{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T06:39:21Z","timestamp":1765607961014,"version":"3.44.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2004,3,1]],"date-time":"2004-03-01T00:00:00Z","timestamp":1078099200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,3,1]],"date-time":"2004-03-01T00:00:00Z","timestamp":1078099200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001349","name":"National Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001349","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Regulatory Peptides"],"published-print":{"date-parts":[[2004,3]]},"DOI":"10.1016\/j.regpep.2003.10.030","type":"journal-article","created":{"date-parts":[[2003,12,12]],"date-time":"2003-12-12T11:09:13Z","timestamp":1071227353000},"page":"213-217","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Effects of des-aspartate-angiotensin I on neointima growth and cardiovascular hypertrophy"],"prefix":"10.1016","volume":"117","author":[{"given":"Sim Meng","family":"Kwoon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tang Feng","family":"Ru","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xu Xiao","family":"Guang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.regpep.2003.10.030_BIB1","doi-asserted-by":"crossref","first-page":"1524","DOI":"10.1016\/0006-2952(93)90054-Z","article-title":"Degradation of angiotensin I in the endothelium and smooth muscle of the rat aorta","volume":"45","author":"Sim","year":"1994","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.regpep.2003.10.030_BIB2","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1016\/0006-2952(94)90376-X","article-title":"Degradation of angiotensin I to [des-Asp1]angiotensin I by a novel aminopeptidase in the rat hypothalamus","volume":"48","author":"Sim","year":"1994","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.regpep.2003.10.030_BIB3","doi-asserted-by":"crossref","first-page":"R1","DOI":"10.1016\/0014-2999(94)90714-5","article-title":"Novel central action of des-Asp-angiotensin I","volume":"257","author":"Sim","year":"1994","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.regpep.2003.10.030_BIB4","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/0014-2999(95)00461-S","article-title":"Effects of des-Asp-angiotensin I on the electrically-stimulated contraction of the rabbit pulmonary artery","volume":"284","author":"Sim","year":"1995","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.regpep.2003.10.030_BIB5","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/0014-2999(95)00686-9","article-title":"Actions of d-aminoacid-substituted analogues of des-Asp-angiotensin I on the central pressor action of angiotensin III","volume":"294","author":"Radhakrishnan","year":"1995","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.regpep.2003.10.030_BIB6","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/0014-2999(95)00163-F","article-title":"Effects of des-Asp-angiotensin I on the contractile action of angiotensin II and angiotensin III","volume":"278","author":"Sim","year":"1995","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.regpep.2003.10.030_BIB7","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1111\/j.1476-5381.1996.tb15313.x","article-title":"Subtypes of losartan-sensitive angiotensin receptor in the rabbit pulmonary artery","volume":"117","author":"Sim","year":"1996","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.regpep.2003.10.030_BIB8","doi-asserted-by":"crossref","first-page":"105","DOI":"10.3109\/10641969809053210","article-title":"Actions of des-Asp-angiotensin I on the aortic rings of the normo- and hypertensive rats","volume":"20","author":"Lim","year":"1998","journal-title":"Clin. Exp. Hypertens."},{"key":"10.1016\/j.regpep.2003.10.030_BIB9","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0167-5273(97)00324-0","article-title":"Effects of des-Asp-angiotensin II on experimentally-induced cardiac hypertrophy in rats","volume":"63","author":"Sim","year":"1998","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.regpep.2003.10.030_BIB10","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0167-0115(00)00162-2","article-title":"Effects of des-aspartate-angiotensin I on angiotensin II-induced incorporation of phenylalanine and thymidine in cultured rat cardiomyocytes and aortic smooth cells","volume":"95","author":"Min","year":"2000","journal-title":"Regul. Pept."