{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T07:18:19Z","timestamp":1792826299963,"version":"4.5.0"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,4,1]],"date-time":"2017-04-01T00:00:00Z","timestamp":1491004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,4,1]],"date-time":"2017-04-01T00:00:00Z","timestamp":1491004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,11,2]],"date-time":"2016-11-02T00:00:00Z","timestamp":1478044800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100008333","name":"University of Alabama at Birmingham","doi-asserted-by":"publisher","award":["NIHR01-NS064090"],"award-info":[{"award-number":["NIHR01-NS064090"]}],"id":[{"id":"10.13039\/100008333","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Redox Biology"],"published-print":{"date-parts":[[2017,4]]},"DOI":"10.1016\/j.redox.2016.11.004","type":"journal-article","created":{"date-parts":[[2016,11,18]],"date-time":"2016-11-18T17:02:39Z","timestamp":1479488559000},"page":"73-81","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":252,"special_numbering":"C","title":["Inhibition of autophagy with bafilomycin and chloroquine decreases mitochondrial quality and bioenergetic function in primary neurons"],"prefix":"10.1016","volume":"11","author":[{"given":"Matthew","family":"Redmann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gloria A.","family":"Benavides","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taylor F.","family":"Berryhill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Willayat Y.","family":"Wani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaosen","family":"Ouyang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle S.","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saranya","family":"Ravi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Barnes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor M.","family":"Darley-Usmar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianhua","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.redox.2016.11.004_bib1","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.freeradbiomed.2013.05.014","article-title":"Cellular metabolic and autophagic pathways: traffic control by redox signaling","volume":"63","author":"Dodson","year":"2013","journal-title":"Free Radic. Biol. Med."},{"issue":"2","key":"10.1016\/j.redox.2016.11.004_bib2","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1042\/BJ20111451","article-title":"Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling","volume":"441","author":"Lee","year":"2012","journal-title":"Biochem. J."},{"issue":"Suppl 2","key":"10.1016\/j.redox.2016.11.004_bib3","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1038\/sj.cdd.4401765","article-title":"Autophagy: molecular machinery for self-eating","volume":"12","author":"Yorimitsu","year":"2005","journal-title":"Cell Death Differ."},{"issue":"5497","key":"10.1016\/j.redox.2016.11.004_bib4","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1126\/science.290.5497.1717","article-title":"Autophagy as a regulated pathway of cellular degradation","volume":"290","author":"Klionsky","year":"2000","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.redox.2016.11.004_bib5","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.redox.2012.11.008","article-title":"Autophagy and mitophagy in cellular damage control","volume":"1","author":"Zhang","year":"2013","journal-title":"Redox Biol."},{"key":"10.1016\/j.redox.2016.11.004_bib6","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.redox.2015.01.003","article-title":"Teaching the basics of autophagy and mitophagy to redox biologists--mechanisms and experimental approaches","volume":"4","author":"Zhang","year":"2015","journal-title":"Redox Biol."