S0002-9394(03)01122-X","article-title":"Cogan syndrome in children: early diagnosis and treatment is critical to prognosis","volume":"137","author":"Orsoni","year":"2004","journal-title":"Am J Ophthalmol"},{"issue":"1","key":"10.1016\/j.rdc.2013.05.005_bib139","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1136\/bjo.86.1.51","article-title":"An evaluation of baseline risk factors predicting severity in juvenile idiopathic arthritis associated uveitis and other chronic anterior uveitis in early childhood","volume":"86","author":"Edelsten","year":"2002","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib140","first-page":"217","article-title":"The ocular manifestations of juvenile rheumatoid arthritis","volume":"20","author":"Chylack","year":"1977","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.rdc.2013.05.005_bib141","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1001\/jama.280.13.1133","article-title":"Saving the vision of children with juvenile rheumatoid arthritis-associated uveitis","volume":"280","author":"Nguyen","year":"1998","journal-title":"JAMA"},{"issue":"3","key":"10.1016\/j.rdc.2013.05.005_bib142","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1097\/IAE.0b013e31822058bb","article-title":"Treatment of intractable posterior uveitis in pediatric patients with the fluocinolone acetonide intravitreal implant (Retisert)","volume":"32","author":"Patel","year":"2012","journal-title":"Retina"},{"issue":"5","key":"10.1016\/j.rdc.2013.05.005_bib143","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1093\/rheumatology\/kes186","article-title":"Current evidence of methotrexate efficacy in childhood chronic uveitis: a systematic review and meta-analysis approach","volume":"52","author":"Simonini","year":"2013","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.rdc.2013.05.005_bib144","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1016\/S0161-6420(01)00576-0","article-title":"Methotrexate therapy for chronic noninfectious uveitis: analysis of a case series of 160 patients","volume":"108","author":"Samson","year":"2001","journal-title":"Ophthalmology"},{"key":"10.1016\/j.rdc.2013.05.005_bib145","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/S0022-3476(98)70232-X","article-title":"Methotrexate for resistant chronic uveitis in children with juvenile rheumatoid arthritis","volume":"133","author":"Weiss","year":"1998","journal-title":"J\u00a0Pediatr"},{"key":"10.1016\/j.rdc.2013.05.005_bib146","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1136\/bjo.2004.054239","article-title":"The use of low dose methotrexate in children with chronic anterior and intermediate uveitis","volume":"89","author":"Malik","year":"2005","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib147","first-page":"362","article-title":"Methotrexate is an effective treatment for chronic uveitis associated with juvenile idiopathic arthritis","volume":"32","author":"Foeldvari","year":"2005","journal-title":"J\u00a0Rheumatol"},{"key":"10.1016\/j.rdc.2013.05.005_bib148","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1159\/000081784","article-title":"Intraocular levels of methotrexate after oral low-dose treatment in chronic uveitis","volume":"219","author":"Puchta","year":"2005","journal-title":"Ophthalmologica"},{"issue":"2","key":"10.1016\/j.rdc.2013.05.005_bib149","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.ajo.2010.08.021","article-title":"Relapse rate of uveitis post-methotrexate treatment in juvenile idiopathic arthritis","volume":"151","author":"Kalinina Ayuso","year":"2011","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib150","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1136\/bjo.82.7.737","article-title":"Cyclosporin A therapy in refractory non- infectious childhood uveitis","volume":"82","author":"Kilmartin","year":"1998","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib151","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0140-6736(05)79515-5","article-title":"Rescue therapy with mycophenolate mofetil in refractory uveitis","volume":"352","author":"Thorne","year":"1998","journal-title":"Lancet"},{"key":"10.1016\/j.rdc.2013.05.005_bib152","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1046\/j.1442-9071.2003.00704.x","article-title":"Long-term efficacy of mycophenolate mofetil in the control of severe intraocular inflammation","volume":"31","author":"Lau","year":"2003","journal-title":"Clin