{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T06:22:25Z","timestamp":1793773345147,"version":"4.6.1"},"reference-count":89,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,2,12]],"date-time":"2021-02-12T00:00:00Z","timestamp":1613088000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21922702"],"award-info":[{"award-number":["21922702"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81770278"],"award-info":[{"award-number":["81770278"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81770422"],"award-info":[{"award-number":["81770422"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81921001"],"award-info":[{"award-number":["81921001"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81970424"],"award-info":[{"award-number":["81970424"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82070445"],"award-info":[{"award-number":["82070445"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002338","name":"Ministry of Education of the People's Republic of China","doi-asserted-by":"publisher","award":["Q2017004"],"award-info":[{"award-number":["Q2017004"]}],"id":[{"id":"10.13039\/501100002338","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004826","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["7171010"],"award-info":[{"award-number":["7171010"]}],"id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004826","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["7182168"],"award-info":[{"award-number":["7182168"]}],"id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004826","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["7191012"],"award-info":[{"award-number":["7191012"]}],"id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011259","name":"State Key Laboratory of Robotics","doi-asserted-by":"publisher","award":["SKLP-K201703"],"award-info":[{"award-number":["SKLP-K201703"]}],"id":[{"id":"10.13039\/501100011259","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011259","name":"State Key Laboratory of Robotics","doi-asserted-by":"publisher","award":["SKLP-K201804"],"award-info":[{"award-number":["SKLP-K201804"]}],"id":[{"id":"10.13039\/501100011259","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Redox Biology"],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1016\/j.redox.2021.101898","type":"journal-article","created":{"date-parts":[[2021,2,21]],"date-time":"2021-02-21T17:16:53Z","timestamp":1613927813000},"page":"101898","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":51,"special_numbering":"C","title":["Endogenous SO2-dependent Smad3 redox modification controls vascular remodeling"],"prefix":"10.1016","volume":"41","author":[{"given":"Yaqian","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zongmin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lulu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huan","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6925-1268","authenticated-orcid":false,"given":"Chu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selena Ying","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dingfang","family":"Bu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zaifeng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhigang","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piaoliu","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqi","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaoshu","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youngeun","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renan B.","family":"Ferreira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate S.","family":"Carroll","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junbao","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongfang","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.redox.2021.101898_bib1","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/S0195-668X(02)00808-4","article-title":"The association of daily sulfur dioxide air pollution levels with hospital admissions for cardiovascular diseases in Europe (the Aphea-ii study)","volume":"24","author":"Sunyer","year":"2003","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.redox.2021.101898_bib2","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1146\/annurev.nu.06.070186.001143","article-title":"Metabolism of sulfur-containing amino acids","volume":"6","author":"Stipanuk","year":"1986","journal-title":"Annu. Rev. Nutr."