{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T11:55:11Z","timestamp":1791287711145,"version":"4.3.0"},"reference-count":86,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,6]],"date-time":"2022-05-06T00:00:00Z","timestamp":1651795200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100022077","name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","doi-asserted-by":"publisher","award":["MetaboHUB-ANR-11-INBS-0010"],"award-info":[{"award-number":["MetaboHUB-ANR-11-INBS-0010"]}],"id":[{"id":"10.13039\/501100022077","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Redox Biology"],"published-print":{"date-parts":[[2022,7]]},"DOI":"10.1016\/j.redox.2022.102333","type":"journal-article","created":{"date-parts":[[2022,5,12]],"date-time":"2022-05-12T01:58:49Z","timestamp":1652320729000},"page":"102333","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Maternal heme-enriched diet promotes a gut pro-oxidative status associated with microbiota alteration, gut leakiness and glucose intolerance in mice offspring"],"prefix":"10.1016","volume":"53","author":[{"given":"Ana\u00efs","family":"Mazenc","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lo\u00efc","family":"Mervant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Maslo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corinne","family":"Lencina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9rie","family":"B\u00e9zirard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathilde","family":"Lev\u00eaque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingrid","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9rie","family":"Alquier-Bacqui\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Naud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9cile","family":"H\u00e9li\u00e8s-Toussaint","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Debrauwer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvie","family":"Chevolleau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7oise","family":"Gu\u00e9raud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrice H.F.","family":"Pierre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vassilia","family":"Th\u00e9odorou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7214-1134","authenticated-orcid":false,"given":"Ma\u00efwenn","family":"Olier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.redox.2022.102333_bib1","doi-asserted-by":"crossref","first-page":"10","DOI":"10.25220\/WNJ.V05.S1.0002","article-title":"The role of iron adequacy for maternal and fetal health","volume":"5","author":"Sungkar","year":"2021","journal-title":"World Nutrition J."},{"key":"10.1016\/j.redox.2022.102333_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/nu9121327","article-title":"Iron supplementation during pregnancy and infancy: uncertainties and implications for research and policy","volume":"9","author":"Brannon","year":"2017","journal-title":"Nutrients"},{"key":"10.1016\/j.redox.2022.102333_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbamcr.2019.118535","article-title":"Iron homeostasis and oxidative stress: an intimate relationship","volume":"1866","author":"Galaris","year":"2019","journal-title":"Biochim. Biophys. Acta Mol. Cell Res."},{"key":"10.1016\/j.redox.2022.102333_bib4","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.mam.2005.07.001","article-title":"Iron, oxidative stress and human health","volume":"26","author":"Puntarulo","year":"2005","journal-title":"Mol. Aspect. Med."},{"key":"10.1016\/j.redox.2022.102333_bib5","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1038\/nchembio.1416","article-title":"The role of iron and reactive oxygen species in cell death","volume":"10","author":"Dixon","year":"2014","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.redox.2022.102333_bib6","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/8629024","article-title":"Dual role of ROS as signal and stress agents: iron tips the balance in favor of toxic effects","volume":"2016","author":"Gammella","year":"2016","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.redox.2022.102333_bib7","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1542\/peds.2008-1047","article-title":"Iron homeostasis in the neonate","volume":"123","author":"Collard","year":"2009","journal-title":"Pediatrics"},{"key":"10.1016\/j.redox.2022.102333_bib8","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.siny.2010.04.001","article-title":"Maturation of the antioxidant system and the effects on preterm birth","volume":"15","author":"Davis","year":"2010","journal-title":"Semin. Fetal Neonatal Med."},{"key":"10.1016\/j.redox.2022.102333_bib9","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/bs.afnr.2021.01.002","volume":"96","author":"Fairweather-Tait","year":"2021","journal-title":"Adv. Food Nutr. Res."