{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T17:39:39Z","timestamp":1760204379726,"version":"3.44.0"},"reference-count":47,"publisher":"Elsevier BV","issue":"1-3","license":[{"start":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T00:00:00Z","timestamp":1254355200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T00:00:00Z","timestamp":1254355200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2010,7,10]],"date-time":"2010-07-10T00:00:00Z","timestamp":1278720000000},"content-version":"vor","delay-in-days":282,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Regulatory Peptides"],"published-print":{"date-parts":[[2009,10]]},"DOI":"10.1016\/j.regpep.2009.07.002","type":"journal-article","created":{"date-parts":[[2009,7,11]],"date-time":"2009-07-11T04:33:51Z","timestamp":1247286831000},"page":"14-18","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Involvement of the intermediate nucleus of the lateral septal area on angiotensin II-induced dipsogenic and pressor responses"],"prefix":"10.1016","volume":"157","author":[{"given":"Andre H.","family":"Freiria-Oliveira","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graziela T.","family":"Blanch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis A.A.","family":"Camargo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 V.","family":"Menani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wilson A.","family":"Saad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.regpep.2009.07.002_bib1","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1113\/jphysiol.1963.sp007154","article-title":"The effects of slow infusions of hypertonic solutions on drinking and drinking thresholds in rats","volume":"167","author":"Fitzsimons","year":"1963","journal-title":"J Physiol"},{"key":"10.1016\/j.regpep.2009.07.002_bib2","first-page":"119","article-title":"Fisiologia del area septal","volume":"16","author":"Covian","year":"1966","journal-title":"Acta Physiol Latinoam"},{"issue":"1","key":"10.1016\/j.regpep.2009.07.002_bib3","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1113\/jphysiol.1969.sp008848","article-title":"The effect on drinking in the rat of intravenous infusion of angiotensin, given alone or in combination with other stimuli of thirst","volume":"203","author":"Fitzsimons","year":"1969","journal-title":"J Physiol"},{"issue":"2","key":"10.1016\/j.regpep.2009.07.002_bib4","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1113\/jphysiol.1970.sp009220","article-title":"Drinking induced by injection of angiotensin into the rain of the rat","volume":"210","author":"Epstein","year":"1970","journal-title":"J Physiol"},{"key":"10.1016\/j.regpep.2009.07.002_bib5","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0031-9384(72)90162-X","article-title":"Water and sodium chloride intake following microinjection of angiotensin II into the septal area of the rat brain","volume":"9","author":"Covian","year":"1972","journal-title":"Physiol Behav"},{"issue":"2","key":"10.1016\/j.regpep.2009.07.002_bib6","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1113\/jphysiol.1975.sp011204","article-title":"Some central mechanisms of thirst in the dog","volume":"253","author":"Ramsay","year":"1975","journal-title":"J Physiol"},{"issue":"3","key":"10.1016\/j.regpep.2009.07.002_bib7","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1152\/physrev.1978.58.3.582","article-title":"Regulation of water intake","volume":"58","author":"Andersson","year":"1978","journal-title":"Physiol Rev"},{"key":"10.1016\/j.regpep.2009.07.002_bib8","first-page":"R333","article-title":"Thirst and vasopressin release in the dog: an osmoreceptor or sodium receptor mechanism?","volume":"238","author":"Thrasher","year":"1980","journal-title":"Am J Physiol"},{"issue":"33","key":"10.1016\/j.regpep.2009.07.002_bib9","doi-asserted-by":"crossref","first-page":"R211","DOI":"10.1152\/ajpregu.1993.264.1.R211","article-title":"Effects of arterial pressure on drinking and urinary responses to intracerebroventricular angiotensin II","volume":"264","author":"Thunhorst","year":"1993","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"3","key":"10.1016\/j.regpep.2009.07.002_bib10","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1152\/physrev.1998.78.3.583","article-title":"Angiotensin, thirst, and sodium