},{"key":"10.1016\/j.redox.2021.101898_bib3","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1097\/01.shk.0000183393.83272.de","article-title":"Oxidative stress-dependent conversion of hydrogen sulfide to sulfite by activated neutrophils","volume":"24","author":"Mitsuhashi","year":"2005","journal-title":"Shock"},{"key":"10.1016\/j.redox.2021.101898_bib4","doi-asserted-by":"crossref","first-page":"559","DOI":"10.3389\/fchem.2018.00559","article-title":"SO2 donors and prodrugs, and their possible applications: a review","volume":"6","author":"Wang","year":"2018","journal-title":"Front. Chem."},{"key":"10.1016\/j.redox.2021.101898_bib5","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1111\/j.1745-7254.2008.00845.x","article-title":"Endogenously generated sulfur dioxide and its vasorelaxant effect in rats","volume":"29","author":"Du","year":"2008","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.redox.2021.101898_bib6","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.bbrc.2011.10.012","article-title":"Endogenous generation of sulfur dioxide in rat tissues","volume":"415","author":"Luo","year":"2011","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.redox.2021.101898_bib7","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1093\/clinchem\/41.6.897","article-title":"Determination of total serum sulfite by HPLC with fluorescence detection","volume":"41","author":"Ji","year":"1995","journal-title":"Clin. Chem."},{"key":"10.1016\/j.redox.2021.101898_bib8","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/j.bbrc.2003.10.055","article-title":"Identification of carbonyl sulfide and sulfur dioxide in porcine coronary artery by gas chromatography\/mass spectrometry, possible relevance to EDHF","volume":"311","author":"Balazy","year":"2003","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.redox.2021.101898_bib9","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.3109\/08958370902798463","article-title":"Vasodilator effect of gaseous sulfur dioxide and regulation of its level by Ach in rat vascular tissues","volume":"21","author":"Meng","year":"2009","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.redox.2021.101898_bib10","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1111\/j.1440-1681.2011.05528.x","article-title":"Sulfur dioxide derivatives depress L-type calcium channel in rat cardiomyocytes","volume":"38","author":"Zhang","year":"2011","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.redox.2021.101898_bib11","doi-asserted-by":"crossref","first-page":"e1251","DOI":"10.1038\/cddis.2014.229","article-title":"Sulfur dioxide inhibits vascular smooth muscle cell proliferation via suppressing the Erk\/MAP kinase pathway mediated by cAMP\/PKA signaling","volume":"5","author":"Liu","year":"2014","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.redox.2021.101898_bib12","doi-asserted-by":"crossref","first-page":"R1073","DOI":"10.1152\/ajpregu.00101.2015","article-title":"The vasodilatory effect of sulfur dioxide via SGC\/cGMP\/PKG pathway in association with sulfhydryl-dependent dimerization","volume":"310","author":"Yao","year":"2016","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.redox.2021.101898_bib13","doi-asserted-by":"crossref","first-page":"27026","DOI":"10.1038\/srep27026","article-title":"Endogenous sulfur dioxide is a novel adipocyte-derived inflammatory inhibitor","volume":"6","author":"Zhang","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.redox.2021.101898_bib14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1089\/ars.2017.7058","article-title":"A review of hydrogen sulfide synthesis, metabolism, and measurement: is modulation of hydrogen sulfide a novel therapeutic for cancer?","volume":"31","author":"Cao","year":"2019","journal-title":"Antioxidants Redox Signal."},{"key":"10.1016\/j.redox.2021.101898_bib15","doi-asserted-by":"crossref","first-page":"101675","DOI":"10.1016\/j.redox.2020.101675","article-title":"Hydrogen sulfide and DNA repair","volume":"38","author":"Shackelford","year":"2021","journal-title":"Redox Biol"},{"key":"10.1016\/j.redox.2021.101898_bib16","doi-asserted-by":"crossref","first-page":"L403","DOI":"10.1152\/ajplung.00327.2014","article-title":"Working with nitric oxide and hydrogen sulfide in biological systems","volume":"308","author":"Yuan","year":"2015","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"key":"10.1016\/j.redox.2021.101898_bib17","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.atherosclerosis.2010.12.037","article-title":"Regulatory effects of sulfur dioxide on the development of atherosclerotic lesions and vascular hydrogen sulfide in atherosclerotic rats","volume":"215","author":"Li","year":"2011","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.redox.2021.101898_bib18","first-page":"1219","article-title":"Sulfur dioxide restores calcium homeostasis disturbance in rat with isoproterenol-induced myocardial injury","volume":"27","author":"Chen","year":"2012","journal-title":"Histol. Histopathol."