},{"key":"10.1016\/j.redox.2022.102333_bib10","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.earlhumdev.2015.08.013","article-title":"Human breast milk: a review on its composition and bioactivity","volume":"91","author":"Andreas","year":"2015","journal-title":"Early Hum. Dev."},{"key":"10.1016\/j.redox.2022.102333_bib11","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.meatsci.2016.09.012","article-title":"Iron in red meat\u2013friend or foe","volume":"123","author":"Czerwonka","year":"2017","journal-title":"Meat Sci."},{"key":"10.1016\/j.redox.2022.102333_bib12","first-page":"177","volume":"4","author":"Bastide","year":"2011"},{"key":"10.1016\/j.redox.2022.102333_bib13","doi-asserted-by":"crossref","DOI":"10.1007\/s11892-018-1071-8","article-title":"Red meat consumption (heme iron intake) and risk for diabetes and comorbidities?","volume":"18","author":"Misra","year":"2018","journal-title":"Curr. Diabetes Rep."},{"key":"10.1016\/j.redox.2022.102333_bib14","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.fct.2019.05.023","article-title":"Estimation of the burden of disease attributable to red meat consumption in France: influence on colorectal cancer and cardiovascular diseases","volume":"130","author":"De Oliveira Mota","year":"2019","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.redox.2022.102333_bib15","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1158\/0008-5472.CAN-14-2554","article-title":"A central role for heme iron in colon carcinogenesis associated with red meat intake","volume":"75","author":"Bastide","year":"2015","journal-title":"Cancer Res."},{"key":"10.1016\/j.redox.2022.102333_bib16","doi-asserted-by":"crossref","first-page":"403","DOI":"10.3945\/an.113.003681","article-title":"Red meat, dietary heme iron, and risk of type 2 diabetes: the involvement of advanced lipoxidation endproducts","volume":"4","author":"White","year":"2013","journal-title":"Adv. Nutr."},{"key":"10.1016\/j.redox.2022.102333_bib17","first-page":"569","volume":"11","author":"Martin","year":"2018"},{"key":"10.1016\/j.redox.2022.102333_bib18","first-page":"1","article-title":"Heme iron intake, non-enzymatic antioxidant capacity, and risk of colorectal adenomas in a large cohort study of French women","volume":"24","author":"Bastide","year":"2016","journal-title":"Cancer Epidemiol. Biomarkers Prev."},{"key":"10.1016\/j.redox.2022.102333_bib19","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.3945\/ajcn.113.061069","article-title":"Calcium and \u03b1-tocopherol suppress cured-meat promotion of chemically induced colon carcinogenesis in rats and reduce associated biomarkers in human volunteers","volume":"98","author":"Pierre","year":"2013","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.redox.2022.102333_bib20","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1093\/aje\/kwx156","article-title":"Meat, dietary heme iron, and risk of type 2 diabetes mellitus","volume":"186","author":"Talaei","year":"2017","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.redox.2022.102333_bib21","article-title":"Body iron stores and heme-iron intake in relation to risk of type 2 diabetes: a systematic review and meta-analysis","volume":"7","author":"Zhao","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.redox.2022.102333_bib22","doi-asserted-by":"crossref","DOI":"10.1186\/1741-7015-10-119","article-title":"Dietary iron intake, body iron stores, and the risk of type 2 diabetes: a systematic review and meta-analysis","volume":"10","author":"Bao","year":"2012","journal-title":"BMC Med."},{"key":"10.1016\/j.redox.2022.102333_bib23","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1002\/jbt.10058","article-title":"Diabetes, oxidative stress, and antioxidants: a review","volume":"17","author":"Maritim","year":"2003","journal-title":"J. Biochem. Mol. Toxicol."},{"key":"10.1016\/j.redox.2022.102333_bib24","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1016\/S0891-5849(03)00185-0","article-title":"Biomarkers of diabetes-associated oxidative stress and antioxidant status in young diabetic patients with or without subclinical complications","volume":"34","author":"Mart\u00edn-Gall\u00e1n","year":"2003","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.redox.2022.102333_bib25","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1080\/109158199225440","article-title":"Effects of melatonin on oxidative stress in streptozotocin-induced diabetic rats","volume":"18","author":"Maritim","year":"1999","journal-title":"Int. J. Toxicol."},{"key":"10.1016\/j.redox.2022.102333_bib26","doi-asserted-by":"crossref","first-page":"101723","DOI":"10.1016\/j.redox.2020.101723","article-title":"Elevated 4-hydroxynonenal induces hyperglycaemia via Aldh3a1 loss in zebrafish and associates with diabetes progression in humans","volume":"37","author":"Lou","year":"2020","journal-title":"Redox Biol."