{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T14:26:25Z","timestamp":1782311185005,"version":"3.54.5"},"reference-count":35,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100012513","name":"CIBERCV","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012513","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004837","name":"Ministerio de Ciencia e Innovaci\u00f3n","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","elsevier.es","revespcardiol.org","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Revista Espa\u00f1ola de Cardiolog\u00eda (English Edition)"],"published-print":{"date-parts":[[2023,11]]},"DOI":"10.1016\/j.rec.2023.03.015","type":"journal-article","created":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T16:54:45Z","timestamp":1682441685000},"page":"891-900","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Meteorin-like protein is associated with a higher risk profile and predicts a worse outcome in patients with STEMI"],"prefix":"10.1016","volume":"76","author":[{"given":"Gemma","family":"Ferrer-Curriu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferran","family":"Rueda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Revuelta-L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cosme","family":"Garc\u00eda-Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pau","family":"Codina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"G\u00e1lvez-Mont\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santiago","family":"Roura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Aimo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Emdin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Planavila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoni","family":"Bay\u00e9s-Gen\u00eds","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.rec.2023.03.015_bib0180","doi-asserted-by":"crossref","first-page":"3056","DOI":"10.1093\/eurheartj\/ehx515","article-title":"Improved outcomes in patients with ST-elevation myocardial infarction during the last 20 years are related to implementation of evidence-based treatments: experiences from the SWEDEHEART registry 1995-2014","volume":"38","author":"Szummer","year":"2017","journal-title":"Eur Heart J."},{"key":"10.1016\/j.rec.2023.03.015_bib0185","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.ahj.2019.05.007","article-title":"Twenty-year trends in profile, management and outcomes of patients with ST-segment elevation myocardial infarction according to use of reperfusion therapy: Data from the FAST-MI program 1995-2015","volume":"214","author":"Puymirat","year":"2019","journal-title":"Am Heart J."},{"key":"10.1016\/j.rec.2023.03.015_bib0190","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1038\/aps.2016.9","article-title":"Metrnl: a secreted protein with new emerging functions","volume":"37","author":"Zheng","year":"2016","journal-title":"Acta Pharmacol Sin."},{"key":"10.1016\/j.rec.2023.03.015_bib0195","first-page":"1","article-title":"METRNL attenuates lipid-induced inflammation and insulin resistance via AMPK or PPAR\u03b4-dependent pathways in skeletal muscle of mice","volume":"50","author":"Jung","year":"2018","journal-title":"Exp Mol Med."},{"key":"10.1016\/j.rec.2023.03.015_bib0200","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1016\/j.cell.2014.03.065","article-title":"Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis","volume":"157","author":"Rao","year":"2014","journal-title":"Cell."},{"key":"10.1016\/j.rec.2023.03.015_bib0205","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1038\/ijo.2017.268","article-title":"Opposite changes in meteorin-like and oncostatin m levels are associated with metabolic improvements after bariatric surgery","volume":"42","author":"Pellitero","year":"2018","journal-title":"Int J Obes (Lond)."},{"key":"10.1016\/j.rec.2023.03.015_bib0210","doi-asserted-by":"crossref","first-page":"2337","DOI":"10.12659\/MSM.915331","article-title":"Serum Levels of Meteorin-Like (Metrnl) Are Increased in Patients with Newly Diagnosed Type 2 Diabetes Mellitus and Are Associated with Insulin Resistance","volume":"25","author":"Wang","year":"2019","journal-title":"Med Sci Monit."},{"key":"10.1016\/j.rec.2023.03.015_bib0215","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20201206","article-title":"Meteorin-like\/Meteorin-\u03b2 protects heart against cardiac dysfunction","volume":"218","author":"Rup\u00e9rez","year":"2021","journal-title":"J Exp Med."},{"key":"10.1016\/j.rec.2023.03.015_bib0220","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1126\/science.abn3027","article-title":"Meteorin-like promotes heart repair through endothelial KIT receptor tyrosine kinase","volume":"376","author":"Reboll","year":"2022","journal-title":"Science (80-)."