{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T17:51:37Z","timestamp":1787161897134,"version":"build-2736575974"},"reference-count":47,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Neuroscience Research Center of Kerman, Iran"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Regulatory Peptides"],"published-print":{"date-parts":[[2014,11]]},"DOI":"10.1016\/j.regpep.2014.11.004","type":"journal-article","created":{"date-parts":[[2014,11,20]],"date-time":"2014-11-20T17:52:43Z","timestamp":1416505963000},"page":"11-15","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":33,"special_numbering":"C","title":["Prior regular exercise reverses the decreased effects of sleep deprivation on brain-derived neurotrophic factor levels in the hippocampus of ovariectomized female rats"],"prefix":"10.1016","volume":"194-195","author":[{"given":"Hakimeh","family":"Saadati","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vahid","family":"Sheibani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saeed","family":"Esmaeili-Mahani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatemeh","family":"Darvishzadeh-Mahani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahrzad","family":"Mazhari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.regpep.2014.11.004_bb0005","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1038\/nrn2762","article-title":"The memory function of sleep","volume":"11","author":"Diekelmann","year":"2010","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.regpep.2014.11.004_bb0010","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.brainres.2004.05.032","article-title":"Sleep deprivation impairs spatial memory and decreases extracellular signal-regulated kinase phosphorylation in the hippocampus","volume":"1018","author":"Guan","year":"2004","journal-title":"Brain Res"},{"key":"10.1016\/j.regpep.2014.11.004_bb0015","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1016\/j.mcn.2011.02.006","article-title":"Sleep deprivation prevents stimulation-induced increases of levels of P-CREB and BDNF: protection by caffeine","volume":"46","author":"Alhaider","year":"2011","journal-title":"Mol Cell Neurosci"},{"key":"10.1016\/j.regpep.2014.11.004_bb0020","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0166-2236(02)02143-4","article-title":"Exercise. a behavioral intervention to enhance brain health and plasticity","volume":"25","author":"Cotman","year":"2002","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.regpep.2014.11.004_bb0025","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.sleep.2006.02.004","article-title":"Sleep deprivation and hormone therapy in postmenopausal women","volume":"7","author":"Kalleinen","year":"2006","journal-title":"Sleep Med"},{"key":"10.1016\/j.regpep.2014.11.004_bb0030","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1097\/gme.0b013e3180321a22","article-title":"Sleep disturbance in menopause","volume":"14","author":"Freedman","year":"2007","journal-title":"Menopause"},{"key":"10.1016\/j.regpep.2014.11.004_bb0035","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1056\/NEJM200107053450106","article-title":"Postmenopausal hormone-replacement therapy","volume":"345","author":"Manson","year":"2001","journal-title":"N Engl J Med"},{"issue":"Suppl. 4","key":"10.1016\/j.regpep.2014.11.004_bb0040","first-page":"53S","article-title":"Exercise in the menopausal woman","volume":"75","author":"Shangold","year":"1990","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.regpep.2014.11.004_bb0045","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.neuroscience.2006.02.084","article-title":"Insulin-like growth factor I interfaces with brain-derived neurotrophic factor-mediated synaptic plasticity to modulate aspects of exercise-induced cognitive function","volume":"140","author":"Ding","year":"2006","journal-title":"Neuroscience"},{"key":"10.1016\/j.regpep.2014.11.004_bb0050","doi-asserted-by":"crossref","first-page":"2580","DOI":"10.1111\/j.1460-9568.2004.03720.x","article-title":"Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition","volume":"20","author":"Vaynman","year":"2004","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.regpep.2014.11.004_bb0055","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.jpsychires.2014.06.018","article-title":"Electroconvulsive therapy and aerobic exercise training increased BDNF and ameliorated depressive symptoms in patients suffering from treatment-resistant major depressive disorder","volume":"57","author":"Salehi","year":"2014","journal-title":"J Psychiatr Res"},{"key":"10.1016\/j.regpep.2014.11.004_bb0060","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1002\/hipo.20631","article-title":"Exercise enhances hippocampal\u2010dependent learning in the rat: evidence for a BDNF\u2010related mechanism","volume":"19","author":"Griffin","year":"2009","journal-title":"Hippocampus"},{"key":"10.1016\/j.regpep.2014.11.004_bb0065","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1002\/dneu.22009","article-title":"Running throughout middle\u2010age improves memory function, hippocampal neurogenesis, and BDNF levels in female C57BL\/6J mice","volume":"72","author":"Marlatt","year":"2012","journal-title":"Dev Neurobiol"},{"key":"10.1016\/j.regpep.2014.11.004_bb0070","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.tins.2004.12.005","article-title":"Similarities between actions of estrogen and BDNF in the hippocampus: coincidence or clue?","volume":"28","author":"Scharfman","year":"2005","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.regpep.2014.11.004_bb0075","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1006\/exnr.2000.7492","article-title":"BDNF protects against