appetite","volume":"78","author":"Fitzsimons","year":"1998","journal-title":"Physiol Rev"},{"key":"10.1016\/j.regpep.2009.07.002_bib11","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1590\/S0100-879X1998001200013","article-title":"Role of angiotensin II and vasopressin receptors within the supraoptic nucleus in water and sodium intake induced by the injection of angiotensin II into the medial septal area","volume":"31","author":"Antunes","year":"1998","journal-title":"Braz J Med Biol Res"},{"issue":"6","key":"10.1016\/j.regpep.2009.07.002_bib12","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/S0361-9230(01)00469-5","article-title":"Role of the alpha1 and alpha2 adrenoceptors of the paraventricular nucleus on the water and salt intake, renal excretion, and arterial pressure induced by angiotensin II injection into the medial septal area","volume":"54","author":"Camargo","year":"2001","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.regpep.2009.07.002_bib13","first-page":"369","article-title":"Integration between the lateral preoptic area and subfornical organ in the regulation of water intake and hemodynamics in the rat","volume":"20","author":"Saad","year":"1987","journal-title":"Braz J Med Biol Res"},{"key":"10.1016\/j.regpep.2009.07.002_bib14","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/0361-9230(94)90191-0","article-title":"Role of the medial septal area on the cardiovascular, fluid and electrolytic responses to angiotensin II and cholinergic activation into the subfornical organ in rats","volume":"33","author":"Colombari","year":"1994","journal-title":"Brain Res Bull"},{"issue":"5","key":"10.1016\/j.regpep.2009.07.002_bib15","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/0361-9230(95)00025-A","article-title":"Role of cholinergic and adrenergic pathways of the medial septal area in the water intake and pressor response to central angiotensin II and carbachol in rats","volume":"37","author":"Barbosa","year":"1995","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.regpep.2009.07.002_bib16","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/j.pbb.2004.01.013","article-title":"Interaction between supraoptic nucleus and septal area in the control of water, sodium intake and arterial blood pressure induced by injection of angiotensin II","volume":"77","author":"Saad","year":"2004","journal-title":"Pharmacol Biochem Behav"},{"issue":"105","key":"10.1016\/j.regpep.2009.07.002_bib17","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1126\/science.181.4105.1172","article-title":"Subfornical organ: site of drinking elicitation by angiotensin II","volume":"181","author":"Simpson","year":"1973","journal-title":"Science"},{"issue":"8","key":"10.1016\/j.regpep.2009.07.002_bib18","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1523\/JNEUROSCI.02-08-01043.1982","article-title":"Subfornical organ-median preoptic connections and drinking and pressor responses to angiotensin II","volume":"2","author":"Lind","year":"1982","journal-title":"J Neurosci"},{"issue":"2 Pt 2","key":"10.1016\/j.regpep.2009.07.002_bib19","first-page":"R374","article-title":"Rat organum vasculosum laminae terminalis in vitro: responses to transmitters","volume":"247","author":"Sayer","year":"1984","journal-title":"Am J Physiol"},{"issue":"1","key":"10.1016\/j.regpep.2009.07.002_bib20","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/0006-8993(91)90760-S","article-title":"Intravenous hypertonic saline induces Fos immunoreactivity in neurons throughout the lamina terminalis","volume":"561","author":"Oldfield","year":"1991","journal-title":"Brain Res"},{"issue":"3","key":"10.1016\/j.regpep.2009.07.002_bib21","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1006\/frne.1994.1010","article-title":"Osmoreceptors, osmoreception, and osmoregulation","volume":"15","author":"Bourque","year":"1994","journal-title":"Front Neuroendocrinol"},{"key":"10.1016\/j.regpep.2009.07.002_bib22","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/S0163-1047(80)91471-5","article-title":"Interaction between the lateral preoptic area and the subfornical organ in the control of water ingestion caused by cellular dehydration, hypotension, hypovolemia, and deprivation","volume":"28","author":"Saad","year":"1980","journal-title":"Behav Neural