{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,8]],"date-time":"2026-11-08T03:11:01Z","timestamp":1794107461962,"version":"4.8.0"},"reference-count":75,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T00:00:00Z","timestamp":1692576000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100008903","name":"Taiwan Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["MOHW112-TDU-B-222-124013"],"award-info":[{"award-number":["MOHW112-TDU-B-222-124013"]}],"id":[{"id":"10.13039\/100008903","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010002","name":"Ministry of Education","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020595","name":"National Science and Technology Council","doi-asserted-by":"publisher","award":["MOST111-2320-B038-053-MY3"],"award-info":[{"award-number":["MOST111-2320-B038-053-MY3"]}],"id":[{"id":"10.13039\/100020595","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020595","name":"National Science and Technology Council","doi-asserted-by":"publisher","award":["MOST111-3111-Y-016-004"],"award-info":[{"award-number":["MOST111-3111-Y-016-004"]}],"id":[{"id":"10.13039\/100020595","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100022424","name":"Republic of Srpska Ministry of Scientific and Technological Development Higher Education and Information Society","doi-asserted-by":"publisher","award":["112-TMU043"],"award-info":[{"award-number":["112-TMU043"]}],"id":[{"id":"10.13039\/501100022424","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100022424","name":"Republic of Srpska Ministry of Scientific and Technological Development Higher Education and Information Society","doi-asserted-by":"publisher","award":["DP2-111-21121-01-C-01-04"],"award-info":[{"award-number":["DP2-111-21121-01-C-01-04"]}],"id":[{"id":"10.13039\/501100022424","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100022424","name":"Republic of Srpska Ministry of Scientific and Technological Development Higher Education and Information Society","doi-asserted-by":"publisher","award":["DP2-TMU-112-C-08"],"award-info":[{"award-number":["DP2-TMU-112-C-08"]}],"id":[{"id":"10.13039\/501100022424","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Redox Biology"],"published-print":{"date-parts":[[2023,10]]},"DOI":"10.1016\/j.redox.2023.102861","type":"journal-article","created":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T09:28:02Z","timestamp":1692955682000},"page":"102861","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"special_numbering":"C","title":["Oxidative stress mediates the inhibitory effects of Manzamine A on uterine leiomyoma cell proliferation and extracellular matrix deposition via SOAT inhibition"],"prefix":"10.1016","volume":"66","author":[{"given":"Li-Chun","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsin-Yi","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tzu-Ting","family":"Kuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsin-Yuan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Shan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yii-Jwu","family":"Lo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shih-Min","family":"Hsia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7873-132X","authenticated-orcid":false,"given":"Tsui-Chin","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.redox.2023.102861_bib1","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1093\/ajcp\/94.4.435","article-title":"The frequency of uterine leiomyomas","volume":"94","author":"Cramer","year":"1990","journal-title":"Am. J. Clin. Pathol."