},{"key":"10.1016\/j.rec.2023.03.015_bib0225","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.clim.2014.11.006","article-title":"METEORIN-LIKE is a cytokine associated with barrier tissues and alternatively activated macrophages","volume":"156","author":"Ushach","year":"2015","journal-title":"Clin Immunol."},{"key":"10.1016\/j.rec.2023.03.015_bib0230","doi-asserted-by":"crossref","first-page":"2551","DOI":"10.1093\/eurheartj\/ehs184","article-title":"Third universal definition of myocardial infarction","volume":"33","author":"Thygesen","year":"2012","journal-title":"Eur Heart J."},{"key":"10.1016\/j.rec.2023.03.015_bib0235","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.1093\/eurheartj\/ehs215","article-title":"ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation","volume":"33","author":"Steg","year":"2012","journal-title":"Eur Heart J."},{"key":"10.1016\/j.rec.2023.03.015_bib0240","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1373\/clinchem.2009.132654","article-title":"Analytical validation of a high-sensitivity cardiac troponin T assay","volume":"56","author":"Giannitsis","year":"2010","journal-title":"Clin Chem."},{"key":"10.1016\/j.rec.2023.03.015_bib0245","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.clinbiochem.2003.11.002","article-title":"Biochemical indicators of cardiac and renal function in a healthy elderly population","volume":"37","author":"Johnston","year":"2004","journal-title":"Clin Biochem."},{"key":"10.1016\/j.rec.2023.03.015_bib0250","doi-asserted-by":"crossref","first-page":"2345","DOI":"10.1001\/archinte.163.19.2345","article-title":"Predictors of hospital mortality in the global registry of acute coronary events","volume":"163","author":"Granger","year":"2003","journal-title":"Arch Intern Med."},{"key":"10.1016\/j.rec.2023.03.015_bib0255","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1136\/bmj.38985.646481.55","article-title":"Prediction of risk of death and myocardial infarction in the six months after presentation with acute coronary syndrome: prospective multinational observational study (GRACE)","volume":"333","author":"Fox","year":"2006","journal-title":"BMJ."},{"key":"10.1016\/j.rec.2023.03.015_bib0260","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.diabres.2017.11.031","article-title":"Implications of circulating Meteorin-like (Metrnl) level in human subjects with type 2 diabetes","volume":"136","author":"Chung","year":"2018","journal-title":"Diabetes Res Clin Pract."},{"key":"10.1016\/j.rec.2023.03.015_bib0265","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1111\/febs.15301","article-title":"The myokine meteorin-like (metrnl) improves glucose tolerance in both skeletal muscle cells and mice by targeting AMPK\u03b12","volume":"287","author":"Lee","year":"2020","journal-title":"FEBS J."},{"key":"10.1016\/j.rec.2023.03.015_bib0270","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.3390\/cells8101283","article-title":"Increased Expression of Meteorin-Like Hormone in Type 2 Diabetes and Obesity and Its Association with Irisin","volume":"8","author":"Alkhairi","year":"2019","journal-title":"Cells."},{"key":"10.1016\/j.rec.2023.03.015_bib0275","first-page":"1","article-title":"A meta-analysis of the relationship between serums metrnl-like protein\/subfatin and risk of type 2 diabetes mellitus and coronary artery disease","volume":"5","author":"Ferns","year":"2021","journal-title":"Arch Physiol Biochem."},{"key":"10.1016\/j.rec.2023.03.015_bib0280","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1016\/j.amjcard.2012.06.025","article-title":"Atherosclerotic risk factors and their association with hospital mortality among patients with first myocardial infarction (from the National Registry of Myocardial Infarction)","volume":"110","author":"Canto","year":"2012","journal-title":"Am J Cardiol."},{"key":"10.1016\/j.rec.2023.03.015_bib0285","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1038\/s41401-020-0368-8","article-title":"Metrnl deficiency decreases blood HDL cholesterol and increases blood triglyceride","volume":"41","author":"Qi","year":"2020","journal-title":"Acta Pharmacol Sin."},{"key":"10.1016\/j.rec.2023.03.015_bib0290","doi-asserted-by":"crossref","first-page":"e0204180","DOI":"10.1371\/journal.pone.0204180","article-title":"Lower serum levels of Meteorin-like\/Subfatin in patients with coronary artery disease and type 2 diabetes mellitus are negatively associated with insulin resistance and inflammatory cytokines","volume":"13","author":"Dadmanesh","year":"2018","journal-title":"PLoS One."},{"key":"10.1016\/j.rec.2023.03.015_bib0295","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.diabres.2019.02.026","article-title":"Association of low serum Meteorin like (Metrnl) concentrations with worsening of glucose tolerance, impaired endothelial function and atherosclerosis","volume":"150","author":"El-Ashmawy","year":"2019","journal-title":"Diabetes Res Clin Pract."