{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T00:19:36Z","timestamp":1793751576020,"version":"4.6.1"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,3,26]],"date-time":"2023-03-26T00:00:00Z","timestamp":1679788800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002367","name":"Chinese Academy of Sciences","doi-asserted-by":"publisher","award":["XDB29010000"],"award-info":[{"award-number":["XDB29010000"]}],"id":[{"id":"10.13039\/501100002367","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002367","name":"Chinese Academy of Sciences","doi-asserted-by":"publisher","award":["XDB29020000"],"award-info":[{"award-number":["XDB29020000"]}],"id":[{"id":"10.13039\/501100002367","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004739","name":"Youth Innovation Promotion Association of the Chinese Academy of Sciences","doi-asserted-by":"publisher","award":["Y201921"],"award-info":[{"award-number":["Y201921"]}],"id":[{"id":"10.13039\/501100004739","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Redox Biology"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1016\/j.redox.2023.102690","type":"journal-article","created":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T12:07:55Z","timestamp":1679918875000},"page":"102690","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":161,"special_numbering":"C","title":["Promotion of astrocyte-neuron glutamate-glutamine shuttle by SCFA contributes to the alleviation of Alzheimer's disease"],"prefix":"10.1016","volume":"62","author":[{"given":"Yan","family":"Sun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huaiwu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenzhao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiyou","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qihui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.redox.2023.102690_bib1","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1038\/461895a","article-title":"Alzheimer's disease","volume":"461","author":"Mucke","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.redox.2023.102690_bib2","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1038\/nrneurol.2018.9","article-title":"Imaging tau and amyloid-beta proteinopathies in Alzheimer disease and other conditions","volume":"14","author":"Villemagne","year":"2018","journal-title":"Nat. Rev. Neurol."},{"key":"10.1016\/j.redox.2023.102690_bib3","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1038\/nature05292","article-title":"Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases","volume":"443","author":"Lin","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.redox.2023.102690_bib4","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S1474-4422(10)70277-5","article-title":"Disrupted energy metabolism and neuronal circuit dysfunction in cognitive impairment and Alzheimer's disease","volume":"10","author":"Kapogiannis","year":"2011","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.redox.2023.102690_bib5","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1093\/brain\/awh451","article-title":"The 9 year cognitive decline before dementia of the Alzheimer type: a prospective population-based study","volume":"128","author":"Amieva","year":"2005","journal-title":"Brain"},{"key":"10.1016\/j.redox.2023.102690_bib6","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S1474-4422(09)70299-6","article-title":"Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade","volume":"9","author":"Jack","year":"2010","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.redox.2023.102690_bib7","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1038\/nrd2896","article-title":"Alzheimer's disease: strategies for disease modification","volume":"9","author":"Citron","year":"2010","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.redox.2023.102690_bib8","doi-asserted-by":"crossref","first-page":"525","DOI":"10.3109\/10715762.2015.1014814","article-title":"Measurement of oxidatively induced DNA damage and its repair, by mass spectrometric techniques","volume":"49","author":"Dizdaroglu","year":"2015","journal-title":"Free Radic. Res."},{"key":"10.1016\/j.redox.2023.102690_bib9","series-title":"Free Radicals in Biology and Medicine","author":"Halliwell","year":"2015"},{"key":"10.1016\/j.redox.2023.102690_bib10","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.3233\/JAD-170543","article-title":"Oxidative stress, amyloid-\u03b2 peptide, and altered key molecular pathways in the pathogenesis and progression of Alzheimer's disease","volume":"62","author":"Butterfield","year":"2018","journal-title":"J Alzheimers Dis"},{"key":"10.1016\/j.redox.2023.102690_bib11","article-title":"A dual-targeted multifunctional nanoformulation for potential prevention and therapy of Alzheimer's disease","volume":"2","author":"Zhao","year":"2021","journal-title":"Innovation"},{"key":"10.1016\/j.redox.2023.102690_bib12","doi-asserted-by":"crossref","DOI":"10.1111\/acel.12679","article-title":"SIRT3 deregulation is linked to mitochondrial dysfunction in Alzheimer's disease","volume":"17","author":"Lee","year":"2018","journal-title":"Aging Cell"},{"key":"10.1016\/j.redox.2023.102690_bib13","article-title":"Can ketones help rescue brain fuel supply in later life? Implications for cognitive health during aging and the treatment of Alzheimer's disease","volume":"53","author":"Cunnane","year":"2016","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.redox.2023.102690_bib14","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1007\/s00702-019-01975-4","article-title":"Dementia spectrum disorders: lessons learnt from decades with PET research","volume":"126","author":"Wilson","year":"2019","journal-title":"J. Neural. Transm."