{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T01:28:51Z","timestamp":1792718931272,"version":"4.5.0"},"reference-count":49,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,21]],"date-time":"2025-04-21T00:00:00Z","timestamp":1745193600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82472757"],"award-info":[{"award-number":["82472757"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82073053"],"award-info":[{"award-number":["82073053"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100015401","name":"Shaanxi Province Key Research and Development Projects","doi-asserted-by":"publisher","award":["2024SF-YBXM-057"],"award-info":[{"award-number":["2024SF-YBXM-057"]}],"id":[{"id":"10.13039\/501100015401","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012659","name":"Foundation for Innovative Research Groups of the National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013101","name":"Scientific Research Plan Projects of Shaanxi Education Department","doi-asserted-by":"publisher","award":["24JK0647"],"award-info":[{"award-number":["24JK0647"]}],"id":[{"id":"10.13039\/501100013101","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017596","name":"Natural Science Basic Research Program of Shaanxi Province","doi-asserted-by":"publisher","award":["2024JC-YBMS-720"],"award-info":[{"award-number":["2024JC-YBMS-720"]}],"id":[{"id":"10.13039\/501100017596","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012270","name":"Shaanxi Key Science and Technology Innovation Team Project","doi-asserted-by":"publisher","award":["2023-CX-TD-67"],"award-info":[{"award-number":["2023-CX-TD-67"]}],"id":[{"id":"10.13039\/501100012270","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012270","name":"Shaanxi Key Science and Technology Innovation Team Project","doi-asserted-by":"publisher","award":["2022TD-47"],"award-info":[{"award-number":["2022TD-47"]}],"id":[{"id":"10.13039\/501100012270","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009103","name":"Education Department of Shaanxi Provincial government","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009103","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Redox Biology"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.redox.2025.103647","type":"journal-article","created":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T01:00:47Z","timestamp":1746061247000},"page":"103647","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["FTO facilitates colorectal cancer chemoresistance via regulation of NUPR1-dependent iron homeostasis"],"prefix":"10.1016","volume":"83","author":[{"given":"Changwei","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tong","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shisen","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruxin","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi","family":"Geng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minmin","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianyong","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3272-2385","authenticated-orcid":false,"given":"Liangliang","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuan","family":"Qu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.redox.2025.103647_bib1","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1016\/S0140-6736(19)32319-0","volume":"394","author":"Dekker","year":"2019","journal-title":"Colorectal cancer. Lancet (London, England)"},{"issue":"1","key":"10.1016\/j.redox.2025.103647_bib2","first-page":"12","article-title":"Cancer statistics","volume":"74","author":"Siegel","year":"2024","journal-title":"CA Cancer J. Clin."},{"issue":"4","key":"10.1016\/j.redox.2025.103647_bib3","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1093\/annonc\/mdu543","article-title":"Intensive follow-up strategies improve outcomes in nonmetastatic colorectal cancer patients after curative surgery: a systematic review and meta-analysis","volume":"26","author":"Pita-Fern\u00e1ndez","year":"2015","journal-title":"Ann. Oncol. : Official Journal of the European Society For Medical Oncology"},{"issue":"8","key":"10.1016\/j.redox.2025.103647_bib4","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1097\/00001813-200109000-00001","article-title":"Capecitabine: a novel agent for the treatment of solid tumors","volume":"12","author":"Johnston","year":"2001","journal-title":"Anti Cancer Drugs"},{"issue":"10","key":"10.1016\/j.redox.2025.103647_bib5","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1038\/s41580-019-0168-5","article-title":"Reading, writing and erasing mRNA methylation","volume":"20","author":"Zaccara","year":"2019","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"1","key":"10.1016\/j.redox.2025.103647_bib6","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1186\/s12943-020-01204-7","article-title":"The potential role of RNA N6-methyladenosine in Cancer progression","volume":"19","author":"Wang","year":"2020","journal-title":"Mol. Cancer"},{"issue":"1","key":"10.1016\/j.redox.2025.103647_bib7","doi-asserted-by":"crossref","first-page":"1716","DOI":"10.1038\/s41467-021-21758-4","article-title":"FTO-mediated cytoplasmic m(6)A(m) demethylation adjusts stem-like properties in colorectal cancer cell","volume":"12","author":"Relier","year":"2021","journal-title":"Nat. Commun."