},{"key":"10.1016\/j.redox.2022.102333_bib27","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.2337\/dc11-0135","article-title":"Gestational diabetes mellitus in relation to maternal dietary heme iron and nonheme iron intake","volume":"34","author":"Qiu","year":"2011","journal-title":"Diabetes Care"},{"key":"10.1016\/j.redox.2022.102333_bib28","doi-asserted-by":"crossref","first-page":"52","DOI":"10.7762\/cnr.2020.9.1.52","article-title":"The association between maternal dietary iron intake during the first trimester of pregnancy with pregnancy outcomes and pregnancy-related complications","volume":"9","author":"Hajianfar","year":"2020","journal-title":"Clinical Nutrition Res."},{"key":"10.1016\/j.redox.2022.102333_bib29","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1080\/14767058.2017.1406915","article-title":"Maternal and neonatal outcomes related to iron supplementation or iron status: a summary of meta-analyses","volume":"32","author":"Iqbal","year":"2017","journal-title":"J. Matern. Fetal Neonatal Med."},{"key":"10.1016\/j.redox.2022.102333_bib30","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1007\/s00394-017-1377-3","article-title":"Association between pre-pregnancy consumption of meat, iron intake, and the risk of gestational diabetes: the SUN project","volume":"57","author":"Mar\u00ed-Sanchis","year":"2018","journal-title":"Eur. J. Nutr."},{"key":"10.1016\/j.redox.2022.102333_bib31","article-title":"Gestational diabetes: higher animal protein intake during pregnancy is associated with increased risk, and higher vegetable protein intake with decreased risk","volume":"17","author":"Middleton","year":"2014","journal-title":"Evid. Base Nurs."},{"key":"10.1016\/j.redox.2022.102333_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/srep20683","article-title":"Diet-induced changes in maternal gut microbiota and metabolomic profiles influence programming of offspring obesity risk in rats","volume":"6","author":"Paul","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.redox.2022.102333_bib33","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1111\/apha.12130","article-title":"A maternal diet of fatty fish reduces body fat of offspring compared with a maternal diet of beef and a post-weaning diet of fish improves insulin sensitivity and lipid profile in adult C57BL\/6 male mice","volume":"209","author":"Hussain","year":"2013","journal-title":"Acta Physiol."},{"key":"10.1016\/j.redox.2022.102333_bib34","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1038\/ismej.2015.90","article-title":"Neonatal environment exerts a sustained influence on the development of the intestinal microbiota and metabolic phenotype","volume":"10","author":"Merrifield","year":"2016","journal-title":"ISME J."},{"key":"10.1016\/j.redox.2022.102333_bib35","doi-asserted-by":"crossref","DOI":"10.3390\/nu8010046","article-title":"Impact of diet composition in adult offspring is dependent on maternal diet during pregnancy and lactation in rats","volume":"8","author":"Hallam","year":"2016","journal-title":"Nutrients"},{"key":"10.1016\/j.redox.2022.102333_bib36","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1017\/S2040174417000733","article-title":"Epigenetics and DOHaD: from basics to birth and beyond","volume":"8","author":"Bianco-Miotto","year":"2017","journal-title":"J. Develop. Origins Health Dis."},{"key":"10.1016\/j.redox.2022.102333_bib37","first-page":"141","article-title":"The role of the microbiome in the developmental origins of health and disease","author":"Stiemsma","year":"2018","journal-title":"Pediatrics"},{"key":"10.1016\/j.redox.2022.102333_bib38","first-page":"212","article-title":"Diet-induced extinctions in the gut microbiota compound over generations","volume":"529","author":"Sonnenburg","year":"2016","journal-title":"Nature. Nature Publishing Group"},{"key":"10.1016\/j.redox.2022.102333_bib39","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1038\/nri.2017.77","article-title":"The theory of disappearing microbiota and the epidemics of chronic diseases","volume":"17","author":"Blaser","year":"2017","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.redox.2022.102333_bib40","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1080\/19490976.2015.1078051","article-title":"Rate of establishing the gut microbiota in infancy has consequences for future health","volume":"6","author":"Dogra","year":"2015","journal-title":"Gut Microb."},{"key":"10.1016\/j.redox.2022.102333_bib41","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1186\/s40168-019-0685-7","article-title":"Haem iron reshapes colonic luminal environment: impact on mucosal homeostasis and microbiome through aldehyde formation","volume":"7","author":"Martin","year":"2019","journal-title":"Microbiome"},{"key":"10.1016\/j.redox.2022.102333_bib42","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1111\/nmo.12820","article-title":"Malnutrition increases NO production and induces changes in inflammatory and oxidative status in the distal colon of lactating rats","volume":"28","author":"dos Santos-Junior","year":"2016","journal-title":"Neuro Gastroenterol. Motil."