{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T11:47:33Z","timestamp":1785844053586,"version":"3.56.0"},"reference-count":67,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Reproductive Biology"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.repbio.2026.101209","type":"journal-article","created":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T13:40:27Z","timestamp":1773754827000},"page":"101209","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Artificial ovary systems for fertility preservation: Current advances, bioengineering strategies, and translational perspectives"],"prefix":"10.1016","volume":"26","author":[{"given":"Anca","family":"Huniadi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2747-1411","authenticated-orcid":false,"given":"Viorela-Romina","family":"Murvai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioana Alexandra","family":"Zaha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7701-2307","authenticated-orcid":false,"given":"Liliana","family":"Sachelarie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Otilia","family":"\u0162ica","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ovidiu","family":"\u0162ica","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreea","family":"Carp-Veliscu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.repbio.2026.101209_bib1","first-page":"543","article-title":"Transplantation of an alginate-matrix-based 3D artificial ovary restores endocrine function and folliculogenesis in mice","volume":"27","author":"Vanacker","year":"2010","journal-title":"J Assist Reprod Genet"},{"key":"10.1016\/j.repbio.2026.101209_bib2","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.actbio.2021.08.026","article-title":"A review on biomaterials for ovarian tissue engineering","volume":"135","author":"Dadashzadeh","year":"2021","journal-title":"Acta Biomater"},{"issue":"23\u201324","key":"10.1016\/j.repbio.2026.101209_bib3","doi-asserted-by":"crossref","first-page":"3095","DOI":"10.1089\/ten.tea.2011.0204","article-title":"Fibrin encapsulation and vascular endothelial growth factor delivery promotes ovarian graft survival in mice","volume":"17","author":"Shikanov","year":"2011","journal-title":"Tissue Eng Part A"},{"issue":"5","key":"10.1016\/j.repbio.2026.101209_bib4","doi-asserted-by":"crossref","first-page":"355","DOI":"10.3390\/cells14050355","article-title":"Ovarian mechanobiology: understanding the interplay between mechanics and follicular development","volume":"14","author":"Wang","year":"2025","journal-title":"Cells"},{"issue":"20","key":"10.1016\/j.repbio.2026.101209_bib5","doi-asserted-by":"crossref","first-page":"2748","DOI":"10.3390\/healthcare11202748","article-title":"Innovative strategies for fertility preservation in female cancer survivors: new hope from artificial ovary construction and stem cell-derived neo-folliculogenesis","volume":"11","author":"Canosa","year":"2023","journal-title":"Healthcare"},{"key":"10.1016\/j.repbio.2026.101209_bib6","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/s12938-025-01392-7","article-title":"Preparation and characterization of human decellularized ovarian scaffold based on supercritical carbon dioxide protocol","volume":"24","author":"Hosseinpour","year":"2025","journal-title":"Biomed Eng Online"},{"key":"10.1016\/j.repbio.2026.101209_bib7","first-page":"472","article-title":"Reconstructing the female reproductive system using 3D bioprinting: recent advances and challenges","volume":"31","author":"Yi","year":"2025","journal-title":"Bioact Mater"},{"issue":"2","key":"10.1016\/j.repbio.2026.101209_bib8","doi-asserted-by":"crossref","first-page":"492","DOI":"10.3390\/diagnostics12020492","article-title":"Machine learning-based modeling of ovarian response and the quantitative evaluation of comprehensive impact features","volume":"12","author":"Liu","year":"2022","journal-title":"Diagnostics"},{"issue":"3","key":"10.1016\/j.repbio.2026.101209_bib9","first-page":"477","article-title":"The