},{"issue":"6356","key":"10.1016\/j.redox.2016.11.004_bib7","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1038\/355167a0","article-title":"Inhibition by chloroquine of a novel haem polymerase enzyme activity in malaria trophozoites","volume":"355","author":"Slater","year":"1992","journal-title":"Nature"},{"issue":"8","key":"10.1016\/j.redox.2016.11.004_bib8","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/S0764-4469(98)80009-7","article-title":"Impact of chloroquine resistance on malaria mortality","volume":"321","author":"Trape","year":"1998","journal-title":"C. R. Acad. Sci. III"},{"issue":"1","key":"10.1016\/j.redox.2016.11.004_bib9","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1158\/0008-5472.CAN-12-2464","article-title":"Chloroquine in cancer therapy: a double-edged sword of autophagy","volume":"73","author":"Kimura","year":"2013","journal-title":"Cancer Res."},{"key":"10.1016\/j.redox.2016.11.004_bib10","doi-asserted-by":"crossref","first-page":"178","DOI":"10.3389\/fneur.2015.00178","article-title":"Cathepsin B is a new drug target for traumatic brain injury therapeutics: evidence for E64d as a promising lead drug candidate","volume":"6","author":"Hook","year":"2015","journal-title":"Front. Neurol."},{"issue":"2","key":"10.1016\/j.redox.2016.11.004_bib11","doi-asserted-by":"crossref","first-page":"387","DOI":"10.3233\/JAD-2011-110101","article-title":"The cysteine protease inhibitor, E64d, reduces brain amyloid-beta and improves memory deficits in Alzheimer's disease animal models by inhibiting cathepsin B, but not BACE1, beta-secretase activity","volume":"26","author":"Hook","year":"2011","journal-title":"J. Alzheimers Dis."},{"issue":"1","key":"10.1016\/j.redox.2016.11.004_bib12","doi-asserted-by":"crossref","first-page":"129","DOI":"10.3233\/JAD-131370","article-title":"Brain pyroglutamate amyloid-beta is produced by cathepsin B and is reduced by the cysteine p inhibitor E64d, representing a potential Alzheimer's disease therapeutic","volume":"41","author":"Hook","year":"2014","journal-title":"J. Alzheimers Dis."},{"issue":"4","key":"10.1016\/j.redox.2016.11.004_bib13","doi-asserted-by":"crossref","first-page":"445","DOI":"10.4161\/auto.19496","article-title":"Guidelines for the use and interpretation of assays for monitoring autophagy","volume":"8","author":"Klionsky","year":"2012","journal-title":"Autophagy"},{"issue":"4","key":"10.1016\/j.redox.2016.11.004_bib14","doi-asserted-by":"crossref","first-page":"425","DOI":"10.18632\/aging.100038","article-title":"Mitochondrial dysfunction and oxidative stress mediate the physiological impairment induced by the disruption of autophagy","volume":"1","author":"Wu","year":"2009","journal-title":"Aging"},{"issue":"21","key":"10.1016\/j.redox.2016.11.004_bib15","doi-asserted-by":"crossref","first-page":"7972","DOI":"10.1073\/pnas.85.21.7972","article-title":"Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells","volume":"85","author":"Bowman","year":"1988","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"2","key":"10.1016\/j.redox.2016.11.004_bib16","doi-asserted-by":"crossref","DOI":"10.7164\/antibiotics.37.110","article-title":"Metabolic products of microorganisms. 224. Bafilomycins, a new group of macrolide antibiotics. Production, isolation, chemical structure and biological activity","volume":"37","author":"Werner","year":"1984","journal-title":"J. Antibiot."},{"issue":"26","key":"10.1016\/j.redox.2016.11.004_bib17","doi-asserted-by":"crossref","first-page":"17707","DOI":"10.1016\/S0021-9258(19)47429-2","article-title":"Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells","volume":"266","author":"Yoshimori","year":"1991","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.redox.2016.11.004_bib18","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1247\/csf.23.33","article-title":"Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells","volume":"23","author":"Yamamoto","year":"1998","journal-title":"Cell Struct. Funct."},{"issue":"7","key":"10.1016\/j.redox.2016.11.004_bib19","doi-asserted-by":"crossref","first-page":"849","DOI":"10.4161\/auto.6845","article-title":"Does bafilomycin A1 block the fusion of autophagosomes with lysosomes?","volume":"4","author":"Klionsky","year":"2008","journal-title":"Autophagy"},{"issue":"4","key":"10.1016\/j.redox.2016.11.004_bib20","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1007\/s10863-007-9095-9","article-title":"Bafilomycin A1 is a potassium ionophore that impairs mitochondrial functions","volume":"39","author":"Teplova","year":"2007","journal-title":"J. Bioenerg. Biomembr."