},{"issue":"2","key":"10.1016\/j.redox.2025.103647_bib8","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1002\/bab.2536","article-title":"FTO-mediated ZNF687 accelerates tumor growth, metastasis, and angiogenesis in colorectal cancer through the Wnt\/beta-catenin pathway","volume":"71","author":"Li","year":"2024","journal-title":"Biotechnol. Appl. Biochem."},{"issue":"2","key":"10.1016\/j.redox.2025.103647_bib9","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.ymthe.2022.10.012","article-title":"N6-methyladenosine demethylase FTO enhances chemo-resistance in colorectal cancer through SIVA1-mediated apoptosis","volume":"31","author":"Lin","year":"2023","journal-title":"Mol. Ther. : the Journal of the American Society of Gene Therapy"},{"issue":"3","key":"10.1016\/j.redox.2025.103647_bib10","doi-asserted-by":"crossref","DOI":"10.1002\/ctm2.772","article-title":"FTO promotes colorectal cancer progression and chemotherapy resistance via demethylating G6PD\/PARP1","volume":"12","author":"Wang","year":"2022","journal-title":"Clin. Transl. Med."},{"issue":"2","key":"10.1016\/j.redox.2025.103647_bib11","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1038\/s41580-023-00648-1","article-title":"Mechanisms controlling cellular and systemic iron homeostasis","volume":"25","author":"Galy","year":"2024","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"7754","key":"10.1016\/j.redox.2025.103647_bib12","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1038\/s41586-019-1151-1","article-title":"Synthesis and breakdown of universal metabolic precursors promoted by iron","volume":"569","author":"Muchowska","year":"2019","journal-title":"Nature"},{"issue":"6501","key":"10.1016\/j.redox.2025.103647_bib13","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1126\/science.aaz2193","article-title":"Cancer cells deploy lipocalin-2 to collect limiting iron in leptomeningeal metastasis","volume":"369","author":"Chi","year":"2020","journal-title":"Science"},{"issue":"3","key":"10.1016\/j.redox.2025.103647_bib14","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.tcb.2022.11.003","article-title":"Targeting ferroptosis to treat colorectal cancer","volume":"33","author":"Yan","year":"2023","journal-title":"Trends Cell Biol."},{"issue":"8","key":"10.1016\/j.redox.2025.103647_bib15","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1038\/s41416-023-02149-6","article-title":"Ferroptosis in colorectal cancer: a future target?","volume":"128","author":"Yan","year":"2023","journal-title":"Br. J. Cancer"},{"issue":"10","key":"10.1016\/j.redox.2025.103647_bib16","doi-asserted-by":"crossref","first-page":"3773","DOI":"10.7150\/ijbs.96828","article-title":"Ferroptosis: the balance between death and survival in colorectal cancer","volume":"20","author":"Fan","year":"2024","journal-title":"Int. J. Biol. Sci."},{"issue":"1","key":"10.1016\/j.redox.2025.103647_bib17","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1038\/s41467-021-20904-2","article-title":"NUPR1 is a critical repressor of ferroptosis","volume":"12","author":"Liu","year":"2021","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.redox.2025.103647_bib18","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1186\/s12943-024-02030-x","article-title":"CircPIAS1 promotes hepatocellular carcinoma progression by inhibiting ferroptosis via the miR-455-3p\/NUPR1\/FTH1 axis","volume":"23","author":"Zhang","year":"2024","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.redox.2025.103647_bib19","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2020.553045","article-title":"m(6)A reader HNRNPA2B1 promotes Esophageal cancer progression via up-regulation of ACLY and ACC1","volume":"10","author":"Guo","year":"2020","journal-title":"Front. Oncol."},{"key":"10.1016\/j.redox.2025.103647_bib20","article-title":"HNRNPA2B1, as a m(6)A reader, promotes tumorigenesis and metastasis of oral squamous cell carcinoma","volume":"11","author":"Zhu","year":"2021","journal-title":"Front. Oncol."},{"issue":"1","key":"10.1016\/j.redox.2025.103647_bib21","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1186\/s12935-021-01898-9","article-title":"Morphological and molecular characteristics of spheroid formation in HT-29 and Caco-2 colorectal cancer cell lines","volume":"21","author":"Gheytanchi","year":"2021","journal-title":"Cancer Cell Int."