artificial ovary: the next step in fertility preservation in cancer patients","volume":"18","author":"Varlas","year":"2023","journal-title":"Maedica"},{"issue":"7","key":"10.1016\/j.repbio.2026.101209_bib10","doi-asserted-by":"crossref","first-page":"832","DOI":"10.3390\/bioengineering10070832","article-title":"Bioengineered 3D ovarian models as paramount technology for female health management and reproduction","volume":"10","author":"Del Valle","year":"2023","journal-title":"Bioengineering"},{"issue":"10","key":"10.1016\/j.repbio.2026.101209_bib11","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.3390\/biology14101340","article-title":"Wharton\u2019s jelly hydrogel: an innovative artificial ovary for xenotransplantation of isolated human ovarian follicles","volume":"14","author":"Tajbakhsh","year":"2025","journal-title":"Biology"},{"key":"10.1016\/j.repbio.2026.101209_bib12","doi-asserted-by":"crossref","first-page":"12419","DOI":"10.3390\/ijms232012419","article-title":"Automatic evaluation for bioengineering of human artificial ovary: a model for fertility preservation for prepubertal female patients with a malignant tumor","volume":"23","author":"Wang","year":"2022","journal-title":"Int J Mol Sci"},{"issue":"6","key":"10.1016\/j.repbio.2026.101209_bib13","doi-asserted-by":"crossref","first-page":"543","DOI":"10.3390\/bioengineering11060543","article-title":"Generation of tailored extracellular matrix hydrogels for the study of in vitro folliculogenesis in response to matrisome-dependent biochemical cues","volume":"11","author":"McDowell","year":"2024","journal-title":"Bioengineering"},{"issue":"9","key":"10.1016\/j.repbio.2026.101209_bib14","doi-asserted-by":"crossref","first-page":"3245","DOI":"10.3390\/ijms21093245","article-title":"Human ovarian cortex biobanking: a fascinating resource for fertility preservation in cancer","volume":"21","author":"Silvestris","year":"2020","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.repbio.2026.101209_bib15","first-page":"444","article-title":"From isolation of human ovarian follicles to the artificial ovary: tips and tricks","volume":"70","author":"Chiti","year":"2018","journal-title":"Minerva Ginecol"},{"key":"10.1016\/j.repbio.2026.101209_bib16","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1039\/D5BM01010A","article-title":"A proof-of-concept study on an injectable artificial ovary using a xenogeneic ECM for fertility restoration","volume":"13","author":"Yang","year":"2025","journal-title":"Biomater Sci"},{"key":"10.1016\/j.repbio.2026.101209_bib17","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1002\/term.2870","article-title":"A new possibility in fertility preservation: the artificial ovary","volume":"13","author":"Cho","year":"2019","journal-title":"J Tissue Eng Regen Med"},{"issue":"8","key":"10.1016\/j.repbio.2026.101209_bib18","first-page":"1056","article-title":"A Bioengineered In Situ Ovary (ISO) supports follicle delivery and establishment via ovarian-specific ECM hydrogels","volume":"17","author":"Buckenmeyer","year":"2023","journal-title":"J Tissue Eng Regen Med"},{"issue":"5","key":"10.1016\/j.repbio.2026.101209_bib19","first-page":"479","article-title":"Current trends on bioengineering approaches for ovarian tissue engineering","volume":"29","author":"Almeida","year":"2023","journal-title":"Tissue Eng Part B Rev"},{"key":"10.1016\/j.repbio.2026.101209_bib20","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1186\/s12958-024-01266-y","article-title":"Bioengineered 3D ovarian model for long-term multiple development of preantral follicles: bridging the gap for poly(\u03b5-Caprolactone) (PCL)-based scaffold reproductive applications","volume":"22","author":"Di Berardino","year":"2024","journal-title":"Reprod Biol Endocrinol"},{"key":"10.1016\/j.repbio.2026.101209_bib21","first-page":"98","article-title":"Decellularized extracellular matrix biomaterials for regenerative therapies: advances, challenges and clinical