},{"issue":"5","key":"10.1016\/j.redox.2016.11.004_bib21","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1007\/s00018-010-0502-8","article-title":"Bafilomycin A1 activates respiration of neuronal cells via uncoupling associated with flickering depolarization of mitochondria","volume":"68","author":"Zhdanov","year":"2011","journal-title":"Cell Mol. Life Sci."},{"issue":"4","key":"10.1016\/j.redox.2016.11.004_bib22","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/0166-3542(95)00040-S","article-title":"Inhibitory effect of bafilomycin A1, a specific inhibitor of vacuolar-type proton pump, on the growth of influenza A and B viruses in MDCK cells","volume":"27","author":"Ochiai","year":"1995","journal-title":"Antivir. Res."},{"issue":"3","key":"10.1016\/j.redox.2016.11.004_bib23","doi-asserted-by":"crossref","first-page":"L270","DOI":"10.1152\/ajplung.00011.2014","article-title":"Suppression of influenza A virus replication in human lung epithelial cells by noncytotoxic concentrations bafilomycin A1","volume":"308","author":"Yeganeh","year":"2015","journal-title":"Am. J. Physiol. Lung Cell. Mol. Physiol."},{"issue":"3","key":"10.1016\/j.redox.2016.11.004_bib24","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/j.taap.2013.07.024","article-title":"Azathioprine desensitizes liver cancer cells to insulin-like growth factor 1 and causes apoptosis when it is combined with bafilomycin A1","volume":"272","author":"Hernandez-Breijo","year":"2013","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"3","key":"10.1016\/j.redox.2016.11.004_bib25","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1002\/(SICI)1096-9896(199807)185:3<324::AID-PATH72>3.0.CO;2-9","article-title":"Bafilomycin A1 induces apoptosis in the human pancreatic cancer cell line Capan-1","volume":"185","author":"Ohta","year":"1998","journal-title":"J. Pathol."},{"issue":"6","key":"10.1016\/j.redox.2016.11.004_bib26","doi-asserted-by":"crossref","first-page":"1856","DOI":"10.1124\/mol.106.028076","article-title":"Bafilomycin induces the p21-mediated growth inhibition of cancer cells under hypoxic conditions by expressing hypoxia-inducible factor-1alpha","volume":"70","author":"Lim","year":"2006","journal-title":"Mol. Pharmacol."},{"issue":"5332","key":"10.1016\/j.redox.2016.11.004_bib27","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1038\/235050a0","article-title":"Lysosomes, pH and the anti-malarial action of chloroquine","volume":"235","author":"Homewood","year":"1972","journal-title":"Nature"},{"key":"10.1016\/j.redox.2016.11.004_bib28","doi-asserted-by":"crossref","first-page":"7","DOI":"10.14814\/phy2.12413","article-title":"High-dose chloroquine is metabolically cardiotoxic by inducing lysosomes and mitochondria dysfunction in a rat model of pressure overload hypertrophy","volume":"3","author":"Chaanine","year":"2015","journal-title":"Physiol. Rep."},{"key":"10.1016\/j.redox.2016.11.004_bib29","series-title":"Mitochondrial Dysfunction in Neurodegenerative Disorders","first-page":"95","author":"Zhang","year":"2012"},{"issue":"1","key":"10.1016\/j.redox.2016.11.004_bib30","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1042\/BST20120231","article-title":"Convergent mechanisms for dysregulation of mitochondrial quality control in metabolic disease: implications for mitochondrial therapeutics","volume":"41","author":"Mitchell","year":"2013","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.redox.2016.11.004_bib31","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.biocel.2014.05.010","article-title":"Mitophagy mechanisms and role in human diseases","volume":"53","author":"Redmann","year":"2014","journal-title":"Int. J. Biochem. Cell Biol."},{"issue":"12","key":"10.1016\/j.redox.2016.11.004_bib32","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1515\/hsz-2012-0198","article-title":"Integration of cellular bioenergetics with mitochondrial quality control and autophagy","volume":"393","author":"Hill","year":"2012","journal-title":"Biol. Chem."