},{"issue":"10","key":"10.1016\/j.redox.2023.102861_bib2","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1111\/1471-0528.14640","article-title":"Epidemiology of uterine fibroids: a systematic review","volume":"124","author":"Stewart","year":"2017","journal-title":"Bjog"},{"issue":"1","key":"10.1016\/j.redox.2023.102861_bib3","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1067\/mob.2003.99","article-title":"High cumulative incidence of uterine leiomyoma in black and white women: ultrasound evidence","volume":"188","author":"Baird","year":"2003","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"2","key":"10.1016\/j.redox.2023.102861_bib4","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1111\/jog.13519","article-title":"Recurrence of uterine myoma after myomectomy: open myomectomy versus laparoscopic myomectomy","volume":"44","author":"Kotani","year":"2018","journal-title":"J. Obstet. Gynaecol. Res."},{"key":"10.1016\/j.redox.2023.102861_bib5","doi-asserted-by":"crossref","DOI":"10.12688\/f1000research.12172.1","article-title":"Uterine fibroids - what's new?","volume":"6","author":"Williams","year":"2017","journal-title":"F1000Research"},{"issue":"3","key":"10.1016\/j.redox.2023.102861_bib6","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1210\/jc.2012-3237","article-title":"Uterine leiomyoma: available medical treatments and new possible therapeutic options","volume":"98","author":"Islam","year":"2013","journal-title":"J. Clin. Endocrinol. Metabol."},{"issue":"1","key":"10.1016\/j.redox.2023.102861_bib7","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1093\/humupd\/dmx032","article-title":"Extracellular matrix in uterine leiomyoma pathogenesis: a potential target for future therapeutics","volume":"24","author":"Islam","year":"2018","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.redox.2023.102861_bib8","article-title":"Uterine fibroids","volume":"2","author":"Stewart","year":"2016","journal-title":"Nat. Rev. Dis. Prim."},{"issue":"5","key":"10.1016\/j.redox.2023.102861_bib9","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1093\/humupd\/dmv030","article-title":"Epidemiological and genetic clues for molecular mechanisms involved in uterine leiomyoma development and growth","volume":"21","author":"Commandeur","year":"2015","journal-title":"Hum. Reprod. Update"},{"issue":"2","key":"10.1016\/j.redox.2023.102861_bib10","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1177\/1933719115584449","article-title":"The mechanism and function of epigenetics in uterine leiomyoma development","volume":"23","author":"Yang","year":"2016","journal-title":"Reprod. Sci."},{"issue":"7","key":"10.1016\/j.redox.2023.102861_bib11","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.3390\/ijms19072051","article-title":"Vitamin D and uterine fibroids-review of the literature and novel concepts","volume":"19","author":"Ciebiera","year":"2018","journal-title":"Int. J. Mol. Sci."},{"issue":"9","key":"10.1016\/j.redox.2023.102861_bib12","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.1093\/humrep\/det265","article-title":"Vitamin D3 inhibits expression and activities of matrix metalloproteinase-2 and -9 in human uterine fibroid cells","volume":"28","author":"Halder","year":"2013","journal-title":"Hum. Reprod."},{"issue":"4","key":"10.1016\/j.redox.2023.102861_bib13","first-page":"99","article-title":"Natural antioxidant resveratrol suppresses uterine fibroid cell growth and extracellular matrix formation in vitro and in vivo","volume":"8","author":"Chen","year":"2019","journal-title":"Antioxidants (Basel, Switzerland)"},{"key":"10.1016\/j.redox.2023.102861_bib14","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.jff.2016.02.038","article-title":"Resveratrol inhibits proliferation of myometrial and leiomyoma cells and decreases extracellular matrix-associated protein expression","volume":"23","author":"Wu","year":"2016","journal-title":"J. Funct.Foods"},{"issue":"3","key":"10.1016\/j.redox.2023.102861_bib15","doi-asserted-by":"crossref","first-page":"289.e1","DOI":"10.1016\/j.ajog.2009.10.885","article-title":"Green tea extract inhibits proliferation of uterine leiomyoma cells in vitro and in nude mice","volume":"202","author":"Zhang","year":"2010","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"5","key":"10.1016\/j.redox.2023.102861_bib16","doi-asserted-by":"crossref","first-page":"1970","DOI":"10.1159\/000493660","article-title":"Fucoidan inhibits the proliferation of leiomyoma cells and decreases extracellular matrix-associated protein expression","volume":"49","author":"Chen","year":"2018","journal-title":"Cell. Physiol. Biochem."