spatial memory deficits following neonatal hypoxia-ischemia","volume":"166","author":"Almli","year":"2000","journal-title":"Exp Neurol"},{"key":"10.1016\/j.regpep.2014.11.004_bb0080","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1038\/nm.1912","article-title":"Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease","volume":"15","author":"Nagahara","year":"2009","journal-title":"Nat Med"},{"key":"10.1016\/j.regpep.2014.11.004_bb0085","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1016\/j.nbd.2011.12.039","article-title":"The beneficial effects of regular exercise on cognition in REM sleep deprivation: behavioral, electrophysiological and molecular evidence","volume":"45","author":"Zagaar","year":"2012","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.regpep.2014.11.004_bb0090","doi-asserted-by":"crossref","first-page":"13594","DOI":"10.1073\/pnas.0901402106","article-title":"Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease","volume":"106","author":"Blurton-Jones","year":"2009","journal-title":"Proc Natl Acad Sci"},{"key":"10.1016\/j.regpep.2014.11.004_bb0095","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.brainresrev.2008.07.007","article-title":"New insights into brain BDNF function in normal aging and Alzheimer disease","volume":"59","author":"Tapia-Arancibia","year":"2008","journal-title":"Brain Res Rev"},{"key":"10.1016\/j.regpep.2014.11.004_bb0100","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.mcn.2013.07.011","article-title":"Regular treadmill exercise prevents sleep deprivation-induced disruption of synaptic plasticity and associated signaling cascade in the dentate gyrus","volume":"56","author":"Zagaar","year":"2013","journal-title":"Mol Cell Neurosci"},{"key":"10.1016\/j.regpep.2014.11.004_bb0105","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.bbr.2011.12.008","article-title":"Female rats are more susceptible to the deleterious effects of paradoxical sleep deprivation on cognitive performance","volume":"228","author":"Hajali","year":"2012","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.regpep.2014.11.004_bb0110","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.nlm.2010.07.003","article-title":"Running exercise effects on spatial and avoidance tasks in ovariectomized rats","volume":"94","author":"Ben","year":"2010","journal-title":"Neurobiol Learn Mem"},{"key":"10.1016\/j.regpep.2014.11.004_bb0115","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.pbb.2013.02.005","article-title":"Exercise-induced morphine insensitivity is accompanied with a decrease in specific G-protein subunits gene expression in rats","volume":"105","author":"Esmaeili-Mahani","year":"2013","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.regpep.2014.11.004_bb0120","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.npep.2010.02.004","article-title":"Changes in the gene expression of specific G-protein subunits correlate with morphine insensitivity in streptozotocin-induced diabetic rats","volume":"44","author":"Hajializadeh","year":"2010","journal-title":"Neuropeptides"},{"key":"10.1016\/j.regpep.2014.11.004_bb0125","series-title":"Short protocols in molecular biology: a compendium of methods from current protocols in molecular biology","volume":"vol. 2","author":"Ausubel","year":"2002"},{"key":"10.1016\/j.regpep.2014.11.004_bb0130","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.brainresbull.2014.09.009","article-title":"Prior regular exercise prevents synaptic plasticity impairment in sleep deprived female rats","volume":"108","author":"Saadati","year":"2014","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.regpep.2014.11.004_bb0135","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.neuroscience.2008.01.072","article-title":"Rapid eye movement sleep deprivation decreases long-term potentiation stability and affects some glutamatergic signaling proteins during hippocampal development","volume":"153","author":"Lopez","year":"2008","journal-title":"Neuroscience"},{"key":"10.1016\/j.regpep.2014.11.004_bb0140","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1093\/sleep\/32.2.227","article-title":"Paradoxical (REM) sleep deprivation causes a large and rapidly reversible decrease in long-term potentiation, synaptic transmission, glutamate receptor protein levels, and ERK\/MAPK activation in the dorsal hippocampus","volume":"32","author":"Ravassard","year":"2009","journal-title":"Sleep"},{"key":"10.1016\/j.regpep.2014.11.004_bb0145","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.bbr.2013.04.038","article-title":"Influence of chronic moderate sleep restriction and exercise training on anxiety, spatial memory, and associated neurobiological measures in mice","volume":"250","author":"Zielinski","year":"2013","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.regpep.2014.11.004_bb0150","doi-asserted-by":"crossref","first-page":"e76050","DOI":"10.1371\/journal.pone.0076050","article-title":"The interplay of stress and sleep impacts BDNF level","volume":"8","author":"Giese","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1016\/j.regpep.2014.11.004_bb0155","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1038\/nrn1909","article-title":"Why sex matters for neuroscience","volume":"7","author":"Cahill","year":"2006","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.regpep.2014.11.004_bb0160","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/S0165-0173(01)00136-9","article-title":"Estradiol is a protective factor in the adult and aging brain: understanding of mechanisms derived from in vivo and in vitro studies","volume":"37","author":"Wise","year":"2001","journal-title":"Brain Res