},{"issue":"1","key":"10.1016\/j.redox.2016.11.004_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1097-2765(04)00179-0","article-title":"Mitochondrial signaling: the retrograde response","volume":"14","author":"Butow","year":"2004","journal-title":"Mol. Cell."},{"issue":"1\u20132","key":"10.1016\/j.redox.2016.11.004_bib34","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1023\/B:MCBI.0000038228.85494.3b","article-title":"Mitochondrial signaling pathways: a receiver\/integrator organelle","volume":"262","author":"Goldenthal","year":"2004","journal-title":"Mol. Cell. Biochem."},{"issue":"1","key":"10.1016\/j.redox.2016.11.004_bib35","first-page":"15","article-title":"Molecular signaling in death receptor and mitochondrial pathways of apoptosis (Review)","volume":"22","author":"Gupta","year":"2003","journal-title":"Int. J. Oncol."},{"issue":"6","key":"10.1016\/j.redox.2016.11.004_bib36","doi-asserted-by":"crossref","first-page":"e66835","DOI":"10.1371\/journal.pone.0066835","article-title":"Developmental exposure to second-hand smoke increases adult atherogenesis and alters mitochondrial DNA copy number and deletions in apoE(-\/-) mice","volume":"8","author":"Fetterman","year":"2013","journal-title":"PloS One"},{"issue":"7","key":"10.1016\/j.redox.2016.11.004_bib37","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1038\/nmeth.2089","article-title":"NIH image to ImageJ: 25 years of image analysis","volume":"9","author":"Schneider","year":"2012","journal-title":"Nat. Methods"},{"key":"10.1016\/j.redox.2016.11.004_bib38","doi-asserted-by":"crossref","DOI":"10.1111\/jnc.12844","article-title":"Bioenergetic adaptation in response to autophagy regulators during rotenone exposure","author":"Giordano","year":"2014","journal-title":"J. Neurochem."},{"issue":"6","key":"10.1016\/j.redox.2016.11.004_bib39","doi-asserted-by":"crossref","first-page":"986","DOI":"10.4161\/auto.28390","article-title":"The role of GABARAPL1\/GEC1 in autophagic flux and mitochondrial quality control in MDA-MB-436 breast cancer cells","volume":"10","author":"Boyer-Guittaut","year":"2014","journal-title":"Autophagy"},{"key":"10.1016\/j.redox.2016.11.004_bib40","first-page":"159160","article-title":"Mitochondrial contribution to Parkinson's disease pathogenesis","volume":"2011","author":"Schapira","year":"2011","journal-title":"Park. Dis."},{"issue":"7","key":"10.1016\/j.redox.2016.11.004_bib41","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1161\/hc0702.103977","article-title":"Cigarette smoke exposure and hypercholesterolemia increase mitochondrial damage in cardiovascular tissues","volume":"105","author":"Knight-Lozano","year":"2002","journal-title":"Circulation"},{"issue":"9","key":"10.1016\/j.redox.2016.11.004_bib42","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1016\/j.freeradbiomed.2011.08.005","article-title":"Assessing bioenergetic function in response to oxidative stress by metabolic profiling","volume":"51","author":"Dranka","year":"2011","journal-title":"Free Radic. Biol. Med."},{"issue":"2","key":"10.1016\/j.redox.2016.11.004_bib43","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1038\/nprot.2014.018","article-title":"Comprehensive measurement of respiratory activity in permeabilized cells using extracellular flux analysis","volume":"9","author":"Salabei","year":"2014","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.redox.2016.11.004_bib44","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.redox.2016.01.002","article-title":"Mitochondrial thiol modification by a targeted electrophile inhibits metabolism in breast adenocarcinoma cells by inhibiting enzyme activity and protein levels","volume":"8","author":"Smith","year":"2016","journal-title":"Redox Biol."