},{"key":"10.1016\/j.redox.2021.101898_bib19","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1097\/TP.0b013e318195fe82","article-title":"Endogenous sulfur dioxide aggravates myocardial injury in isolated rat heart with ischemia and reperfusion","volume":"87","author":"Zhang","year":"2009","journal-title":"Transplantation"},{"key":"10.1016\/j.redox.2021.101898_bib20","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1038\/labinvest.2009.102","article-title":"Effects of sulfur dioxide on hypoxic pulmonary vascular structural remodeling","volume":"90","author":"Sun","year":"2010","journal-title":"Lab. Invest."},{"key":"10.1016\/j.redox.2021.101898_bib21","doi-asserted-by":"crossref","first-page":"8961951","DOI":"10.1155\/2016\/8961951","article-title":"Endogenous sulfur dioxide: a new member of gasotransmitter family in the cardiovascular system","volume":"2016","author":"Huang","year":"2016","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.redox.2021.101898_bib22","doi-asserted-by":"crossref","first-page":"19503","DOI":"10.1038\/srep19503","article-title":"Endogenous sulfur dioxide alleviates collagen remodeling via inhibiting TGF-\u03b2\/Smad pathway in vascular smooth muscle cells","volume":"6","author":"Huang","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.redox.2021.101898_bib23","doi-asserted-by":"crossref","first-page":"5588","DOI":"10.1021\/jacs.7b01791","article-title":"Diverse redoxome reactivity profiles of carbon nucleophiles","volume":"139","author":"Gupta","year":"2017","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.redox.2021.101898_bib24","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1007\/s11426-016-0411-7","article-title":"A novel coumarin-based water-soluble fluorescent probe for endogenously generated SO2 in living cells","volume":"60","author":"Yang","year":"2017","journal-title":"Sci. China (Chem.)"},{"key":"10.1016\/j.redox.2021.101898_bib25","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1161\/ATVBAHA.118.310713","article-title":"Protective role of mPGES-1 (microsomal prostaglandin E synthase-1)-derived PGE2 (prostaglandin E2) and the endothelial EP4 (prostaglandin E receptor) in vascular responses to injury","volume":"38","author":"Hao","year":"2018","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.redox.2021.101898_bib26","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1002\/1526-968X(200009)28:1<15::AID-GENE20>3.0.CO;2-C","article-title":"Temporally controlled somatic mutagenesis in smooth muscle","volume":"28","author":"K\u00fchbandner","year":"2000","journal-title":"Genesis"},{"key":"10.1016\/j.redox.2021.101898_bib27","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1008729","article-title":"Quantitative live imaging of Venus::BMAL1 in a mouse model reveals complex dynamics of the master circadian clock regulator","volume":"16","author":"Yang","year":"2020","journal-title":"PLoS Genet."},{"key":"10.1016\/j.redox.2021.101898_bib28","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1152\/physrev.00026.2014","article-title":"Transient receptor potential channels in the vasculature","volume":"95","author":"Earley","year":"2015","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.redox.2021.101898_bib29","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1161\/CIRCULATIONAHA.115.020754","article-title":"Genetic and pharmacologic inhibition of the chemokine receptor CXCR2 prevents experimental hypertension and vascular dysfunction","volume":"134","author":"Wang","year":"2016","journal-title":"Circulation"},{"key":"10.1016\/j.redox.2021.101898_bib30","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.ijcard.2016.09.111","article-title":"Downregulated endogenous sulfur dioxide\/aspartate aminotransferase pathway is involved in angiotensin II-stimulated cardiomyocyte autophagy and myocardial hypertrophy in mice","volume":"225","author":"Chen","year":"2016","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.redox.2021.101898_bib31","doi-asserted-by":"crossref","first-page":"H1096","DOI":"10.1152\/ajpheart.00241.2009","article-title":"TRPV4-dependent dilation of peripheral resistance arteries influences arterial pressure","volume":"297","author":"Earley","year":"2009","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.redox.2021.101898_bib32","doi-asserted-by":"crossref","first-page":"14287","DOI":"10.1038\/ncomms14287","article-title":"Cellular mechano-environment regulates the mammary circadian clock","volume":"8","author":"Yang","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.redox.2021.101898_bib33","doi-asserted-by":"crossref","first-page":"e76","DOI":"10.1002\/cpps.76","article-title":"Proteome-wide analysis of cysteine S-sulfenylation using a benzothiazine-based probe","volume":"95","author":"Fu","year":"2019","journal-title":"Curr. Protein Pept. Sci."