{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T18:19:01Z","timestamp":1778177941254,"version":"3.51.4"},"reference-count":45,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100015241","name":"Society for the Study of Reproduction","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100015241","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Reproductive Biology"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.repbio.2024.100932","type":"journal-article","created":{"date-parts":[[2024,8,18]],"date-time":"2024-08-18T06:02:56Z","timestamp":1723960976000},"page":"100932","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["The effect of supplementing freezing extender with Mn2+-, Zn2+- or Cu2+-nanosuccinate on select post-thaw characteristics of ram semen"],"prefix":"10.1016","volume":"24","author":[{"given":"Olha","family":"Sharan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasyl","family":"Stefanyk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pawel M.","family":"Bartlewski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2299-4811","authenticated-orcid":false,"given":"Mykola","family":"Sharan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.repbio.2024.100932_bib1","doi-asserted-by":"crossref","first-page":"162","DOI":"10.2174\/1874255601103010162","article-title":"A review of advances in artificial insemination (AI) and embryo transfer (ET) in sheep, with the special reference to hormonal induction of cervical dilation and its implications for controlled animal reproduction and surgical techniques","author":"Candappa","year":"2011","journal-title":"Open Reprod Sci J"},{"issue":"Suppl. 4","key":"10.1016\/j.repbio.2024.100932_bib2","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1111\/rda.13523","article-title":"Current challenges in sheep artificial insemination: a particular insight","volume":"54","author":"Alvarez","year":"2019","journal-title":"Reprod Domest Anim"},{"key":"10.1016\/j.repbio.2024.100932_bib3","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1186\/s40104-019-0395-9","article-title":"Bovine sperm selection procedure prior to cryopreservation for improvement of post-thawed semen quality and fertility","volume":"10","author":"Nagata","year":"2019","journal-title":"J Anim Sci Biotechnol"},{"key":"10.1016\/j.repbio.2024.100932_bib4","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/0378-4320(94)01327-I","article-title":"Frozen storage of Ram Semen I. Processing, freezing, thawing and fertility after cervical insemination","volume":"34","author":"Salamon","year":"1995","journal-title":"Anim Reprod Sci"},{"issue":"2","key":"10.1016\/j.repbio.2024.100932_bib5","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/s10561-005-0275-8","article-title":"Cryopreservation and sperm DNA integrity","volume":"7","author":"Gandini","year":"2006","journal-title":"Cell Tissue Bank"},{"issue":"8","key":"10.1016\/j.repbio.2024.100932_bib6","doi-asserted-by":"crossref","first-page":"2781","DOI":"10.3390\/ijms21082781","article-title":"Sperm cryodamage in ruminants: understanding the molecular changes induced by the cryopreservation process to optimize sperm quality","volume":"21","author":"Peris-Frau","year":"2020","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.repbio.2024.100932_bib7","doi-asserted-by":"crossref","first-page":"383","DOI":"10.2754\/avb200776030383","article-title":"Effects of oxidized glutathione, bovine serum albumin, cysteine and lycopene on the quality of frozen-thawed ram semen","volume":"76","author":"Uysal","year":"2007","journal-title":"Acta Vet Brno"},{"issue":"11","key":"10.1016\/j.repbio.2024.100932_bib8","doi-asserted-by":"crossref","first-page":"218","DOI":"10.20546\/ijcmas.2017.611.026","article-title":"Importance of trace minerals in the ration of breeding bull-a review","volume":"6","author":"Pal","year":"2017","journal-title":"Int J Curr Microbiol Appl Sci"},{"key":"10.1016\/j.repbio.2024.100932_bib9","doi-asserted-by":"crossref","first-page":"1964","DOI":"10.3923\/pjbs.2008.1964.1968","article-title":"Effects of copper and superoxide dismutase content of seminal plasma on