{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T23:47:04Z","timestamp":1785714424553,"version":"3.56.0"},"reference-count":81,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Reproductive Biology"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1016\/j.repbio.2020.08.004","type":"journal-article","created":{"date-parts":[[2020,9,7]],"date-time":"2020-09-07T07:56:03Z","timestamp":1599465363000},"page":"512-519","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Elimination of stress factors by continuous embryo culture and its influence on in vitro fertilization outcomes"],"prefix":"10.1016","volume":"20","author":[{"given":"G\u00e1bor","family":"M\u00e1t\u00e9","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Attila","family":"T\u00f6r\u00f6k","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.repbio.2020.08.004_bib0005","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.repbio.2018.07.001","article-title":"The production of pig preimplantation embryos in vitro: current progress and future prospects","volume":"18","author":"Fowler","year":"2018","journal-title":"Reprod Biol"},{"issue":"2","key":"10.1016\/j.repbio.2020.08.004_bib0010","doi-asserted-by":"crossref","first-page":"275","DOI":"10.2478\/aoas-2013-0009","article-title":"Creation of cloned pig embryos using contact-inhibited or serum-starved fibroblast cells analysed intravitam for apoptosis occurrence","volume":"13","author":"Samiec","year":"2013","journal-title":"Ann Anim Sci"},{"issue":"2","key":"10.1016\/j.repbio.2020.08.004_bib0015","doi-asserted-by":"crossref","first-page":"90","DOI":"10.5653\/cerm.2017.44.2.90","article-title":"Evaluation of human embryo development in in vitro fertilization- and intracytoplasmic sperm injection-fertilized oocytes: a time-lapse study","volume":"44","author":"Kim","year":"2017","journal-title":"Clin Exp Reprod Med"},{"issue":"4","key":"10.1016\/j.repbio.2020.08.004_bib0020","first-page":"385","article-title":"Preimplantation developmental capability of cloned pig embryos derived from different types of nuclear donor somatic cells","volume":"10","author":"Samiec","year":"2010","journal-title":"Ann Anim Sci"},{"issue":"3","key":"10.1016\/j.repbio.2020.08.004_bib0025","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.repbio.2018.05.002","article-title":"An ICSI rate of 90% minimizes complete failed fertilization and provides satisfactory implantation rates without elevating fetal abnormalities","volume":"18","author":"Yovich","year":"2018","journal-title":"Reprod Biol"},{"issue":"1","key":"10.1016\/j.repbio.2020.08.004_bib0030","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1292\/jvms.18-0284","article-title":"Application of intracytoplasmic sperm injection to the embryo production in aged cows","volume":"81","author":"Magata","year":"2019","journal-title":"J Vet Med Sci"},{"issue":"3","key":"10.1016\/j.repbio.2020.08.004_bib0035","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1093\/humrep\/dex376","article-title":"Human oocyte calcium analysis predicts the response to assisted oocyte activation in patients experiencing fertilization failure after ICSI","volume":"33","author":"Ferrer-Buitrago","year":"2018","journal-title":"Hum Reprod"},{"issue":"4","key":"10.1016\/j.repbio.2020.08.004_bib0040","first-page":"399","article-title":"The use of different methods of oocyte activation for generation of porcine fibroblast cell nuclear-transferred embryos","volume":"10","author":"Samiec","year":"2010","journal-title":"Ann Anim Sci"},{"issue":"9","key":"10.1016\/j.repbio.2020.08.004_bib0045","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1093\/humrep\/dey258","article-title":"Artificial oocyte activation with SrCl2 or calcimycin after ICSI improves clinical and embryological outcomes compared with ICSI alone: results of a randomized clinical trial","volume":"33","author":"Fawzy","year":"2018","journal-title":"Hum Reprod"},{"key":"10.1016\/j.repbio.2020.08.004_bib0050","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.theriogenology.2017.04.022","article-title":"In vitro development and cytological quality of inter-species (porcine\u2192bovine) cloned embryos are affected by