{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T16:05:01Z","timestamp":1784909101658,"version":"3.55.0"},"reference-count":73,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,6,19]],"date-time":"2020-06-19T00:00:00Z","timestamp":1592524800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000646","name":"Japan Society for the Promotion of Science London","doi-asserted-by":"publisher","award":["JP17H04064"],"award-info":[{"award-number":["JP17H04064"]}],"id":[{"id":"10.13039\/501100000646","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002241","name":"Japan Science and Technology Agency","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002241","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP18J13646"],"award-info":[{"award-number":["JP18J13646"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP19H05462"],"award-info":[{"award-number":["JP19H05462"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP20H05502"],"award-info":[{"award-number":["JP20H05502"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003382","name":"Core Research for Evolutional Science and Technology","doi-asserted-by":"publisher","award":["JPMJCR19H4"],"award-info":[{"award-number":["JPMJCR19H4"]}],"id":[{"id":"10.13039\/501100003382","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Redox Biology"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1016\/j.redox.2020.101616","type":"journal-article","created":{"date-parts":[[2020,6,23]],"date-time":"2020-06-23T21:17:08Z","timestamp":1592947028000},"page":"101616","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"special_numbering":"C","title":["Asbestos conceives Fe(II)-dependent mutagenic stromal milieu through ceaseless macrophage ferroptosis and \u03b2-catenin induction in mesothelium"],"prefix":"10.1016","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5310-9630","authenticated-orcid":false,"given":"Fumiya","family":"Ito","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Izumi","family":"Yanatori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6460-029X","authenticated-orcid":false,"given":"Yuki","family":"Maeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0013-0481","authenticated-orcid":false,"given":"Kenta","family":"Nimura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoki","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tasuku","family":"Hirayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideko","family":"Nagasawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norihiko","family":"Kohyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasumasa","family":"Okazaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinya","family":"Akatsuka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinya","family":"Toyokuni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.redox.2020.101616_bib1","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.freeradbiomed.2018.07.023","article-title":"Iron from a geochemical viewpoint. Understanding toxicity\/pathogenicity mechanisms in iron-bearing minerals with a special attention to mineral fibers","volume":"133","author":"Gualtieri","year":"2019","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.redox.2020.101616_bib2","series-title":"IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. A Review of Human Carcinogens; Part C: Arsenic, Metals, Fibres, and Dusts, Lyon, France","first-page":"219","article-title":"Asbestos (chrysotile, amosite, crocidolite, tremolite, actinolite, and anthophyllite)","author":"WHO","year":"2012"},{"issue":"3","key":"10.1016\/j.redox.2020.101616_bib3","doi-asserted-by":"crossref","first-page":"531","DOI":"10.3390\/ijerph15030531","article-title":"Trends and the economic effect of asbestos bans and decline in asbestos consumption and production worldwide","volume":"15","author":"Allen","year":"2018","journal-title":"Int. J. Environ. Res. Publ. Health"},{"key":"10.1016\/j.redox.2020.101616_bib4","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.freeradbiomed.2018.10.401","article-title":"Iron addiction with ferroptosis-resistance in asbestos-induced mesothelial carcinogenesis: toward the era of mesothelioma prevention","volume":"133","author":"Toyokuni","year":"2019","journal-title":"Free Radic. Biol. Med."},{"issue":"1-2","key":"10.1016\/j.redox.2020.101616_bib5","first-page":"1","article-title":"Mechanisms of asbestos-induced carcinogenesis","volume":"71","author":"Toyokuni","year":"2009","journal-title":"Nagoya J. Med. Sci."