{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T04:40:40Z","timestamp":1768711240254,"version":"3.49.0"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,12,23]],"date-time":"2022-12-23T00:00:00Z","timestamp":1671753600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2018YFE0200502"],"award-info":[{"award-number":["2018YFE0200502"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21871210"],"award-info":[{"award-number":["21871210"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31971174"],"award-info":[{"award-number":["31971174"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81973269"],"award-info":[{"award-number":["81973269"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82070545"],"award-info":[{"award-number":["82070545"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Redox Biology"],"published-print":{"date-parts":[[2023,2]]},"DOI":"10.1016\/j.redox.2022.102590","type":"journal-article","created":{"date-parts":[[2022,12,29]],"date-time":"2022-12-29T12:06:40Z","timestamp":1672315600000},"page":"102590","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Targeted delivery of Nitric Oxide triggered by \u03b1-Glucosidase to Ameliorate NSAIDs-induced Enteropathy"],"prefix":"10.1016","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8235-1116","authenticated-orcid":false,"given":"Xianglu","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiarui","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhixin","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuguang","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guifang","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bangmao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hailong","family":"Cao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yangping","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2001-5878","authenticated-orcid":false,"given":"Jingli","family":"Hou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.redox.2022.102590_bib1","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/S0140-6736(87)91075-0","article-title":"Blood and protein loss via small-intestinal inflammation induced by non-steroidal anti-inflammatory drugs","volume":"2","author":"Bjarnason","year":"1987","journal-title":"Lancet"},{"issue":"10","key":"10.1016\/j.redox.2022.102590_bib2","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1136\/gut.2010.229906","article-title":"Non-steroidal anti-inflammatory drugs and risk of lower gastrointestinal adverse events: a nationwide study in Taiwan","volume":"60","author":"Chang","year":"2011","journal-title":"Gut"},{"issue":"5","key":"10.1016\/j.redox.2022.102590_bib3","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1007\/s00535-019-01657-8","article-title":"Current knowledge on non-steroidal anti-inflammatory drug-induced small-bowel damage: a comprehensive review","volume":"55","author":"Watanabe","year":"2020","journal-title":"J. Gastroenterol."},{"key":"10.1016\/j.redox.2022.102590_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1177\/17562848211038772","article-title":"Mucoprotective drugs can prevent and treat nonsteroidal anti-inflammatory drug-induced small bowel enteropathy: a systematic review and meta-analysis of randomized controlled trials","volume":"14","author":"Teutsch","year":"2021","journal-title":"Therap. Adv. Gastroenterol."},{"key":"10.1016\/j.redox.2022.102590_bib5","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2021.657457","article-title":"Gaseous mediators as a key molecular targets for the development of gastrointestinal-safe anti-inflammatory pharmacology","volume":"12","author":"Danielak","year":"2021","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.redox.2022.102590_bib6","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1111\/bph.13005","article-title":"Pharmacology of the \u2018gasotransmitters\u2019 NO, CO and H2S: translational opportunities","volume":"172","author":"Papapetropoulos","year":"2015","journal-title":"Br. J. Pharmacol."},{"issue":"3","key":"10.1016\/j.redox.2022.102590_bib7","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/S0016-5085(99)70448-8","article-title":"Enhanced anti-inflammatory effects of a nitric oxide-releasing derivative of mesalamine in rats","volume":"117","author":"Wallace","year":"1999","journal-title":"Gastroenterology"},{"issue":"2","key":"10.1016\/j.redox.2022.102590_bib8","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1111\/bph.14527","article-title":"Nitric oxide in the gastrointestinal tract: opportunities for drug development","volume":"176","author":"Wallace","year":"2019","journal-title":"Br. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.redox.2022.102590_bib9","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1006\/abbi.1999.1386","article-title":"Nitric oxide inhibits iron-induced lipid peroxidation in HL-60 cells","volume":"370","author":"Kelley","year":"1999","journal-title":"Arch. Biochem. Biophys."