{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T13:08:07Z","timestamp":1779109687227,"version":"3.51.4"},"reference-count":33,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Revista Espa\u00f1ola de Anestesiolog\u00eda y Reanimaci\u00f3n (English Edition)"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1016\/j.redare.2026.502107","type":"journal-article","created":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T15:07:32Z","timestamp":1776697652000},"page":"502107","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["The impact of sedation and analgesia on post-ICU syndrome: Experience from a post-critical care follow-up clinic"],"prefix":"10.1016","volume":"73","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2290-4807","authenticated-orcid":false,"given":"B.","family":"Zalba-Etayo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Vill\u00e9n-Lapuente","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.J.","family":"Ara\u00edz-Burdio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.L.","family":"Cabrerizo-Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.redare.2026.502107_bib0005","first-page":"120","article-title":"Humanizaci\u00f3n de los cuidados intensivos","volume":"30","author":"Rojas","year":"2019","journal-title":"Revista Med Clin Las Condes [Internet]"},{"key":"10.1016\/j.redare.2026.502107_bib0010","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.medin.2018.12.005","article-title":"Programa de seguimiento al alta de la unidad de cuidados intensivos","volume":"43","author":"Busico","year":"2019","journal-title":"Med Intensiva [Internet]"},{"key":"10.1016\/j.redare.2026.502107_bib0015","article-title":"Caracter\u00edsticas del s\u00edndrome post cuidado intensivo: revisi\u00f3n de alcance","volume":"23","author":"Henao-Casta\u00f1o","year":"2021","journal-title":"Investig Enferm Imagen Desarro [Internet]"},{"key":"10.1016\/j.redare.2026.502107_bib0020","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1515\/jtim-2016-0016","article-title":"Post-intensive care syndrome: an overview","volume":"5","author":"Rawal","year":"2017","journal-title":"J Transl Int Med"},{"key":"10.1016\/j.redare.2026.502107_bib0025","series-title":"Estrategias de prevenci\u00f3n y control frente a la aparici\u00f3n del s\u00edndrome Post-UCI en el paciente cr\u00edtico y la familia. Una revisi\u00f3n narrativa [trabajo de fin de grado]","author":"de la Mata Garc\u00eda-Notario","year":"2021"},{"key":"10.1016\/j.redare.2026.502107_bib0030","first-page":"39","article-title":"Efecto de una rehabilitaci\u00f3n temprana en pacientes con debilidad adquirida en la Unidad de Cuidados Intensivos","volume":"36","author":"Mart\u00ednez Cruz","year":"2022","journal-title":"Med Crit"},{"key":"10.1016\/j.redare.2026.502107_bib0035","doi-asserted-by":"crossref","first-page":"438","DOI":"10.7705\/biomedica.6947","article-title":"Disminuci\u00f3n de la debilidad muscular adquirida en una unidad de cuidados intensivos con la implementaci\u00f3n de un protocolo multicomponente: ensayo cl\u00ednico cuasiexperimental","volume":"43","author":"Giraldo","year":"2023","journal-title":"Biomedica"},{"key":"10.1016\/j.redare.2026.502107_bib0040","doi-asserted-by":"crossref","first-page":"5881","DOI":"10.3390\/jcm13195881","article-title":"Post-intensive care syndrome as a burden for patients and their caregivers: a narrative review","volume":"13","author":"Schembari","year":"2024","journal-title":"J Clin Med"},{"key":"10.1016\/j.redare.2026.502107_bib0045","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s13613-025-01429-z","article-title":"Estimated prevalence of post-intensive care cognitive impairment at short-term and long-term follow-ups: a proportional meta-analysis of observational studies","volume":"15","author":"Ho","year":"2025","journal-title":"Ann Intensive Care"},{"key":"10.1016\/j.redare.2026.502107_bib0050","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1097\/00003246-198510000-00009","article-title":"APACHE II: a severity of disease classification system","volume":"13","author":"Knaus","year":"1985","journal-title":"Crit Care Med"},{"key":"10.1016\/j.redare.2026.502107_bib0055","first-page":"141","article-title":"Monitoring sedation status over time in ICU patients: reliability and validity of the Richmond Agitation-Sedation Scale (RASS)","volume":"31","author":"Ely","year":"2003","journal-title":"Crit Care Med"},{"key":"10.1016\/j.redare.2026.502107_bib0060","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0168-8510(90)90421-9","article-title":"EuroQol\u2014a new facility for the measurement of health-related quality of life","volume":"16","year":"1990","journal-title":"Health Policy"},{"key":"10.1016\/j.redare.2026.502107_bib0065","first-page":"61","article-title":"Functional evaluation: the Barthel Index","volume":"14","author":"Mahoney","year":"1965","journal-title":"Md State Med J"},{"key":"10.1016\/j.redare.2026.502107_bib0070","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1111\/j.1532-5415.1991.tb01616.x","article-title":"The timed \u201cUp & Go\u201d: a test of basic functional mobility for frail elderly persons","volume":"39","author":"Podsiadlo","year":"1991","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.redare.2026.502107_bib0075","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1503\/cmaj.050051","article-title":"A global clinical measure of fitness and frailty in elderly people","volume":"173","author":"Rockwood","year":"2005","journal-title":"CMAJ"},{"key":"10.1016\/j.redare.2026.502107_bib0080","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1016\/S0140-6736(74)90884-8","article-title":"Measurement of pain","volume":"2","author":"Huskisson","year":"1974","journal-title":"Lancet"},{"key":"10.1016\/j.redare.2026.502107_bib0085","series-title":"The \u2018MUST\u2019 report. Nutritional screening of adults: a multidisciplinary responsibility","author":"Elia","year":"2003"},{"key":"10.1016\/j.redare.2026.502107_bib0090","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.jamda.2013.05.018","article-title":"SARC-F: a simple questionnaire to rapidly diagnose sarcopenia","volume":"14","author":"Malmstrom","year":"2013","journal-title":"J Am Med Dir Assoc"},{"key":"10.1016\/j.redare.2026.502107_bib0095","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1111\/j.1532-5415.2005.53221.x","article-title":"The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment","volume":"53","author":"Nasreddine","year":"2005","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.redare.2026.502107_bib0100","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.1600-0447.1983.tb09716.x","article-title":"The hospital anxiety and depression scale","volume":"67","author":"Zigmond","year":"1983","journal-title":"Acta Psychiatr Scand"},{"key":"10.1016\/j.redare.2026.502107_bib0105","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1111\/bcp.16031","article-title":"The risk of delirium after sedation with propofol or midazolam in intensive care unit patients","volume":"90","author":"van Gelder","year":"2024","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.redare.2026.502107_bib0110","first-page":"1330","article-title":"Sedation and delirium in critically ill patients: the role of propofol and other sedatives","volume":"195","author":"Pandharipande","year":"2017","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.redare.2026.502107_bib0115","first-page":"676","article-title":"Efficacy and safety of dexmedetomidine versus lorazepam for sedation of critically ill patients: a randomized trial","volume":"182","author":"Girard","year":"2010","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.redare.2026.502107_bib0120","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2020-045087","article-title":"Sedation strategy and ICU delirium: a multicentre, population-based propensity score-matched cohort study","volume":"11","author":"Casault","year":"2021","journal-title":"BMJ Open"},{"key":"10.1016\/j.redare.2026.502107_bib0125","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1001\/jama.2010.1553","article-title":"Long-term cognitive impairment and functional disability among survivors of severe sepsis","volume":"304","author":"Iwashyna","year":"2010","journal-title":"JAMA"},{"key":"10.1016\/j.redare.2026.502107_bib0130","doi-asserted-by":"crossref","DOI":"10.1136\/bmj-2024-079789","article-title":"Management of pain and sedation in the intensive care unit","volume":"387","author":"Boncyk","year":"2024","journal-title":"BMJ"},{"key":"10.1016\/j.redare.2026.502107_bib0135","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.redar.2023.05.008","article-title":"Efectividad de un programa de seguimiento espec\u00edfico para el manejo de los componentes mentales del s\u00edndrome poscuidados intensivos y el dolor cr\u00f3nico tras la enfermedad por coronavirus de 2019: resultados del ensayo cl\u00ednico aleatorizado \u201cPain Covid\u201d","volume":"71","author":"Ojeda","year":"2024","journal-title":"Rev Esp Anestesiol Reanim"},{"key":"10.1016\/j.redare.2026.502107_bib0140","doi-asserted-by":"crossref","first-page":"e825","DOI":"10.1097\/CCM.0000000000003299","article-title":"Clinical practice guidelines for the prevention and management of pain, agitation\/sedation, delirium, immobility, and sleep disruption in adult patients in the ICU","volume":"46","author":"Devlin","year":"2018","journal-title":"Crit Care Med"},{"key":"10.1016\/j.redare.2026.502107_bib0145","first-page":"36","article-title":"Opioid use in the intensive care unit: a focus on safety, monitoring, and prevention of adverse events","volume":"39","author":"Jasiak","year":"2019","journal-title":"Crit Care Nurse"},{"key":"10.1016\/j.redare.2026.502107_bib0150","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1056\/NEJM200005183422002","article-title":"Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation","volume":"342","author":"Kress","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.redare.2026.502107_bib0155","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1097\/CCM.0000000000004976","article-title":"Association between opioid use and delirium in critically ill adults: a cohort study","volume":"49","author":"Duprey","year":"2021","journal-title":"Crit Care Med"},{"key":"10.1016\/j.redare.2026.502107_bib0160","first-page":"1838","article-title":"Sedation practices and outcomes in the intensive care unit: a multicenter observational study","volume":"40","author":"van den Boogaard","year":"2012","journal-title":"Crit Care Med"},{"key":"10.1016\/j.redare.2026.502107_bib0165","first-page":"1225","article-title":"Early mobilization in the ICU: a systematic review","volume":"42","author":"Needham","year":"2014","journal-title":"Crit Care Med"}],"container-title":["Revista Espa\u00f1ola de Anestesiolog\u00eda y Reanimaci\u00f3n (English Edition)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2341192926000983?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2341192926000983?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T12:24:45Z","timestamp":1779107085000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2341192926000983"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":33,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["S2341192926000983"],"URL":"https:\/\/doi.org\/10.1016\/j.redare.2026.502107","relation":{},"ISSN":["2341-1929"],"issn-type":[{"value":"2341-1929","type":"print"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The impact of sedation and analgesia on post-ICU syndrome: Experience from a post-critical care follow-up clinic","name":"articletitle","label":"Article Title"},{"value":"Revista Espa\u00f1ola de Anestesiolog\u00eda y Reanimaci\u00f3n (English Edition)","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.redare.2026.502107","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.redar.2026.502107","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Espa\u00f1a, S.L.U. on behalf of Sociedad Espa\u00f1ola de Anestesiolog\u00eda, Reanimaci\u00f3n y Terap\u00e9utica del Dolor. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"502107"}}