},{"key":"10.1016\/j.redox.2021.101898_bib34","doi-asserted-by":"crossref","first-page":"D1211","DOI":"10.1093\/nar\/gky869","article-title":"iProX: an integrated proteome resource","volume":"47","author":"Ma","year":"2019","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.redox.2021.101898_bib35","doi-asserted-by":"crossref","first-page":"101316","DOI":"10.1016\/j.redox.2019.101316","article-title":"Cysteine oxidation triggers amyloid fibril formation of the tumor suppressor p16INK4A","volume":"28","author":"G\u00f6bl","year":"2020","journal-title":"Redox Biol"},{"key":"10.1016\/j.redox.2021.101898_bib36","doi-asserted-by":"crossref","first-page":"4755","DOI":"10.1074\/jbc.M112.413492","article-title":"RegB kinase activity is repressed by oxidative formation of cysteine sulfenic acid","volume":"288","author":"Wu","year":"2013","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.redox.2021.101898_bib37","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1161\/CIRCRESAHA.111.263525","article-title":"Redox-sensitive sulfenic acid modification regulates surface expression of the cardiovascular voltage-gated potassium channel Kv1.5","volume":"111","author":"Svoboda","year":"2012","journal-title":"Circ. Res."},{"key":"10.1016\/j.redox.2021.101898_bib38","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.redox.2018.01.012","article-title":"Renal protective effect of polysulfide in cisplatin-induced nephrotoxicity","volume":"15","author":"Cao","year":"2018","journal-title":"Redox Biol"},{"key":"10.1016\/j.redox.2021.101898_bib39","doi-asserted-by":"crossref","first-page":"9741","DOI":"10.1074\/jbc.M113.517995","article-title":"Hydrogen sulfide suppresses oxidized low-density lipoprotein (ox-LDL)-stimulated monocyte chemoattractant protein 1 generation from macrophages via the nuclear factor \u03bab (NF-\u03baB) pathway","volume":"289","author":"Du","year":"2014","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.redox.2021.101898_bib40","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1161\/01.HYP.25.5.1111","article-title":"A noninvasive computerized tail-cuff system for measuring blood pressure in mice","volume":"25","author":"Krege","year":"1995","journal-title":"Hypertension"},{"key":"10.1016\/j.redox.2021.101898_bib41","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S1056-8719(00)00126-X","article-title":"Direct and indirect methods used to study arterial blood pressure","volume":"44","author":"Van Vliet","year":"2000","journal-title":"J. Pharmacol. Toxicol. Methods"},{"key":"10.1016\/j.redox.2021.101898_bib42","doi-asserted-by":"crossref","first-page":"4707","DOI":"10.1021\/ie020275i","article-title":"Kinetics of reaction between hydrogen sulfide and sulfur dioxide in sulfuric acid solutions","volume":"41","author":"Wang","year":"2002","journal-title":"Ind. Eng. Chem. Res."},{"key":"10.1016\/j.redox.2021.101898_bib43","doi-asserted-by":"crossref","first-page":"11287","DOI":"10.1021\/ic1007389","article-title":"Kinetics and mechanism of peroxymonocarbonate formation","volume":"49","author":"Bakhmutova-Albert","year":"2010","journal-title":"Inorg. Chem."},{"key":"10.1016\/j.redox.2021.101898_bib44","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.freeradbiomed.2019.09.010","article-title":"Enhanced hyperoxidation of peroxiredoxin 2 and peroxiredoxin 3 in the presence of bicarbonate\/CO2","volume":"145","author":"Peskin","year":"2019","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.redox.2021.101898_bib45","doi-asserted-by":"crossref","first-page":"12330","DOI":"10.1074\/jbc.RA119.009001","article-title":"Bicarbonate is essential for protein-tyrosine phosphatase 1b (PTP1B) oxidation and cellular signaling through EGF-triggered phosphorylation cascades","volume":"294","author":"Dagnell","year":"2019","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.redox.2021.101898_bib46","doi-asserted-by":"crossref","first-page":"8385","DOI":"10.1021\/acs.jpca.9b05444","article-title":"Sulfuric acid formation via H2SO3 oxidation by H2O2 in the atmosphere","volume":"123","author":"Shostak","year":"2019","journal-title":"J. Phys. Chem."