},{"key":"10.1016\/j.redox.2022.102333_bib43","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.3390\/antiox10081261","article-title":"Towards aldehydomics: untargeted trapping and analysis of reactive diet-related carbonyl compounds formed in the intestinal lumen","volume":"10","author":"Chevolleau","year":"2021","journal-title":"Antioxidants"},{"key":"10.1016\/j.redox.2022.102333_bib44","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1093\/bioinformatics\/btx791","article-title":"FROGS: find, rapidly, OTUs with Galaxy solution","volume":"34","author":"Escudi\u00e9","year":"2018","journal-title":"Bioinformatics"},{"key":"10.1016\/j.redox.2022.102333_bib45","doi-asserted-by":"crossref","first-page":"e593","DOI":"10.7717\/peerj.593","article-title":"Swarm: robust and fast clustering method for amplicon-based studies","volume":"2","author":"Mah\u00e9","year":"2014","journal-title":"PeerJ"},{"key":"10.1016\/j.redox.2022.102333_bib46","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1093\/carcin\/bgg130","article-title":"Meat and cancer: haemoglobin and haemin in a low-calcium diet promote colorectal carcinogenesis at the aberrant crypt stage in rats","volume":"24","author":"Pierre","year":"2003","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.redox.2022.102333_bib47","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0003-2697(79)90738-3","article-title":"Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction","volume":"95","author":"Ohkawa","year":"1979","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.redox.2022.102333_bib48","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.freeradbiomed.2005.08.011","article-title":"Enzyme immunoassay for a urinary metabolite of 4-hydroxynonenal as a marker of lipid peroxidation","volume":"40","author":"Gueraud","year":"2006","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.redox.2022.102333_bib49","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.bbi.2018.05.024","article-title":"Early life stress in mice is a suitable model for Irritable Bowel Syndrome but do not predispose to colitis nor increase susceptibility to enteric infections","volume":"73","author":"Riba","year":"2018","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.redox.2022.102333_bib50","doi-asserted-by":"crossref","first-page":"3055","DOI":"10.1093\/bioinformatics\/bty1054","article-title":"Diablo - an integrative, multiomics, multivariate method for multigroup classification","volume":"35","author":"Singh","year":"2019","journal-title":"Bioinformatics"},{"key":"10.1016\/j.redox.2022.102333_bib51","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1005752","article-title":"mixOmics: an R package for \u2019omics feature selection and multiple data integration","volume":"13","author":"Rohart","year":"2017","journal-title":"PLoS Comput. Biol."},{"key":"10.1016\/j.redox.2022.102333_bib52","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0160169","article-title":"MixMC: a multivariate statistical framework to gain insight into microbial communities","volume":"11","author":"L\u00ea Cao","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.redox.2022.102333_bib53","doi-asserted-by":"crossref","first-page":"2824","DOI":"10.1007\/s00125-006-0465-3","article-title":"Increased intestinal permeability precedes clinical onset of type 1 diabetes","volume":"49","author":"Bosi","year":"2006","journal-title":"Diabetologia"},{"key":"10.1016\/j.redox.2022.102333_bib54","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1080\/01635581.2015.976317","article-title":"Antibiotic suppression of intestinal microbiota reduces heme-induced lipoperoxidation associated with colon carcinogenesis in rats","volume":"67","author":"Martin","year":"2015","journal-title":"Nutr. Cancer"},{"key":"10.1016\/j.redox.2022.102333_bib55","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0049868","article-title":"Dietary heme alters microbiota and mucosa of mouse colon without functional changes in host-microbe cross-talk","volume":"7","author":"\u0132ssennagger","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.redox.2022.102333_bib56","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.tiv.2012.08.005","article-title":"Stobadine attenuates impairment of an intestinal barrier model caused by 4-hydroxynonenal","volume":"27","author":"Cindric","year":"2013","journal-title":"Toxicol. Vitro"},{"key":"10.1016\/j.redox.2022.102333_bib57","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1093\/carcin\/bgt084","article-title":"Dietary heme induces acute oxidative stress, but delayed cytotoxicity and compensatory hyperproliferation in mouse colon","volume":"34","author":"Ijssennagger","year":"2013","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.redox.2022.102333_bib58","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.1507645112","article-title":"Gut microbiota facilitates dietary heme-induced epithelial hyperproliferation by opening the mucus barrier in colon","volume":"112","author":"Ijssennagger","year":"2015","journal-title":"Proc. Natl. Acad. Sci. Unit. States Am."