Experiment Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib153","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1076\/ocii.6.2.101.4051","article-title":"Tacrolimus (FK506) in failed cyclosporin A therapy in endogenous posterior uveitis","volume":"6","author":"Kilmartin","year":"1998","journal-title":"Ocul Immunol Inflamm"},{"key":"10.1016\/j.rdc.2013.05.005_bib154","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/S0002-9394(14)73645-1","article-title":"A\u00a0clinical trial of FK506 in refractory uveitis","volume":"115","author":"Mochizuki","year":"1993","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib155","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1093\/rheumatology\/40.8.907","article-title":"Efficacy and safety profile of cyclosporin A in the treatment of juvenile chronic (idiopathic) arthritis. Results of a 10-year prospective study","volume":"40","author":"Gerloni","year":"2001","journal-title":"Rheumatology"},{"issue":"1","key":"10.1016\/j.rdc.2013.05.005_bib156","doi-asserted-by":"crossref","first-page":"21","DOI":"10.3341\/kjo.2012.26.1.21","article-title":"Clinical outcomes of cyclosporine treatment for noninfectious uveitis","volume":"26","author":"Lee","year":"2012","journal-title":"Korean J Ophthalmol"},{"issue":"1","key":"10.1016\/j.rdc.2013.05.005_bib157","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/1546-0096-9-34","article-title":"Childhood chronic anterior uveitis associated with vernal keratoconjunctivitis (VKC): successful treatment with topical tacrolimus. Case series","volume":"9","author":"Taddio","year":"2011","journal-title":"Pediatr Rheumatol Online J"},{"issue":"8","key":"10.1016\/j.rdc.2013.05.005_bib158","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1007\/s00417-011-1731-8","article-title":"Long-term results of therapy with mycophenolate mofetil in chronic non-infectious uveitis","volume":"249","author":"Doycheva","year":"2011","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"3","key":"10.1016\/j.rdc.2013.05.005_bib159","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.ajo.2009.09.026","article-title":"Mycophenolate mofetil for ocular inflammation","volume":"149","author":"Daniel","year":"2010","journal-title":"Am J Ophthalmol"},{"issue":"5","key":"10.1016\/j.rdc.2013.05.005_bib160","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/j.ajo.2008.03.004","article-title":"Mycophenolate mofetil for the treatment of uveitis","volume":"146","author":"Teoh","year":"2008","journal-title":"Am J Ophthalmol"},{"issue":"2","key":"10.1016\/j.rdc.2013.05.005_bib161","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1136\/bjo.2006.094698","article-title":"Mycophenolate mofetil in the treatment of uveitis in children","volume":"91","author":"Doycheva","year":"2007","journal-title":"Br J Ophthalmol"},{"issue":"4","key":"10.1016\/j.rdc.2013.05.005_bib162","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1038\/eye.2011.23","article-title":"Mycophenolate mofetil monotherapy in the management of paediatric uveitis","volume":"25","author":"Chang","year":"2011","journal-title":"Eye (Lond)"},{"issue":"1","key":"10.1016\/j.rdc.2013.05.005_bib163","doi-asserted-by":"crossref","first-page":"28","DOI":"10.3928\/01913913-20070101-03","article-title":"Immunosuppressants used in a steroid-sparing strategy for childhood uveitis","volume":"44","author":"Schatz","year":"2007","journal-title":"J\u00a0Pediatr Ophthalmol Strabismus"},{"issue":"10","key":"10.1016\/j.rdc.2013.05.005_bib164","doi-asserted-by":"crossref","first-page":"1826","DOI":"10.1016\/j.ophtha.2008.04.026","article-title":"Comparison of antimetabolite drugs as corticosteroid-sparing therapy for noninfectious ocular inflammation","volume":"115","author":"Galor","year":"2008","journal-title":"Ophthalmology"},{"issue":"2","key":"10.1016\/j.rdc.2013.05.005_bib165","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1111\/j.1600-0420.2006.00858.x","article-title":"The treatment of multifocal choroiditis associated choroidal neovascularization with sirolimus (rapamycin)","volume":"85","author":"Nussenblatt","year":"2007","journal-title":"Acta Ophthalmol Scand"},{"issue":"6","key":"10.1016\/j.rdc.2013.05.005_bib166","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1136\/bjo.2004.048199","article-title":"The efficacy of sirolimus in the treatment of patients with refractory uveitis","volume":"89","author":"Shanmuganathan","year":"2005","journal-title":"Br J