},{"issue":"2","key":"10.1016\/j.redox.2023.102861_bib17","doi-asserted-by":"crossref","first-page":"41","DOI":"10.3390\/md16020041","article-title":"Marine compounds and cancer: 2017 updates","volume":"16","author":"Dyshlovoy","year":"2018","journal-title":"Mar. Drugs"},{"issue":"20","key":"10.1016\/j.redox.2023.102861_bib18","doi-asserted-by":"crossref","first-page":"6404","DOI":"10.1021\/ja00280a055","article-title":"Manzamine A, a novel antitumor alkaloid from a sponge","volume":"108","author":"Sakai","year":"1986","journal-title":"J. Am. Chem. Soc."},{"issue":"5","key":"10.1016\/j.redox.2023.102861_bib19","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1007\/s10637-010-9422-6","article-title":"A novel activity from an old compound: manzamine A reduces the metastatic potential of AsPC-1 pancreatic cancer cells and sensitizes them to TRAIL-induced apoptosis","volume":"29","author":"Guzm\u00e1n","year":"2011","journal-title":"Invest. N. Drugs"},{"issue":"12","key":"10.1016\/j.redox.2023.102861_bib20","doi-asserted-by":"crossref","DOI":"10.3390\/cancers10120503","article-title":"Transporter and lysosomal mediated (Multi)drug resistance to tyrosine kinase inhibitors and potential strategies to overcome resistance","volume":"10","author":"De Klerk","year":"2018","journal-title":"Cancers"},{"issue":"8","key":"10.1016\/j.redox.2023.102861_bib21","doi-asserted-by":"crossref","first-page":"252","DOI":"10.3390\/md16080252","article-title":"Manzamine A exerts anticancer activity against human colorectal cancer cells","volume":"16","author":"Lin","year":"2018","journal-title":"Mar. Drugs"},{"issue":"6","key":"10.1016\/j.redox.2023.102861_bib22","first-page":"1568","article-title":"Rodent model of reproductive tract leiomyomata. Establishment and characterization of tumor-derived cell lines","volume":"146","author":"Howe","year":"1995","journal-title":"Am. J. Pathol."},{"issue":"1","key":"10.1016\/j.redox.2023.102861_bib23","doi-asserted-by":"crossref","first-page":"e3128","DOI":"10.21769\/BioProtoc.3128","article-title":"Analysis of the mitochondrial membrane potential using the cationic JC-1 dye as a sensitive fluorescent probe","volume":"9","author":"Sivandzade","year":"2019","journal-title":"Bio Protoc."},{"key":"10.1016\/j.redox.2023.102861_bib24","first-page":"163","article-title":"Assessment of gelatinases (MMP-2 and MMP-9 by gelatin zymography","volume":"57","author":"Toth","year":"2001","journal-title":"Methods Mol. Med."},{"issue":"12","key":"10.1016\/j.redox.2023.102861_bib25","doi-asserted-by":"crossref","first-page":"2301","DOI":"10.1038\/nprot.2016.136","article-title":"The MaxQuant computational platform for mass spectrometry-based shotgun proteomics","volume":"11","author":"Tyanova","year":"2016","journal-title":"Nat. Protoc."},{"issue":"9","key":"10.1016\/j.redox.2023.102861_bib26","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1038\/nmeth.3901","article-title":"The Perseus computational platform for comprehensive analysis of (prote)omics data","volume":"13","author":"Tyanova","year":"2016","journal-title":"Nat. Methods"},{"issue":"2","key":"10.1016\/j.redox.2023.102861_bib27","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1021\/acs.jproteome.8b00523","article-title":"NormalyzerDE: online tool for improved normalization of omics expression data and high-sensitivity differential expression analysis","volume":"18","author":"Willforss","year":"2019","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.redox.2023.102861_bib28","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1186\/1471-2105-14-128","article-title":"Enrichr: Interactive and collaborative HTML5 gene list enrichment analysis tool","volume":"14","author":"Chen","year":"2013","journal-title":"BMC Bioinf."