{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T14:56:26Z","timestamp":1648738586719},"reference-count":28,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Revista Espa\u00f1ola de Medicina Nuclear e Imagen Molecular"],"published-print":{"date-parts":[[2017,1]]},"DOI":"10.1016\/j.remn.2016.05.009","type":"journal-article","created":{"date-parts":[[2016,7,15]],"date-time":"2016-07-15T18:21:33Z","timestamp":1468606893000},"page":"7-12","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["La estimulaci\u00f3n previa con rhTSH mejora la respuesta al tratamiento con radioyodo en pacientes con bocio multinodular t\u00f3xico de baja captaci\u00f3n"],"prefix":"10.1016","volume":"36","author":[{"given":"M.J.","family":"Azor\u00edn Belda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Mart\u00ednez Caballero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.C.","family":"Figueroa Ardila","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Mart\u00ednez Ram\u00edrez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.A.","family":"G\u00f3mez Jaramillo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.I.","family":"Dolado Ardit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Verd\u00fa Rico","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.remn.2016.05.009_bib0145","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.ciresp.2010.03.020","article-title":"Bocio intrator\u00e1cico. Revisi\u00f3n de la literatura m\u00e9dica","volume":"88","author":"De Aguiar-Quevedo","year":"2010","journal-title":"Cir Esp."},{"key":"10.1016\/j.remn.2016.05.009_bib0150","series-title":"Thyroid disorders \u2014 focus on hyperthyroidism","first-page":"25","article-title":"A Review of the pathogenesis and management of multinodular goiter","author":"Lam","year":"2014"},{"key":"10.1016\/j.remn.2016.05.009_bib0155","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1530\/EJE-08-0779","article-title":"Time to reconsider nonsurgical therapy of benign non-toxic multinodular goitre: Focus on recombinant human TSH augmented radioiodine therapy","volume":"160","author":"Fast","year":"2009","journal-title":"Eur J Endocrinol."},{"key":"10.1016\/j.remn.2016.05.009_bib0160","first-page":"623","article-title":"Hyperthyroidism: Diagnosis and treatment","volume":"72","author":"Reid","year":"2005","journal-title":"Am Fam Physician."},{"key":"10.1016\/j.remn.2016.05.009_bib0165","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S1575-0922(02)74452-5","article-title":"Utilidad del tratamiento con yodo radiactivo en el bocio multinodular normofuncionante","volume":"49","author":"G\u00f3mez-S\u00e1ez","year":"2002","journal-title":"Endocrinol Nutr."},{"key":"10.1016\/j.remn.2016.05.009_bib0170","doi-asserted-by":"crossref","first-page":"3424","DOI":"10.1210\/jc.2007-0501","article-title":"Improvement of goiter volume reduction after 0.3mg recombinant human thyrotropin-stimulated radioiodine therapy in patients with a very large goiter: A double-blinded, randomized trial","volume":"92","author":"Bonnema","year":"2007","journal-title":"J Clin Endocrinol Metab."},{"key":"10.1016\/j.remn.2016.05.009_bib0175","first-page":"847","article-title":"Iodine-131: Optimal therapy for hyperthyroidism in children and adolescents","volume":"20","author":"Freitas","year":"1979","journal-title":"J Nucl Med."},{"key":"10.1016\/j.remn.2016.05.009_bib0180","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1002\/ijc.2910500611","article-title":"Cancer mortality after iodine-131 therapy for hyperthyroidism","volume":"50","author":"Hall","year":"1992","journal-title":"Int J Cancer."},{"key":"10.1016\/j.remn.2016.05.009_bib0185","doi-asserted-by":"crossref","first-page":"2653","DOI":"10.1210\/jc.2011-3335","article-title":"Prestimulation with recombinant human thyrotropin (rhTSH) improves the long-term outcome of radioiodine therapy for multinodular nontoxic goiter","volume":"97","author":"Fast","year":"2012","journal-title":"J Clin Endocrinol Metab."