},{"key":"10.1016\/j.redox.2021.101898_bib47","doi-asserted-by":"crossref","first-page":"13768","DOI":"10.1021\/acs.est.5b01658","article-title":"Oxidation of gas-phase SO2 on the surfaces of acidic microdroplets: implications for sulfate and sulfate radical anion formation in the atmospheric liquid phase","volume":"49","author":"Hung","year":"2015","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.redox.2021.101898_bib48","doi-asserted-by":"crossref","first-page":"2096","DOI":"10.1021\/j100587a005","article-title":"Kinetics of the oxidation of sulfite by hydrogen peroxide in acidic solution","volume":"79","author":"Hoffmann","year":"1975","journal-title":"J. Phys. Chem."},{"key":"10.1016\/j.redox.2021.101898_bib49","doi-asserted-by":"crossref","DOI":"10.1074\/mcp.R111.013037","article-title":"Regulatory control or oxidative damage? Proteomic approaches to interrogate the role of cysteine oxidation status in biological processes","volume":"11","author":"Held","year":"2012","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1016\/j.redox.2021.101898_bib50","doi-asserted-by":"crossref","first-page":"4633","DOI":"10.1021\/cr300163e","article-title":"Cysteine-mediated redox signaling: chemistry, biology, and tools for discovery","volume":"113","author":"Paulsen","year":"2013","journal-title":"Chem. Rev."},{"key":"10.1016\/j.redox.2021.101898_bib51","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1089\/ars.2020.8074","article-title":"Reactive oxygen species induced p53 activation: DNA damage, redox signaling, or both?","volume":"33","author":"Shi","year":"2020","journal-title":"Antioxidants Redox Signal."},{"key":"10.1016\/j.redox.2021.101898_bib52","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1021\/acs.accounts.9b00562","article-title":"Activity-based sensing for site-specific proteomic analysis of cysteine oxidation","volume":"53","author":"Shi","year":"2020","journal-title":"Acc. Chem. Res."},{"key":"10.1016\/j.redox.2021.101898_bib53","doi-asserted-by":"crossref","first-page":"21256","DOI":"10.1073\/pnas.1906768116","article-title":"Mining for protein S-sulfenylation in Arabidopsis uncovers redox-sensitive sites","volume":"116","author":"Huang","year":"2019","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.redox.2021.101898_bib54","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.chom.2013.02.004","article-title":"Proteome-wide quantification and characterization of oxidation-sensitive cysteines in pathogenic bacteria","volume":"13","author":"Deng","year":"2013","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.redox.2021.101898_bib55","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.mrfmmm.2008.04.008","article-title":"Evolution of the redox function in mammalian apurinic\/apyrimidinic endonuclease","volume":"643","author":"Georgiadis","year":"2008","journal-title":"Mutat. Res."},{"key":"10.1016\/j.redox.2021.101898_bib56","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1038\/nprot.2008.211","article-title":"Systematic and integrative analysis of large gene lists using david bioinformatics resources","volume":"4","author":"Huang da","year":"2009","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.redox.2021.101898_bib57","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.ajhg.2018.08.001","article-title":"Genetic regulatory mechanisms of smooth muscle cells map to coronary artery disease risk loci","volume":"103","author":"Liu","year":"2018","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.redox.2021.101898_bib58","doi-asserted-by":"crossref","first-page":"4776","DOI":"10.1038\/ncomms5776","article-title":"Site-specific mapping and quantification of protein S-sulphenylation in cells","volume":"5","author":"Yang","year":"2014","journal-title":"Nat. Commun."},{"key":"10.1016\/j.redox.2021.101898_bib59","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1021\/cb900105q","article-title":"Mining the thiol proteome for sulfenic acid modifications reveals new targets for oxidation in cells","volume":"4","author":"Leonard","year":"2009","journal-title":"ACS Chem. Biol."},{"key":"10.1016\/j.redox.2021.101898_bib60","doi-asserted-by":"crossref","first-page":"20327","DOI":"10.1074\/jbc.C300134200","article-title":"Features of a Smad3 MH1-DNA complex. Roles of water and zinc in DNA binding","volume":"278","author":"Chai","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.redox.2021.101898_bib61","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.jmb.2003.10.065","article-title":"Redox-dependent changes in RsrA, an anti-sigma factor in Streptomyces coelicolor: zinc release and disulfide bond formation","volume":"335","author":"Bae","year":"2004","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.redox.2021.101898_bib62","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1161\/01.RES.0000218782.52610.dc","article-title":"Essential role of Smad3 in angiotensin II-induced vascular fibrosis","volume":"98","author":"Wang","year":"2006","journal-title":"Circ. Res."