trichostatin A-dependent epigenomic modulation of adult mesenchymal stem cells","volume":"97","author":"Opiela","year":"2017","journal-title":"Theriogenology"},{"key":"10.1016\/j.repbio.2020.08.004_bib0055","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.theriogenology.2018.09.021","article-title":"A fast and reliable protocol for activation of porcine oocytes","volume":"123","author":"de Macedo","year":"2019","journal-title":"Theriogenology"},{"issue":"1","key":"10.1016\/j.repbio.2020.08.004_bib0060","first-page":"217","article-title":"Intrinsic and extrinsic molecular determinants or modulators for epigenetic remodeling and reprogramming of somatic cell-derived genome in mammalian nuclear-transferred oocytes and resultant embryos","volume":"21","author":"Samiec","year":"2018","journal-title":"Pol J Vet Sci"},{"issue":"1","key":"10.1016\/j.repbio.2020.08.004_bib0065","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1096\/fj.201900578RR","article-title":"Transcriptional memory inherited from donor cells is a developmental defect of bovine cloned embryos","volume":"34","author":"Zhou","year":"2020","journal-title":"FASEB J"},{"issue":"9","key":"10.1016\/j.repbio.2020.08.004_bib0070","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1111\/asj.13260","article-title":"Expression of pluripotency-related genes is highly dependent on trichostatin A-assisted epigenomic modulation of porcine mesenchymal stem cells analysed for apoptosis and subsequently used for generating cloned embryos","volume":"90","author":"Samiec","year":"2019","journal-title":"Anim Sci J"},{"key":"10.1016\/j.repbio.2020.08.004_bib0075","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1186\/s40659-015-0059-y","article-title":"In vitro fertilization (IVF) in mammals: epigenetic and developmental alterations. Scientific and bioethical implications for IVF in humans","volume":"48","author":"Ventura-Junc\u00e1","year":"2015","journal-title":"Biol Res"},{"issue":"3","key":"10.1016\/j.repbio.2020.08.004_bib0080","doi-asserted-by":"crossref","first-page":"623","DOI":"10.2478\/aoas-2018-0015","article-title":"Can reprogramming of overall epigenetic memory and specific parental genomic imprinting memory within donor cell-inherited nuclear genome be a major hindrance for the somatic cell cloning of mammals?\u2014a review","volume":"18","author":"Samiec","year":"2018","journal-title":"Ann Anim Sci"},{"issue":"5","key":"10.1016\/j.repbio.2020.08.004_bib0085","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1007\/s10815-017-0886-6","article-title":"Quantitative and qualitative changes of mitochondria in human preimplantation embryos","volume":"34","author":"Hashimoto","year":"2017","journal-title":"J Assist Reprod Genet"},{"issue":"1","key":"10.1016\/j.repbio.2020.08.004_bib0090","doi-asserted-by":"crossref","first-page":"127","DOI":"10.2478\/aoas-2018-0046","article-title":"Identifying biomarkers of autophagy and apoptosis in transfected nuclear donor cells and transgenic cloned pig embryos","volume":"19","author":"Lee","year":"2019","journal-title":"Ann Anim Sci"},{"issue":"2","key":"10.1016\/j.repbio.2020.08.004_bib0095","doi-asserted-by":"crossref","first-page":"213","DOI":"10.22358\/jafs\/67008\/2005","article-title":"The role of mitochondrial genome (mtDNA) in somatic and embryo cloning of mammals. A review","volume":"14","author":"Samiec","year":"2005","journal-title":"J Anim Feed Sci"},{"issue":"4","key":"10.1016\/j.repbio.2020.08.004_bib0100","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1111\/rda.13198","article-title":"m-carboxycinnamic acid bishydroxamide improves developmental competence, reduces apoptosis and alters epigenetic status and gene expression pattern in cloned buffalo (Bubalus bubalis) embryos","volume":"53","author":"Agrawal","year":"2018","journal-title":"Reprod Domest Anim"},{"issue":"3","key":"10.1016\/j.repbio.2020.08.004_bib0105","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1097\/GCO.0000000000000274","article-title":"Mitochondrial DNA as a biomarker for in-vitro fertilization outcome","volume":"28","author":"Seli","year":"2016","journal-title":"Curr Opin Obstet