},{"key":"10.1016\/j.remn.2016.05.009_bib0190","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1001\/archinte.166.14.1476","article-title":"Stimulation with 0.3-mg recombinant human thyrotropin prior to iodine 131 therapy to improve the size reduction of benign nontoxic nodular goiter: a prospective randomized double-blind trial","volume":"166","author":"Nielsen","year":"2006","journal-title":"Arch Intern Med."},{"key":"10.1016\/j.remn.2016.05.009_bib0195","doi-asserted-by":"crossref","first-page":"732","DOI":"10.2967\/jnumed.108.060152","article-title":"Optimizing 131I uptake after rhTSH stimulation in patients with nontoxic multinodular goiter: Evidence from a prospective, randomized, double-blind study","volume":"50","author":"Fast","year":"2009","journal-title":"J Nucl Med."},{"key":"10.1016\/j.remn.2016.05.009_bib0200","doi-asserted-by":"crossref","first-page":"3981","DOI":"10.1210\/jc.2008-0485","article-title":"Recombinant human thyrotropin-stimulated radioiodine therapy of large nodular goiters facilitates tracheal decompression and improves inspiration","volume":"93","author":"Bonnema","year":"2008","journal-title":"J Clin Endocrinol Metab."},{"key":"10.1016\/j.remn.2016.05.009_bib0205","doi-asserted-by":"crossref","first-page":"3121","DOI":"10.1210\/jc.2002-021554","article-title":"Pretreatment with a single, low dose of recombinant human thyrotropin allows dose reduction of radioiodine therapy in patients with nodular goiter","volume":"88","author":"Nieuwlaat","year":"2003","journal-title":"J Clin Endocrinol Metab."},{"key":"10.1016\/j.remn.2016.05.009_bib0210","unstructured":"CSN\/SEPR\/SEFM. Criterios de alta de pacientes y medidas para la protecci\u00f3n radiol\u00f3gica del p\u00fablico despu\u00e9s de tratamientos metab\u00f3licos con 131I. Octubre 2011."},{"key":"10.1016\/j.remn.2016.05.009_bib0215","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1080\/02841860600617084","article-title":"Radioiodine therapy in non-toxic multinodular goitre. The possibility of effect-amplification with recombinant human TSH (rhTSH)","volume":"45","author":"Bonnema","year":"2006","journal-title":"Acta Oncol."},{"key":"10.1016\/j.remn.2016.05.009_bib0220","first-page":"161","article-title":"Role of recombinant human TSH in the management of large euthyroid multinodular goitre: A new therapeutic option? Pros and cons","volume":"35","author":"Ceccarelli","year":"2010","journal-title":"Minerva Endocrinol."},{"key":"10.1016\/j.remn.2016.05.009_bib0225","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.ando.2011.03.018","article-title":"Radioiodine therapy of benign non-toxic goitre. Potential role of recombinant human TSH","volume":"72","author":"Fast","year":"2011","journal-title":"Ann Endocrinol."},{"key":"10.1016\/j.remn.2016.05.009_bib0230","doi-asserted-by":"crossref","first-page":"3719","DOI":"10.1210\/jc.2010-0634","article-title":"Recombinant human thyrotropin-stimulated radioiodine therapy of nodular goiter allows major reduction of the radiation burden with retained efficacy","volume":"95","author":"Fast","year":"2010","journal-title":"J Clin Endocrinol Metab."},{"key":"10.1016\/j.remn.2016.05.009_bib0235","first-page":"3592","article-title":"Administration of a single low dose of recombinant human thyrotropin significantly enhances thyroid radioiodide uptake in nontoxic nodular goiter","volume":"85","author":"Huysmans","year":"2000","journal-title":"J Clin Endocrinol Metab."},{"key":"10.1016\/j.remn.2016.05.009_bib0240","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD010622","article-title":"Recombinant human thyrotropin (rhTSH) aided radioiodine treatment for non-toxic multinodular goitre","author":"Ma","year":"2013","journal-title":"Cochrane Database Syst Rev."