{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T10:39:09Z","timestamp":1790159949057,"version":"4.1.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,11,4]],"date-time":"2013-11-04T00:00:00Z","timestamp":1383523200000},"content-version":"vor","delay-in-days":307,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["GM103492"],"award-info":[{"award-number":["GM103492"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["HL078825"],"award-info":[{"award-number":["HL078825"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Redox Biology"],"published-print":{"date-parts":[[2013]]},"DOI":"10.1016\/j.redox.2013.10.011","type":"journal-article","created":{"date-parts":[[2013,11,7]],"date-time":"2013-11-07T17:19:47Z","timestamp":1383844787000},"page":"542-551","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":168,"title":["Mitochondrial fission induced by platelet-derived growth factor regulates vascular smooth muscle cell bioenergetics and cell proliferation"],"prefix":"10.1016","volume":"1","author":[{"given":"Joshua K.","family":"Salabei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bradford G.","family":"Hill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.redox.2013.10.011_bib1","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1152\/physrev.00041.2003","article-title":"Molecular regulation of vascular smooth muscle cell differentiation in development and disease","volume":"84","author":"Owens","year":"2004","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.redox.2013.10.011_bib2","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1093\/cvr\/cvs135","article-title":"The vascular smooth muscle cell in arterial pathology: a cell that can take on multiple roles","volume":"95","author":"Lacolley","year":"2012","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.redox.2013.10.011_bib3","doi-asserted-by":"crossref","first-page":"1859","DOI":"10.1161\/01.ATV.17.10.1859","article-title":"The unstable atheroma","volume":"17","author":"Lee","year":"1997","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.redox.2013.10.011_bib4","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1093\/cvr\/cvs115","article-title":"Smooth muscle cell phenotypic switching in atherosclerosis","volume":"95","author":"Gomez","year":"2012","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.redox.2013.10.011_bib5","doi-asserted-by":"crossref","first-page":"6H","DOI":"10.1016\/S0002-9149(00)01094-8","article-title":"The comparative pathobiology of atherosclerosis and restenosis","volume":"86","author":"Orford","year":"2000","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.redox.2013.10.011_bib6","doi-asserted-by":"crossref","first-page":"4","DOI":"10.2353\/ajpath.2010.090615","article-title":"Atheromas feel the pressure: biomechanical stress and atherosclerosis","volume":"177","author":"Pyle","year":"2010","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.redox.2013.10.011_bib7","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.freeradbiomed.2013.08.003","article-title":"Implications of autophagy for vascular smooth muscle cell function and plasticity","volume":"65C","author":"Salabei","year":"2013","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.redox.2013.10.011_bib8","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1126\/science.1653454","article-title":"Inhibition of neointimal smooth muscle accumulation after angioplasty by an antibody to PDGF","volume":"253","author":"Ferns","year":"1991","journal-title":"Science"},{"key":"10.1016\/j.redox.2013.10.011_bib9","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1161\/01.ATV.13.8.1218","article-title":"Role of endogenous platelet-derived growth factor in arterial smooth muscle cell migration after balloon catheter injury","volume":"13","author":"Jackson","year":"1993","journal-title":"Arterioscler. Thromb."},{"key":"10.1016\/j.redox.2013.10.011_bib10","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1080\/09537100120071013","article-title":"Modulation of smooth muscle proliferation in rat carotid artery by platelet-derived mediators and fibroblast growth factor-2","volume":"12","author":"Lewis","year":"2001","journal-title":"Platelets"},{"key":"10.1016\/j.redox.2013.10.011_bib11","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1161\/01.CIR.102.11.1330","article-title":"Bolus endovascular PDGFR-beta antisense treatment suppressed intimal hyperplasia in a rat carotid injury model","volume":"102","author":"Noiseux","year":"2000","journal-title":"Circulation"},{"key":"10.1016\/j.redox.2013.10.011_bib12","doi-asserted-by":"crossref","first-page":"E89","DOI":"10.1161\/01.ATV.20.11.e89","article-title":"Intimal hyperplasia recurs after removal of PDGF-AB and -BB inhibition in the rat carotid artery injury model","volume":"20","author":"Leppanen","year":"2000","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.redox.2013.10.011_bib13","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1096\/fasebj.11.13.9367346","article-title":"Inhibition of platelet-derived growth factor receptor tyrosine kinase inhibits vascular smooth muscle cell migration and proliferation","volume":"11","author":"Myllarniemi","year":"1997","journal-title":"FASEB J."},{"key":"10.1016\/j.redox.2013.10.011_bib14","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1161\/01.RES.88.6.630","article-title":"Weekly dosing with the platelet-derived growth factor receptor tyrosine kinase inhibitor SU9518 significantly inhibits arterial stenosis","volume":"88","author":"Yamasaki","year":"2001","journal-title":"Circ. Res."},{"key":"10.1016\/j.redox.2013.10.011_bib15","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1016\/S0022-3565(24)29489-1","article-title":"Efficacy of the novel selective platelet-derived growth factor receptor antagonist CT52923 on cellular proliferation, migration, and suppression of neointima following vascular injury","volume":"298","author":"Yu","year":"2001","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.redox.2013.10.011_bib16","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/S0002-9440(10)63457-8","article-title":"Chimera analysis supports a predominant role of PDGFRbeta in promoting smooth-muscle cell chemotaxis after arterial injury","volume":"163","author":"Buetow","year":"2003","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.redox.2013.10.011_bib17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1042\/BJ20120427","article-title":"Fulfilling the metabolic requirements for cell proliferation","volume":"446","author":"Moncada","year":"2012","journal-title":"Biochem. J."