buffalo semen characteristics","volume":"11","author":"Eghbali","year":"2008","journal-title":"Pak J Biol Sci"},{"key":"10.1016\/j.repbio.2024.100932_bib10","first-page":"301","article-title":"Zewnatrzkom\u00f3rkowa dysmutaza ponadtlenkowa (EC-SOD)-budowa, w\u0142a\u015bciwo\u015bci i funkcje [Extracellular superoxide dismutase (EC-SOD)-structure, properties and functions]","volume":"58","author":"Skrzycki","year":"2004","journal-title":"Post Hig Med Dosw (Online)"},{"key":"10.1016\/j.repbio.2024.100932_bib11","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.cryobiol.2019.11.043","article-title":"Total and specific activities of superoxide dismutase (SOD) in seminal plasma are related with the cryotolerance of jackass spermatozoa","volume":"92","author":"Papas","year":"2020","journal-title":"Cryobiology"},{"issue":"1","key":"10.1016\/j.repbio.2024.100932_bib12","first-page":"68","article-title":"Effect of supplemental trace mineral source on bull semen quality","volume":"30","author":"Rowe","year":"2014","journal-title":"Appl Anim Sci"},{"key":"10.1016\/j.repbio.2024.100932_bib13","article-title":"Kinematics motility of frozen-thawed X and Y sperm of Sumba Ongole bull","volume":"387","author":"Maulana","year":"2019","journal-title":"IOP Conf Ser: Earth Environ Sci"},{"issue":"16","key":"10.1016\/j.repbio.2024.100932_bib14","first-page":"107","article-title":"Nanotechnologies of micronutrients: problems, prospects and ways to eliminate the deficiency of macro- and microelements","volume":"1","author":"Serdyuk","year":"2010","journal-title":"J Acad Med Sci Ukr"},{"issue":"11","key":"10.1016\/j.repbio.2024.100932_bib15","first-page":"5","article-title":"Nanotechnologies and their application in animal husbandry and veterinary medicine","volume":"93","author":"Vlizlo","year":"2015","journal-title":"Bull Anim Sci"},{"issue":"7","key":"10.1016\/j.repbio.2024.100932_bib16","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0041030","article-title":"Glucose is a pH-dependent motor for sperm beat frequency during early activation","volume":"7","author":"Mannowetz","year":"2012","journal-title":"PLoS One"},{"issue":"9","key":"10.1016\/j.repbio.2024.100932_bib17","doi-asserted-by":"crossref","first-page":"1796","DOI":"10.3390\/antiox11091796","article-title":"Sperm quality affected by naturally occurring chemical elements in bull seminal plasma","volume":"11","author":"Tirp\u00e1k","year":"2022","journal-title":"Antioxidants (Basel)"},{"issue":"4","key":"10.1016\/j.repbio.2024.100932_bib18","doi-asserted-by":"crossref","first-page":"12","DOI":"10.15407\/animbiol24.04.012","article-title":"Hematological indicators and sperm quality of rams during the sexual rest period when fed a liposomal vitamin and mineral supplement","volume":"24","author":"Sharan","year":"2022","journal-title":"Anim Biol"},{"key":"10.1016\/j.repbio.2024.100932_bib19","unstructured":"Kosinov M.V., Kaplunenko V.G., inventors; Kosinov MV assignee. Ultrapure aqueous solution of metal nanocarboxylate. Patent of Ukraine for utility model No. 39397. IPC (2006): \u042107\u0421 51\/41, \u042107F 5\/00, C07F 15\/00; 2009 Feb 25. Ukrainian."},{"key":"10.1016\/j.repbio.2024.100932_bib20","unstructured":"Kosinov M.V., Kaplunenko V.G., inventors; Kosinov MV assignee. Patent of Ukraine for coris model No. 38391. IPC (2006): \u042107\u0421 51\/41, \u042107F 5\/00, C07F 15\/00, C07C 53\/126 (2008.01), C07C 53\/10 (2008.01), A23L 1\/00, B83 3\/00. Method for the extraction of metal carboxylates \"Nanotechnology for the extraction of metal carboxylates\"; 2009 Jan 12. Ukrainian."