prospects","volume":"32","author":"Golebiowska","year":"2024","journal-title":"Bioact Mater"},{"key":"10.1016\/j.repbio.2026.101209_bib22","article-title":"Extracellular matrix-derived scaffolds in constructing artificial ovaries: preclinical investigations and design considerations","volume":"11","author":"Wu","year":"2023","journal-title":"Front Bioeng Biotechnol"},{"issue":"1","key":"10.1016\/j.repbio.2026.101209_bib23","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1038\/s44334-024-00005-w","article-title":"Multi-Material Vat Photopolymerization 3D Printing: A Review of Mechanisms and Applications","volume":"1","author":"Subedi","year":"2024","journal-title":"npj Adv Manuf"},{"issue":"3","key":"10.1016\/j.repbio.2026.101209_bib24","first-page":"267","article-title":"Biomechanical properties of ovarian tissue and their impact on folliculogenesis initiation","volume":"61","author":"Vasse","year":"2025","journal-title":"Reprod Biomed Online"},{"issue":"12","key":"10.1016\/j.repbio.2026.101209_bib25","doi-asserted-by":"crossref","first-page":"5545","DOI":"10.3390\/ijms26125545","article-title":"Construction and bioengineering of human bioprosthetic ovaries","volume":"26","author":"Cao","year":"2025","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.repbio.2026.101209_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.matdes.2019.108216","article-title":"Nanofibrous Wharton\u2019s jelly scaffold in combination with adipose-derived stem cells for cartilage engineering","volume":"186","author":"Lin","year":"2020","journal-title":"Mater Des"},{"issue":". 1","key":"10.1016\/j.repbio.2026.101209_bib27","article-title":"Roles of Follicle-Stimulating Hormone in Preantral Folliculogenesis of Domestic Animals: What Can We Learn from Model Species and Where Do We Go from Here?","volume":"17","author":"Morton","year":"2023","journal-title":"Animal"},{"issue":"1","key":"10.1016\/j.repbio.2026.101209_bib28","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1186\/s12903-024-04266-x","article-title":"Influence of extracellular matrix scaffolds on histological outcomes of regenerative endodontics in experimental animal models: a systematic review","volume":"24","author":"Elnawam","year":"2024","journal-title":"BMC Oral Health"},{"key":"10.1016\/j.repbio.2026.101209_bib29","series-title":"Biosensors: Developments, Challenges and Perspectives","first-page":"303","article-title":"Artificial Intelligence-Based Quality Control in 3D Bioprinting","author":"Kathirvel","year":"2024"},{"key":"10.1016\/j.repbio.2026.101209_bib30","doi-asserted-by":"crossref","DOI":"10.1177\/1179558119848007","article-title":"Female Fertility Preservation through Stem Cell-Based Ovarian Tissue Reconstitution In Vitro and Ovarian Regeneration In Vivo","volume":"13","author":"Akahori","year":"2019","journal-title":"Clin Med Insights Reprod Health"},{"issue":". 1","key":"10.1016\/j.repbio.2026.101209_bib31","doi-asserted-by":"crossref","first-page":"43","DOI":"10.3109\/09513590.2014.945789","article-title":"Autotransplantation of cryopreserved ovarian tissue\u2014an effective method of fertility preservation in cancer patients","volume":"30","author":"Gamzatova","year":"2014","journal-title":"Gynecol Endocrinol"},{"key":"10.1016\/j.repbio.2026.101209_bib32","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/978-1-0716-1246-0_9","article-title":"Creation of a bioengineered ovary: isolation of female germline stem cells for the repopulation of a decellularized ovarian bioscaffold","volume":"2273","author":"Pennarossa","year":"2021","journal-title":"Methods Mol Biol"},{"issue":"8","key":"10.1016\/j.repbio.2026.101209_bib33","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1093\/humrep\/dez077","article-title":"Initial steps in reconstruction of the human ovary: survival of pre-antral stage follicles in a decellularized human ovarian scaffold","volume":"34","author":"Pors","year":"2019","journal-title":"Hum