},{"issue":"5521","key":"10.1016\/j.redox.2020.101616_bib6","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1038\/257056a0","article-title":"Induction of chromosome changes in Chinese hamster cells by exposure to asbestos fibres","volume":"257","author":"Sincock","year":"1975","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.redox.2020.101616_bib7","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/0165-1218(80)90157-3","article-title":"The genetic-effects of crocidolite asbestos - comparison of chromosome-abnormalities and sister-chromatid exchanges","volume":"79","author":"Pricejones","year":"1980","journal-title":"Mutat. Res."},{"key":"10.1016\/j.redox.2020.101616_bib8","doi-asserted-by":"crossref","first-page":"2142","DOI":"10.1111\/j.1349-7006.2008.00934.x","article-title":"Characteristics and modifying factors of asbestos-induced oxidative DNA damage","volume":"99","author":"Jiang","year":"2008","journal-title":"Cancer. Sci."},{"issue":"2","key":"10.1016\/j.redox.2020.101616_bib9","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/BF00917586","article-title":"Increased release of hydrogen peroxide and superoxide anion from asbestos-primed macrophages. Effect of hydrogen peroxide on the functional activity of alpha 1-protease inhibitor","volume":"9","author":"Donaldson","year":"1985","journal-title":"Inflammation"},{"issue":"5876","key":"10.1016\/j.redox.2020.101616_bib10","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1126\/science.1156995","article-title":"Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica","volume":"320","author":"Dostert","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.redox.2020.101616_bib11","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/1743-8977-7-5","article-title":"Asbestos, carbon nanotubes and the pleural mesothelium: a review of the hypothesis regarding the role of long fibre retention in the parietal pleura, inflammation and mesothelioma","volume":"7","author":"Donaldson","year":"2010","journal-title":"Part. Fibre Toxicol."},{"issue":"1","key":"10.1016\/j.redox.2020.101616_bib12","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/j.1349-7006.2008.01001.x","article-title":"Role of iron in carcinogenesis: cancer as a ferrotoxic disease","volume":"100","author":"Toyokuni","year":"2009","journal-title":"Cancer. Sci."},{"key":"10.1016\/j.redox.2020.101616_bib13","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1158\/1940-6207.CAPR-13-0244","article-title":"Deferasirox induces mesenchymal-epithelial transition in crocidolite-induced mesothelial carcinogenesis in rats","volume":"6","author":"Nagai","year":"2013","journal-title":"Cancer. Prev. Res."},{"issue":"2","key":"10.1016\/j.redox.2020.101616_bib14","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1111\/cas.13460","article-title":"Phlebotomy as a preventive measure for crocidolite-induced mesothelioma in male rats","volume":"109","author":"Ohara","year":"2018","journal-title":"Cancer. Sci."},{"key":"10.1016\/j.redox.2020.101616_bib15","series-title":"Pathology of Asbestos-Associated Diseases","year":"2014"},{"key":"10.1016\/j.redox.2020.101616_bib16","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1038\/bjc.1989.344","article-title":"Induction of mesothelioma by intraperitoneal injections of ferric saccharate in male Wistar rats","volume":"60","author":"Okada","year":"1989","journal-title":"Br. J. Cancer."},{"key":"10.1016\/j.redox.2020.101616_bib17","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1038\/labinvest.2009.140","article-title":"Homozygous deletion of CDKN2A\/2B is a hallmark of iron-induced high-grade rat mesothelioma","volume":"90","author":"Hu","year":"2010","journal-title":"Lab. Invest."},{"key":"10.1016\/j.redox.2020.101616_bib18","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1111\/pin.12396","article-title":"The origin and future of oxidative stress pathology: from the recognition of carcinogenesis as an iron addiction with ferroptosis resistance to non-thermal plasma therapy","volume":"66","author":"Toyokuni","year":"2016","journal-title":"Pathol. Int."},{"issue":"2","key":"10.1016\/j.redox.2020.101616_bib19","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/S0002-9440(10)64860-2","article-title":"Specific allelic loss of p16 (INK4A) tumor suppressor gene after weeks of iron-mediated oxidative damage during rat renal carcinogenesis","volume":"160","author":"Hiroyasu","year":"2002","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.redox.2020.101616_bib20","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1111\/j.1349-7006.1995.tb03308.x","article-title":"Low incidence of point mutations in H-, K- and N-ras oncogenes and p53 tumor suppressor gene in renal cell carcinoma and peritoneal mesothelioma of Wistar rats induced by ferric nitrilotriacetate","volume":"86","author":"Nishiyama","year":"1995","journal-title":"Jpn. J. Cancer. Res."