},{"key":"10.1016\/j.redox.2022.102333_bib59","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1093\/carcin\/bgl127","article-title":"Apc mutation induces resistance of colonic cells to lipoperoxide-triggered apoptosis induced by faecal water from haem-fed rats","volume":"28","author":"Pierre","year":"2007","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.redox.2022.102333_bib60","doi-asserted-by":"crossref","DOI":"10.3390\/metabo12020129","article-title":"Iron metabolism in normal and pathological pregnancies and fetal consequences","volume":"12","author":"M\u00e9gier","year":"2022","journal-title":"Metabolites"},{"key":"10.1016\/j.redox.2022.102333_bib61","doi-asserted-by":"crossref","first-page":"S43","DOI":"10.1111\/j.1753-4887.2011.00432.x","article-title":"Long-term brain and behavioral consequences of early iron deficiency","volume":"69","author":"Georgieff","year":"2011","journal-title":"Nutr. Rev."},{"key":"10.1016\/j.redox.2022.102333_bib62","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1001\/jamapsychiatry.2019.2309","article-title":"Association of prenatal maternal anemia with neurodevelopmental disorders","volume":"76","author":"Wiegersma","year":"2019","journal-title":"JAMA Psychiatr."},{"key":"10.1016\/j.redox.2022.102333_bib63","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1053\/meta.2001.22516","article-title":"Effects of maternal iron restriction in the rat on blood pressure, glucose tolerance, and serum lipids in the 3-month-old offspring","volume":"50","author":"Lewis","year":"2001","journal-title":"Metab., Clin. Exp."},{"key":"10.1016\/j.redox.2022.102333_bib64","doi-asserted-by":"crossref","first-page":"2555","DOI":"10.2337\/db08-0331","article-title":"The \u201cperfect storm\u201d for type 1 diabetes: the complex interplay between intestinal microbiota, gut permeability, and mucosal immunity","author":"Vaarala","year":"2008","journal-title":"Diabetes"},{"key":"10.1016\/j.redox.2022.102333_bib65","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/s00592-020-01563-z","article-title":"The crucial role of early-life gut microbiota in the development of type 1 diabetes","volume":"58","author":"Zhou","year":"2021","journal-title":"Acta Diabetol."},{"key":"10.1016\/j.redox.2022.102333_bib66","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0021184","article-title":"Lipid-induced peroxidation in the intestine is involved in glucose homeostasis imbalance in mice","volume":"6","author":"Serino","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.redox.2022.102333_bib67","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/nu11040894","article-title":"The good, the bad and the ugly of pregnancy nutrients and developmental programming of adult disease","volume":"11","author":"Hsu","year":"2019","journal-title":"Nutrients"},{"key":"10.1016\/j.redox.2022.102333_bib68","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1089\/ars.2011.4372","article-title":"In utero oxidative stress epigenetically programs antioxidant defense capacity and adulthood diseases","volume":"17","author":"Strakovsky","year":"2012","journal-title":"Antioxidants Redox Signal."},{"key":"10.1016\/j.redox.2022.102333_bib69","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fcimb.2021.671347","article-title":"Maternal obesity increases oxidative stress in placenta and it is associated with intestinal microbiota","volume":"11","author":"Hu","year":"2021","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.redox.2022.102333_bib70","doi-asserted-by":"crossref","DOI":"10.3390\/antiox7040049","article-title":"Sex-specificity of oxidative stress in newborns leading to a personalized antioxidant nutritive strategy","volume":"7","author":"Lavoie","year":"2018","journal-title":"Antioxidants"},{"key":"10.1016\/j.redox.2022.102333_bib71","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1476-9255-7-7","article-title":"Dextran sulfate sodium and 2,4,6-trinitrobenzene sulfonic acid induce lipid peroxidation by the proliferation of intestinal gram-negative bacteria in mice","volume":"7","author":"Lee","year":"2010","journal-title":"J. Inflamm."