Gynecol"},{"issue":"9","key":"10.1016\/j.repbio.2020.08.004_bib0110","doi-asserted-by":"crossref","first-page":"Fmi","DOI":"10.1002\/mrd.22260","article-title":"Human somatic cell nuclear transfer: a scientist\u2019s perspective","volume":"80","author":"Clark","year":"2013","journal-title":"Mol Reprod Dev"},{"issue":"4","key":"10.1016\/j.repbio.2020.08.004_bib0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.cell.2018.01.020","article-title":"Cloning of macaque monkeys by somatic cell nuclear transfer","volume":"172","author":"Liu","year":"2018","journal-title":"Cell"},{"issue":"4","key":"10.1016\/j.repbio.2020.08.004_bib0120","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.repbio.2018.11.004","article-title":"Founding Pioneers of IVF: independent innovative researchers generating livebirths within 4 years of the first birth","volume":"18","author":"Yovich","year":"2018","journal-title":"Reprod Biol"},{"issue":"1","key":"10.1016\/j.repbio.2020.08.004_bib0125","first-page":"119","article-title":"The role of intracytoplasmic sperm injection in non-male factor infertility in advanced maternal age","volume":"32","author":"Tannus","year":"2017","journal-title":"Hum Reprod"},{"issue":"6","key":"10.1016\/j.repbio.2020.08.004_bib0130","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1016\/S0015-0282(01)02888-6","article-title":"Noninvasive assessment of human embryo nutrient consumption as a measure of developmental potential","volume":"76","author":"Gardner","year":"2001","journal-title":"Fertil Steril"},{"issue":"8","key":"10.1016\/j.repbio.2020.08.004_bib0135","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1093\/humrep\/der143","article-title":"Glucose consumption of single post-compaction human embryos is predictive of embryo sex and live birth outcome","volume":"26","author":"Gardner","year":"2011","journal-title":"Hum Reprod"},{"issue":"4","key":"10.1016\/j.repbio.2020.08.004_bib0140","first-page":"259","article-title":"Early human embryo metabolism","volume":"15","author":"Leese","year":"1993","journal-title":"Bio Assays"},{"issue":"2","key":"10.1016\/j.repbio.2020.08.004_bib0145","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1095\/biolreprod48.2.377","article-title":"Amino acids and ammonium regulate the development of mouse embryos in culture","volume":"48","author":"Gardner","year":"1993","journal-title":"Biol Reprod"},{"issue":"2","key":"10.1016\/j.repbio.2020.08.004_bib0150","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1530\/jrf.0.1020305","article-title":"Increase in postimplantation development of cultured mouse embryos by amino acids and induction of fetal retardation and exencephaly by ammonium ions","volume":"102","author":"Lane","year":"1994","journal-title":"J Reprod Fertil"},{"issue":"1","key":"10.1016\/j.repbio.2020.08.004_bib0155","first-page":"152","article-title":"The 2-cell block in CF1 mouse embryos is associated with an increase in glycolysis and a decrease in tricarboxylic acid (TCA) cycle activity: alleviation of the 2-cell block is associated with the restoration of in vivo metabolic pathway activities","volume":"48","author":"Gardner","year":"1993","journal-title":"Biol Reprod"},{"issue":"4","key":"10.1016\/j.repbio.2020.08.004_bib0160","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1093\/humrep\/15.4.896","article-title":"Intracellular pH regulation in human preimplantation embryos","volume":"15","author":"Phillips","year":"2000","journal-title":"Hum Reprod"},{"issue":"12","key":"10.1016\/j.repbio.2020.08.004_bib0165","doi-asserted-by":"crossref","first-page":"3441","DOI":"10.1093\/humrep\/13.12.3441","article-title":"Intracellular pH of the mouse preimplantation embryo: amino acids act as buffers of intracellular pH","volume":"13","author":"Edwards","year":"1998","journal-title":"Hum Reprod"},{"issue":"4","key":"10.1016\/j.repbio.2020.08.004_bib0170","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1002\/(SICI)1098-2795(199808)50:4<434::AID-MRD7>3.0.CO;2-J","article-title":"Intracellular pH of the preimplantation mouse embryo: effects of extracellular pH and weak acids","volume":"50","author":"Edwards","year":"1998","journal-title":"Mol Reprod