},{"issue":"8","key":"10.1016\/j.redox.2020.101616_bib21","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0043403","article-title":"Fenton reaction induced cancer in wild type rats recapitulates genomic alterations observed in human cancer","volume":"7","author":"Akatsuka","year":"2012","journal-title":"PLoS One"},{"issue":"7-8","key":"10.1016\/j.redox.2020.101616_bib22","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1089\/ars.2006.8.1373","article-title":"Novel aspects of oxidative stress-associated carcinogenesis","volume":"8","author":"Toyokuni","year":"2006","journal-title":"Antioxidants Redox Signal."},{"key":"10.1016\/j.redox.2020.101616_bib23","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/j.freeradbiomed.2017.04.024","article-title":"Iron and thiol redox signaling in cancer: an exquisite balance to escape ferroptosis","volume":"108","author":"Toyokuni","year":"2017","journal-title":"Free Radic. Biol. Med."},{"issue":"4","key":"10.1016\/j.redox.2020.101616_bib24","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0018828","article-title":"Losses of both products of the Cdkn2a\/Arf locus contribute to asbestos-induced mesothelioma development and cooperate to accelerate tumorigenesis","volume":"6","author":"Altomare","year":"2011","journal-title":"PLoS One"},{"issue":"7","key":"10.1016\/j.redox.2020.101616_bib25","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1038\/ng.855","article-title":"The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma","volume":"43","author":"Bott","year":"2011","journal-title":"Nat. Genet."},{"issue":"2","key":"10.1016\/j.redox.2020.101616_bib26","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1158\/0008-5472.CAN-14-1008","article-title":"Whole-exome sequencing reveals frequent genetic alterations in BAP1, NF2, CDKN2A, and CUL1 in malignant pleural mesothelioma","volume":"75","author":"Guo","year":"2015","journal-title":"Cancer. Res."},{"issue":"4","key":"10.1016\/j.redox.2020.101616_bib27","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1038\/ng.3520","article-title":"Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations","volume":"48","author":"Bueno","year":"2016","journal-title":"Nat. Genet."},{"issue":"12","key":"10.1016\/j.redox.2020.101616_bib28","doi-asserted-by":"crossref","first-page":"1548","DOI":"10.1158\/2159-8290.CD-18-0804","article-title":"Integrative molecular characterization of malignant pleural mesothelioma","volume":"8","author":"Hmeljak","year":"2018","journal-title":"Cancer. Discov."},{"issue":"10","key":"10.1016\/j.redox.2020.101616_bib29","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1111\/pin.12453","article-title":"BAP1 immunohistochemistry and p16 FISH results in combination provide higher confidence in malignant pleural mesothelioma diagnosis: ROC analysis of the two tests","volume":"66","author":"Hida","year":"2016","journal-title":"Pathol. Int."},{"key":"10.1016\/j.redox.2020.101616_bib30","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1016\/j.jtho.2018.04.023","article-title":"New insights on diagnostic reproducibility of biphasic mesotheliomas: a multi-institutional evaluation by the international mesothelioma panel from the MESOPATH reference center","volume":"13","author":"Galateau Salle","year":"2018","journal-title":"J. Thorac. Oncol."},{"key":"10.1016\/j.redox.2020.101616_bib31","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1002\/path.4075","article-title":"Iron overload signature in chrysotile-induced malignant mesothelioma","volume":"228","author":"Jiang","year":"2012","journal-title":"J. Pathol."},{"issue":"2","key":"10.1016\/j.redox.2020.101616_bib32","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.cell.2017.09.021","article-title":"Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease","volume":"171","author":"Stockwell","year":"2017","journal-title":"Cell"},{"issue":"3","key":"10.1016\/j.redox.2020.101616_bib33","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1038\/s41418-017-0012-4","article-title":"Molecular mechanisms of cell death: recommendations of the nomenclature committee on cell death 2018","volume":"25","author":"Galluzzi","year":"2018","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.redox.2020.101616_bib34","first-page":"149","article-title":"Rat model demonstrates a high risk of tremolite but a low risk of anthophyllite for mesothelial carcinogenesis","volume":"76","author":"Aierken","year":"2014","journal-title":"Nagoya J. Med. Sci."