},{"issue":"1","key":"10.1016\/j.redox.2025.103647_bib22","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1186\/s12943-022-01555-3","article-title":"Interaction of lncRNA MIR100HG with hnRNPA2B1 facilitates m(6)A-dependent stabilization of TCF7L2 mRNA and colorectal cancer progression","volume":"21","author":"Liu","year":"2022","journal-title":"Mol. Cancer"},{"issue":"4","key":"10.1016\/j.redox.2025.103647_bib23","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1093\/neuonc\/noad233","article-title":"Cholesterol homeostasis confers glioma malignancy triggered by hnRNPA2B1-dependent regulation of SREBP2 and LDLR","volume":"26","author":"Zhang","year":"2024","journal-title":"Neuro Oncol."},{"issue":"6","key":"10.1016\/j.redox.2025.103647_bib24","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1038\/s41418-019-0461-z","article-title":"IGF2BP2 regulates DANCR by serving as an N6-methyladenosine reader","volume":"27","author":"Hu","year":"2020","journal-title":"Cell Death Differ."},{"issue":"2","key":"10.1016\/j.redox.2025.103647_bib25","doi-asserted-by":"crossref","first-page":"e86","DOI":"10.1038\/oncsis.2013.48","article-title":"Tumor suppressor NDRG2 tips the balance of oncogenic TGF-beta via EMT inhibition in colorectal cancer","volume":"3","author":"Shen","year":"2014","journal-title":"Oncogenesis"},{"issue":"13","key":"10.1016\/j.redox.2025.103647_bib26","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1038\/s41388-017-0118-7","article-title":"NDRG2 facilitates colorectal cancer differentiation through the regulation of Skp2-p21\/p27 axis","volume":"37","author":"Shen","year":"2018","journal-title":"Oncogene"},{"issue":"4","key":"10.1016\/j.redox.2025.103647_bib27","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20210739","article-title":"Ferrous iron-activatable drug conjugate achieves potent MAPK blockade in KRAS-driven tumors","volume":"219","author":"Jiang","year":"2022","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.redox.2025.103647_bib28","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms12626","article-title":"YTHDF2 destabilizes m(6)A-containing RNA through direct recruitment of the CCR4-NOT deadenylase complex","volume":"7","author":"Du","year":"2016","journal-title":"Nat. Commun."},{"issue":"7481","key":"10.1016\/j.redox.2025.103647_bib29","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1038\/nature12730","article-title":"N6-methyladenosine-dependent regulation of messenger RNA stability","volume":"505","author":"Wang","year":"2014","journal-title":"Nature"},{"issue":"6","key":"10.1016\/j.redox.2025.103647_bib30","doi-asserted-by":"crossref","first-page":"2500","DOI":"10.1172\/JCI127223","article-title":"Ligand-based design identifies a potent NUPR1 inhibitor exerting anticancer activity via necroptosis","volume":"129","author":"Santofimia-Castano","year":"2019","journal-title":"J. Clin. Investig."},{"issue":"12","key":"10.1016\/j.redox.2025.103647_bib31","doi-asserted-by":"crossref","DOI":"10.3390\/cancers14122928","article-title":"Drug resistance in colorectal cancer: from mechanism to clinic","volume":"14","author":"Wang","year":"2022","journal-title":"Cancers (Basel)"},{"issue":"8","key":"10.1016\/j.redox.2025.103647_bib32","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1136\/gutjnl-2022-328845","article-title":"Targeting m(6)A reader YTHDF1 augments antitumour immunity and boosts anti-PD-1 efficacy in colorectal cancer","volume":"72","author":"Bao","year":"2023","journal-title":"Gut"},{"issue":"4","key":"10.1016\/j.redox.2025.103647_bib33","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1053\/j.gastro.2022.06.024","article-title":"METTL3 inhibits antitumor immunity by targeting m(6)a-BHLHE41-CXCL1\/CXCR2 Axis to promote colorectal cancer","volume":"163","author":"Chen","year":"2022","journal-title":"Gastroenterology"},{"issue":"1","key":"10.1016\/j.redox.2025.103647_bib34","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.ccell.2020.04.017","article-title":"Targeting FTO suppresses cancer stem cell maintenance and immune evasion","volume":"38","author":"Su","year":"2020","journal-title":"Cancer Cell"},{"issue":"1\u20132","key":"10.1016\/j.redox.2025.103647_bib35","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.cell.2017.11.031","article-title":"R-2HG exhibits anti-tumor activity by targeting FTO\/m(6)A\/MYC\/CEBPA signaling","volume":"172","author":"Su","year":"2018","journal-title":"Cell"},{"issue":"2","key":"10.1016\/j.redox.2025.103647_bib36","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.ymthe.2022.10.012","article-title":"N6-methyladenosine demethylase FTO enhances chemo-resistance in colorectal cancer through SIVA1-mediated apoptosis","volume":"31","author":"Lin","year":"2023","journal-title":"Mol. Ther."