},{"key":"10.1016\/j.rec.2023.03.015_bib0300","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1111\/jcmm.13915","article-title":"Serum Metrnl is associated with the presence and severity of coronary artery disease","volume":"23","author":"Liu","year":"2019","journal-title":"J Cell Mol Med."},{"key":"10.1016\/j.rec.2023.03.015_bib0305","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.ahj.2005.11.013","article-title":"Extent of coronary artery disease as a predictor of outcomes in acute myocardial infarction complicated by heart failure, left ventricular dysfunction, or both","volume":"152","author":"Janardhanan","year":"2006","journal-title":"Am Heart J."},{"key":"10.1016\/j.rec.2023.03.015_bib0310","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1093\/eurheartj\/ehm184","article-title":"Impact of multivessel disease on reperfusion success and clinical outcomes in patients undergoing primary percutaneous coronary intervention for acute myocardial infarction","volume":"28","author":"Sorajja","year":"2007","journal-title":"Eur Heart J."},{"key":"10.1016\/j.rec.2023.03.015_bib0315","doi-asserted-by":"crossref","first-page":"2019","DOI":"10.1001\/jama.2014.15095","article-title":"Extent, location, and clinical significance of non-infarct-related coronary artery disease among patients with ST-elevation myocardial infarction","volume":"312","author":"Park","year":"2014","journal-title":"JAMA."},{"key":"10.1016\/j.rec.2023.03.015_bib0320","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1001\/jamacardio.2016.0074","article-title":"Atherosclerotic Burden and Heart Failure After Myocardial Infarction","volume":"1","author":"Gerber","year":"2016","journal-title":"JAMA Cardiol."},{"key":"10.1016\/j.rec.2023.03.015_bib0325","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.pharmthera.2018.01.001","article-title":"Inflammation following acute myocardial infarction: Multiple players, dynamic roles, and novel therapeutic opportunities","volume":"186","author":"Ong","year":"2018","journal-title":"Pharmacol Ther."},{"key":"10.1016\/j.rec.2023.03.015_bib0330","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1007\/s11886-020-01358-2","article-title":"Targeting Inflammation After Myocardial Infarction","volume":"22","author":"Mahtta","year":"2020","journal-title":"Curr Cardiol Rep."},{"key":"10.1016\/j.rec.2023.03.015_bib0335","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1016\/j.jacc.2020.01.014","article-title":"Inflammation in Heart Failure: JACC State-of-the-Art Review","volume":"75","author":"Murphy","year":"2020","journal-title":"J Am Coll Cardiol."},{"key":"10.1016\/j.rec.2023.03.015_bib0340","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1161\/CIRCULATIONAHA.106.613596","article-title":"Cardiogenic shock: current concepts and improving outcomes","volume":"117","author":"Reynolds","year":"2008","journal-title":"Circulation."},{"key":"10.1016\/j.rec.2023.03.015_bib0345","doi-asserted-by":"crossref","first-page":"3669","DOI":"10.4049\/jimmunol.1800435","article-title":"Meteorin-like\/Meteorin-\u03b2 Is a Novel Immunoregulatory Cytokine Associated with Inflammation","volume":"201","author":"Ushach","year":"2018","journal-title":"J Immunol."},{"key":"10.1016\/j.rec.2023.03.015_bib0350","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/bs.apcsb.2017.01.002","article-title":"Cardiokines as Modulators of Stress-Induced Cardiac Disorders","volume":"108","author":"Planavila","year":"2017","journal-title":"Adv Protein Chem Struct Biol."}],"container-title":["Revista Espa\u00f1ola de Cardiolog\u00eda (English Edition)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1885585723001056?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1885585723001056?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,18]],"date-time":"2024-05-18T15:44:42Z","timestamp":1716047082000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1885585723001056"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":35,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["S1885585723001056"],"URL":"https:\/\/doi.org\/10.1016\/j.rec.2023.03.015","relation":{},"ISSN":["1885-5857"],"issn-type":[{"value":"1885-5857","type":"print"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Meteorin-like protein is associated with a higher risk profile and predicts a worse outcome in patients with STEMI","name":"articletitle","label":"Article Title"},{"value":"Revista Espa\u00f1ola de Cardiolog\u00eda (English Edition)","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.rec.2023.03.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.recesp.2023.03.016","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Sociedad Espa\u00f1ola de Cardiolog\u00eda. Published by Elsevier Espa\u00f1a, S.L.U. All rights reserved.","name":"copyright","label":"Copyright"}]}}