},{"key":"10.1016\/j.redox.2022.102333_bib72","doi-asserted-by":"crossref","DOI":"10.1016\/j.xcrm.2021.100393","article-title":"Infant gut strain persistence is associated with maternal origin, phylogeny, and traits including surface adhesion and iron acquisition","volume":"2","author":"Lou","year":"2021","journal-title":"Cell Reports Medicine"},{"key":"10.1016\/j.redox.2022.102333_bib73","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1111\/mmi.12438","article-title":"An anaerobic bacterium, Bacteroides thetaiotaomicron, uses a consortium of enzymes to scavenge hydrogen peroxide","volume":"90","author":"Mishra","year":"2013","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.redox.2022.102333_bib74","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/s40168-016-0181-2","article-title":"Genomic characterization of the uncultured Bacteroidales family S24-7 inhabiting the guts of homeothermic animals","volume":"4","author":"Ormerod","year":"2016","journal-title":"Microbiome"},{"key":"10.1016\/j.redox.2022.102333_bib75","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.chom.2015.01.001","article-title":"The dynamics of the human infant gut microbiome in development and in progression toward type 1 diabetes","volume":"17","author":"Kostic","year":"2015","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.redox.2022.102333_bib76","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.ebiom.2019.06.031","article-title":"Microbiome and type 1 diabetes","volume":"46","author":"Siljander","year":"2019","journal-title":"EBioMedicine. The Authors"},{"key":"10.1016\/j.redox.2022.102333_bib77","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0025792","article-title":"Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetes","volume":"6","author":"Brown","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.redox.2022.102333_bib78","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fmicb.2014.00678","article-title":"Bacteroides dorei dominates gut microbiome prior to autoimmunity in Finnish children at high risk for type 1 diabetes","volume":"5","author":"Davis-Richardson","year":"2014","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.redox.2022.102333_bib79","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1007\/s00125-014-3274-0","article-title":"Aberrant gut microbiota composition at the onset of type 1 diabetes in young children","volume":"57","author":"De Goffau","year":"2014","journal-title":"Diabetologia"},{"key":"10.1016\/j.redox.2022.102333_bib80","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1016\/j.cell.2016.04.007","article-title":"Variation in microbiome LPS immunogenicity contributes to autoimmunity in humans","volume":"165","author":"Vatanen","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.redox.2022.102333_bib81","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/6047145","article-title":"Enterotype Bacteroides is associated with a high risk in patients with diabetes: a pilot study","volume":"2020","author":"Wang","year":"2020","journal-title":"J. Diabetes Res."},{"key":"10.1016\/j.redox.2022.102333_bib82","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/nature11450","article-title":"A metagenome-wide association study of gut microbiota in type 2 diabetes","volume":"490","author":"Qin","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.redox.2022.102333_bib83","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1264\/jsme2.ME14054","article-title":"Intestinal colonization by a Lachnospiraceae bacterium contributes to the development of diabetes in obese mice","volume":"29","author":"Kameyama","year":"2014","journal-title":"Microb. Environ."},{"key":"10.1016\/j.redox.2022.102333_bib84","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1089\/ars.2005.7.256","article-title":"Lipid peroxidation in diabetes mellitus","volume":"7","author":"Dav\u00ec","year":"2005","journal-title":"Antioxidants Redox Signal."},{"key":"10.1016\/j.redox.2022.102333_bib85","doi-asserted-by":"crossref","first-page":"3199","DOI":"10.1161\/01.CIR.0000074205.17807.D0","article-title":"Enhanced lipid peroxidation and platelet activation in the early phase of type 1 diabetes mellitus: role of interleukin-6 and disease duration","volume":"107","author":"Dav\u00ec","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.redox.2022.102333_bib86","doi-asserted-by":"crossref","first-page":"15140","DOI":"10.1073\/pnas.1814558116","article-title":"Loss of gut barrier integrity triggers activation of islet-reactive T cells and autoimmune diabetes","volume":"116","author":"Sorini","year":"2019","journal-title":"Proc. Natl. Acad. Sci. U. S. A"}],"container-title":["Redox Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213231722001057?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213231722001057?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T06:27:30Z","timestamp":1761978450000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213231722001057"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":86,"alternative-id":["S2213231722001057"],"URL":"https:\/\/doi.org\/10.1016\/j.redox.2022.102333","relation":{},"ISSN":["2213-2317"],"issn-type":[{"value":"2213-2317","type":"print"}],"subject":[],"published":{"date-parts":[[2022,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Maternal heme-enriched diet promotes a gut pro-oxidative status associated with microbiota alteration, gut leakiness and glucose intolerance in mice offspring","name":"articletitle","label":"Article Title"},{"value":"Redox Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.redox.2022.102333","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"102333"}}