Dev"},{"issue":"2","key":"10.1016\/j.repbio.2020.08.004_bib0175","doi-asserted-by":"crossref","first-page":"110","DOI":"10.5152\/jtgga.2011.25","article-title":"Embryo culture media for human IVF: which possibilities exist?","volume":"12","author":"Gruber","year":"2011","journal-title":"J Turk Ger Gynecol Assoc"},{"issue":"4","key":"10.1016\/j.repbio.2020.08.004_bib0180","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/j.fertnstert.2017.01.007","article-title":"Composition of single-step media used for human embryo culture","volume":"107","author":"Morbeck","year":"2017","journal-title":"Fertil Steril"},{"key":"10.1016\/j.repbio.2020.08.004_bib0185","first-page":"1","article-title":"Human blastocyst development: a randomized comparison of sibling zygotes cultured in Vitrolife G-TL\u2122 to Life Global\u00ae single-step media","volume":"2","author":"Schiewe","year":"2018","journal-title":"J Pregnancy Reprod"},{"issue":"9","key":"10.1016\/j.repbio.2020.08.004_bib0190","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1177\/1933719116687653","article-title":"Blastocyst development in a single medium compared to sequential media: a prospective study with sibling oocytes","volume":"24","author":"Sfontouris","year":"2017","journal-title":"Reprod Sci"},{"key":"10.1016\/j.repbio.2020.08.004_bib0195","doi-asserted-by":"crossref","first-page":"S253","DOI":"10.1016\/j.fertnstert.2013.07.1192","article-title":"Blastocyst outcomes after sequential media culture vs single step media culture in a human IVF program","volume":"100","author":"Velez de la Calle","year":"2013","journal-title":"Fertil Steril"},{"issue":"3","key":"10.1016\/j.repbio.2020.08.004_bib0200","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1007\/s10815-018-1195-4","article-title":"Continuous embryo culture elicits higher blastulation but similar cumulative delivery rates than sequential: a large prospective study","volume":"35","author":"Cimadomo","year":"2018","journal-title":"J Assist Reprod Genet"},{"issue":"3","key":"10.1016\/j.repbio.2020.08.004_bib0205","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.1016\/j.fertnstert.2012.01.008","article-title":"Improved blastocyst development using a single step medium versus a sequential medium","volume":"97","author":"Khoury","year":"2012","journal-title":"Fertil Steril"},{"issue":"3","key":"10.1016\/j.repbio.2020.08.004_bib0210","doi-asserted-by":"crossref","first-page":"S168","DOI":"10.1016\/j.fertnstert.2012.07.620","article-title":"Single-step vs. two-step media: are there any differences in embryonic development?","volume":"98","author":"Liebermann","year":"2012","journal-title":"Fertil Steril"},{"issue":"2","key":"10.1016\/j.repbio.2020.08.004_bib0215","first-page":"128","article-title":"Comparison of two commercial embryo culture media (SAGE-1 step single medium vs. G1-PLUSTM\/G2-PLUSTM sequential media): influence on in vitro fertilization outcomes and human embryo quality","volume":"22","author":"L\u00f3pez-Pelayo","year":"2018","journal-title":"JBRA Assist Reprod"},{"key":"10.1016\/j.repbio.2020.08.004_bib0220","doi-asserted-by":"crossref","first-page":"S431","DOI":"10.1016\/j.fertnstert.2008.07.1210","article-title":"Comparison of single and sequential culture systems on embryo development, pregnancy and implantation rates using sibling oocytes","volume":"90","author":"Nanassy","year":"2008","journal-title":"Fertil Steril"},{"issue":"3","key":"10.1016\/j.repbio.2020.08.004_bib0225","doi-asserted-by":"crossref","first-page":"240","DOI":"10.5935\/1518-0557.20170045","article-title":"Single versus sequential culture medium: which is better at improving ongoing pregnancy rates? A systematic review and meta-analysis","volume":"21","author":"Dieamant","year":"2017","journal-title":"JBRA Assist Reprod"},{"issue":"1","key":"10.1016\/j.repbio.2020.08.004_bib0230","first-page":"49","article-title":"Embryo development until blastocyst stage with and without renewal of single medium on day 3","volume":"22","author":"Pe\u00f1a","year":"2018","journal-title":"JBRA Assist Reprod"},{"key":"10.1016\/j.repbio.2020.08.004_bib0235","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/978-1-61779-971-6_12","article-title":"Culture systems: single