},{"key":"10.1016\/j.remn.2016.05.009_bib0245","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1210\/jc.2005-2137","article-title":"Transient goiter enlargement after administration of 0.3mg of recombinant human thyrotropin in patients with benign nontoxic nodular goiter: A randomized, double-blind, crossover trial","volume":"91","author":"Nielsen","year":"2006","journal-title":"J Clin Endocrinol Metab."},{"key":"10.1016\/j.remn.2016.05.009_bib0250","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1210\/jc.2004-1550","article-title":"Recombinant human thyrotropin markedly changes the 131I kinetics during 131I therapy of patients with nodular goiter: An evaluation by a randomized double-blinded trial","volume":"90","author":"Nielsen","year":"2005","journal-title":"J Clin Endocrinol Metab."},{"key":"10.1016\/j.remn.2016.05.009_bib0255","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1530\/acta.0.1220417","article-title":"Radioiodine therapy in voluminous multinodular non-toxic goitre","volume":"122","author":"Verelst","year":"1990","journal-title":"Acta Endocrinol."},{"key":"10.1016\/j.remn.2016.05.009_bib0260","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1089\/thy.2013.0370","article-title":"Long-term efficacy of modified-release recombinant human thyrotropin augmented radioiodine therapy for benign multinodular goiter: Results from a multicenter, international, randomized, placebo-controlled, dose-selection study","volume":"24","author":"Fast","year":"2014","journal-title":"Thyroid."},{"key":"10.1016\/j.remn.2016.05.009_bib0265","doi-asserted-by":"crossref","first-page":"5330","DOI":"10.1210\/jcem.86.11.8014","article-title":"Pretreatment with recombinant human TSH changes the regional distribution of radioiodine on thyroid scintigrams of nodular goiters","volume":"86","author":"Nieuwlaat","year":"2001","journal-title":"J Clin Endocrinol Metab."},{"key":"10.1016\/j.remn.2016.05.009_bib0270","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1530\/eje.1.02094","article-title":"Low-dose recombinant human thyrotropin-aided radioiodine treatment of large, multinodular goiters in elderly patients","volume":"154","author":"Cohen","year":"2006","journal-title":"Eur J Endocrinol."},{"key":"10.1016\/j.remn.2016.05.009_bib0275","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1210\/jc.2005-1986","article-title":"123I thyroid uptake and thyroid size at 24, 48, and 72hours after the administration of recombinant human thyroid-stimulating hormone to normal volunteers","volume":"91","author":"Pena","year":"2006","journal-title":"J Clin Endocrinol Metab."},{"key":"10.1016\/j.remn.2016.05.009_bib0280","doi-asserted-by":"crossref","first-page":"2218","DOI":"10.1007\/s00259-010-1536-8","article-title":"EANM procedure guidelines for therapy of benign thyroid disease","volume":"37","author":"Stokkel","year":"2010","journal-title":"Eur J Nucl Med Mol Imaging."}],"container-title":["Revista Espa\u00f1ola de Medicina Nuclear e Imagen Molecular"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2253654X16300385?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2253654X16300385?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,11]],"date-time":"2019-09-11T02:45:54Z","timestamp":1568169954000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2253654X16300385"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["S2253654X16300385"],"URL":"https:\/\/doi.org\/10.1016\/j.remn.2016.05.009","relation":{},"ISSN":["2253-654X"],"issn-type":[{"value":"2253-654X","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"La estimulaci\u00f3n previa con rhTSH mejora la respuesta al tratamiento con radioyodo en pacientes con bocio multinodular t\u00f3xico de baja captaci\u00f3n","name":"articletitle","label":"Article Title"},{"value":"Revista Espa\u00f1ola de Medicina Nuclear e Imagen Molecular","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.remn.2016.05.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Espa\u00f1a, S.L.U. y SEMNIM. All rights reserved.","name":"copyright","label":"Copyright"}]}}