{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T17:34:19Z","timestamp":1793122459095,"version":"4.5.0"},"reference-count":11,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Revista Espa\u00f1ola de Anestesiolog\u00eda y Reanimaci\u00f3n (English Edition)"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.redare.2026.502167","type":"journal-article","created":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T15:21:25Z","timestamp":1788362485000},"page":"502167","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Severe adverse events associated with general anesthesia with halogenated agents in patients of Venezuelan ancestry. Recommendations for clinical practice"],"prefix":"10.1016","volume":"73","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9939-3697","authenticated-orcid":false,"given":"E.","family":"M\u00e9ndez Mart\u00ednez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3047-5923","authenticated-orcid":false,"given":"C.","family":"Garc\u00eda Cebri\u00e1n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3530-5256","authenticated-orcid":false,"given":"A.M.","family":"Gonz\u00e1lez Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9344-3200","authenticated-orcid":false,"given":"P.","family":"Sanabria Carretero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4579-3027","authenticated-orcid":false,"given":"F.","family":"Munar Bauz\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8556-0434","authenticated-orcid":false,"given":"G.","family":"Alcaraz Garc\u00eda-Tejedor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0313-156X","authenticated-orcid":false,"given":"P.","family":"Gonz\u00e1lez Pizarro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-8597-5909","authenticated-orcid":false,"given":"D.","family":"M\u00e9ndez Mar\u00edn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1724-8494","authenticated-orcid":false,"given":"F.","family":"Cassinello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Encarnaci\u00f3n Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-3229-9112","authenticated-orcid":false,"given":"K.","family":"Sifontes Romero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-5494-260X","authenticated-orcid":false,"given":"M.","family":"Almena Marjalizo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8882-081X","authenticated-orcid":false,"given":"C.L.","family":"Errando Oyonarte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6518-7097","authenticated-orcid":false,"given":"F.J.","family":"Escrib\u00e0 Alepuz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Garc\u00eda Fern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.redare.2026.502167_bib0005","series-title":"Documento informativo Sociedad Espa\u00f1ola de Anestesiolog\u00eda y Reanimaci\u00f3n (SEDAR) Alerta m\u00e9dica: eventos adversos graves asociados a anestesia general con agentes halogenados en pacientes de ascendencia venezolana","year":"2026"},{"key":"10.1016\/j.redare.2026.502167_bib0010","unstructured":"Comit\u00e9 ejecutivo y comit\u00e9 cient\u00edfico de la SEDAR, Grupo de Trabajo mtND4 Anestesia Pedi\u00e1trica SEDAR. Documento informativo Sociedad Espa\u00f1ola de Anestesiolog\u00eda y Reanimaci\u00f3n (SEDAR) Alerta m\u00e9dica: Mutaci\u00f3n gen\u00e9tica en ni\u00f1os de procedencia venezolana y complicaciones anest\u00e9sicas. https:\/\/www.sedar.es\/images\/images\/site\/ACTUALIZACIONES\/2025\/SEPTIEMBRE\/Draft_V8def_v02.pdf."},{"key":"10.1016\/j.redare.2026.502167_bib0015","series-title":"Updated joint communication: Severe neurological complications and death after general anesthesia in adult and pediatric patients of Venezuelan ancestry","year":"2026"},{"key":"10.1016\/j.redare.2026.502167_bib0020","series-title":"Updated joint communication: Joint Statement on Anaesthesia-Related Mitochondrial Pharmacogenetic Risk in Individuals with Venezuelan Maternal Ancestry","year":"2026"},{"key":"10.1016\/j.redare.2026.502167_bib0025","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1097\/ALN.0000000000006029","article-title":"Effects of a mitochondrial genetic variant on sevoflurane hypersensivity","volume":"144","author":"Sanz-Pons","year":"2026","journal-title":"Anestgesiology"},{"key":"10.1016\/j.redare.2026.502167_bib0030","series-title":"Encefalopat\u00eda aguda asociada a anestesia general en un paciente adulto portador de la variante m.11232T>C en el gen MT-ND4","author":"Arranz Chamorro","year":"2026"},{"key":"10.1016\/j.redare.2026.502167_bib0035","doi-asserted-by":"crossref","DOI":"10.1097\/ALN.0000000000005935","article-title":"Potential mitochondrial pharmacogenetic susceptibility to severe neurologic events after general anesthesia: Report from the Chilean Ministry of Health","author":"Yanez Hinojosa","year":"2026","journal-title":"Anesthesiology."},{"key":"10.1016\/j.redare.2026.502167_bib0040","unstructured":"Comunicado a la opini\u00f3n p\u00fablica Comit\u00e9 de Cuidado Perioperatorio Pedi\u00e1trico Sociedad Colombiana de Anestesiolog\u00eda y Reanimaci\u00f3n (SCARE) 04\/02\/2026. https:\/\/scare.org.co\/noticias\/comunicado-comite-cuidado-perioperatorio-pediatrico\/."},{"key":"10.1016\/j.redare.2026.502167_bib0045","unstructured":"Sociedad de Anestesiolog\u00eda de Chile. Consideraciones Cl\u00ednicas frente a una variante gen\u00e9tica infrecuente asociada a complicaciones neurol\u00f3gicas severas tras anestesia general en poblaci\u00f3n con ascendencia venezolana. https:\/\/www.sachile.cl\/upfiles\/userfile\/files\/R01_v01.pdf."},{"key":"10.1016\/j.redare.2026.502167_bib0050","series-title":"Emerging Reports of Severe Neurologic Complication Following General Anesthesia in Patients with Maternal Venezuelan Ancestry","year":"2026"},{"key":"10.1016\/j.redare.2026.502167_bib0055","unstructured":"Communication conjointe \u00e0 propos d\u2019un risque pharmacog\u00e9n\u00e9tique d\u2019origine mitochondriale de complication anesth\u00e9sique chez des individus d\u2019ascendance maternelle v\u00e9n\u00e9zu\u00e9lienne. Soci\u00e9t\u00e9 Fran\u00e7aise d\u2019Anesth\u00e9sie et de R\u00e9animation (SFAR). https:\/\/sfar.org\/download\/communication-conjointe-a-propos-dun-risque-pharmacogenetique-dorigine-mitochondriale-de-complication-anesthesique-chez-des-individus-dascendance-maternelle-venezuelienne\/."}],"container-title":["Revista Espa\u00f1ola de Anestesiolog\u00eda y Reanimaci\u00f3n (English Edition)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2341192926001770?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2341192926001770?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T16:57:17Z","timestamp":1793120237000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2341192926001770"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":11,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["S2341192926001770"],"URL":"https:\/\/doi.org\/10.1016\/j.redare.2026.502167","relation":{},"ISSN":["2341-1929"],"issn-type":[{"value":"2341-1929","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Severe adverse events associated with general anesthesia with halogenated agents in patients of Venezuelan ancestry. Recommendations for clinical practice","name":"articletitle","label":"Article Title"},{"value":"Revista Espa\u00f1ola de Anestesiolog\u00eda y Reanimaci\u00f3n (English Edition)","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.redare.2026.502167","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.redar.2026.502167","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Sociedad Espa\u00f1ola de Anestesiolog\u00eda, Reanimaci\u00f3n y Terap\u00e9utica del Dolor. Published by Elsevier Espa\u00f1a, S.L.U. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"502167"}}