},{"issue":"2","key":"10.1016\/j.redox.2020.101616_bib35","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1159\/000063801","article-title":"Increased expression of dipeptidyl peptidase IV in human mesothelial cells by malignant ascites from ovarian carcinoma patients","volume":"63","author":"Kajiyama","year":"2002","journal-title":"Oncology-Basel"},{"issue":"3","key":"10.1016\/j.redox.2020.101616_bib36","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.cell.2007.12.033","article-title":"Visualizing spatiotemporal dynamics of multicellular cell-cycle progression","volume":"132","author":"Sakaue-Sawano","year":"2008","journal-title":"Cell"},{"issue":"3","key":"10.1016\/j.redox.2020.101616_bib37","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1038\/ng1180","article-title":"PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes","volume":"34","author":"Mootha","year":"2003","journal-title":"Nat. Genet."},{"issue":"43","key":"10.1016\/j.redox.2020.101616_bib38","doi-asserted-by":"crossref","first-page":"15545","DOI":"10.1073\/pnas.0506580102","article-title":"Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles","volume":"102","author":"Subramanian","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"12","key":"10.1016\/j.redox.2020.101616_bib39","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.it.2004.09.015","article-title":"The chemokine system in diverse forms of macrophage activation and polarization","volume":"25","author":"Mantovani","year":"2004","journal-title":"Trends Immunol."},{"issue":"26","key":"10.1016\/j.redox.2020.101616_bib40","doi-asserted-by":"crossref","first-page":"21816","DOI":"10.1074\/jbc.M111.327031","article-title":"Identifying functional MicroRNAs in macrophages with polarized phenotypes","volume":"287","author":"Graff","year":"2012","journal-title":"J. Biol. Chem."},{"issue":"4","key":"10.1016\/j.redox.2020.101616_bib41","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/j.bbrc.2016.06.003","article-title":"Contrasting intra- and extracellular distribution of catalytic ferrous iron in ovalbumin-induced peritonitis","volume":"476","author":"Ito","year":"2016","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.redox.2020.101616_bib42","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1039\/c2sc21649c","article-title":"A highly selective turn-on fluorescent probe fro iron(II) to visualize labile iron in living cells","volume":"4","author":"Hirayama","year":"2013","journal-title":"Chem. Sci."},{"issue":"7","key":"10.1016\/j.redox.2020.101616_bib43","doi-asserted-by":"crossref","first-page":"4858","DOI":"10.1039\/C6SC05457A","article-title":"A universal fluorogenic switch for Fe(ii) ion based on N-oxide chemistry permits the visualization of intracellular redox equilibrium shift towards labile iron in hypoxic tumor cells","volume":"8","author":"Hirayama","year":"2017","journal-title":"Chem. Sci."},{"key":"10.1016\/j.redox.2020.101616_bib44","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.freeradbiomed.2018.07.004","article-title":"Fluorescent probes for the detection of catalytic Fe(II) ion","volume":"133","author":"Hirayama","year":"2019","journal-title":"Free Radic. Biol. Med."},{"issue":"1","key":"10.1016\/j.redox.2020.101616_bib45","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1038\/nprot.2006.4","article-title":"Tricine-SDS-PAGE","volume":"1","author":"Schagger","year":"2006","journal-title":"Nat. Protoc."},{"issue":"10","key":"10.1016\/j.redox.2020.101616_bib46","doi-asserted-by":"crossref","first-page":"3002","DOI":"10.1073\/pnas.1420024112","article-title":"Multicolor CRISPR labeling of chromosomal loci in human cells","volume":"112","author":"Ma","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.redox.2020.101616_bib47","doi-asserted-by":"crossref","first-page":"2616","DOI":"10.1073\/pnas.91.7.2616","article-title":"Formation of 4-hydroxy-2-nonenal-modified proteins in the renal proximal tubules of rats treated with a renal carcinogen, ferric nitrilotriacetate","volume":"91","author":"Toyokuni","year":"1994","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"4","key":"10.1016\/j.redox.2020.101616_bib48","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/S0163-7827(03)00014-6","article-title":"4-Hydroxy-2-nonenal: a product and mediator of oxidative stress","volume":"42","author":"Uchida","year":"2003","journal-title":"Prog. Lipid Res."