},{"key":"10.1016\/j.regpep.2003.10.030_BIB11","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0167-0115(02)00289-6","article-title":"Angiotensins in plasma of hypertensive rats and human","volume":"111","author":"Sim","year":"2003","journal-title":"Regul. Pept."},{"key":"10.1016\/j.regpep.2003.10.030_BIB12","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1161\/01.HYP.28.1.104","article-title":"Angiotensin-(1\u20137) inhibits vascular smooth muscle cell growth","volume":"28","author":"Freeman","year":"1996","journal-title":"Hypertension"},{"key":"10.1016\/j.regpep.2003.10.030_BIB13","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1590\/S0100-879X1998000900014","article-title":"Antihypertensive effects of angiotensin-(1\u20137)","volume":"31","author":"Chappell","year":"1998","journal-title":"Braz. J. Med. Biol. Res."},{"key":"10.1016\/j.regpep.2003.10.030_BIB14","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1161\/01.HYP.33.1.207","article-title":"Angiotensin-(1\u20137) reduces smooth muscle growth after vascular injury","volume":"33","author":"Strawn","year":"1999","journal-title":"Hypertension"},{"key":"10.1016\/j.regpep.2003.10.030_BIB15","series-title":"Hemostasis and thrombosis: basic principles and clinical practice","first-page":"763","article-title":"Vascular response to injury","author":"Clowes","year":"2001"},{"key":"10.1016\/j.regpep.2003.10.030_BIB16","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1161\/01.CIR.92.5.1230","article-title":"Smooth muscle cell proliferation is proportional to the degree of balloon injury in a rat model of angioplasty","volume":"92","author":"Indolfi","year":"1995","journal-title":"Circulation"},{"key":"10.1016\/j.regpep.2003.10.030_BIB17","first-page":"208","article-title":"Mechanisms of stenosis after arterial injury","volume":"49","author":"Clowes","year":"1983","journal-title":"Lab. Invest."},{"key":"10.1016\/j.regpep.2003.10.030_BIB18","first-page":"611","article-title":"Kinetics of cellular proliferation after arterial injury: II. Inhibition of smooth muscle growth by heparin","volume":"52","author":"Clowes","year":"1985","journal-title":"Lab. Invest."},{"issue":"Suppl. II","key":"10.1016\/j.regpep.2003.10.030_BIB19","first-page":"II-60","article-title":"Role of angiotensin II in injury-induced neointima formation in rats","volume":"18","author":"Osterrieder","year":"1991","journal-title":"Hypertension"},{"key":"10.1016\/j.regpep.2003.10.030_BIB20","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1161\/01.RES.68.2.450","article-title":"Angiotensin II induces smooth muscle cell proliferation in the normal and injured rat arterial wall","volume":"68","author":"Daemen","year":"1991","journal-title":"Circ. Res."},{"key":"10.1016\/j.regpep.2003.10.030_BIB21","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1016\/0006-291X(92)90473-X","article-title":"Neointima formation after vascular injury is angiotensin II mediated","volume":"187","author":"Laporte","year":"1992","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.regpep.2003.10.030_BIB22","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1097\/00005344-199322005-00002","article-title":"Vascular renin\u2013angiotensin system and vascular projection","volume":"22","author":"Dzau","year":"1993","journal-title":"J. Cardiovasc. Pharmacol."},{"key":"10.1016\/j.regpep.2003.10.030_BIB23","doi-asserted-by":"crossref","first-page":"137B","DOI":"10.1016\/0735-1097(91)90950-E","article-title":"Suppression of the vascular response to injury: the role of angiotensin-converting enzyme inhibitors","volume":"17","author":"Powel","year":"1991","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.regpep.2003.10.030_BIB24","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1161\/01.CIR.85.4.1542","article-title":"Cilazapril and early atherosclerotic changes after balloon injury of porcine carotid arteries","volume":"85","author":"Lam","year":"1992","journal-title":"Circulation"},{"key":"10.1016\/j.regpep.2003.10.030_BIB25","first-page":"573","article-title":"Effect of cilazapril on vascular restenosis after percutaneous transluminal coronary angioplasty","volume":"6","author":"Yamabe","year":"1995","journal-title":"Coron. Artery Dis."