},{"issue":"3\u20134","key":"10.1016\/j.redox.2022.102590_bib10","first-page":"671","volume":"383","author":"Schafer","year":"2002","journal-title":"Comparing beta-carotene, vitamin E and nitric oxide as membrane antioxidants"},{"key":"10.1016\/j.redox.2022.102590_bib11","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1073\/pnas.98.1.355","article-title":"The biological lifetime of nitric oxide: implications for the perivascular dynamics of NO and O2","volume":"98","author":"Thomas","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"key":"10.1016\/j.redox.2022.102590_bib12","doi-asserted-by":"crossref","first-page":"e1907635","DOI":"10.1002\/smll.201907635","article-title":"Enzyme mimics for the catalytic generation of nitric oxide from endogenous prodrugs","volume":"16","author":"Yang","year":"2020","journal-title":"Small"},{"key":"10.1016\/j.redox.2022.102590_bib13","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1039\/D0NR07484E","article-title":"Advanced nitric oxide donors: chemical structure of NO drugs, NO nanomedicines and biomedical applications","volume":"13","author":"Yang","year":"2021","journal-title":"Nanoscale"},{"key":"10.1016\/j.redox.2022.102590_bib14","doi-asserted-by":"crossref","first-page":"e2101701","DOI":"10.1002\/adma.202101701","article-title":"Sphingosine 1-phosphate liposomes for targeted nitric oxide delivery to mediate anticancer effects against brain glioma tumors","volume":"33","author":"Liu","year":"2021","journal-title":"Adv. Mater."},{"key":"10.1016\/j.redox.2022.102590_bib15","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1038\/s41565-020-0701-x","article-title":"In situ electrochemical generation of nitric oxide for neuronal modulation","volume":"15","author":"Park","year":"2020","journal-title":"Nat. Nanotechnol."},{"key":"10.1016\/j.redox.2022.102590_bib16","doi-asserted-by":"crossref","DOI":"10.1002\/adma.201604932","article-title":"Localized and controlled delivery of nitric oxide to the conventional outflow pathway via enzyme biocatalysis: toward therapy for glaucoma","volume":"29","author":"Chandrawati","year":"2017","journal-title":"Adv. Mater."},{"key":"10.1016\/j.redox.2022.102590_bib17","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1038\/s41589-018-0190-5","article-title":"Targeted delivery of nitric oxide via a \u2018bump-and-hole\u2019-based enzyme\u2013prodrug pair","volume":"15","author":"Hou","year":"2018","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.redox.2022.102590_bib18","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.jconrel.2015.05.283","article-title":"Enzyme-functionalized vascular grafts catalyze in-situ release of nitric oxide from exogenous NO prodrug","volume":"210","author":"Wang","year":"2015","journal-title":"J. Contr. Release"},{"key":"10.1016\/j.redox.2022.102590_bib19","doi-asserted-by":"crossref","first-page":"3409","DOI":"10.1021\/ol701419a","article-title":"A prodrug of the nitric oxide donor","volume":"9","author":"Chakrapani","year":"2007","journal-title":"PROLI\/NO, Org. Lett."},{"key":"10.1016\/j.redox.2022.102590_bib20","doi-asserted-by":"crossref","first-page":"2625","DOI":"10.1016\/S0040-4039(01)00263-5","article-title":"Synthesis of peptide-diazeniumdiolate conjugates: towards enzyme activated antitumor agents","volume":"42","author":"Tang","year":"2001","journal-title":"Tetrahedron Lett."},{"key":"10.1016\/j.redox.2022.102590_bib21","doi-asserted-by":"crossref","first-page":"5321","DOI":"10.1021\/jm400146r","article-title":"Development and characterization of glutamyl-protected N-hydroxyguanidines as reno-active nitric oxide donor drugs with therapeutic potential in acute renal failure","volume":"56","author":"Zhang","year":"2013","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.redox.2022.102590_bib22","doi-asserted-by":"crossref","first-page":"8450","DOI":"10.1016\/j.biomaterials.2013.07.045","article-title":"Polysaccharide-based biomaterials with on-demand nitric oxide releasing property regulated by enzyme catalysis","volume":"34","author":"Zhao","year":"2013","journal-title":"Biomaterials"},{"key":"10.1016\/j.redox.2022.102590_bib23","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1021\/ol902481s","article-title":"Glycosylated PROLI\/NO derivatives as nitric oxide prodrugs","volume":"12","author":"Nandurdikar","year":"2010","journal-title":"Org. Lett."},{"key":"10.1016\/j.redox.2022.102590_bib24","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/BF00508014","article-title":"A quantitative histochemical technique for the characterisation of alpha-glucosidases in the brush-border membrane of rat jejunum","volume":"63","author":"Gutschmidt","year":"1979","journal-title":"Histochemistry"},{"key":"10.1016\/j.redox.2022.102590_bib25","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.jconrel.2004.10.012","article-title":"Influence of molecular weight on oral absorption of water soluble chitosans","volume":"102","author":"Chae","year":"2005","journal-title":"J. Contr. Release"},{"key":"10.1016\/j.redox.2022.102590_bib26","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1021\/acsbiomaterials.7b00262","article-title":"Succinylated chitosan derivative has local protective effects on intestinal inflammation","volume":"3","author":"Hyun","year":"2017","journal-title":"ACS Biomater. Sci. Eng."