},{"key":"10.1016\/j.redox.2023.102690_bib15","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1016\/j.cell.2019.04.001","article-title":"Neuron-astrocyte metabolic coupling protects against activity-induced fatty acid toxicity","volume":"177","author":"Ioannou","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.redox.2023.102690_bib16","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1038\/nrn.2018.19","article-title":"Lactate in the brain: from metabolic end-product to signalling molecule","volume":"19","author":"Magistretti","year":"2018","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.redox.2023.102690_bib17","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1002\/glia.23316","article-title":"Lia in brain energy metabolism: a perspective","volume":"66","author":"Barros","year":"2018","journal-title":"Glia"},{"key":"10.1016\/j.redox.2023.102690_bib18","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/j.cmet.2011.08.016","article-title":"Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation","volume":"14","author":"B\u00e9langer","year":"2011","journal-title":"Cell Metabol."},{"key":"10.1016\/j.redox.2023.102690_bib19","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1136\/gut.28.10.1221","article-title":"Short chain fatty acids in human large intestine, portal, hepatic and venous blood","volume":"28","author":"Cummings","year":"1987","journal-title":"Gut"},{"key":"10.1016\/j.redox.2023.102690_bib20","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1038\/s41575-019-0157-3","article-title":"The role of short-chain fatty acids in microbiota-gut-brain communication","volume":"16","author":"Dalile","year":"2019","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.redox.2023.102690_bib21","doi-asserted-by":"crossref","first-page":"187","DOI":"10.3233\/JAD-2011-110080","article-title":"Sodium butyrate improves memory function in an Alzheimer's disease mouse model when administered at an advanced stage of disease progression","volume":"26","author":"Govindarajan","year":"2011","journal-title":"J Alzheimers Dis"},{"key":"10.1016\/j.redox.2023.102690_bib22","doi-asserted-by":"crossref","first-page":"91","DOI":"10.3233\/JAD-190120","article-title":"Sodium butyrate reduces brain amyloid-\u03b2 levels and improves cognitive memory performance in an Alzheimer's disease transgenic mouse model at an early disease stage","volume":"74","author":"Fernando","year":"2020","journal-title":"J Alzheimers Dis"},{"key":"10.1016\/j.redox.2023.102690_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbi.2021.109452","article-title":"Sodium butyrate ameliorates the impairment of synaptic plasticity by inhibiting the neuroinflammation in 5XFAD mice","volume":"341","author":"Jiang","year":"2021","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.redox.2023.102690_bib24","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1152\/physrev.1990.70.2.567","article-title":"Energy contributions of volatile fatty acids from the gastrointestinal tract in various species","volume":"70","author":"Bergman","year":"1990","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.redox.2023.102690_bib25","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1038\/s42255-018-0017-4","article-title":"Microbial regulation of organismal energy homeostasis","volume":"1","author":"Cani","year":"2019","journal-title":"Nat Metab"},{"key":"10.1016\/j.redox.2023.102690_bib26","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.addr.2020.01.004","article-title":"Fatty acid metabolism in the progression and resolution of CNS disorders","volume":"159","author":"Bogie","year":"2020","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.redox.2023.102690_bib27","doi-asserted-by":"crossref","first-page":"39211","DOI":"10.1074\/jbc.M110.156026","article-title":"Butyrate-rich colonic microenvironment is a relevant selection factor for metabolically adapted tumor cells","volume":"285","author":"Serpa","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.redox.2023.102690_bib28","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.cmet.2011.02.018","article-title":"The microbiome and butyrate regulate energy metabolism and autophagy in the mammalian colon","volume":"13","author":"Donohoe","year":"2011","journal-title":"Cell Metabol."