},{"key":"10.1016\/j.redox.2013.10.011_bib18","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1042\/BJ20100090","article-title":"Role of cellular bioenergetics in smooth muscle cell proliferation induced by platelet-derived growth factor","volume":"428","author":"Perez","year":"2010","journal-title":"Biochem. J."},{"key":"10.1016\/j.redox.2013.10.011_bib19","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1161\/CIRCRESAHA.111.263848","article-title":"Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension","volume":"110","author":"Marsboom","year":"2012","journal-title":"Circ. Res."},{"key":"10.1016\/j.redox.2013.10.011_bib20","doi-asserted-by":"crossref","first-page":"2630","DOI":"10.1161\/CIRCULATIONAHA.105.609008","article-title":"An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension","volume":"113","author":"Bonnet","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.redox.2013.10.011_bib21","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1002\/bies.201300011","article-title":"Mitochondrial fission-fusion as an emerging key regulator of cell proliferation and differentiation","volume":"35","author":"Mitra","year":"2013","journal-title":"Bioessays"},{"key":"10.1016\/j.redox.2013.10.011_bib22","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1042\/BJ20121344","article-title":"PDGF-mediated autophagy regulates vascular smooth muscle cell phenotype and resistance to oxidative stress","volume":"451","author":"Salabei","year":"2013","journal-title":"Biochem. J."},{"key":"10.1016\/j.redox.2013.10.011_bib23","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1042\/BJ20071063","article-title":"Unsaturated lipid peroxidation-derived aldehydes activate autophagy in vascular smooth-muscle cells","volume":"410","author":"Hill","year":"2008","journal-title":"Biochem. J."},{"key":"10.1016\/j.redox.2013.10.011_bib24","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.freeradbiomed.2012.08.014","article-title":"Utilization of fluorescent probes for the quantification and identification of subcellular proteomes and biological processes regulated by lipid peroxidation products","volume":"59","author":"Cummins","year":"2013","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.redox.2013.10.011_bib25","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.bbabio.2009.11.005","article-title":"Regulation of vascular smooth muscle cell bioenergetic function by protein glutathiolation","volume":"1797","author":"Hill","year":"2010","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.redox.2013.10.011_bib26","doi-asserted-by":"crossref","first-page":"e34465","DOI":"10.1371\/journal.pone.0034465","article-title":"Investigation of mitochondrial dysfunction by sequential microplate-based respiration measurements from intact and permeabilized neurons","volume":"7","author":"Clerc","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.redox.2013.10.011_bib27","doi-asserted-by":"crossref","first-page":"5422","DOI":"10.1073\/pnas.1303360110","article-title":"Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier","volume":"110","author":"Divakaruni","year":"2013","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.redox.2013.10.011_bib28","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.ab.2013.02.010","article-title":"Measuring oxidative phosphorylation in human skin fibroblasts","volume":"437","author":"Ye","year":"2013","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.redox.2013.10.011_bib29","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.devcel.2007.11.019","article-title":"Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax\/Bak-dependent mitochondrial outer membrane permeabilization","volume":"14","author":"Cassidy-Stone","year":"2008","journal-title":"Dev. Cell."},{"key":"10.1016\/j.redox.2013.10.011_bib30","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1038\/ncb1161","article-title":"Dysregulation of HSG triggers vascular proliferative disorders","volume":"6","author":"Chen","year":"2004","journal-title":"Nat. Cell. Biol."},{"key":"10.1016\/j.redox.2013.10.011_bib31","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/j.bbamcr.2012.08.014","article-title":"Targeting mitochondrial oxidative metabolism as an approach to treat heart failure","volume":"1833","author":"Fillmore","year":"2013","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.redox.2013.10.011_bib32","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1002\/9780470059593.ch8","article-title":"Choosing the right substrate","volume":"280","author":"Leverve","year":"2007","journal-title":"Novartis Found Symp."},{"key":"10.1016\/j.redox.2013.10.011_bib33","volume":"3","author":"Nicholls","year":"2002"},{"key":"10.1016\/j.redox.2013.10.011_bib34","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1111\/j.1467-789X.2009.00642.x","article-title":"Regulatory enzymes of mitochondrial beta-oxidation as targets for treatment of the metabolic syndrome","volume":"11","author":"Schreurs","year":"2010","journal-title":"Obes. Rev."},{"key":"10.1016\/j.redox.2013.10.011_bib35","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.redox.2012.10.003","article-title":"Oxidized lipids activate autophagy in a JNK-dependent manner by stimulating the endoplasmic reticulum stress response","volume":"1","author":"Haberzettl","year":"2013","journal-title":"Redox Biol."}],"container-title":["Redox Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213231713000803?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213231713000803?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T05:56:33Z","timestamp":1761976593000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213231713000803"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013]]}},"alternative-id":["S2213231713000803"],"URL":"https:\/\/doi.org\/10.1016\/j.redox.2013.10.011","relation":{},"ISSN":["2213-2317"],"issn-type":[{"value":"2213-2317","type":"print"}],"subject":[],"published":{"date-parts":[[2013]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mitochondrial fission induced by platelet-derived growth factor regulates vascular smooth muscle cell bioenergetics and cell proliferation","name":"articletitle","label":"Article Title"},{"value":"Redox Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.redox.2013.10.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}