step","volume":"912","author":"Machtinger","year":"2012","journal-title":"Methods Mol Biol"},{"issue":"4","key":"10.1016\/j.repbio.2020.08.004_bib0240","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1002\/bdrc.21022","article-title":"Preimplantation stress and development","volume":"96","author":"Feuer","year":"2013","journal-title":"Birth Defects Res C Embryo Today"},{"issue":"3","key":"10.1016\/j.repbio.2020.08.004_bib0245","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/j.fertnstert.2013.11.004","article-title":"The nature of aneuploidy with increasing age of the female partner: a review of 15,169 consecutive trophectoderm biopsies evaluated with comprehensive chromosomal screening","volume":"101","author":"Franasiak","year":"2014","journal-title":"Fertil Steril"},{"issue":"1","key":"10.1016\/j.repbio.2020.08.004_bib0250","first-page":"5","article-title":"Methods of embryo scoring in in vitro fertilization","volume":"4","author":"B\u0105czkowski","year":"2004","journal-title":"Reprod Biol"},{"issue":"1","key":"10.1016\/j.repbio.2020.08.004_bib0255","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1242\/dev.112.1.99","article-title":"The roles of pyruvate, lactate and glucose during preimplantation development of embryos from F1 hybrid mice in vitro","volume":"112","author":"Brown","year":"1991","journal-title":"Development"},{"issue":"6","key":"10.1016\/j.repbio.2020.08.004_bib0260","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1016\/S0015-0282(16)60377-1","article-title":"Potential risk of light and room temperature exposure to preimplantation embryos","volume":"50","author":"Fischer","year":"1998","journal-title":"Fertil Steril"},{"issue":"4","key":"10.1016\/j.repbio.2020.08.004_bib0265","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1016\/j.fertnstert.2007.01.036","article-title":"Light intensity and wavelength during embryo manipulation are important factors for maintaining viability of preimplantation embryos in vitro","volume":"88","author":"Oh","year":"2007","journal-title":"Fertil Steril"},{"issue":"1","key":"10.1016\/j.repbio.2020.08.004_bib0270","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/0891-5849(93)90126-F","article-title":"Increased generation of reactive oxygen species in embryos cultured in vitro","volume":"15","author":"Goto","year":"1993","journal-title":"Free Radic Biol Med"},{"issue":"2","key":"10.1016\/j.repbio.2020.08.004_bib0275","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1095\/biolreprod67.2.534","article-title":"Full-term development of golden hamster oocytes following intracytoplasmic sperm head injection","volume":"67","author":"Yamauchi","year":"2002","journal-title":"Biol Reprod"},{"issue":"2-3","key":"10.1016\/j.repbio.2020.08.004_bib0280","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/s10815-006-9081-x","article-title":"Light exposure of the ovum and preimplantation embryo during ART procedures","volume":"24","author":"Ottosen","year":"2007","journal-title":"J Assist Reprod Genet"},{"issue":"36","key":"10.1016\/j.repbio.2020.08.004_bib0285","doi-asserted-by":"crossref","first-page":"14289","DOI":"10.1073\/pnas.0706687104","article-title":"Effects of light on development of mammalian zygotes","volume":"104","author":"Takenaka","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.repbio.2020.08.004_bib0290","series-title":"Troubleshooting and problem-solving in the IVF laboratory","first-page":"104","article-title":"The effects of light on embryos and embryo culture","author":"Pomeroy","year":"2015"},{"issue":"1","key":"10.1016\/j.repbio.2020.08.004_bib0295","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/S0015-0282(16)53644-9","article-title":"Transient cooling to room temperature can cause irreversible disruption of the meiotic spindle in the human oocyte","volume":"54","author":"Pickering","year":"1990","journal-title":"Fertil Steril"},{"issue":"4","key":"10.1016\/j.repbio.2020.08.004_bib0300","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1017\/S0967199400002793","article-title":"The effect of temperature fluctuations on the cytoskeletal organisation and chromosomal constitution of the human