},{"issue":"11","key":"10.1016\/j.redox.2023.102861_bib29","doi-asserted-by":"crossref","first-page":"4996","DOI":"10.1210\/endo.136.11.7588234","article-title":"Estrogen stimulation and tamoxifen inhibition of leiomyoma cell growth in vitro and in vivo","volume":"136","author":"Howe","year":"1995","journal-title":"Endocrinology"},{"issue":"1\u20132","key":"10.1016\/j.redox.2023.102861_bib30","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0303-7207(02)00230-7","article-title":"Transdominant suppression of estrogen receptor signaling by progesterone receptor ligands in uterine leiomyoma cells","volume":"196","author":"Hodges","year":"2002","journal-title":"Mol. Cell. Endocrinol."},{"issue":"4","key":"10.1016\/j.redox.2023.102861_bib31","doi-asserted-by":"crossref","DOI":"10.3390\/ma12040569","article-title":"Electrospun polylactic acid (PLLA) microtube array membrane (MTAM)-An advanced substrate for anticancer drug screening","volume":"12","author":"Tseng","year":"2019","journal-title":"Materials (Basel)"},{"issue":"5","key":"10.1016\/j.redox.2023.102861_bib32","article-title":"Microtube array membrane (MTAM)-Based encapsulated cell therapy for cancer treatment","volume":"10","author":"Chew","year":"2020","journal-title":"Membranes (Basel)"},{"issue":"2","key":"10.1016\/j.redox.2023.102861_bib33","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1177\/1933719118768692","article-title":"Regulation of cell cycle regulatory proteins by MicroRNAs in uterine leiomyoma","volume":"26","author":"Chuang","year":"2019","journal-title":"Reprod. Sci."},{"issue":"8","key":"10.1016\/j.redox.2023.102861_bib34","doi-asserted-by":"crossref","first-page":"2646","DOI":"10.1016\/j.fertnstert.2009.03.100","article-title":"Changes related to phosphatidylinositol 3-kinase\/Akt signaling in leiomyomas: possible involvement of glycogen synthase kinase 3alpha and cyclin D2 in the pathophysiology","volume":"93","author":"Karra","year":"2010","journal-title":"Fertil. Steril."},{"issue":"9","key":"10.1016\/j.redox.2023.102861_bib35","doi-asserted-by":"crossref","first-page":"3500","DOI":"10.3390\/md11093500","article-title":"The marine natural product manzamine A targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells","volume":"11","author":"Kallifatidis","year":"2013","journal-title":"Mar. Drugs"},{"issue":"2","key":"10.1016\/j.redox.2023.102861_bib36","doi-asserted-by":"crossref","first-page":"124","DOI":"10.7150\/ijms.21856","article-title":"Analysis of MED12 mutation in multiple uterine leiomyomas in South Korean patients","volume":"15","author":"Lee","year":"2018","journal-title":"Int. J. Med. Sci."},{"issue":"1","key":"10.1016\/j.redox.2023.102861_bib37","doi-asserted-by":"crossref","first-page":"E1","DOI":"10.1152\/ajpendo.90926.2008","article-title":"Acyl-coenzyme A:cholesterol acyltransferases","volume":"297","author":"Chang","year":"2009","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.redox.2023.102861_bib38","first-page":"2020","article-title":"FADS2-mediated fatty acid desaturation and cholesterol esterification are signatures of metabolic reprogramming during melanoma progression","author":"Lee","year":"2020","journal-title":"bioRxiv"},{"issue":"6","key":"10.1016\/j.redox.2023.102861_bib39","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1158\/1541-7786.MCR-17-0665","article-title":"Cholesterol esterification inhibition suppresses prostate cancer metastasis by impairing the Wnt\/\u03b2-catenin pathway","volume":"16","author":"Lee","year":"2018","journal-title":"Mol. Cancer Res. : MCR"},{"issue":"5","key":"10.1016\/j.redox.2023.102861_bib40","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/j.cellsig.2007.10.031","article-title":"The first five years of the Wnt targetome","volume":"20","author":"Vlad","year":"2008","journal-title":"Cell. Signal."},{"issue":"9","key":"10.1016\/j.redox.2023.102861_bib41","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1080\/09513590701557416","article-title":"Activity of matrix metalloproteinase-2 and -9 and contents of their tissue inhibitors in uterine leiomyoma and corresponding myometrium","volume":"23","author":"Bogusiewicz","year":"2007","journal-title":"Gynecol. Endocrinol."