{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T01:25:24Z","timestamp":1792632324451,"version":"4.5.0"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T00:00:00Z","timestamp":1754352000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001677","name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001677","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["ANR-19-CE18-0029 KIRI"],"award-info":[{"award-number":["ANR-19-CE18-0029 KIRI"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010076","name":"Conseil R\u00e9gional Provence-Alpes-C\u00f4te d'Azur","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010076","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021852","name":"Centre Hospitalier Universitaire de Poitiers","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100021852","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002915","name":"Foundation for Medical Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002915","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Redox Biology"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.redox.2025.103814","type":"journal-article","created":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T08:25:43Z","timestamp":1754468743000},"page":"103814","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Inhibition of eIF5A hypusination enhances antioxidant defense to prevent kidney Ischemia\/Reperfusion injury"],"prefix":"10.1016","volume":"86","author":[{"given":"Marc","family":"Cougnon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9bastien","family":"Giraud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Materozzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa","family":"Allart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Rubera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Mackowiak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gis\u00e8le","family":"Jarretou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nad\u00e8ge","family":"Boildieu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginie","family":"Ameteau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Estelle","family":"Lemari\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajar","family":"Ouahmi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Melis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mallorie","family":"Poet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Duranton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc","family":"Pellerin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Counillon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Shkreli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Tauc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Hauet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5879-8527","authenticated-orcid":false,"given":"Didier F.","family":"Pisani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"11","key":"10.1016\/j.redox.2025.103814_bib1","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1038\/nm.2507","article-title":"Ischemia and reperfusion--from mechanism to translation","volume":"17","author":"Eltzschig","year":"2011","journal-title":"Nat. Med."},{"issue":"6","key":"10.1016\/j.redox.2025.103814_bib2","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1080\/08941930500328862","article-title":"Molecular biology of apoptosis in ischemia and reperfusion","volume":"18","author":"Lopez-Neblina","year":"2005","journal-title":"J. Invest. Surg."},{"issue":"2","key":"10.1016\/j.redox.2025.103814_bib3","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/1440-1681.12034","article-title":"Determinants of kidney oxygen consumption and their relationship to tissue oxygen tension in diabetes and hypertension","volume":"40","author":"Hansell","year":"2013","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"issue":"2","key":"10.1016\/j.redox.2025.103814_bib4","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.trsl.2007.11.001","article-title":"Heart, kidney, and intestine have different tolerances for anemia","volume":"151","author":"van Bommel","year":"2008","journal-title":"Transl. Res."},{"issue":"1","key":"10.1016\/j.redox.2025.103814_bib5","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1046\/j.1523-1755.2001.00483.x","article-title":"Nephron pO2 and renal oxygen usage in the hypertensive rat kidney","volume":"59","author":"Welch","year":"2001","journal-title":"Kidney Int."