oocyte","volume":"3","author":"Almeida","year":"1995","journal-title":"Zygote"},{"issue":"11","key":"10.1016\/j.repbio.2020.08.004_bib0305","doi-asserted-by":"crossref","first-page":"2374","DOI":"10.1093\/humrep\/16.11.2374","article-title":"Limited recovery of meiotic spindles in living human oocytes after cooling\u2013rewarming observed using polarized light microscopy","volume":"16","author":"Wang","year":"2001","journal-title":"Hum Reprod"},{"issue":"6","key":"10.1016\/j.repbio.2020.08.004_bib0310","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1016\/S0015-0282(02)03117-5","article-title":"Rigorous thermal control during intracytoplasmic sperm injection stabilizes the meiotic spindle and improves fertilization and pregnancy rates","volume":"77","author":"Wang","year":"2002","journal-title":"Fertil Steril"},{"issue":"3","key":"10.1016\/j.repbio.2020.08.004_bib0315","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/j.fertnstert.2014.06.009","article-title":"Examining the temperature of embryo culture in in vitro fertilization: a randomized controlled trial comparing traditional core temperature (37\u00b0C) to a more physiologic, cooler temperature (36\u00b0C)","volume":"102","author":"Hong","year":"2014","journal-title":"Fertil Steril"},{"issue":"7","key":"10.1016\/j.repbio.2020.08.004_bib0320","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1590\/S0100-879X2005000700003","article-title":"Oxidative stress: molecular perception and transduction of signals triggering antioxidant gene defenses","volume":"38","author":"Scandalios","year":"2005","journal-title":"Braz J Med Biol Res"},{"key":"10.1016\/j.repbio.2020.08.004_bib0325","series-title":"Free radicals in biology and medicine","author":"Halliwell","year":"2007"},{"issue":"3","key":"10.1016\/j.repbio.2020.08.004_bib0330","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1095\/biolreprod53.3.532","article-title":"Expression of genes encoding antioxidant enzymes in preimplantation mouse and cow embryos and primary bovine oviduct cultures employed for embryo coculture","volume":"53","author":"Harvey","year":"1995","journal-title":"Biol Reprod"},{"issue":"3","key":"10.1016\/j.repbio.2020.08.004_bib0335","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.rbmo.2010.04.028","article-title":"Time-lapse analysis of mouse embryo development in oxygen gradients","volume":"21","author":"Wale","year":"2010","journal-title":"Reprod Biomed Online"},{"issue":"1","key":"10.1016\/j.repbio.2020.08.004_bib0340","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1093\/humupd\/dmv034","article-title":"The effects of chemical and physical factors on mammalian embryo culture and their importance for the practice of assisted human reproduction","volume":"22","author":"Wale","year":"2016","journal-title":"Hum Reprod Update"},{"issue":"1","key":"10.1016\/j.repbio.2020.08.004_bib0345","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.fertnstert.2006.05.066","article-title":"Effect of reduced oxygen concentrations on the outcome of in vitro fertilization","volume":"87","author":"Kea","year":"2007","journal-title":"Fertil Steril"},{"issue":"4","key":"10.1016\/j.repbio.2020.08.004_bib0350","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s12522-012-0126-9","article-title":"Effect of polyvinylpyrrolidone on sperm function and early embryonic development following intracytoplasmic sperm injection in human assisted reproduction","volume":"11","author":"Kato","year":"2012","journal-title":"Reprod Med Biol"},{"issue":"2","key":"10.1016\/j.repbio.2020.08.004_bib0355","first-page":"131","article-title":"Comparison of conventional IVF versus ICSI in non-male factor, normoresponder patients","volume":"10","author":"Eftekhar","year":"2012","journal-title":"Iran J Reprod Biomed"},{"issue":"4","key":"10.1016\/j.repbio.2020.08.004_bib0360","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1016\/j.fertnstert.2007.02.067","article-title":"Oxidative stress and tumor necrosis factor-alpha-induced alterations in metaphase II mouse oocyte spindle structure","volume":"88","author":"Choi","year":"2007","journal-title":"Fertil Steril"},{"issue":"7","key":"10.1016\/j.repbio.2020.08.004_bib0365","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1016\/j.freeradbiomed.2007.11.014","article-title":"Reactive