{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T01:21:38Z","timestamp":1790558498727,"version":"4.1.0"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,28]],"date-time":"2023-01-28T00:00:00Z","timestamp":1674864000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004063","name":"Knut och Alice Wallenbergs Stiftelse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004063","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016669","name":"Sj\u00f6bergstiftelsen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016669","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018713","name":"Center for Innovative Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100018713","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002794","name":"Cancerfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002794","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Redox Biology"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.redox.2023.102619","type":"journal-article","created":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T14:46:01Z","timestamp":1675349161000},"page":"102619","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":56,"special_numbering":"C","title":["ROS-lowering doses of vitamins C and A accelerate malignant melanoma metastasis"],"prefix":"10.1016","volume":"60","author":[{"given":"Muhammad","family":"Kashif","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haidong","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Schmidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Truong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elin","family":"T\u00fcksammel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiran","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6915-7140","authenticated-orcid":false,"given":"Martin O.","family":"Bergo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.redox.2023.102619_bib1","series-title":"Cancer Treatment and Survivorship Statistics","author":"Miller","year":"2022"},{"key":"10.1016\/j.redox.2023.102619_bib2","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1038\/nature15726","article-title":"Oxidative stress inhibits distant metastasis by human melanoma cells","volume":"527","author":"Piskounova","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.redox.2023.102619_bib3","article-title":"Antioxidants can increase melanoma metastasis in mice","volume":"308","author":"LeGal","year":"2015","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.redox.2023.102619_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.cell.2019.06.005","article-title":"BACH1 stabilization by antioxidants stimulates lung cancer metastasis","volume":"178","author":"Wiel","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.redox.2023.102619_bib5","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.cell.2019.06.003","article-title":"Nrf2 activation promotes lung cancer metastasis by inhibiting the degradation of Bach1","volume":"178","author":"Lignitto","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.redox.2023.102619_bib6","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1038\/s41586-020-2623-z","article-title":"Lymph protects metastasizing melanoma cells from ferroptosis","volume":"585","author":"Ubellacker","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.redox.2023.102619_bib7","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.ccell.2019.12.012","article-title":"Dynamic ROS control by TIGAR regulates the initiation and progression of pancreatic cancer","volume":"37","author":"Cheung","year":"2020","journal-title":"Cancer Cell"},{"key":"10.1016\/j.redox.2023.102619_bib8","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.freeradbiomed.2016.04.198","article-title":"Mitochondrial ROS regulation of proliferating cells","volume":"100","author":"Diebold","year":"2016","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.redox.2023.102619_bib9","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1038\/ng.356","article-title":"Braf(V600E) cooperates with Pten loss to induce metastatic melanoma","volume":"41","author":"Dankort","year":"2009","journal-title":"Nat. Genet."},{"key":"10.1016\/j.redox.2023.102619_bib10","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1016\/S0002-8223(00)00189-9","article-title":"Dietary Reference intakes for the antioxidant nutrients: vitamin C, vitamin E, selenium, and carotenoids (vol 100, pg 638, 2000)","volume":"100","author":"Monsen","year":"2000","journal-title":"J. Am. Diet Assoc."},{"key":"10.1016\/j.redox.2023.102619_bib11","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1093\/bioinformatics\/bts635","article-title":"STAR: ultrafast universal RNA-seq aligner","volume":"29","author":"Dobin","year":"2013","journal-title":"Bioinformatics"},{"key":"10.1016\/j.redox.2023.102619_bib12","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1093\/bioinformatics\/btt656","article-title":"featureCounts: an efficient general purpose program for assigning sequence reads to genomic features","volume":"30","author":"Liao","year":"2014","journal-title":"Bioinformatics"},{"key":"10.1016\/j.redox.2023.102619_bib13","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol."},{"key":"10.1016\/j.redox.2023.102619_bib14","doi-asserted-by":"crossref","first-page":"W191","DOI":"10.1093\/nar\/gkz369","article-title":"g:Profiler: a web server for functional enrichment analysis and conversions of gene lists (2019 update)","volume":"47","author":"Raudvere","year":"2019","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.redox.2023.102619_bib15","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1038\/ng.356","article-title":"Braf(V600E) cooperates with Pten loss to induce metastatic melanoma","volume":"41","author":"Dankort","year":"2009","journal-title":"Nat. Genet."},{"key":"10.1016\/j.redox.2023.102619_bib16","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.3007653","article-title":"Antioxidants accelerate lung cancer progression in mice","volume":"6","author":"Sayin","year":"2014","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.redox.2023.102619_bib17","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1056\/NEJM199404143301501","article-title":"The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers","volume":"330","year":"1994","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.redox.2023.102619_bib18","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1001\/jama.2011.1437","article-title":"Vitamin E and the risk of prostate cancer: the selenium and vitamin E cancer prevention trial (SELECT)","volume":"306","author":"Klein","year":"2011","journal-title":"JAMA"},{"key":"10.1016\/j.redox.2023.102619_bib19","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1093\/jnci\/92.12.977","article-title":"EUROSCAN, a randomized trial of vitamin A and N-acetylcysteine in patients with head and neck cancer or lung cancer","volume":"92","author":"van Zandwijk","year":"2000","journal-title":"JNCI (J. Natl. Cancer Inst.)"},{"key":"10.1016\/j.redox.2023.102619_bib20","doi-asserted-by":"crossref","first-page":"2682","DOI":"10.1158\/2159-8290.CD-21-0558","article-title":"Redox regulation in cancer cells during metastasis","volume":"11","author":"Tasdogan","year":"2021","journal-title":"Cancer Discov."}],"container-title":["Redox Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213231723000204?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213231723000204?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T06:29:14Z","timestamp":1761978554000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213231723000204"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":20,"alternative-id":["S2213231723000204"],"URL":"https:\/\/doi.org\/10.1016\/j.redox.2023.102619","relation":{},"ISSN":["2213-2317"],"issn-type":[{"value":"2213-2317","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"ROS-lowering doses of vitamins C and A accelerate malignant melanoma metastasis","name":"articletitle","label":"Article Title"},{"value":"Redox Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.redox.2023.102619","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"102619"}}