},{"key":"10.1016\/j.redox.2021.101898_bib63","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1007681","article-title":"Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk","volume":"14","author":"Iyer","year":"2018","journal-title":"PLoS Genet."},{"key":"10.1016\/j.redox.2021.101898_bib64","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1152\/physrev.00029.2006","article-title":"Nitric oxide and peroxynitrite in health and disease","volume":"87","author":"Pacher","year":"2007","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.redox.2021.101898_bib65","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1038\/nrcardio.2017.224","article-title":"Nitric oxide signalling in cardiovascular health and disease","volume":"15","author":"Farah","year":"2018","journal-title":"Nat. Rev. Cardiol."},{"key":"10.1016\/j.redox.2021.101898_bib66","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1038\/nrd2425","article-title":"Hydrogen sulphide and its therapeutic potential","volume":"6","author":"Szab\u00f3","year":"2007","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.redox.2021.101898_bib67","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1161\/CIRCRESAHA.118.311134","article-title":"Evolution of hydrogen sulfide therapeutics to treat cardiovascular disease","volume":"123","author":"Li","year":"2018","journal-title":"Circ. Res."},{"key":"10.1016\/j.redox.2021.101898_bib68","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.tibs.2015.08.007","article-title":"H2S: a novel gasotransmitter that signals by sulfhydration","volume":"40","author":"Paul","year":"2015","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.redox.2021.101898_bib69","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.redox.2016.08.004","article-title":"Hydrogen sulfide metabolism regulates endothelial solute barrier function","volume":"9","author":"Yuan","year":"2016","journal-title":"Redox Biol"},{"key":"10.1016\/j.redox.2021.101898_bib70","doi-asserted-by":"crossref","first-page":"5125","DOI":"10.1074\/jbc.271.9.5125","article-title":"In vivo and in vitro iron-replaced zinc finger generates free radicals and causes DNA damage","volume":"271","author":"Conte","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.redox.2021.101898_bib71","first-page":"646","article-title":"Metal replacement in DNA-binding zinc finger proteins and its relevance to mutagenicity and carcinogenicity through free radical generation","volume":"11","author":"Sarkar","year":"1995","journal-title":"Nutrition"},{"key":"10.1016\/j.redox.2021.101898_bib72","first-page":"99","article-title":"The pH paradox in ischemia-reperfusion injury to cardiac myocytes","volume":"76","author":"Lemasters","year":"1996","journal-title":"EXS."},{"key":"10.1016\/j.redox.2021.101898_bib73","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1089\/ars.2019.7777","article-title":"Direct proteomic mapping of cysteine persulfidation","volume":"33","author":"Fu","year":"2020","journal-title":"Antioxidants Redox Signal."},{"key":"10.1016\/j.redox.2021.101898_bib74","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1021\/acs.chemrev.7b00205","article-title":"Chemical biology of H2S signaling through persulfidation","volume":"118","author":"Filipovic","year":"2018","journal-title":"Chem. Rev."},{"key":"10.1016\/j.redox.2021.101898_bib75","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1038\/nrm3391","article-title":"H\u2082S signalling through protein sulfhydration and beyond","volume":"13","author":"Paul","year":"2012","journal-title":"Nat. Rev. Mol. Cell. Biol."},{"key":"10.1016\/j.redox.2021.101898_bib76","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1016\/j.cmet.2019.10.007","article-title":"Selective persulfide detection reveals evolutionarily conserved antiaging effects of S-sulfhydration","volume":"30","author":"Zivanovic","year":"2019","journal-title":"Cell Metabol."},{"key":"10.1016\/j.redox.2021.101898_bib77","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1039\/c29710000339","article-title":"The nature of the radical intermediates in the reactions between hydroperoxides and sulphur dioxide and their reaction with alkene derivatives: electron spin resonance study","author":"Flockhart","year":"1971","journal-title":"J. Chem. Soc. D Chem. Commun."