Ophthalmol"},{"issue":"7","key":"10.1016\/j.rdc.2013.05.005_bib167","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1097\/TP.0b013e31825b411c","article-title":"A\u00a0comprehensive review of everolimus clinical reports: a new mammalian target of rapamycin inhibitor","volume":"94","author":"Gurk-Turner","year":"2012","journal-title":"Transplantation"},{"issue":"1","key":"10.1016\/j.rdc.2013.05.005_bib168","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/s00417-012-2163-9","article-title":"Everolimus for the treatment of uveitis refractory to cyclosporine A: a pilot study","volume":"251","author":"Heiligenhaus","year":"2013","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib169","first-page":"377","article-title":"Cytotoxic agents in ocular inflammation","volume":"10","author":"Ramadan","year":"1997","journal-title":"Ophthalmol Clin North Am"},{"key":"10.1016\/j.rdc.2013.05.005_bib170","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1001\/archopht.1978.03910050115002","article-title":"Immunosuppressive therapy for severe chronic uveitis","volume":"96","author":"Andrasch","year":"1978","journal-title":"Arch Ophthalmol"},{"issue":"1","key":"10.1016\/j.rdc.2013.05.005_bib171","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s12348-011-0047-5","article-title":"Corticosteroid-sparing therapy: practice patterns among uveitis specialists","volume":"2","author":"Esterberg","year":"2012","journal-title":"J\u00a0Ophthalmic Inflamm Infect"},{"issue":"6","key":"10.1016\/j.rdc.2013.05.005_bib172","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.semarthrit.2012.10.006","article-title":"The use of biologic response modifiers in polyarticular-course juvenile idiopathic arthritis: a systematic review","volume":"42","author":"Ungar","year":"2013","journal-title":"Semin Arthritis Rheum"},{"key":"10.1016\/j.rdc.2013.05.005_bib173","first-page":"3884","article-title":"The role of tumor necrosis factor-alpha in the induction of experimental autoimmune uveoretinitis in mice","volume":"35","author":"Nakamura","year":"1994","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.rdc.2013.05.005_bib174","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1076\/ocii.6.2.111.4046","article-title":"Intraocular cytokine quantification of experimental autoimmune uveoretinitis in rats","volume":"6","author":"Okada","year":"1998","journal-title":"Ocul Immunol Inflamm"},{"key":"10.1016\/j.rdc.2013.05.005_bib175","first-page":"3873","article-title":"Expression of multiple cytokines and IL-1RA in the uvea and retina during endotoxin-induced uveitis in the rat","volume":"35","author":"De Vos","year":"1994","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.rdc.2013.05.005_bib176","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1002\/eji.1830260510","article-title":"Inhibition of tumor necrosis factor activity minimizes target organ damage in experimental autoimmune uveoretinitis despite quantitatively normal activated T cell traffic to the retina","volume":"26","author":"Dick","year":"1996","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.rdc.2013.05.005_bib177","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1002\/1529-0131(200106)44:6<1411::AID-ART235>3.0.CO;2-O","article-title":"Etanercept therapy in children with treatment-resistant uveitis","volume":"44","author":"Reiff","year":"2001","journal-title":"Arthritis Rheum"},{"issue":"3","key":"10.1016\/j.rdc.2013.05.005_bib178","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1007\/s00347-010-2260-2","article-title":"Therapy for childhood uveitis: biologics: too often\u2014too late?","volume":"108","author":"Mackensen","year":"2011","journal-title":"Ophthalmologe"},{"issue":"4","key":"10.1016\/j.rdc.2013.05.005_bib179","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1136\/ard.2006.058248","article-title":"Infliximab and etanercept in the treatment of chronic uveitis associated with refractory juvenile idiopathic arthritis","volume":"66","author":"Tynj\u00e4l\u00e4","year":"2007","journal-title":"Ann Rheum Dis"},{"issue":"10","key":"10.1016\/j.rdc.2013.05.005_bib180","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1136\/bjo.2007.124081","article-title":"Biological response modifier therapy for refractory childhood uveitis","volume":"91","author":"Gallagher","year":"2007","journal-title":"Br J Ophthalmol"},{"issue":"5","key":"10.1016\/j.rdc.2013.05.005_bib181","first-page":"1146","article-title":"Tumor necrosis factor-alpha blocker in treatment