},{"key":"10.1016\/j.redox.2023.102690_bib29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-022-18363-w","article-title":"Brief exposure of neuronal cells to levels of SCFAs observed in human systemic circulation impair lipid metabolism resulting in apoptosis","volume":"12","author":"Fillier","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.redox.2023.102690_bib30","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1097\/FBP.0b013e32834d0f1b","article-title":"Behavioral and neurochemical effects of sodium butyrate in an animal model of mania","volume":"22","author":"Moretti","year":"2011","journal-title":"Behav. Pharmacol."},{"key":"10.1016\/j.redox.2023.102690_bib31","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.cell.2013.12.016","article-title":"Microbiota-generated metabolites promote metabolic benefits via gut-brain neural circuits","volume":"156","author":"De Vadder","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.redox.2023.102690_bib32","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.cell.2019.02.014","article-title":"Multi-sensory gamma stimulation ameliorates alzheimer's-associated pathology and improves cognition","volume":"177","author":"Martorell","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.redox.2023.102690_bib33","doi-asserted-by":"crossref","first-page":"6129","DOI":"10.1038\/s41467-020-19737-2","article-title":"Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer's disease","volume":"11","author":"Olah","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.redox.2023.102690_bib34","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1038\/s41593-020-0624-8","article-title":"Disease-associated astrocytes in Alzheimer's disease and aging","volume":"23","author":"Habib","year":"2020","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.redox.2023.102690_bib35","doi-asserted-by":"crossref","first-page":"8430","DOI":"10.7150\/thno.44370","article-title":"Modulation of the astrocyte-neuron lactate shuttle system contributes to neuroprotective action of fibroblast growth factor 21","volume":"10","author":"Sun","year":"2020","journal-title":"Theranostics"},{"key":"10.1016\/j.redox.2023.102690_bib36","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.trci.2019.05.008","article-title":"Alzheimer's disease drug development pipeline: 2019","volume":"5","author":"Cummings","year":"2019","journal-title":"Alzheimers Dement (N Y)"},{"key":"10.1016\/j.redox.2023.102690_bib37","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1038\/s41591-020-0815-6","article-title":"Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation","volume":"26","author":"Johnson","year":"2020","journal-title":"Nat. Med."},{"key":"10.1016\/j.redox.2023.102690_bib38","first-page":"1","article-title":"The human brain NGF metabolic pathway is impaired in the pre-clinical and clinical continuum of Alzheimers disease","author":"Pentz","year":"2020","journal-title":"Mol. Psychiatr."},{"key":"10.1016\/j.redox.2023.102690_bib39","doi-asserted-by":"crossref","first-page":"1954","DOI":"10.1016\/j.euroneuro.2014.06.008","article-title":"Type 3 diabetes is sporadic Alzheimer\u05f3 s disease: mini-review","volume":"24","author":"Suzanne","year":"2014","journal-title":"Eur. Neuropsychopharmacol"},{"key":"10.1016\/j.redox.2023.102690_bib40","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1038\/s41583-019-0132-6","article-title":"Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease","volume":"20","author":"Butterfield","year":"2019","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.redox.2023.102690_bib41","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1038\/s41573-020-0072-x","article-title":"Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing","volume":"19","author":"Cunnane","year":"2020","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.redox.2023.102690_bib42","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.exger.2017.07.004","article-title":"A cross-sectional comparison of brain glucose and ketone metabolism in cognitively healthy older adults, mild cognitive impairment and early Alzheimer's disease","volume":"107","author":"Croteau","year":"2018","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.redox.2023.102690_bib43","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.59826","article-title":"Microbiota-derived short chain fatty acids modulate microglia and promote A\u03b2 plaque deposition","volume":"10","author":"Colombo","year":"2021","journal-title":"Elife"},{"key":"10.1016\/j.redox.2023.102690_bib44","doi-asserted-by":"crossref","first-page":"2260","DOI":"10.1016\/j.cmet.2021.10.010","article-title":"Microbiota-derived acetate enables the metabolic fitness of the brain innate immune system during health and disease","volume":"33","author":"Erny","year":"2021","journal-title":"Cell Metabol."