},{"key":"10.1016\/j.redox.2021.101898_bib78","doi-asserted-by":"crossref","first-page":"5050","DOI":"10.1016\/S0021-9258(18)34633-7","article-title":"The formation of sulfur trioxide radical anion during the prostaglandin hydroperoxidase-catalyzed oxidation of bisulfite (hydrated sulfur dioxide)","volume":"257","author":"Mottley","year":"1982","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.redox.2021.101898_bib79","series-title":"Sulfite-induced lipid peroxidation","first-page":"189","volume":"16","author":"Lizada","year":"1981"},{"key":"10.1016\/j.redox.2021.101898_bib80","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.bbrc.2020.02.040","article-title":"Negative auto-regulation of sulfur dioxide generation in vascular endothelial cells: AAT1 S-sulfenylation","volume":"525","author":"Song","year":"2020","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.redox.2021.101898_bib81","doi-asserted-by":"crossref","first-page":"2655","DOI":"10.1042\/CS20170274","article-title":"Sulphur dioxide suppresses inflammatory response by sulphenylating NF-\u03baB p65 at Cys38 in a rat model of acute lung injury","volume":"131","author":"Chen","year":"2017","journal-title":"Clin. Sci. (Lond.)"},{"key":"10.1016\/j.redox.2021.101898_bib82","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.tcm.2006.04.005","article-title":"The role of Smad3-dependent TGF-beta signal in vascular response to injury","volume":"16","author":"Yokote","year":"2006","journal-title":"Trends Cardiovasc. Med."},{"key":"10.1016\/j.redox.2021.101898_bib83","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1111\/jcmm.13973","article-title":"Chalcone flavokawain A attenuates TGF-\u03b21-induced fibrotic pathology via inhibition of ROS\/Smad3 signaling pathways and induction of Nrf2\/ARE-mediated antioxidant genes in vascular smooth muscle cells","volume":"23","author":"Hseu","year":"2019","journal-title":"J. Cell Mol. Med."},{"key":"10.1016\/j.redox.2021.101898_bib84","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s12291-016-0564-y","article-title":"Transforming growth factor-\u03b21\/Smad3 signaling and redox status in experimentally induced nephrotoxicity: impact of carnosine","volume":"32","author":"Keshk","year":"2017","journal-title":"Indian J. Clin. Biochem."},{"key":"10.1016\/j.redox.2021.101898_bib85","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1038\/sj.onc.1209826","article-title":"Smad3 is acetylated by p300\/CBP to regulate its transactivation activity","volume":"26","author":"Inoue","year":"2007","journal-title":"Oncogene"},{"key":"10.1016\/j.redox.2021.101898_bib86","doi-asserted-by":"crossref","first-page":"4777","DOI":"10.1038\/emboj.2011.393","article-title":"Ablation of Smurf2 reveals an inhibition in TGF-\u03b2 signalling through multiple mono-ubiquitination of Smad3","volume":"30","author":"Tang","year":"2011","journal-title":"EMBO J."},{"key":"10.1016\/j.redox.2021.101898_bib87","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1038\/ncb1968","article-title":"Oxidant-induced apoptosis is mediated by oxidation of the actin-regulatory protein cofilin","volume":"11","author":"Klamt","year":"2009","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.redox.2021.101898_bib88","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.freeradbiomed.2015.05.011","article-title":"Nox4-dependent activation of cofilin mediates VSMC reorientation in response to cyclic stretching","volume":"85","author":"Montenegro","year":"2015","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.redox.2021.101898_bib89","first-page":"22","article-title":"Influence of sulfur dioxide and its derivatives on rats' blood pressure","volume":"23","author":"Du","year":"2008","journal-title":"J. Appl. Clin. Pediatr."}],"container-title":["Redox Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S221323172100046X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S221323172100046X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,6]],"date-time":"2024-05-06T23:40:19Z","timestamp":1715038819000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S221323172100046X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":89,"alternative-id":["S221323172100046X"],"URL":"https:\/\/doi.org\/10.1016\/j.redox.2021.101898","relation":{},"ISSN":["2213-2317"],"issn-type":[{"value":"2213-2317","type":"print"}],"subject":[],"published":{"date-parts":[[2021,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Endogenous SO2-dependent Smad3 redox modification controls vascular remodeling","name":"articletitle","label":"Article Title"},{"value":"Redox Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.redox.2021.101898","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"101898"}}