},{"issue":"3","key":"10.1016\/j.redox.2023.102861_bib42","first-page":"435","article-title":"Lipid droplets and the management of cellular stress","volume":"92","author":"Jarc","year":"2019","journal-title":"Yale J. Biol. Med."},{"key":"10.1016\/j.redox.2023.102861_bib43","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.semcdb.2017.05.023","article-title":"ROS signalling in the biology of cancer","volume":"80","author":"Moloney","year":"2018","journal-title":"Semin. Cell Dev. Biol."},{"issue":"3","key":"10.1016\/j.redox.2023.102861_bib44","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.freeradbiomed.2008.04.029","article-title":"Fatty acids as modulators of the cellular production of reactive oxygen species","volume":"45","author":"Sch\u00f6nfeld","year":"2008","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.redox.2023.102861_bib45","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/978-1-60761-411-1_4","article-title":"Identification of ROS using oxidized DCFDA and flow-cytometry","volume":"594","author":"Eruslanov","year":"2010","journal-title":"Methods Mol. Biol."},{"issue":"2","key":"10.1016\/j.redox.2023.102861_bib46","doi-asserted-by":"crossref","first-page":"109","DOI":"10.4161\/cbt.9.2.10583","article-title":"N-acetylcysteine, reactive oxygen species and beyond","volume":"9","author":"Sun","year":"2010","journal-title":"Cancer Biol. Ther."},{"issue":"3","key":"10.1016\/j.redox.2023.102861_bib47","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/S0165-0173(97)00045-3","article-title":"Neurodegenerative disorders in humans: the role of glutathione in oxidative stress-mediated neuronal death","volume":"25","author":"Bains","year":"1997","journal-title":"Brain Res. Brain Res. Rev."},{"key":"10.1016\/j.redox.2023.102861_bib48","doi-asserted-by":"crossref","DOI":"10.1186\/2049-3002-2-17","article-title":"Mitochondrial reactive oxygen species and cancer","volume":"2","author":"Sullivan","year":"2014","journal-title":"Cancer Metabol."},{"key":"10.1016\/j.redox.2023.102861_bib49","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.semcancer.2017.04.005","article-title":"Mitochondrial ROS control of cancer","volume":"47","author":"Idelchik","year":"2017","journal-title":"Semin. Cancer Biol."},{"issue":"3","key":"10.1016\/j.redox.2023.102861_bib50","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.cmet.2014.01.019","article-title":"Cholesteryl ester accumulation induced by PTEN loss and PI3K\/AKT activation underlies human prostate cancer aggressiveness","volume":"19","author":"Yue","year":"2014","journal-title":"Cell Metabol."},{"issue":"50","key":"10.1016\/j.redox.2023.102861_bib51","doi-asserted-by":"crossref","first-page":"6378","DOI":"10.1038\/onc.2016.168","article-title":"Abrogating cholesterol esterification suppresses growth and metastasis of pancreatic cancer","volume":"35","author":"Li","year":"2016","journal-title":"Oncogene"},{"issue":"3","key":"10.1016\/j.redox.2023.102861_bib52","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1038\/ncb0311-184","article-title":"Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress","volume":"13","author":"Tabas","year":"2011","journal-title":"Nat. Cell Biol."},{"issue":"6059","key":"10.1016\/j.redox.2023.102861_bib53","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1126\/science.1209038","article-title":"The unfolded protein response: from stress pathway to homeostatic regulation","volume":"334","author":"Walter","year":"2011","journal-title":"Science"},{"key":"10.1016\/j.redox.2023.102861_bib54","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1038\/nrm3270","article-title":"The unfolded protein response: controlling cell fate decisions under ER stress and beyond","volume":"13","author":"Hetz","year":"2012","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"4","key":"10.1016\/j.redox.2023.102861_bib55","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.ymeth.2004.10.010","article-title":"The ER chaperone and signaling regulator GRP78\/BiP as a monitor of endoplasmic reticulum stress","volume":"35","author":"Lee","year":"2005","journal-title":"Methods"},{"issue":"12","key":"10.1016\/j.redox.2023.102861_bib56","doi-asserted-by":"crossref","first-page":"3460","DOI":"10.1016\/j.bbamcr.2013.06.028","article-title":"ER stress-induced cell death mechanisms","volume":"1833","author":"Sano","year":"2013","journal-title":"Biochim. Biophys. Acta Mol. Cell Res."