of juvenile idiopathic arthritis-associated uveitis refractory to second-line agents: results of a multinational survey","volume":"34","author":"Foeldvari","year":"2007","journal-title":"J\u00a0Rheumatol"},{"issue":"6","key":"10.1016\/j.rdc.2013.05.005_bib182","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/j.ajo.2007.08.018","article-title":"Infliximab to treat chronic noninfectious uveitis in children: retrospective case series with long-term follow-up","volume":"144","author":"Ardoin","year":"2007","journal-title":"Am J Ophthalmol"},{"issue":"12","key":"10.1016\/j.rdc.2013.05.005_bib183","doi-asserted-by":"crossref","first-page":"2199","DOI":"10.1093\/rheumatology\/kes212","article-title":"Use of adalimumab in refractory non-infectious childhood chronic uveitis: efficacy in ocular disease\u2014a case cohort interventional study","volume":"51","author":"Sen","year":"2012","journal-title":"Rheumatology (Oxford)"},{"issue":"8","key":"10.1016\/j.rdc.2013.05.005_bib184","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1016\/j.ophtha.2012.02.018","article-title":"Treatment of refractory uveitis with adalimumab: a prospective multicenter study of 131 patients","volume":"119","author":"D\u00edaz-Llopis","year":"2012","journal-title":"Ophthalmology"},{"issue":"1","key":"10.1016\/j.rdc.2013.05.005_bib185","doi-asserted-by":"crossref","first-page":"74","DOI":"10.3899\/jrheum.120583","article-title":"Safety and efficacy of infliximab and adalimumab for refractory uveitis in juvenile idiopathic arthritis: 1-year followup data from the Italian Registry","volume":"40","author":"Zannin","year":"2013","journal-title":"J\u00a0Rheumatol"},{"issue":"2","key":"10.1016\/j.rdc.2013.05.005_bib186","first-page":"320","article-title":"Golimumab treatment for complicated uveitis","volume":"31","author":"Miserocchi","year":"2013","journal-title":"Clin Exp Rheumatol"},{"issue":"4","key":"10.1016\/j.rdc.2013.05.005_bib187","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/s12348-012-0081-y","article-title":"Golimumab for the treatment of refractory juvenile idiopathic arthritis-associated uveitis","volume":"2","author":"William","year":"2012","journal-title":"J\u00a0Ophthalmic Inflamm Infect"},{"key":"10.1016\/j.rdc.2013.05.005_bib188","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0165-5728(98)00075-7","article-title":"Increased vascular endothelial growth factor (VEGF) and transforming growth factor beta (TGF-beta) in experimental autoimmune uveoretinitis upregulation of VEGF without neovascularization","volume":"89","author":"Vinores","year":"1998","journal-title":"J\u00a0Neuroimmunol"},{"issue":"5\u00a0Suppl 1","key":"10.1016\/j.rdc.2013.05.005_bib189","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.semarthrit.2005.01.009","article-title":"Tumor necrosis factor and granuloma biology: explaining the differential infection risk of etanercept","volume":"34","author":"Wallis","year":"2005","journal-title":"Semin Arthritis Rheum"},{"issue":"1","key":"10.1016\/j.rdc.2013.05.005_bib190","doi-asserted-by":"crossref","first-page":"12","DOI":"10.3109\/09273948.2012.723107","article-title":"Systematic review of anti-tumor necrosis factor-alpha therapy for treatment of immune-mediated uveitis","volume":"21","author":"Cordero-Coma","year":"2013","journal-title":"Ocul Immunol Inflamm"},{"issue":"1","key":"10.1016\/j.rdc.2013.05.005_bib191","first-page":"26","article-title":"Optic neuritis associated with etanercept therapy for juvenile arthritis","volume":"10","author":"Tauber","year":"2006","journal-title":"J\u00a0AAPOS"},{"issue":"3","key":"10.1016\/j.rdc.2013.05.005_bib192","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.semarthrit.2011.05.005","article-title":"New onset of uveitis during anti-tumor necrosis factor treatment for rheumatic diseases","volume":"41","author":"Wendling","year":"2011","journal-title":"Semin Arthritis Rheum"},{"issue":"2","key":"10.1016\/j.rdc.2013.05.005_bib193","doi-asserted-by":"crossref","first-page":"233","DOI":"10.3899\/jrheum.110865","article-title":"Scleritis: a paradoxical effect of etanercept? Etanercept-associated inflammatory eye disease","volume":"39","author":"Gaujoux-Viala","year":"2012","journal-title":"J\u00a0Rheumatol"},{"issue":"3","key":"10.1016\/j.rdc.2013.05.005_bib194","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/j.ajo.2012.03.035","article-title":"Intravitreal infliximab for sight-threatening relapsing uveitis in Beh\u00e7et disease: a pilot study in 15 patients","volume":"154","author":"Markomichelakis","year":"2012","journal-title":"Am J Ophthalmol"},{"issue":"6","key":"10.1016\/j.rdc.2013.05.005_bib195","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1089\/jop.2011.0199","article-title":"Long-term effects of intravitreal infliximab for treatment of sight threatening chronic noninfectious uveitis","volume":"28","author":"Farvardin","year":"2012","journal-title":"J\u00a0Ocul Pharmacol Ther"},{"key":"10.1016\/j.rdc.2013.05.005_bib196","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1001\/archopht.123.7.957","article-title":"Suppression of immune-mediated ocular inflammation in mice by interleukin 1 receptor antagonist administration","volume":"123","author":"Lim","year":"2005","journal-title":"Arch Ophthalmol"},{"issue":"4","key":"10.1016\/j.rdc.2013.05.005_bib197","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1136\/annrheumdis-2011-155143","article-title":"Interleukin-1\u03b2-regulating antibody XOMA 052 (gevokizumab) in the treatment of acute exacerbations of resistant uveitis of Beh\u00e7et\u2019s disease: an open-label pilot study","volume":"71","author":"G\u00fcl","year":"2012","journal-title":"Ann Rheum Dis"},{"issue":"9","key":"10.1016\/j.rdc.2013.05.005_bib198","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1136\/annrheumdis-2012-201383","article-title":"Canakinumab in a patient with juvenile Beh\u00e7et\u2019s syndrome with refractory eye disease","volume":"71","author":"Ugurlu","year":"2012","journal-title":"Ann Rheum Dis"},{"issue":"2","key":"10.1016\/j.rdc.2013.05.005_bib199","first-page":"113","article-title":"Clinical and transcriptomic response to the long-acting IL-1 blocker canakinumab in Blau syndrome-related uveitis","volume":"11","author":"Simonini","year":"2012","journal-title":"Antiinflamm Antiallergy Agents Med Chem"},{"issue":"5","key":"10.1016\/j.rdc.2013.05.005_bib200","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1007\/s00417-009-1043-4","article-title":"Intravenous daclizumab for recalcitrant ocular inflammatory disease","volume":"247","author":"Bhat","year":"2009","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"4","key":"10.1016\/j.rdc.2013.05.005_bib201","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1136\/annrheumdis-2012-202469","article-title":"Consensus statement on blocking the effects of interleukin-6 and in particular by interleukin-6 receptor inhibition in rheumatoid arthritis and other inflammatory conditions","volume":"72","author":"Smolen","year":"2013","journal-title":"Ann Rheum Dis"},{"issue":"13","key":"10.1016\/j.rdc.2013.05.005_bib202","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1056\/NEJMc1301017","article-title":"Tocilizumab for systemic juvenile idiopathic arthritis","volume":"368","author":"De Benedetti","year":"2013","journal-title":"N\u00a0Engl J Med"},{"issue":"6","key":"10.1016\/j.rdc.2013.05.005_bib203","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.3899\/jrheum.120010","article-title":"Is tocilizumab an effective option for treatment of refractory uveitis associated with juvenile idiopathic arthritis?","volume":"39","author":"Tappeiner","year":"2012","journal-title":"J\u00a0Rheumatol"},{"issue":"5","key":"10.1016\/j.rdc.2013.05.005_bib204","doi-asserted-by":"crossref","first-page":"382","DOI":"10.3109\/09273948.2011.606593","article-title":"Efficacy of tocilizumab in two patients with anti-TNF-alpha refractory uveitis","volume":"19","author":"Muselier","year":"2011","journal-title":"Ocul Immunol Inflamm"},{"issue":"1","key":"10.1016\/j.rdc.2013.05.005_bib205","doi-asserted-by":"crossref","first-page":"48","DOI":"10.3109\/03009742.2012.704391","article-title":"Elevated levels of interleukin-27 and effect on production of interferon-\u03b3 and interleukin-17 in patients with Beh\u00e7et's disease","volume":"42","author":"Shen","year":"2013","journal-title":"Scand J Rheumatol"},{"issue":"2","key":"10.1016\/j.rdc.2013.05.005_bib206","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1167\/iovs.11-8505","article-title":"Increased IL-7 expression in Vogt-Koyanagi-Harada disease","volume":"53","author":"Yang","year":"2012","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"4","key":"10.1016\/j.rdc.2013.05.005_bib207","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/j.ophtha.2012.09.040","article-title":"Secukinumab in the treatment of noninfectious uveitis: results of three randomized, controlled