},{"issue":"4","key":"10.1016\/j.redox.2025.103814_bib6","doi-asserted-by":"crossref","first-page":"414","DOI":"10.23876\/j.krcp.19.063","article-title":"The role of oxidative stress and hypoxia in renal disease","volume":"38","author":"Honda","year":"2019","journal-title":"Kidney Res Clin Pract"},{"issue":"7","key":"10.1016\/j.redox.2025.103814_bib7","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1111\/j.1440-1681.2006.04391.x","article-title":"Renal preglomerular arterial-venous O2 shunting is a structural anti-oxidant defence mechanism of the renal cortex","volume":"33","author":"O'Connor","year":"2006","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.redox.2025.103814_bib8","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/j.redox.2015.08.020","article-title":"Reperfusion injury and reactive oxygen species: the evolution of a concept","volume":"6","author":"Granger","year":"2015","journal-title":"Redox Biol."},{"key":"10.1016\/j.redox.2025.103814_bib9","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.redox.2015.07.008","article-title":"Antioxidant responses and cellular adjustments to oxidative stress","volume":"6","author":"Espinosa-Diez","year":"2015","journal-title":"Redox Biol."},{"issue":"2","key":"10.1016\/j.redox.2025.103814_bib10","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.pharmthera.2011.11.004","article-title":"The cellular and molecular origin of reactive oxygen species generation during myocardial ischemia and reperfusion","volume":"133","author":"Raedschelders","year":"2012","journal-title":"Pharmacol. Ther."},{"issue":"6","key":"10.1016\/j.redox.2025.103814_bib11","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1080\/14728222.2019.1609451","article-title":"Emerging therapeutic strategies for transplantation-induced acute kidney injury: protecting the organelles and the vascular bed","volume":"23","author":"Melis","year":"2019","journal-title":"Expert Opin. Ther. Targets"},{"key":"10.1016\/j.redox.2025.103814_bib12","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.freeradbiomed.2021.04.023","article-title":"Targeting oxidative stress, a crucial challenge in renal transplantation outcome","volume":"169","author":"Carcy","year":"2021","journal-title":"Free Radic. Biol. Med."},{"issue":"10","key":"10.1016\/j.redox.2025.103814_bib13","doi-asserted-by":"crossref","first-page":"R453","DOI":"10.1016\/j.cub.2014.03.034","article-title":"ROS function in redox signaling and oxidative stress","volume":"24","author":"Schieber","year":"2014","journal-title":"Curr. Biol."},{"issue":"1","key":"10.1016\/j.redox.2025.103814_bib14","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1083\/jcb.200208089","article-title":"Caspase-mediated loss of mitochondrial function and generation of reactive oxygen species during apoptosis","volume":"160","author":"Ricci","year":"2003","journal-title":"J. Cell Biol."},{"issue":"5","key":"10.1016\/j.redox.2025.103814_bib15","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1038\/sj.cdd.4401225","article-title":"Mitochondrial functions during cell death, a complex (I-V) dilemma","volume":"10","author":"Ricci","year":"2003","journal-title":"Cell Death Differ."},{"issue":"Pt 2","key":"10.1016\/j.redox.2025.103814_bib16","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1113\/jphysiol.2003.049478","article-title":"Mitochondrial formation of reactive oxygen species","volume":"552","author":"Turrens","year":"2003","journal-title":"J. Physiol."},{"issue":"38","key":"10.1016\/j.redox.2025.103814_bib17","doi-asserted-by":"crossref","first-page":"36027","DOI":"10.1074\/jbc.M304854200","article-title":"Production of reactive oxygen species by mitochondria: central role of complex III","volume":"278","author":"Chen","year":"2003","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.redox.2025.103814_bib18","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.cmet.2015.12.009","article-title":"A unifying mechanism for mitochondrial superoxide production during ischemia-reperfusion injury","volume":"23","author":"Chouchani","year":"2016","journal-title":"Cell Metab."