Biol"},{"issue":"2","key":"10.1016\/j.regpep.2009.07.002_bib23","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/0304-3940(91)90300-I","article-title":"Pressor, dipsogenic, natriuretic and kaliuretic responses to central carbachol in rats with lesion of the medial septal area","volume":"132","author":"Luiz","year":"1991","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.regpep.2009.07.002_bib24","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/0031-9384(80)90081-5","article-title":"Interaction between the septal area and the subfornical organ in the control of water intake induced by thirst-eliciting procedures","volume":"24","author":"Morita","year":"1978","journal-title":"Physiol Behav"},{"key":"10.1016\/j.regpep.2009.07.002_bib25","first-page":"49","article-title":"Role of the septal area in feeding behavior elicited by electrical stimulation of the lateral hypothalamus of the rat","volume":"23","author":"Oliveira","year":"1990","journal-title":"Braz J Med Biol Res"},{"key":"10.1016\/j.regpep.2009.07.002_bib26","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/0165-1838(94)00176-K","article-title":"Effect of lateral hypothalamus lesions on the water and salt intake, and sodium and urine excretion induced by activation of the median preoptic nucleus in conscious rats","volume":"53","author":"Silva","year":"1995","journal-title":"J Auton Nerv Syst"},{"issue":"12","key":"10.1016\/j.regpep.2009.07.002_bib27","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1046\/j.1440-1681.2001.03592.x","article-title":"Neural pathways from the lamina terminalis influencing cardiovascular and body fluid homeostasis","volume":"28","author":"McKinley","year":"2001","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"10.1016\/j.regpep.2009.07.002_bib28","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/0091-3057(74)90026-4","article-title":"Antagonism of the dipsogenic action of intraseptal angiotensin II in the rat","volume":"2","author":"Peres","year":"1974","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.regpep.2009.07.002_bib29","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1113\/jphysiol.1976.sp011529","article-title":"Identification of pathways mediating cardiovascular responses elicited by stimulation of the septum in the rat","volume":"260","author":"Calaresu","year":"1976","journal-title":"J Physiol"},{"issue":"2","key":"10.1016\/j.regpep.2009.07.002_bib30","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S0361-9230(98)00057-4","article-title":"Effect of electrolytic and chemical lesion by ibotenic acid of the septal area on water and salt intake","volume":"47","author":"Saad","year":"1998","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.regpep.2009.07.002_bib31","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/S0361-9230(03)00187-4","article-title":"Projections from the caudal part to the rostral part of lateral septal area mediate blood pressure increase","volume":"61","author":"Kanaya","year":"2003","journal-title":"Brain Res Bull"},{"issue":"5","key":"10.1016\/j.regpep.2009.07.002_bib32","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/S0361-9230(02)00928-0","article-title":"Cholinergic mechanism in the lateral septal area is involved in the stress-induced blood pressure increase in rats","volume":"59","author":"Kubo","year":"2003","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.regpep.2009.07.002_bib33","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/0031-9384(67)90029-7","article-title":"Alterations in sodium chloride and water intake after septal lesions in the rat","volume":"2","author":"Negro-Vilar","year":"1967","journal-title":"Physiol Behav"},{"issue":"1","key":"10.1016\/j.regpep.2009.07.002_bib34","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1037\/h0028385","article-title":"Primary hyperdipsia in the rat following septal lesions","volume":"70","author":"Blass","year":"1970","journal-title":"J Comp Physiol Psychol"},{"issue":"3","key":"10.1016\/j.regpep.2009.07.002_bib35","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1037\/h0036965","article-title":"Septal hyperdipsia: specific enhancement of drinking to angiotensin in rats","volume":"87","author":"Blass","year":"1974","journal-title":"J Comp Physiol Psychol"},{"key":"10.1016\/j.regpep.2009.07.002_bib36","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1159\/000123167","article-title":"The circumventricular