clinical trials","volume":"120","author":"Dick","year":"2013","journal-title":"Ophthalmology"},{"issue":"2","key":"10.1016\/j.rdc.2013.05.005_bib208","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.reuma.2011.08.002","article-title":"Abatacept mechanism of action: concordance with its clinical profile","volume":"8","author":"Herrero-Beaumont","year":"2012","journal-title":"Reumatol Clin"},{"issue":"6","key":"10.1016\/j.rdc.2013.05.005_bib209","doi-asserted-by":"crossref","first-page":"787","DOI":"10.3899\/jrheum.120906","article-title":"Safety of abatacept administered intravenously in treatment of rheumatoid arthritis: integrated analyses of up to 8 years of treatment from the Abatacept Clinical Trial Program","volume":"40","author":"Weinblatt","year":"2013","journal-title":"J\u00a0Rheumatol"},{"issue":"6","key":"10.1016\/j.rdc.2013.05.005_bib210","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1002\/art.27431","article-title":"Long-term safety and efficacy of abatacept in children with juvenile idiopathic arthritis","volume":"62","author":"Ruperto","year":"2010","journal-title":"Arthritis Rheum"},{"issue":"2","key":"10.1016\/j.rdc.2013.05.005_bib211","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1007\/s00417-010-1523-6","article-title":"Abatacept: a potential therapy in refractory cases of juvenile idiopathic arthritis-associated uveitis","volume":"249","author":"Kenawy","year":"2011","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"9","key":"10.1016\/j.rdc.2013.05.005_bib212","first-page":"1897","article-title":"Abatacept for refractory juvenile idiopathic arthritis-associated uveitis- a case report","volume":"35","author":"Angeles-Han","year":"2008","journal-title":"J\u00a0Rheumatol"},{"issue":"2","key":"10.1016\/j.rdc.2013.05.005_bib213","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1002\/acr.20359","article-title":"Abatacept for refractory juvenile idiopathic arthritis-associated uveitis: two new cases. Comment on the article by Zulian et\u00a0al","volume":"63","author":"Elhai","year":"2011","journal-title":"Arthritis Care Res (Hoboken)"},{"issue":"6","key":"10.1016\/j.rdc.2013.05.005_bib214","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1002\/acr.20115","article-title":"Abatacept for severe anti-tumor necrosis factor alpha refractory juvenile idiopathic arthritis-related uveitis","volume":"62","author":"Zulian","year":"2010","journal-title":"Arthritis Care Res (Hoboken)"},{"issue":"6","key":"10.1016\/j.rdc.2013.05.005_bib215","first-page":"676","article-title":"Mechanisms of action of CD20 antibodies","volume":"2","author":"Boross","year":"2012","journal-title":"Am J Cancer Res"},{"key":"10.1016\/j.rdc.2013.05.005_bib216","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1159\/000336188","article-title":"Rituximab for noninfectious uveitis","volume":"51","author":"Miserocchi","year":"2012","journal-title":"Dev Ophthalmol"},{"issue":"1","key":"10.1016\/j.rdc.2013.05.005_bib217","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.autrev.2011.07.001","article-title":"Anti-CD 20 monoclonal antibody (rituximab) treatment for inflammatory ocular diseases","volume":"11","author":"Miserocchi","year":"2011","journal-title":"Autoimmun Rev"},{"issue":"8","key":"10.1016\/j.rdc.2013.05.005_bib218","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1093\/rheumatology\/ker107","article-title":"Treatment of severe uveitis associated with juvenile idiopathic arthritis with anti-CD20 monoclonal antibody (rituximab)","volume":"50","author":"Heiligenhaus","year":"2011","journal-title":"Rheumatology (Oxford)"},{"issue":"11","key":"10.1016\/j.rdc.2013.05.005_bib219","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1136\/bjo.79.11.1054","article-title":"Monoclonal antibody therapy of chronic intraocular inflammation using Campath-1H","volume":"79","author":"Isaacs","year":"1995","journal-title":"Br J Ophthalmol"},{"issue":"2","key":"10.1016\/j.rdc.2013.05.005_bib220","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1517\/14728214.2011.537824","article-title":"Emerging drugs for uveitis","volume":"16","author":"Larson","year":"2011","journal-title":"Expert Opin Emerg Drugs"},{"issue":"11","key":"10.1016\/j.rdc.2013.05.005_bib221","first-page":"2412","article-title":"Application of small molecules\/macromolecules in ocular inflammatory diseases","volume":"119","author":"Liu","year":"2012","journal-title":"Ophthalmology"},{"issue":"4","key":"10.1016\/j.rdc.2013.05.005_bib222","first-page":"522","article-title":"Novel