},{"issue":"6","key":"10.1016\/j.redox.2016.11.004_bib45","doi-asserted-by":"crossref","first-page":"542","DOI":"10.4161\/auto.4600","article-title":"How to interpret LC3 immunoblotting","volume":"3","author":"Mizushima","year":"2007","journal-title":"Autophagy"},{"issue":"21","key":"10.1016\/j.redox.2016.11.004_bib46","doi-asserted-by":"crossref","first-page":"5720","DOI":"10.1093\/emboj\/19.21.5720","article-title":"LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing","volume":"19","author":"Kabeya","year":"2000","journal-title":"EMBO J."},{"key":"10.1016\/j.redox.2016.11.004_bib47","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1016\/j.freeradbiomed.2013.09.006","article-title":"Inhibition of autophagy and glycolysis by nitric oxide during hypoxia-reoxygenation impairs cellular bioenergetics and promotes cell death in primary neurons","volume":"65","author":"Benavides","year":"2013","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.redox.2016.11.004_bib48","doi-asserted-by":"crossref","first-page":"12","DOI":"10.4161\/auto.26094","article-title":"Inhibition of glycolysis attenuates 4-hydroxynonenal-dependent autophagy and exacerbates apoptosis in differentiated SH-SY5Y neuroblastoma cells","volume":"9","author":"Dodson","year":"2013","journal-title":"Autophagy"},{"issue":"2","key":"10.1016\/j.redox.2016.11.004_bib49","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.bj.2015.10.002","article-title":"Metabolic, autophagic, and mitophagic activities in cancer initiation and progression","volume":"39","author":"Hjelmeland","year":"2016","journal-title":"Biomed. J."},{"issue":"2","key":"10.1016\/j.redox.2016.11.004_bib50","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1042\/BJ20130414","article-title":"Bioenergetic and autophagic control by Sirt3 in response to nutrient deprivation in mouse embryonic fibroblasts","volume":"454","author":"Liang","year":"2013","journal-title":"Biochem. J."},{"issue":"2","key":"10.1016\/j.redox.2016.11.004_bib51","doi-asserted-by":"crossref","first-page":"150","DOI":"10.14336\/AD.2015.0820","article-title":"The role of autophagy, mitophagy and lysosomal functions in modulating bioenergetics and survival in the context of redox and proteotoxic damage: implications for neurodegenerative diseases","volume":"7","author":"Redmann","year":"2016","journal-title":"Aging Dis."},{"issue":"7341","key":"10.1016\/j.redox.2016.11.004_bib52","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1038\/nature09922","article-title":"Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease","volume":"472","author":"Wang","year":"2011","journal-title":"Nature"},{"issue":"9","key":"10.1016\/j.redox.2016.11.004_bib53","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1161\/ATVBAHA.109.185645","article-title":"Targeted metabolomic evaluation of arginine methylation and cardiovascular risks: potential mechanisms beyond nitric oxide synthase inhibition","volume":"29","author":"Wang","year":"2009","journal-title":"Arterioscler Thromb. Vasc. Biol."},{"issue":"7527","key":"10.1016\/j.redox.2016.11.004_bib54","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1038\/nature13909","article-title":"Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS","volume":"515","author":"Chouchani","year":"2014","journal-title":"Nature"}],"container-title":["Redox Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213231716303111?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213231716303111?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T13:18:49Z","timestamp":1762607929000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213231716303111"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4]]},"references-count":54,"alternative-id":["S2213231716303111"],"URL":"https:\/\/doi.org\/10.1016\/j.redox.2016.11.004","relation":{},"ISSN":["2213-2317"],"issn-type":[{"value":"2213-2317","type":"print"}],"subject":[],"published":{"date-parts":[[2017,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Inhibition of autophagy with bafilomycin and chloroquine decreases mitochondrial quality and bioenergetic function in primary neurons","name":"articletitle","label":"Article Title"},{"value":"Redox Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.redox.2016.11.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}