},{"key":"10.1016\/j.redox.2023.102690_bib45","doi-asserted-by":"crossref","first-page":"7152","DOI":"10.1021\/acs.jafc.0c02807","article-title":"Anti-neuroinflammatory effect of short-chain fatty acid acetate against alzheimer's disease via upregulating GPR41 and inhibiting ERK\/JNK\/NF-\u03baB","volume":"68","author":"Liu","year":"2020","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.redox.2023.102690_bib46","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1093\/gerona\/glz262","article-title":"Gut microbiota: from the forgotten organ to a potential key player in the pathology of Alzheimer's disease","volume":"75","author":"Seo","year":"2020","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"10.1016\/j.redox.2023.102690_bib47","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/S0896-6273(00)80086-0","article-title":"Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate","volume":"16","author":"Rothstein","year":"1996","journal-title":"Neuron"},{"key":"10.1016\/j.redox.2023.102690_bib48","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1046\/j.1471-4159.2001.00322.x","article-title":"Transfer of glutamine between astrocytes and neurons","volume":"77","author":"Br\u00f6er","year":"2001","journal-title":"J. Neurochem."},{"key":"10.1016\/j.redox.2023.102690_bib49","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1523\/JNEUROSCI.22-01-00062.2002","article-title":"Glutamine uptake by neurons: interaction of protons with system a transporters","volume":"22","author":"Chaudhry","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.redox.2023.102690_bib50","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1002\/glia.22386","article-title":"The system N transporter SN2 doubles as a transmitter precursor furnisher and a potential regulator of NMDA receptors","volume":"60","author":"Hamdani","year":"2012","journal-title":"Glia"},{"key":"10.1016\/j.redox.2023.102690_bib51","doi-asserted-by":"crossref","first-page":"154","DOI":"10.3390\/biomedicines8060154","article-title":"Free fatty acid receptors 2 and 3 as microbial metabolite sensors to shape host health: pharmacophysiological view","volume":"8","author":"Mishra","year":"2020","journal-title":"Biomedicines"},{"key":"10.1016\/j.redox.2023.102690_bib52","doi-asserted-by":"crossref","first-page":"184","DOI":"10.3390\/cells8020184","article-title":"Astrocytes maintain glutamate homeostasis in the CNS by controlling the balance between glutamate uptake and release","volume":"8","author":"Mahmoud","year":"2019","journal-title":"Cells"},{"key":"10.1016\/j.redox.2023.102690_bib53","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/978-3-319-45096-4_13","article-title":"Glutamine synthetase: role in neurological disorders","author":"Jayakumar","year":"2016","journal-title":"Adv Neurobiol"},{"key":"10.1016\/j.redox.2023.102690_bib54","doi-asserted-by":"crossref","DOI":"10.1016\/j.pneurobio.2019.101645","article-title":"Roles of forkhead box O (FoxO) transcription factors in neurodegenerative diseases: a panoramic view","volume":"181","author":"Hu","year":"2019","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.redox.2023.102690_bib55","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.neulet.2015.10.001","article-title":"The nuclear retention of transcription factor FOXO3a correlates with a DNA damage response and increased glutamine synthetase expression by astrocytes suggesting a neuroprotective role in the ageing brain","volume":"609","author":"Fluteau","year":"2015","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.redox.2023.102690_bib56","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1038\/ncb2536","article-title":"Modulation of glutamine metabolism by the PI (3) K\u2013PKB\u2013FOXO network regulates autophagy","volume":"14","author":"Van Der Vos","year":"2012","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.redox.2023.102690_bib57","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.neurobiolaging.2008.05.015","article-title":"Astrocyte phenotype in relation to Alzheimer-type pathology in the ageing brain","volume":"31","author":"Simpson","year":"2010","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.redox.2023.102690_bib58","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1016\/j.neurobiolaging.2011.04.013","article-title":"Microarray analysis of the astrocyte transcriptome in the aging brain: relationship to Alzheimer's pathology and APOE genotype","volume":"32","author":"Simpson","year":"2011","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.redox.2023.102690_bib59","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.bbi.2015.03.006","article-title":"Cytokine-producing microglia have an altered beta-amyloid load in aged APP\/PS1 Tg mice","volume":"48","author":"Babcock","year":"2015","journal-title":"Brain Behav. Immun."}],"container-title":["Redox Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213231723000915?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213231723000915?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T06:32:49Z","timestamp":1761978769000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213231723000915"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":59,"alternative-id":["S2213231723000915"],"URL":"https:\/\/doi.org\/10.1016\/j.redox.2023.102690","relation":{},"ISSN":["2213-2317"],"issn-type":[{"value":"2213-2317","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Promotion of astrocyte-neuron glutamate-glutamine shuttle by SCFA contributes to the alleviation of Alzheimer's disease","name":"articletitle","label":"Article Title"},{"value":"Redox Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.redox.2023.102690","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"102690"}}