IL27p28\/IL12p40 cytokine suppressed experimental autoimmune uveitis by inhibiting autoreactive Th1\/Th17 cells and promoting expansion of regulatory T cells","volume":"89","author":"Wang","year":"2009","journal-title":"Exp Eye Res"},{"key":"10.1016\/j.rdc.2013.05.005_bib223","first-page":"2586","article-title":"Amelioration of endotoxin-induced uveitis treated with an I\u03baB kinase \u03b2 inhibitor in rats","volume":"18","author":"Lennikov","year":"2012","journal-title":"Mol Vis"},{"issue":"2","key":"10.1016\/j.rdc.2013.05.005_bib224","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1167\/iovs.08-2372","article-title":"Efficient intraocular penetration of topical anti-TNF-alpha single-chain antibody (ESBA105) to anterior and posterior segment without penetration enhancer","volume":"50","author":"Ottiger","year":"2009","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"4","key":"10.1016\/j.rdc.2013.05.005_bib225","first-page":"259","article-title":"Pediatric uveitis","volume":"6","author":"Tugal-Tutkun","year":"2011","journal-title":"J\u00a0Ophthalmic Vis Res"},{"issue":"3","key":"10.1016\/j.rdc.2013.05.005_bib226","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1007\/s00417-005-0087-3","article-title":"Incidence and outcomes of uveitis in juvenile rheumatoid arthritis, a synthesis of the literature","volume":"244","author":"Carvounis","year":"2006","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"12","key":"10.1016\/j.rdc.2013.05.005_bib227","first-page":"2370","article-title":"Visual prognosis in children with chronic anterior uveitis and arthritis","volume":"21","author":"Cabral","year":"1994","journal-title":"J\u00a0Rheumatol"},{"issue":"1","key":"10.1016\/j.rdc.2013.05.005_bib228","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.ophtha.2012.07.052","article-title":"Risk factors for loss of visual acuity among patients with uveitis associated with juvenile idiopathic arthritis: the Systemic Immunosuppressive Therapy for Eye Diseases Study","volume":"120","author":"Gregory","year":"2013","journal-title":"Ophthalmology"},{"issue":"12","key":"10.1016\/j.rdc.2013.05.005_bib229","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1055\/s-2005-858753","article-title":"Epidemiology of uveitis in juvenile idiopathic arthritis from a national paediatric rheumatologic and ophthalmologic database","volume":"222","author":"Heiligenhaus","year":"2005","journal-title":"Klin Monbl Augenheilkd"},{"issue":"4","key":"10.1016\/j.rdc.2013.05.005_bib230","doi-asserted-by":"crossref","first-page":"262","DOI":"10.3109\/09273948.2012.684420","article-title":"Vision-related quality of life and employment status in patients with uveitis of working age: a prospective study","volume":"20","author":"Jalil","year":"2012","journal-title":"Ocul Immunol Inflamm"},{"issue":"5\u20136","key":"10.1016\/j.rdc.2013.05.005_bib231","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/BF00163549","article-title":"The natural history of uveitis","volume":"14","author":"Nussenblatt","year":"1990","journal-title":"Int Ophthalmol"},{"key":"10.1016\/j.rdc.2013.05.005_bib232","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1001\/archopht.1962.00960030506014","article-title":"Epidemiology of uveitis. Incidence and prevalence in a small urban community","volume":"68","author":"Darrell","year":"1962","journal-title":"Arch Ophthalmol"}],"container-title":["Rheumatic Disease Clinics of North America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889857X13000677?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889857X13000677?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T11:13:08Z","timestamp":1760181188000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0889857X13000677"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11]]},"references-count":232,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["S0889857X13000677"],"URL":"https:\/\/doi.org\/10.1016\/j.rdc.2013.05.005","relation":{},"ISSN":["0889-857X"],"issn-type":[{"type":"print","value":"0889-857X"}],"subject":[],"published":{"date-parts":[[2013,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Rheumatic Inflammatory Eye Diseases of Childhood","name":"articletitle","label":"Article Title"},{"value":"Rheumatic Disease Clinics of North America","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rdc.2013.05.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}