},{"key":"10.1016\/j.redox.2022.102590_bib27","doi-asserted-by":"crossref","first-page":"2856","DOI":"10.1021\/mp300162j","article-title":"Insight on the formation of chitosan nanoparticles through ionotropic gelation with tripolyphosphate","volume":"9","author":"Koukaras","year":"2012","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.redox.2022.102590_bib28","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/0378-5173(89)90229-9","article-title":"A novel in situ method to test polymers and coated microparticles for bioadhesion","volume":"52","author":"Rao","year":"1989","journal-title":"Int. J. Pharm. (Amst.)"},{"key":"10.1016\/j.redox.2022.102590_bib29","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0304-4165(97)00032-9","article-title":"Complexes of Fe2+ with diethyldithiocarbamate or N-methyl-D-glucamine dithiocarbamate as traps of nitric oxide in animal tissues: comparative investigations","volume":"1336","author":"Mikoyan","year":"1997","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.redox.2022.102590_bib30","doi-asserted-by":"crossref","first-page":"3684","DOI":"10.1021\/ja042967z","article-title":"Highly sensitive near-infrared fluorescent probes for nitric oxide and their application to isolated organs","volume":"127","author":"Sasaki","year":"2005","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.redox.2022.102590_bib31","doi-asserted-by":"crossref","first-page":"2608","DOI":"10.3389\/fimmu.2018.02608","article-title":"Maternal high fat diet alters gut microbiota of offspring and exacerbates DSS-induced colitis in adulthood","volume":"9","author":"Xie","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.redox.2022.102590_bib32","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.ajpath.2012.03.039","article-title":"High mobility group box 1 promotes small intestinal damage induced by nonsteroidal anti-inflammatory drugs through Toll-like receptor 4","volume":"181","author":"Nadatani","year":"2012","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.redox.2022.102590_bib33","doi-asserted-by":"crossref","DOI":"10.1038\/srep26129","article-title":"Paneth cell in adenomas of the distal colorectum is inversely associated with synchronous advanced adenoma and carcinoma","volume":"6","author":"Mahon","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.redox.2022.102590_bib34","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1038\/nature07416","article-title":"A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells","volume":"456","author":"Cadwell","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.redox.2022.102590_bib35","doi-asserted-by":"crossref","first-page":"13291","DOI":"10.1021\/ja981041m","article-title":"Exploring the mechanism of neighboring group assisted glycosylation reactions","volume":"120","author":"Nukada","year":"1998","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.redox.2022.102590_bib36","doi-asserted-by":"crossref","first-page":"5473","DOI":"10.1021\/ja002899q","article-title":"Chemistry of the diazeniumdiolates. 2. Kinetics and mechanism of dissociation to nitric oxide in aqueous solution","volume":"123","author":"Davies","year":"2001","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.redox.2022.102590_bib37","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/cmr.a.10080","article-title":"NMR spectroscopy in the study of carbohydrates: characterizing the structural complexity","volume":"19A","author":"Bubb","year":"2003","journal-title":"Concepts Magn. Reson."},{"key":"10.1016\/j.redox.2022.102590_bib38","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.jconrel.2004.10.012","article-title":"Influence of molecular weight on oral absorption of water soluble chitosans","volume":"102","author":"Chae","year":"2005","journal-title":"J. Contr. Release"},{"key":"10.1016\/j.redox.2022.102590_bib39","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/0378-5173(89)90229-9","article-title":"A novel in situ method to test polymers and coated microparticles for bioadhesion","volume":"52","author":"R Rao","year":"1989","journal-title":"Int. J. Pharm. (Amst.)"},{"key":"10.1016\/j.redox.2022.102590_bib40","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/S0076-6879(96)68015-X","article-title":"Quantitation of nitrate, nitrite, and nitrosating agents","volume":"268","author":"Wishnok","year":"1996","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.redox.2022.102590_bib41","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/0076-6879(66)08101-1","article-title":"\u03b1-Glucosidase from yeast","volume":"8","author":"Halvorson","year":"1966","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.redox.2022.102590_bib42","doi-asserted-by":"crossref","first-page":"6682","DOI":"10.1002\/pola.23709","article-title":"Stepped association of comb-like and stimuli-responsive graft chitosan copolymer synthesized using ATRP and active ester conjugation methods","volume":"47","author":"Bao","year":"2010","journal-title":"J. Polym. Sci., Polym. Chem. Ed."