},{"key":"10.1016\/j.redox.2020.101616_bib49","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1016\/S0891-5849(96)00489-3","article-title":"Induction of a wide range of C2-12 aldehydes and C7-12 acyloins in the kidney of Wistar rats after treatment with a renal carcinogen, ferric nitrilotriacetate","volume":"22","author":"Toyokuni","year":"1997","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.redox.2020.101616_bib50","doi-asserted-by":"crossref","first-page":"514","DOI":"10.3389\/fimmu.2014.00514","article-title":"From monocytes to M1\/M2 macrophages: phenotypical vs. Functional differentiation","volume":"5","author":"Italiani","year":"2014","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.redox.2020.101616_bib51","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1152\/physrev.00044.2005","article-title":"The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology","volume":"87","author":"Bedard","year":"2007","journal-title":"Physiol. Rev."},{"issue":"Pt 9","key":"10.1016\/j.redox.2020.101616_bib52","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.1242\/jcs.091181","article-title":"Lysosomal cell death at a glance","volume":"126","author":"Aits","year":"2013","journal-title":"J. Cell Sci."},{"issue":"2","key":"10.1016\/j.redox.2020.101616_bib53","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1038\/nrm3737","article-title":"Regulated necrosis: the expanding network of non-apoptotic cell death pathways","volume":"15","author":"Vanden Berghe","year":"2014","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"1","key":"10.1016\/j.redox.2020.101616_bib54","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.cell.2012.03.003","article-title":"MYC on the path to cancer","volume":"149","author":"Dang","year":"2012","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.redox.2020.101616_bib55","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1159\/000339613","article-title":"Wound repair and regeneration","volume":"49","author":"Reinke","year":"2012","journal-title":"Eur. Surg. Res."},{"issue":"1","key":"10.1016\/j.redox.2020.101616_bib56","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1161\/01.ATV.0000097769.47306.12","article-title":"Regulation of superoxide anion production by NADPH oxidase in monocytes\/macrophages: contributions to atherosclerosis","volume":"24","author":"Cathcart","year":"2004","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"2","key":"10.1016\/j.redox.2020.101616_bib57","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1161\/CIRCRESAHA.108.181040","article-title":"Macrophages generate reactive oxygen species in response to minimally oxidized low-density lipoprotein: toll-like receptor 4- and spleen tyrosine kinase-dependent activation of NADPH oxidase 2","volume":"104","author":"Bae","year":"2009","journal-title":"Circ. Res."},{"key":"10.1016\/j.redox.2020.101616_bib58","first-page":"365","article-title":"Quantitative immunohistochemical determination of 8-hydroxy-2'-deoxyguanosine by a monoclonal antibody N45.1: its application to ferric nitrilotriacetate-induced renal carcinogenesis model","volume":"76","author":"Toyokuni","year":"1997","journal-title":"Lab. Invest."},{"issue":"8","key":"10.1016\/j.redox.2020.101616_bib59","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1111\/j.1440-1827.2007.02127.x","article-title":"Pathological investigation of oxidative stress in the post-genomic era","volume":"57","author":"Toyokuni","year":"2007","journal-title":"Pathol. Int."},{"issue":"4","key":"10.1016\/j.redox.2020.101616_bib60","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/j.cell.2017.01.002","article-title":"Endogenous DNA damage as a source of genomic instability in cancer","volume":"168","author":"Tubbs","year":"2017","journal-title":"Cell"},{"issue":"6","key":"10.1016\/j.redox.2020.101616_bib61","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1016\/j.cell.2012.05.002","article-title":"Wnt signaling through inhibition of beta-catenin degradation in an intact Axin1 complex","volume":"149","author":"Li","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.redox.2020.101616_bib62","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.2353\/ajpath.2006.051280","article-title":"Contrasting genome-wide distribution of 8-hydroxyguanine and acrolein-modified adenine during oxidative stress-induced renal carcinogenesis","volume":"169","author":"Akatsuka","year":"2006","journal-title":"Am. J. Pathol."