},{"issue":"33","key":"10.1016\/j.redox.2025.103647_bib37","doi-asserted-by":"crossref","first-page":"5168","DOI":"10.1038\/s41388-021-01916-0","article-title":"FTO downregulation mediated by hypoxia facilitates colorectal cancer metastasis","volume":"40","author":"Ruan","year":"2021","journal-title":"Oncogene"},{"issue":"5","key":"10.1016\/j.redox.2025.103647_bib38","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1038\/nrc3495","article-title":"Iron and cancer: more ore to be mined","volume":"13","author":"Torti","year":"2013","journal-title":"Nat. Rev. Cancer"},{"issue":"3","key":"10.1016\/j.redox.2025.103647_bib39","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.bbagen.2011.07.016","article-title":"The transferrin receptor and the targeted delivery of therapeutic agents against cancer","volume":"1820","author":"Daniels","year":"2012","journal-title":"Biochim. Biophys. Acta"},{"issue":"7","key":"10.1016\/j.redox.2025.103647_bib40","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/j.bbagen.2008.04.003","article-title":"Cancer cell iron metabolism and the development of potent iron chelators as anti-tumour agents","volume":"1790","author":"Richardson","year":"2009","journal-title":"Biochim. Biophys. Acta"},{"issue":"1","key":"10.1016\/j.redox.2025.103647_bib41","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1038\/s41569-022-00735-4","article-title":"The molecular and metabolic landscape of iron and ferroptosis in cardiovascular disease","volume":"20","author":"Fang","year":"2023","journal-title":"Nat. Rev. Cardiol."},{"issue":"12","key":"10.1016\/j.redox.2025.103647_bib42","doi-asserted-by":"crossref","first-page":"4266","DOI":"10.1080\/15548627.2021.1911016","article-title":"Ferritinophagy is involved in the zinc oxide nanoparticles-induced ferroptosis of vascular endothelial cells","volume":"17","author":"Qin","year":"2021","journal-title":"Autophagy"},{"issue":"1","key":"10.1016\/j.redox.2025.103647_bib43","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1186\/s12943-020-01220-7","article-title":"METTL14-mediated N6-methyladenosine modification of SOX4 mRNA inhibits tumor metastasis in colorectal cancer","volume":"19","author":"Chen","year":"2020","journal-title":"Mol. Cancer"},{"issue":"1\u20132","key":"10.1016\/j.redox.2025.103647_bib44","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/s10555-009-9183-x","article-title":"Emerging role of nuclear protein 1 (NUPR1) in cancer biology","volume":"28","author":"Chowdhury","year":"2009","journal-title":"Cancer Metastasis Rev."},{"issue":"6","key":"10.1016\/j.redox.2025.103647_bib45","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2016.175","article-title":"NUPR1, a new target in liver cancer: implication in controlling cell growth, migration, invasion and sorafenib resistance","volume":"7","author":"Emma","year":"2016","journal-title":"Cell Death Dis."},{"issue":"1","key":"10.1016\/j.redox.2025.103647_bib46","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1186\/s10020-025-01126-4","article-title":"FTO inhibition mitigates high-fat diet-induced metabolic disturbances and cognitive decline in SAMP8 mice","volume":"31","author":"Irisarri","year":"2025","journal-title":"Mol Med"},{"key":"10.1016\/j.redox.2025.103647_bib47","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.neuroscience.2019.08.021","article-title":"FTO: an emerging molecular player in neuropsychiatric diseases","volume":"418","author":"Annapoorna","year":"2019","journal-title":"Neuroscience"},{"issue":"3","key":"10.1016\/j.redox.2025.103647_bib48","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202002413RR","article-title":"NUPR1 protects liver from lipotoxic injury by improving the endoplasmic reticulum stress response","volume":"35","author":"Teresa Borrello","year":"2021","journal-title":"FASEB J."},{"issue":"13","key":"10.1016\/j.redox.2025.103647_bib49","doi-asserted-by":"crossref","first-page":"4081","DOI":"10.1111\/febs.15700","article-title":"NUPR1 interacts with eIF2alpha and is required for resolution of the ER stress response in pancreatic tissue","volume":"288","author":"Borrello","year":"2021","journal-title":"FEBS J."}],"container-title":["Redox Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213231725001600?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213231725001600?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T13:22:20Z","timestamp":1762608140000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213231725001600"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":49,"alternative-id":["S2213231725001600"],"URL":"https:\/\/doi.org\/10.1016\/j.redox.2025.103647","relation":{},"ISSN":["2213-2317"],"issn-type":[{"value":"2213-2317","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"FTO facilitates colorectal cancer chemoresistance via regulation of NUPR1-dependent iron homeostasis","name":"articletitle","label":"Article Title"},{"value":"Redox Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.redox.2025.103647","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"103647"}}