},{"key":"10.1016\/j.redox.2022.102590_bib43","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/0003-2697(91)90282-X","article-title":"On-line detection of nitric oxide formation in liquid aqueous phase by electron paramagnetic resonance spectroscopy","volume":"199","author":"Mordvintcev","year":"1991","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.redox.2022.102590_bib44","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1074\/jbc.270.1.304","article-title":"Direct measurement of nitric oxide generation in the ischemic heart using electron paramagnetic resonance spectroscopy","volume":"270","author":"Zweier","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.redox.2022.102590_bib45","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1006\/bbrc.1993.2170","article-title":"Vivo spin trapping of nitric oxide in mice","volume":"195","author":"Komarov","year":"1993","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"4","key":"10.1016\/j.redox.2022.102590_bib46","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1136\/gut.42.4.485","article-title":"Impairment of intestinal glutathione synthesis in patients with inflammatory bowel disease","volume":"42","author":"Sido","year":"1998","journal-title":"Gut"},{"issue":"10","key":"10.1016\/j.redox.2022.102590_bib47","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1016\/j.bbamcr.2012.06.019","article-title":"Glutathione and modulation of cell apoptosis","volume":"1823","author":"Circu","year":"2012","journal-title":"Biochim. Biophys. Acta"},{"issue":"12","key":"10.1016\/j.redox.2022.102590_bib48","doi-asserted-by":"crossref","first-page":"4628","DOI":"10.1073\/pnas.0511304103","article-title":"High-dose oral N-acetylcysteine, a glutathione prodrug, modulates inflammation in cystic fibrosis","volume":"103","author":"Tirouvanziam","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"issue":"1","key":"10.1016\/j.redox.2022.102590_bib49","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1039\/c5tx00214a","article-title":"Red wine polyphenol extract efficiently protects intestinal epithelial cells from inflammation via opposite modulation of JAK\/STAT and Nrf2 pathways","volume":"5","author":"Nunes","year":"2015","journal-title":"Toxicol. Res."},{"issue":"22","key":"10.1016\/j.redox.2022.102590_bib50","doi-asserted-by":"crossref","first-page":"6349","DOI":"10.1021\/ja020020w","article-title":"Flash photolytic generation and study of p-quinone methide in aqueous solution. An estimate of rate and equilibrium constants for heterolysis of the carbon-bromine bond in p-hydroxybenzyl bromide","volume":"124","author":"Chiang","year":"2002","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.redox.2022.102590_bib51","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.biomaterials.2015.02.107","article-title":"p-Hydroxybenzyl alcohol-containing biodegradable nanoparticle improves functional blood flow through angiogenesis in a mouse model of hindlimb ischemia","volume":"53","author":"Cho","year":"2015","journal-title":"Biomaterials"},{"key":"10.1016\/j.redox.2022.102590_bib52","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/628157","article-title":"Intestinal permeability in inflammatory bowel disease: pathogenesis, clinical evaluation, and therapy of leaky gut","volume":"2015","author":"Michielan","year":"2015","journal-title":"Mediat. Inflamm."},{"key":"10.1016\/j.redox.2022.102590_bib53","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1097\/SPC.0000000000000017","article-title":"Gut barrier dysfunction and microbial translocation in cancer cachexia: a new therapeutic target","volume":"7","author":"Klein","year":"2013","journal-title":"Curr. Opin. Support. Palliat. Care"},{"key":"10.1016\/j.redox.2022.102590_bib54","article-title":"Gut microbiota in NSAID enteropathy: new insights from inside","volume":"11","author":"Wang","year":"2021","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.redox.2022.102590_bib55","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1038\/nrmicro2546","article-title":"Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis","volume":"9","author":"Bevins","year":"2011","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.redox.2022.102590_bib56","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1053\/j.gastro.2020.11.015","article-title":"Paneth cell alertness to pathogens maintained by vitamin D receptors","volume":"160","author":"Lu","year":"2021","journal-title":"Gastroenterology"}],"container-title":["Redox Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213231722003627?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213231722003627?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T06:28:34Z","timestamp":1761978514000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213231722003627"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2]]},"references-count":56,"alternative-id":["S2213231722003627"],"URL":"https:\/\/doi.org\/10.1016\/j.redox.2022.102590","relation":{},"ISSN":["2213-2317"],"issn-type":[{"value":"2213-2317","type":"print"}],"subject":[],"published":{"date-parts":[[2023,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Targeted delivery of Nitric Oxide triggered by \u03b1-Glucosidase to Ameliorate NSAIDs-induced Enteropathy","name":"articletitle","label":"Article Title"},{"value":"Redox Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.redox.2022.102590","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"102590"}}