},{"key":"10.1016\/j.regpep.2003.10.030_BIB26","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1161\/01.CIR.86.1.100","article-title":"Does the new angiotensin converting inhibitor cilazapril prevent restenosis after percutaneous transluminal coronary angioplasty? Result of the MERCATOR study: a multicenter, randomized double-blind placebo-controlled trial","volume":"86","year":"1992","journal-title":"Circulation"},{"key":"10.1016\/j.regpep.2003.10.030_BIB27","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/0735-1097(94)00368-Z","article-title":"Effect of high dose angiotensin-converting enzyme inhibition on restenosis: final results of the MARCTOR Study, a multicenter, double-blind, placebo-controlled trial of cilazapril","volume":"25","author":"Faxon","year":"1995","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.regpep.2003.10.030_BIB28","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/S0002-9149(02)02242-7","article-title":"Evidence that angiotensin-converting enzyme inhibitor use diminishes the need for coronary revascularization after stenting","volume":"89","author":"Ellis","year":"2002","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.regpep.2003.10.030_BIB29","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1253\/circj.66.311","article-title":"Quinapril prevents restenosis after coronary stenting in patient with angiotensin-converting enzyme D allele","volume":"66","author":"Okumura","year":"2002","journal-title":"Circ. J."},{"key":"10.1016\/j.regpep.2003.10.030_BIB30","first-page":"149","article-title":"Update on pharmacology of restenosis","volume":"3","author":"Chan","year":"2001","journal-title":"Curr. Interv. Cardiol. Rep."},{"key":"10.1016\/j.regpep.2003.10.030_BIB31","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1161\/01.RES.62.4.749","article-title":"Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells","volume":"62","author":"Geisterfer","year":"1988","journal-title":"Circ. Res."},{"key":"10.1016\/j.regpep.2003.10.030_BIB32","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1161\/01.RES.80.5.607","article-title":"Angiotensin II signal transduction in vascular smooth muscle: role of tyrosine kinase","volume":"80","author":"Berk","year":"1997","journal-title":"Circ. Res."},{"key":"10.1016\/j.regpep.2003.10.030_BIB33","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1172\/JCI118807","article-title":"Chronic blockade of AT2-subtype receptors prevents the effect of angiotensin II on the rat vascular structure","volume":"98","author":"Levy","year":"1996","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.regpep.2003.10.030_BIB34","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1097\/00004872-200108000-00007","article-title":"Persistent cardiovascular effects of chronic renin\u2013angiotensin system inhibition following withdrawal in adult spontaneously hypertensive rats","volume":"19","author":"Paull","year":"2001","journal-title":"J. Hypertens."},{"key":"10.1016\/j.regpep.2003.10.030_BIB35","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1023\/A:1005646614308","article-title":"The effects of anti-hypertensive therapy on the structural, mechanical and metabolic properties of the rat aorta","volume":"21","author":"Clark","year":"2000","journal-title":"J. Muscle Res. Cell Motil."},{"key":"10.1016\/j.regpep.2003.10.030_BIB36","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/0014-2999(95)00686-9","article-title":"Actions of d-amino acid-substituted analogues of des-Asp-angiotensin I on the central pressor action of angiotensin III","volume":"295","author":"Radhakrishnan","year":"1995","journal-title":"Eur. J. Pharmacol."}],"container-title":["Regulatory Peptides"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016701150300243X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016701150300243X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T15:15:52Z","timestamp":1759072552000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016701150300243X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,3]]},"references-count":36,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2004,3]]}},"alternative-id":["S016701150300243X"],"URL":"https:\/\/doi.org\/10.1016\/j.regpep.2003.10.030","relation":{},"ISSN":["0167-0115"],"issn-type":[{"type":"print","value":"0167-0115"}],"subject":[],"published":{"date-parts":[[2004,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of des-aspartate-angiotensin I on neointima growth and cardiovascular hypertrophy","name":"articletitle","label":"Article Title"},{"value":"Regulatory Peptides","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.regpep.2003.10.030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2003 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}