Rev"},{"key":"10.1016\/j.regpep.2014.11.004_bb0165","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1001\/jama.285.11.1489","article-title":"Hormone replacement therapy and cognition: systematic review and meta-analysis","volume":"285","author":"LeBlanc","year":"2001","journal-title":"JAMA"},{"key":"10.1016\/j.regpep.2014.11.004_bb0170","doi-asserted-by":"crossref","first-page":"2123","DOI":"10.1001\/jama.288.17.2123","article-title":"Hormone replacement therapy and incidence of Alzheimer disease in older women: the Cache County Study","volume":"288","author":"Zandi","year":"2002","journal-title":"JAMA"},{"key":"10.1016\/j.regpep.2014.11.004_bb0175","first-page":"540","article-title":"Sex, steroids, and sleep: a review","volume":"22","author":"Manber","year":"1999","journal-title":"Sleep"},{"key":"10.1016\/j.regpep.2014.11.004_bb0180","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.jpsychires.2004.05.008","article-title":"Women's sleep in health and disease","volume":"39","author":"Dzaja","year":"2005","journal-title":"J Psychiatr Res"},{"key":"10.1016\/j.regpep.2014.11.004_bb0185","first-page":"1","article-title":"Among a sample of Iranian pre-menopausal and menopausal women differences in mood, sleep and health quality are small","author":"Jahangard","year":"2013","journal-title":"Int J Psychiatry Clin Pract"},{"issue":"1","key":"10.1016\/j.regpep.2014.11.004_bb0190","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.brainres.2004.01.019","article-title":"Sleep deprivation induced by the modified multiple platform technique: quantification of sleep loss and recovery","volume":"1004","author":"Machado","year":"2004","journal-title":"Brain Res"},{"key":"10.1016\/j.regpep.2014.11.004_bb0195","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0031-9384(99)00181-X","article-title":"Social stability attenuates the stress in the modified multiple platform method for paradoxical sleep deprivation in the rat","volume":"68","author":"Suchecki","year":"2000","journal-title":"Physiol Behav"},{"issue":"4","key":"10.1016\/j.regpep.2014.11.004_bb0200","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1093\/sleep\/33.4.437","article-title":"Chronic caffeine treatment prevents sleep deprivation-induced impairment of cognitive function and synaptic plasticity","volume":"33","author":"Alhaider","year":"2010","journal-title":"Sleep"},{"key":"10.1016\/j.regpep.2014.11.004_bb0205","doi-asserted-by":"crossref","first-page":"751","DOI":"10.5665\/sleep.2642","article-title":"Regular exercise prevents sleep deprivation associated impairment of long-term memory and synaptic plasticity in the CA1 area of the hippocampus","volume":"36","author":"Zagaar","year":"2012","journal-title":"Sleep"},{"key":"10.1016\/j.regpep.2014.11.004_bb0210","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.tins.2004.08.001","article-title":"BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders","volume":"27","author":"Mattson","year":"2004","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.regpep.2014.11.004_bb0215","doi-asserted-by":"crossref","first-page":"1992","DOI":"10.1046\/j.0953-816x.2001.01825.x","article-title":"Estrogen and exercise interact to regulate brain\u2010derived neurotrophic factor mRNA and protein expression in the hippocampus","volume":"14","author":"Berchtold","year":"2002","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.regpep.2014.11.004_bb0220","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.neuroscience.2011.03.050","article-title":"Voluntary exercise does not enhance long-term potentiation in the adolescent female dentate gyrus","volume":"183","author":"Titterness","year":"2011","journal-title":"Neuroscience"},{"key":"10.1016\/j.regpep.2014.11.004_bb0225","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1101\/lm.51202","article-title":"From acquisition to consolidation: on the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning","volume":"9","author":"Tyler","year":"2002","journal-title":"Learn Mem"},{"key":"10.1016\/j.regpep.2014.11.004_bb0230","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.bbr.2013.11.015","article-title":"BDNF-stimulated intracellular signalling mechanisms underlie exercise-induced improvement in spatial memory in the male Wistar rat","volume":"275","author":"Bechara","year":"2014","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.regpep.2014.11.004_bb0235","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/BF02815003","article-title":"The effects of intrahippocampal BDNF and NGF on spatial learning in aged Long Evans rats","volume":"29","author":"Pelleymounter","year":"1996","journal-title":"Mol Chem Neuropathol"}],"container-title":["Regulatory Peptides"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167011514000871?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167011514000871?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,17]],"date-time":"2019-08-17T12:38:40Z","timestamp":1566045520000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167011514000871"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11]]},"references-count":47,"alternative-id":["S0167011514000871"],"URL":"https:\/\/doi.org\/10.1016\/j.regpep.2014.11.004","relation":{},"ISSN":["0167-0115"],"issn-type":[{"value":"0167-0115","type":"print"}],"subject":[],"published":{"date-parts":[[2014,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prior regular exercise reverses the decreased effects of sleep deprivation on brain-derived neurotrophic factor levels in the hippocampus of ovariectomized female rats","name":"articletitle","label":"Article Title"},{"value":"Regulatory Peptides","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.regpep.2014.11.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}