oxygen species and oocyte aging: role of superoxide, hydrogenperoxide, and hypochlorousacid","volume":"44","author":"Goud","year":"2008","journal-title":"Free Radic Biol Med"},{"issue":"14","key":"10.1016\/j.repbio.2020.08.004_bib0370","doi-asserted-by":"crossref","first-page":"17393","DOI":"10.18632\/oncotarget.8165","article-title":"C-phycocyanin protects against low fertility by inhibiting reactive oxygen species in aging mice","volume":"7","author":"Li","year":"2016","journal-title":"Oncotarget"},{"issue":"5","key":"10.1016\/j.repbio.2020.08.004_bib0375","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1093\/humrep\/des019","article-title":"Delay in oocyte aging in mice by the antioxidant N-acetyl-L-cysteine (NAC)","volume":"27","author":"Liu","year":"2012","journal-title":"Hum Reprod"},{"issue":"1","key":"10.1016\/j.repbio.2020.08.004_bib0380","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1016\/j.fertnstert.2005.08.060","article-title":"Arsenite induces aberrations in meiosis that can be prevented by coadministration of N-acetylcysteine in mice","volume":"85","author":"Navarro","year":"2006","journal-title":"Fertil Steril"},{"issue":"1","key":"10.1016\/j.repbio.2020.08.004_bib0385","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-06372-z","article-title":"The lipidperoxidation product 4-hydroxynonenal contributes to oxidative stress-mediated deterioration of the ageing oocyte","volume":"7","author":"Mihalas","year":"2017","journal-title":"Sci Rep"},{"issue":"1","key":"10.1016\/j.repbio.2020.08.004_bib0390","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/s10815-019-01621-8","article-title":"The impact of culture conditions on blastocyst formation and aneuploidy rates: a comparison between single-step and sequential media in a large academic practice","volume":"37","author":"Deng","year":"2020","journal-title":"J Assist Reprod Genet"},{"issue":"4","key":"10.1016\/j.repbio.2020.08.004_bib0395","doi-asserted-by":"crossref","first-page":"e361","DOI":"10.1016\/j.fertnstert.2018.07.1009","article-title":"Stress Relief: can continous culture in a low lactate culture media reduce numerical chromosomal abnormaliteis and therefor improve euploidy rates","volume":"110","author":"Vermilya","year":"2018","journal-title":"Fertil Steril"},{"issue":"5","key":"10.1016\/j.repbio.2020.08.004_bib0400","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1016\/j.fertnstert.2016.01.005","article-title":"Sequential versus Monophasic Media Impact Trial (SuMMIT): a paired randomized controlled trial comparing a sequential media system to a monophasic medium","volume":"105","author":"Werner","year":"2016","journal-title":"Fertil Steril"},{"issue":"6","key":"10.1016\/j.repbio.2020.08.004_bib0405","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1093\/biolre\/ioz125","article-title":"Sperm chromosomal abnormalities and their contribution to human embryo aneuploidy","volume":"101","author":"Rodrigo","year":"2019","journal-title":"Biol Reprod"}],"container-title":["Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1642431X20302692?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1642431X20302692?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T10:19:50Z","timestamp":1761646790000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1642431X20302692"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":81,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["S1642431X20302692"],"URL":"https:\/\/doi.org\/10.1016\/j.repbio.2020.08.004","relation":{},"ISSN":["1642-431X"],"issn-type":[{"value":"1642-431X","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Elimination of stress factors by continuous embryo culture and its influence on in vitro fertilization outcomes","name":"articletitle","label":"Article Title"},{"value":"Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.repbio.2020.08.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Society for Biology of Reproduction & the Institute of Animal Reproduction and Food Research of Polish Academy of Sciences in Olsztyn. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}