},{"issue":"41","key":"10.1016\/j.redox.2025.103814_bib19","doi-asserted-by":"crossref","first-page":"6615","DOI":"10.1021\/bi500582r","article-title":"Measurement and characterization of superoxide generation from xanthine dehydrogenase: a redox-regulated pathway of radical generation in ischemic tissues","volume":"53","author":"Lee","year":"2014","journal-title":"Biochemistry"},{"issue":"5","key":"10.1016\/j.redox.2025.103814_bib20","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.freeradbiomed.2010.04.030","article-title":"NADPH oxidases in cardiovascular disease","volume":"49","author":"Brandes","year":"2010","journal-title":"Free Radic. Biol. Med."},{"issue":"2","key":"10.1016\/j.redox.2025.103814_bib21","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.bbrc.2018.05.045","article-title":"Mini-review: oxidative stress, redox stress or redox success?","volume":"502","author":"Gutteridge","year":"2018","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.redox.2025.103814_bib22","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1146\/annurev.pharmtox.47.120505.105122","article-title":"Mitochondrial oxidative stress: implications for cell death","volume":"47","author":"Orrenius","year":"2007","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"issue":"1","key":"10.1016\/j.redox.2025.103814_bib23","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1152\/physrev.00029.2006","article-title":"Nitric oxide and peroxynitrite in health and disease","volume":"87","author":"Pacher","year":"2007","journal-title":"Physiol. Rev."},{"issue":"21","key":"10.1016\/j.redox.2025.103814_bib24","doi-asserted-by":"crossref","first-page":"11853","DOI":"10.1073\/pnas.93.21.11853","article-title":"Nitration and inactivation of manganese superoxide dismutase in chronic rejection of human renal allografts","volume":"93","author":"MacMillan-Crow","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"12","key":"10.1016\/j.redox.2025.103814_bib25","doi-asserted-by":"crossref","first-page":"3326","DOI":"10.1111\/ajt.15994","article-title":"The inhibition of eIF5A hypusination by GC7, a preconditioning protocol to prevent brain death-induced renal injuries in a preclinical porcine kidney transplantation model","volume":"20","author":"Giraud","year":"2020","journal-title":"Am. J. Transplant."},{"issue":"3","key":"10.1016\/j.redox.2025.103814_bib26","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1681\/ASN.2016010012","article-title":"Targeting eIF5A hypusination prevents anoxic cell death through mitochondrial silencing and improves kidney transplant outcome","volume":"28","author":"Melis","year":"2017","journal-title":"J. Am. Soc. Nephrol."},{"issue":"2","key":"10.1016\/j.redox.2025.103814_bib27","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.cmet.2019.05.003","article-title":"Polyamines and eIF5A hypusination modulate mitochondrial respiration and macrophage activation","volume":"30","author":"Puleston","year":"2019","journal-title":"Cell Metab."},{"issue":"8","key":"10.1016\/j.redox.2025.103814_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2022.110855","article-title":"Oxygen level regulates N-terminal translation elongation of selected proteins through deoxyhypusine hydroxylation","volume":"39","author":"Zhang","year":"2022","journal-title":"Cell Rep."},{"issue":"1","key":"10.1016\/j.redox.2025.103814_bib29","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1186\/s13578-021-00733-y","article-title":"The eukaryotic initiation factor 5A (eIF5A1), the molecule, mechanisms and recent insights into the pathophysiological roles","volume":"11","author":"Tauc","year":"2021","journal-title":"Cell Biosci."},{"key":"10.1016\/j.redox.2025.103814_bib30","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/j.redox.2015.09.039","article-title":"The balance of powers: redox regulation of fibrogenic pathways in kidney injury","volume":"6","author":"Okamura","year":"2015","journal-title":"Redox Biol."},{"issue":"1","key":"10.1016\/j.redox.2025.103814_bib31","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1002\/cbf.1351","article-title":"Inhibition of eukaryotic translation initiation factor 5A (eIF5A) hypusination impairs melanoma growth","volume":"25","author":"Jasiulionis","year":"2007","journal-title":"Cell Biochem. Funct."