},{"issue":"7156","key":"10.1016\/j.redox.2020.101616_bib63","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1038\/nature06084","article-title":"p15(Ink4b) is a critical tumour suppressor in the absence of p16(Ink4a)","volume":"448","author":"Krimpenfort","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.redox.2020.101616_bib64","article-title":"Induction of gamma-glutamyltransferase activity and consequent prooxidant reactions in human macrophages exposed to crocidolite asbestos","author":"Corti","year":"2019","journal-title":"Toxicol. Sci."},{"issue":"5","key":"10.1016\/j.redox.2020.101616_bib65","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1038\/s41590-020-0654-0","article-title":"Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation","volume":"21","author":"Mendiola","year":"2020","journal-title":"Nat. Immunol."},{"issue":"28","key":"10.1016\/j.redox.2020.101616_bib66","doi-asserted-by":"crossref","first-page":"12611","DOI":"10.1073\/pnas.1006542107","article-title":"Programmed necrosis induced by asbestos in human mesothelial cells causes high-mobility group box 1 protein release and resultant inflammation","volume":"107","author":"Yang","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.redox.2020.101616_bib67","doi-asserted-by":"crossref","first-page":"2393","DOI":"10.1038\/s41467-018-04700-z","article-title":"Single-walled carbon-nanohorns improve biocompatibility over nanotubes by triggering less protein-initiated pyroptosis and apoptosis in macrophages","volume":"9","author":"He","year":"2018","journal-title":"Nat. Commun."},{"issue":"3","key":"10.1016\/j.redox.2020.101616_bib68","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.immuni.2016.02.016","article-title":"Macrophages and iron metabolism","volume":"44","author":"Soares","year":"2016","journal-title":"Immunity"},{"issue":"5","key":"10.1016\/j.redox.2020.101616_bib69","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1038\/nrc3495","article-title":"Iron and cancer: more ore to be mined","volume":"13","author":"Torti","year":"2013","journal-title":"Nat. Rev. Cancer."},{"key":"10.1016\/j.redox.2020.101616_bib70","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1002\/path.4377","article-title":"Connective tissue growth factor and \u03b2-catenin constitute an autocrine loop for activation in rat sarcomatoid mesothelioma","volume":"233","author":"Jiang","year":"2014","journal-title":"J. Pathol."},{"issue":"26","key":"10.1016\/j.redox.2020.101616_bib71","doi-asserted-by":"crossref","first-page":"18494","DOI":"10.18632\/oncotarget.24892","article-title":"Connective tissue growth factor-specific monoclonal antibody inhibits growth of malignant mesothelioma in an orthotopic mouse model","volume":"9","author":"Ohara","year":"2018","journal-title":"Oncotarget"},{"issue":"7","key":"10.1016\/j.redox.2020.101616_bib72","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1038\/sj.onc.1210711","article-title":"A role for iron in Wnt signalling","volume":"27","author":"Brookes","year":"2008","journal-title":"Oncogene"},{"key":"10.1016\/j.redox.2020.101616_bib73","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2015.153","article-title":"Aspirin delays mesothelioma growth by inhibiting HMGB1-mediated tumor progression","volume":"6","author":"Yang","year":"2015","journal-title":"Cell Death Dis."}],"container-title":["Redox Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213231720308211?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213231720308211?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T15:17:54Z","timestamp":1784906274000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213231720308211"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":73,"alternative-id":["S2213231720308211"],"URL":"https:\/\/doi.org\/10.1016\/j.redox.2020.101616","relation":{},"ISSN":["2213-2317"],"issn-type":[{"value":"2213-2317","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Asbestos conceives Fe(II)-dependent mutagenic stromal milieu through ceaseless macrophage ferroptosis and \u03b2-catenin induction in mesothelium","name":"articletitle","label":"Article Title"},{"value":"Redox Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.redox.2020.101616","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"101616"}}