},{"key":"10.1016\/j.repbio.2024.100932_bib21","first-page":"46","article-title":"O znachenii akrosomyi v otsenke semeni samtsov [The importance of the acrosome in the estimation of the semen]","volume":"9","author":"Sokolovskaya","year":"1981","journal-title":"Zhyvotnovodstvo"},{"issue":"2","key":"10.1016\/j.repbio.2024.100932_bib22","doi-asserted-by":"crossref","first-page":"147","DOI":"10.3109\/19396360903582216","article-title":"Adverse effects of low-level heavy metal exposure on male reproductive function","volume":"56","author":"Wirth","year":"2010","journal-title":"Syst Biol Reprod Med"},{"issue":"1","key":"10.1016\/j.repbio.2024.100932_bib23","first-page":"16","article-title":"A method of determining catalase activity.","author":"Koroliuk","year":"1988","journal-title":"Lab Delo"},{"issue":"8","key":"10.1016\/j.repbio.2024.100932_bib24","doi-asserted-by":"crossref","first-page":"1682","DOI":"10.1016\/j.theriogenology.2012.06.007","article-title":"The cryobiology of spermatozoa","volume":"78","author":"Benson","year":"2012","journal-title":"Theriogenology"},{"key":"10.1016\/j.repbio.2024.100932_bib25","unstructured":"Tekin N., Uysal O., Akcay E., Yavas I. Effects of different taurine doses and freezing rate on freezing of ram semen. Ankara \u00dcniversitesi Veteriner Fak\u00fcltesi Dergisi 2006;53:179\u221284. Turkish."},{"issue":"3","key":"10.1016\/j.repbio.2024.100932_bib26","doi-asserted-by":"crossref","first-page":"353","DOI":"10.3109\/01480545.2012.710631","article-title":"Environmental and occupational exposure of metals and their role in male reproductive functions. A review","volume":"36","author":"Sengupta","year":"2013","journal-title":"Drug Chem Toxicol"},{"issue":"41","key":"10.1016\/j.repbio.2024.100932_bib27","doi-asserted-by":"crossref","first-page":"15148","DOI":"10.1073\/pnas.0604641103","article-title":"Mitochondria-related male infertility","volume":"103","author":"Nakada","year":"2006","journal-title":"PNAS"},{"issue":"2","key":"10.1016\/j.repbio.2024.100932_bib28","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.ijvsm.2018.09.001","article-title":"Perspectives of nanotechnology in male fertility and sperm function","volume":"6","author":"Falchi","year":"2018","journal-title":"Int J Vet Sci Med"},{"key":"10.1016\/j.repbio.2024.100932_bib29","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.theriogenology.2018.12.017","article-title":"Impact of selenium nanoparticles in semen extender on bull sperm quality after cryopreservation","volume":"126","author":"Khalil","year":"2019","journal-title":"Theriogenology"},{"issue":"4","key":"10.1016\/j.repbio.2024.100932_bib30","doi-asserted-by":"crossref","first-page":"1758","DOI":"10.3390\/ijerph18041758","article-title":"Perspectives of nanoparticles in male infertility: evidence for induced abnormalities in sperm production","volume":"18","author":"Iftikhar","year":"2012","journal-title":"Int J Environ Res Public Health"},{"key":"10.1016\/j.repbio.2024.100932_bib31","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/s40104-017-0157-5","article-title":"Current and future prospects for nanotechnology in animal production","volume":"8","author":"Hill","year":"2017","journal-title":"J Anim Sci Biotechnol"},{"issue":"5","key":"10.1016\/j.repbio.2024.100932_bib32","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1007\/s11250-021-02951-5","article-title":"Role of nanotechnology in animal production and veterinary medicine","volume":"53","author":"Ali","year":"2012","journal-title":"Trop Anim Health Prod"},{"issue":"1","key":"10.1016\/j.repbio.2024.100932_bib33","doi-asserted-by":"crossref","first-page":"27","DOI":"10.30574\/msarr.2022.4.1.0082","article-title":"Application of nanoparticles in the veterinary medicine","volume":"4","author":"Kareem","year":"2022","journal-title":"Magna Sci Adv Res Rev"},{"key":"10.1016\/j.repbio.2024.100932_bib34","doi-asserted-by":"crossref","unstructured":"Yaremchuk I., Kuzmina N., Ostapiv D., Sharan \u041c, Kava S. Oxidative processes intensity and quality of bull semen when adding microelements nanosuccinate compounds. Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies. Series: Veterinary Sciences. 