},{"issue":"4","key":"10.1016\/j.redox.2025.103814_bib32","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1681\/ASN.2017060650","article-title":"Endogenous IL-33 contributes to kidney ischemia-reperfusion injury as an alarmin","volume":"29","author":"Ferhat","year":"2018","journal-title":"J. Am. Soc. Nephrol."},{"issue":"4","key":"10.1016\/j.redox.2025.103814_bib33","doi-asserted-by":"crossref","first-page":"F796","DOI":"10.1152\/ajprenal.00237.2002","article-title":"CFTR null mutation altered cAMP-sensitive and swelling-activated Cl- currents in primary cultures of mouse nephron","volume":"284","author":"Barriere","year":"2003","journal-title":"Am. J. Physiol. Ren. Physiol."},{"issue":"3","key":"10.1016\/j.redox.2025.103814_bib34","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s00232-003-2014-z","article-title":"Swelling-activated chloride and potassium conductance in primary cultures of mouse proximal tubules. Implication of KCNE1 protein","volume":"193","author":"Barriere","year":"2003","journal-title":"J. Membr. Biol."},{"issue":"7","key":"10.1016\/j.redox.2025.103814_bib35","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1038\/nmeth.2019","article-title":"Fiji: an open-source platform for biological-image analysis","volume":"9","author":"Schindelin","year":"2012","journal-title":"Nat. Methods"},{"issue":"12","key":"10.1016\/j.redox.2025.103814_bib36","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1038\/s41419-019-2167-z","article-title":"LRRC8\/VRAC channels exhibit a noncanonical permeability to glutathione, which modulates epithelial-to-mesenchymal transition (EMT)","volume":"10","author":"Friard","year":"2019","journal-title":"Cell Death Dis."},{"issue":"4","key":"10.1016\/j.redox.2025.103814_bib37","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1038\/s41419-021-03577-z","article-title":"Inhibition of eIF5A hypusination reprogrammes metabolism and glucose handling in mouse kidney","volume":"12","author":"Cougnon","year":"2021","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.redox.2025.103814_bib38","doi-asserted-by":"crossref","DOI":"10.1177\/0271678X251347810","article-title":"Targeting seryl-tRNA synthetase to unlock ischemic resilience in stroke - insights from a proof-of-concept study","author":"Bourourou","year":"2025","journal-title":"J. Cerebr. Blood Flow Metabol."},{"issue":"2","key":"10.1016\/j.redox.2025.103814_bib39","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1074\/jbc.M603761200","article-title":"Specific aquaporins facilitate the diffusion of hydrogen peroxide across membranes","volume":"282","author":"Bienert","year":"2007","journal-title":"J. Biol. Chem."},{"issue":"6","key":"10.1016\/j.redox.2025.103814_bib40","doi-asserted-by":"crossref","first-page":"2218","DOI":"10.1046\/j.1523-1755.2002.00360.x","article-title":"Promising effects of ischemic preconditioning in renal transplantation","volume":"61","author":"Torras","year":"2002","journal-title":"Kidney Int."},{"issue":"4","key":"10.1016\/j.redox.2025.103814_bib41","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1046\/j.1464-410x.1999.00172.x","article-title":"Ischaemic preconditioning protects the rat kidney from reperfusion injury","volume":"84","author":"Toosy","year":"1999","journal-title":"BJU Int."},{"issue":"2","key":"10.1016\/j.redox.2025.103814_bib42","first-page":"200","article-title":"Brief small intestinal ischemia lessens renal ischemia-reperfusion injury in rats","volume":"57","author":"Song","year":"2007","journal-title":"Comp. Med."},{"issue":"3","key":"10.1016\/j.redox.2025.103814_bib43","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.devcel.2019.10.005","article-title":"Single-cell profiling reveals sex, lineage, and regional diversity in the mouse kidney","volume":"51","author":"Ransick","year":"2019","journal-title":"Dev. Cell"},{"issue":"3","key":"10.1016\/j.redox.2025.103814_bib44","doi-asserted-by":"crossref","DOI":"10.3390\/cells12030409","article-title":"Renal ischemia tolerance mediated by eIF5A hypusination inhibition is regulated by a specific modulation of the endoplasmic reticulum stress","volume":"12","author":"Melis","year":"2023","journal-title":"Cells"},{"issue":"2","key":"10.1016\/j.redox.2025.103814_bib45","first-page":"20","article-title":"Renal ischemia\/reperfusion injury; from pathophysiology to treatment","volume":"4","author":"Malek","year":"2015","journal-title":"J. Ren. Inj. Prev."