organs and the central actions of angiotensin","volume":"32","author":"Simpson","year":"1981","journal-title":"Neuroendocrinology"},{"year":"1986","series-title":"The rat brain in stereotaxic coordinates","author":"Paxinos","key":"10.1016\/j.regpep.2009.07.002_bib37"},{"issue":"3","key":"10.1016\/j.regpep.2009.07.002_bib38","doi-asserted-by":"crossref","first-page":"R152","DOI":"10.1152\/ajpregu.1981.241.3.R152","article-title":"Isoproterenol-induced thirst: renal and extrarenal mechanisms","volume":"241","author":"Rettig","year":"1981","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"4\u20135","key":"10.1016\/j.regpep.2009.07.002_bib39","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/S0031-9384(02)00778-3","article-title":"Isotonic NaCl intake by cell-dehydrated rats","volume":"76","author":"Pereira","year":"2002","journal-title":"Physiol Behav"},{"key":"10.1016\/j.regpep.2009.07.002_bib40","series-title":"Thirst: physiology and psychological aspects","first-page":"77","article-title":"Osmoreceptors for thirst","author":"McKinley","year":"1991"},{"issue":"5","key":"10.1016\/j.regpep.2009.07.002_bib41","doi-asserted-by":"crossref","first-page":"R1085","DOI":"10.1152\/ajpregu.1995.269.5.R1085","article-title":"Drinking after intragastric NaCl without increase in systemic plasma osmolality in rats","volume":"269","author":"Kraly","year":"1995","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.regpep.2009.07.002_bib42","doi-asserted-by":"crossref","first-page":"R1710","DOI":"10.1152\/ajpregu.00548.2001","article-title":"Early osmoregulatory stimulation of neurohypophyseal hormone secretion and thirst after gastric NaCl loads","volume":"282","author":"Stricker","year":"2002","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.regpep.2009.07.002_bib43","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/0006-8993(92)90466-M","article-title":"AV3V lesion suppresses the pressor, dipsogenic and natriuretic responses to cholinergic activation of the septal area in rats","volume":"572","author":"Colombari","year":"1992","journal-title":"Brain Res"},{"key":"10.1016\/j.regpep.2009.07.002_bib44","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0361-9230(03)00186-2","article-title":"Activation of cholinergic pathways from the septum to the subfornical organ under hypovolemic condition in rat","volume":"61","author":"Tanaka","year":"2003","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.regpep.2009.07.002_bib45","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/0304-3940(79)90080-6","article-title":"Direct septo-hypothalamic projections in the rat","volume":"13","author":"Garris","year":"1979","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.regpep.2009.07.002_bib46","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1002\/cne.901860408","article-title":"The connections of the septal region in the rat","volume":"186","author":"Swanson","year":"1979","journal-title":"J Comp Neurol"},{"issue":"2 Pt 2","key":"10.1016\/j.regpep.2009.07.002_bib47","first-page":"R496","article-title":"Role of lateral hypothalamus on fluid, electrolyte, and cardiovascular responses to activation of the MSA","volume":"266","author":"Haibara","year":"1994","journal-title":"Am J Physiol"}],"container-title":["Regulatory Peptides"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167011509001517?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167011509001517?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T15:16:46Z","timestamp":1759072606000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167011509001517"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10]]},"references-count":47,"journal-issue":{"issue":"1-3","published-print":{"date-parts":[[2009,10]]}},"alternative-id":["S0167011509001517"],"URL":"https:\/\/doi.org\/10.1016\/j.regpep.2009.07.002","relation":{},"ISSN":["0167-0115"],"issn-type":[{"type":"print","value":"0167-0115"}],"subject":[],"published":{"date-parts":[[2009,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Involvement of the intermediate nucleus of the lateral septal area on angiotensin II-induced dipsogenic and pressor responses","name":"articletitle","label":"Article Title"},{"value":"Regulatory Peptides","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.regpep.2009.07.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}