2017;19(77):185\u22129. Ukrainian. doi.org\/10.15421\/nvlvet7740.","DOI":"10.15421\/nvlvet7740"},{"issue":"1","key":"10.1016\/j.repbio.2024.100932_bib35","doi-asserted-by":"crossref","first-page":"23","DOI":"10.15407\/animbiol23.01.023","article-title":"Quality of deconserved bull sperm for the action of nanosuccinates Zn, Cu and Mn in the diluents","volume":"23","author":"\u041aornyat","year":"2021","journal-title":"Anim Biol"},{"key":"10.1016\/j.repbio.2024.100932_bib36","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.anireprosci.2013.02.007","article-title":"Fertility of cryopreserved ovine semen is determined by sperm velocity","volume":"138","author":"Del Olmo","year":"2013","journal-title":"Anim Reprod Sci"},{"key":"10.1016\/j.repbio.2024.100932_bib37","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.theriogenology.2013.09.004","article-title":"Computer-assisted sperm analysis (CASA): capabilities and potential developments","volume":"81","author":"Amann","year":"2014","journal-title":"Theriogenology"},{"issue":"5","key":"10.1016\/j.repbio.2024.100932_bib38","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1530\/REP-15-0596","article-title":"D-penicillamine prevents ram sperm agglutination by reducing the disulphide bonds of a copper-binding sperm protein","volume":"151","author":"Leahy","year":"2016","journal-title":"Reproduction"},{"issue":"5","key":"10.1016\/j.repbio.2024.100932_bib39","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1093\/humupd\/dmh034","article-title":"Regulation of sperm function by reactive oxygen species","volume":"10","author":"Ford","year":"2004","journal-title":"Hum Reprod Update"},{"issue":"1","key":"10.1016\/j.repbio.2024.100932_bib40","doi-asserted-by":"crossref","first-page":"60","DOI":"10.5173\/ceju.2013.01.art19","article-title":"The role of oxidative stress and antioxidants in male fertility","volume":"66","author":"Walczak-Jedrzejowska","year":"2013","journal-title":"Cent Eur J Urol"},{"issue":"20","key":"10.1016\/j.repbio.2024.100932_bib41","first-page":"11919","article-title":"Superoxide dismutase undergoes proteolysis and fragmentation following oxidative modification and inactivation","volume":"265","author":"Salo","year":"1990","journal-title":"J Biol Chem 1990"},{"issue":"3","key":"10.1016\/j.repbio.2024.100932_bib42","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1093\/humrep\/17.3.704","article-title":"The effects of cryopreservation on sperm morphology, motility and mitochondrial function","volume":"17","author":"O\u2019Connell","year":"2002","journal-title":"Hum Reprod"},{"issue":"9","key":"10.1016\/j.repbio.2024.100932_bib43","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1016\/j.theriogenology.2009.12.007","article-title":"Effects of different cryoprotective agents on ram sperm morphology and DNA integrity","volume":"73","author":"Nur","year":"2010","journal-title":"Theriogenology"},{"key":"10.1016\/j.repbio.2024.100932_bib44","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0300-483X(03)00159-8","article-title":"Copper toxicity, oxidative stress, and antioxidant nutrients","volume":"189","author":"Gaetke","year":"2003","journal-title":"Toxicology"},{"issue":"5","key":"10.1016\/j.repbio.2024.100932_bib45","doi-asserted-by":"crossref","first-page":"804","DOI":"10.3390\/cells12050804","article-title":"Polyunsaturated fatty acids drive lipid peroxidation during ferroptosis","volume":"12","author":"Mortensen","year":"2023","journal-title":"Cells"}],"container-title":["Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1642431X24000780?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1642431X24000780?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T19:36:25Z","timestamp":1774899385000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1642431X24000780"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":45,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["S1642431X24000780"],"URL":"https:\/\/doi.org\/10.1016\/j.repbio.2024.100932","relation":{},"ISSN":["1642-431X"],"issn-type":[{"value":"1642-431X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effect of supplementing freezing extender with Mn2+-, Zn2+- or Cu2+-nanosuccinate on select post-thaw characteristics of ram semen","name":"articletitle","label":"Article Title"},{"value":"Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.repbio.2024.100932","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Society for Biology of Reproduction & the Institute of Animal Reproduction and Food Research of Polish Academy of Sciences in Olsztyn. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"100932"}}