},{"issue":"1","key":"10.1016\/j.redox.2025.103814_bib46","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1080\/15548627.2019.1687967","article-title":"Polyamines reverse immune senescence via the translational control of autophagy","volume":"16","author":"Zhang","year":"2020","journal-title":"Autophagy"},{"issue":"2","key":"10.1016\/j.redox.2025.103814_bib47","doi-asserted-by":"crossref","first-page":"201","DOI":"10.4161\/auto.27198","article-title":"Autophagy and SQSTM1 on the RHOA(d) again: emerging roles of autophagy in the degradation of signaling proteins","volume":"10","author":"Belaid","year":"2014","journal-title":"Autophagy"},{"key":"10.1016\/j.redox.2025.103814_bib48","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.freeradbiomed.2015.06.017","article-title":"Regulation of catalase expression in healthy and cancerous cells","volume":"87","author":"Glorieux","year":"2015","journal-title":"Free Radic. Biol. Med."},{"issue":"20","key":"10.1016\/j.redox.2025.103814_bib49","doi-asserted-by":"crossref","first-page":"13908","DOI":"10.1074\/jbc.274.20.13908","article-title":"Mechanisms of protection of catalase by NADPH. Kinetics and stoichiometry","volume":"274","author":"Kirkman","year":"1999","journal-title":"J. Biol. Chem."},{"issue":"4","key":"10.1016\/j.redox.2025.103814_bib50","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/j.cmet.2020.02.017","article-title":"Serine catabolism feeds NADH when respiration is impaired","volume":"31","author":"Yang","year":"2020","journal-title":"Cell Metab."},{"issue":"10","key":"10.1016\/j.redox.2025.103814_bib51","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1016\/j.stem.2024.07.009","article-title":"Mitochondrial serine catabolism safeguards maintenance of the hematopoietic stem cell pool in homeostasis and injury","volume":"31","author":"Du","year":"2024","journal-title":"Cell Stem Cell"},{"issue":"12","key":"10.1016\/j.redox.2025.103814_bib52","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1158\/2159-8290.CD-14-0250","article-title":"Serine catabolism regulates mitochondrial redox control during hypoxia","volume":"4","author":"Ye","year":"2014","journal-title":"Cancer Discov."},{"key":"10.1016\/j.redox.2025.103814_bib53","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s12967-016-0767-2","article-title":"Improving the outcome of kidney transplantation by ameliorating renal ischemia reperfusion injury: lost in translation?","volume":"14","author":"Saat","year":"2016","journal-title":"J. Transl. Med."},{"issue":"4","key":"10.1016\/j.redox.2025.103814_bib54","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1177\/1074248417702893","article-title":"Ischemic conditioning in kidney transplantation","volume":"22","author":"Veighey","year":"2017","journal-title":"J. Cardiovasc. Pharmacol. Therapeut."},{"issue":"8","key":"10.1016\/j.redox.2025.103814_bib55","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1034\/j.1600-6143.2002.20810.x","article-title":"Increased transplanted organs from the use of a standardized donor management protocol","volume":"2","author":"Rosendale","year":"2002","journal-title":"Am. J. Transplant."},{"issue":"3","key":"10.1016\/j.redox.2025.103814_bib56","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1097\/01.TP.0000044171.97375.61","article-title":"Multivariate analysis of donor risk factors for graft survival in kidney transplantation","volume":"75","author":"Pessione","year":"2003","journal-title":"Transplantation"}],"container-title":["Redox Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213231725003271?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213231725003271?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T14:05:31Z","timestamp":1778853931000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213231725003271"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":56,"alternative-id":["S2213231725003271"],"URL":"https:\/\/doi.org\/10.1016\/j.redox.2025.103814","relation":{},"ISSN":["2213-2317"],"issn-type":[{"value":"2213-2317","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Inhibition of eIF5A hypusination enhances antioxidant defense to prevent kidney Ischemia\/Reperfusion injury","name":"articletitle","label":"Article Title"},{"value":"Redox Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.redox.2025.103814","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"103814"}}