},{"issue":"Suppl 2","key":"10.1016\/j.redox.2023.102861_bib57","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1111\/j.1463-1326.2010.01282.x","article-title":"Restoring endoplasmic reticulum function by chemical chaperones: an emerging therapeutic approach for metabolic diseases","volume":"12","author":"Engin","year":"2010","journal-title":"Diabetes Obes. Metabol."},{"issue":"3","key":"10.1016\/j.redox.2023.102861_bib58","doi-asserted-by":"crossref","DOI":"10.1177\/1559325818782631","article-title":"Tauroursodeoxycholic acid alleviates H2O2-induced oxidative stress and apoptosis via suppressing endoplasmic reticulum stress in neonatal rat cardiomyocytes","volume":"16","author":"Zhang","year":"2018","journal-title":"Dose Response"},{"issue":"10","key":"10.1016\/j.redox.2023.102861_bib59","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1016\/j.jvir.2014.05.012","article-title":"Incidence of additional treatments in women treated with MR-guided focused US for symptomatic uterine fibroids: review of 138 patients with an average follow-up of 2.8 years","volume":"25","author":"Gorny","year":"2014","journal-title":"J. Vasc. Intervent. Radiol."},{"issue":"2","key":"10.1016\/j.redox.2023.102861_bib60","doi-asserted-by":"crossref","first-page":"83","DOI":"10.4103\/0975-7406.171700","article-title":"Exploring the ocean for new drug developments: marine pharmacology","volume":"8","author":"Malve","year":"2016","journal-title":"J. Pharm. BioAllied Sci."},{"issue":"4","key":"10.1016\/j.redox.2023.102861_bib61","doi-asserted-by":"crossref","first-page":"2327","DOI":"10.3390\/md13042327","article-title":"Fucoidan and cancer: a multifunctional molecule with anti-tumor potential","volume":"13","author":"Atashrazm","year":"2015","journal-title":"Mar. Drugs"},{"issue":"Pt 3","key":"10.1016\/j.redox.2023.102861_bib62","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1042\/BJ20051417","article-title":"Human acyl-CoA:cholesterol acyltransferase 2 gene expression in intestinal Caco-2 cells and in hepatocellular carcinoma","volume":"394","author":"Song","year":"2006","journal-title":"Biochem. J."},{"issue":"6","key":"10.1016\/j.redox.2023.102861_bib63","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1093\/jmcb\/mjt039","article-title":"A specific cholesterol metabolic pathway is established in a subset of HCCs for tumor growth","volume":"5","author":"Lu","year":"2013","journal-title":"J. Mol. Cell Biol."},{"issue":"6","key":"10.1016\/j.redox.2023.102861_bib64","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1007\/s13402-017-0342-8","article-title":"Leptin promotes the migration and invasion of breast cancer cells by upregulating ACAT2","volume":"40","author":"Huang","year":"2017","journal-title":"Cell. Oncol."},{"issue":"9","key":"10.1016\/j.redox.2023.102861_bib65","doi-asserted-by":"crossref","first-page":"5349","DOI":"10.1210\/jc.2005-0272","article-title":"Overexpression of the Wnt5b gene in leiomyoma cells: implications for a role of the Wnt signaling pathway in the uterine benign tumor","volume":"90","author":"Mangioni","year":"2005","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"4","key":"10.1016\/j.redox.2023.102861_bib66","doi-asserted-by":"crossref","first-page":"e1517","DOI":"10.1210\/clinem\/dgz227","article-title":"Activation of \u03b2-catenin signaling and its crosstalk with estrogen and histone deacetylases in human uterine fibroids","volume":"105","author":"Ali","year":"2020","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"42","key":"10.1016\/j.redox.2023.102861_bib67","doi-asserted-by":"crossref","first-page":"17053","DOI":"10.1073\/pnas.1313650110","article-title":"Paracrine activation of WNT\/\u03b2-catenin pathway in uterine leiomyoma stem cells promotes tumor growth","volume":"110","author":"Ono","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.redox.2023.102861_bib68","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.freeradbiomed.2015.08.030","article-title":"Redox signaling: potential arbitrator of autophagy and apoptosis in therapeutic response","volume":"89","author":"Zhang","year":"2015","journal-title":"Free Radic. Biol. Med."},{"issue":"8","key":"10.1016\/j.redox.2023.102861_bib69","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.3390\/molecules23081941","article-title":"Lipid droplets in cancer: guardians of fat in a stressful world","volume":"23","author":"Petan","year":"2018","journal-title":"Molecules"},{"issue":"5","key":"10.1016\/j.redox.2023.102861_bib70","doi-asserted-by":"crossref","DOI":"10.1042\/BSR20180764","article-title":"Dropping in on lipid droplets: insights into cellular stress and cancer","volume":"38","author":"Shyu","year":"2018","journal-title":"Biosci. Rep."},{"issue":"3","key":"10.1016\/j.redox.2023.102861_bib71","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.bbalip.2017.12.006","article-title":"Lipid droplets induced by secreted phospholipase A(2) and unsaturated fatty acids protect breast cancer cells from nutrient and lipotoxic stress","volume":"1863","author":"Jarc","year":"2018","journal-title":"Biochim. Biophys. Acta Mol. Cell Biol. Lipids"},{"key":"10.1016\/j.redox.2023.102861_bib72","article-title":"Plin5 alleviates myocardial ischaemia\/reperfusion injury by reducing oxidative stress through inhibiting the lipolysis of lipid droplets","volume":"7","author":"Zheng","year":"2017","journal-title":"Sci. Rep."},{"issue":"3","key":"10.1016\/j.redox.2023.102861_bib73","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1007\/s10549-009-0594-8","article-title":"High ACAT1 expression in estrogen receptor negative basal-like breast cancer cells is associated with LDL-induced proliferation","volume":"122","author":"Antalis","year":"2010","journal-title":"Breast Cancer Res. Treat."},{"issue":"4","key":"10.1016\/j.redox.2023.102861_bib74","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1111\/j.1365-2184.2011.00758.x","article-title":"Cholesterol esters as growth regulators of lymphocytic leukaemia cells","volume":"44","author":"Mulas","year":"2011","journal-title":"Cell Prolif."},{"issue":"21","key":"10.1016\/j.redox.2023.102861_bib75","doi-asserted-by":"crossref","first-page":"5337","DOI":"10.1158\/1078-0432.CCR-15-2973","article-title":"Inhibition of SOAT1 suppresses glioblastoma growth via blocking SREBP-1-mediated lipogenesis","volume":"22","author":"Geng","year":"2016","journal-title":"Clin. Cancer Res. : Off. J. Am. Assoc. Canc. Res."}],"container-title":["Redox Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213231723002628?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213231723002628?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T03:00:53Z","timestamp":1720666853000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213231723002628"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":75,"alternative-id":["S2213231723002628"],"URL":"https:\/\/doi.org\/10.1016\/j.redox.2023.102861","relation":{},"ISSN":["2213-2317"],"issn-type":[{"value":"2213-2317","type":"print"}],"subject":[],"published":{"date-parts":[[2023,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Oxidative stress mediates the inhibitory effects of Manzamine A on uterine leiomyoma cell proliferation and extracellular matrix deposition via SOAT inhibition","name":"articletitle","label":"Article Title"},{"value":"Redox Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.redox.2023.102861","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"102861"}}