Reprod"},{"issue":"3","key":"10.1016\/j.repbio.2026.101209_bib34","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1089\/ten.teb.2022.0171","article-title":"Current Trends on Bioengineering Approaches for Ovarian Microenvironment Reconstruction","volume":"29","author":"Almeida","year":"2023","journal-title":"Tissue Eng Part B Rev"},{"key":"10.1016\/j.repbio.2026.101209_bib35","series-title":"Principles of Tissue Engineering","first-page":"1391","article-title":"Three-Dimensional Bioprinting for Tissue Engineering","author":"Huh","year":"2020"},{"key":"10.1016\/j.repbio.2026.101209_bib36","article-title":"Initiation of puberty in mice following decellularized ovary scaffold transplantation","volume":"8","author":"Laronda","year":"2017","journal-title":"Nat Commun"},{"key":"10.1016\/j.repbio.2026.101209_bib37","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.ejogrb.2021.01.014","article-title":"vitro activation of cryopreserved ovarian tissue: A single-arm meta-analysis and systematic review","volume":"258","author":"Wang","year":"2021","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.repbio.2026.101209_bib38","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1071\/RD17411","article-title":"Preantral follicle culture and oocyte quality","volume":"30","author":"Heiligentag","year":"2017","journal-title":"Reprod Fertil Dev"},{"issue":"3","key":"10.1016\/j.repbio.2026.101209_bib39","first-page":"400","article-title":"Fresh and cryopreserved ovarian tissue transplantation for preserving reproductive and endocrine function: a systematic review and individual patient data meta-analysis","volume":"30","author":"D\u00edaz-Garc\u00eda","year":"2024","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.repbio.2026.101209_bib40","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1093\/humupd\/dmac003","article-title":"Fresh and cryopreserved ovarian tissue transplantation for preserving reproductive and endocrine function: a systematic review and individual patient data meta-analysis","volume":"28","author":"Khattak","year":"2022","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.repbio.2026.101209_bib41","article-title":"A systematic review of ovarian tissue transplantation outcomes: restored endocrine function and fertility potential","volume":"13","author":"Masciangelo","year":"2022","journal-title":"Front Endocrinol"},{"issue":"1","key":"10.1016\/j.repbio.2026.101209_bib42","first-page":"1","article-title":"Ovarian tissue cryopreservation and transplantation in patients with cancer: a review of clinical outcomes and endocrine function recovery","volume":"50","author":"Park","year":"2023","journal-title":"Clin Exp Reprod Med"},{"issue":"10","key":"10.1016\/j.repbio.2026.101209_bib43","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.3390\/biology14101340","article-title":"Wharton\u2019s jelly hydrogel: an innovative artificial ovary for xenotransplantation of isolated human ovarian follicles","volume":"14","author":"Tajbakhsh","year":"2025","journal-title":"Biology"},{"issue":"4","key":"10.1016\/j.repbio.2026.101209_bib44","first-page":"1010","article-title":"A proof-of-concept injectable artificial ovary using xenogeneic extracellular matrix hydrogels to restore ovarian function","volume":"13","author":"Yang","year":"2025","journal-title":"Biomater Sci"},{"issue":"5","key":"10.1016\/j.repbio.2026.101209_bib45","article-title":"Encapsulated allografts preclude host sensitization and promote ovarian endocrine function in ovariectomized young rhesus monkeys and sensitized mice","volume":"10","author":"Day","year":"2023","journal-title":"Bioengineering (Basel)."},{"key":"10.1016\/j.repbio.2026.101209_bib46","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2024.1443494","article-title":"Ovarian tissue autotransplantation improves longevity in mice","volume":"15","author":"Ruhliada","year":"2024","journal-title":"Front Physiol"},{"issue":"1","key":"10.1016\/j.repbio.2026.101209_bib47","first-page":"1","article-title":"Gene Editing: Developments, Ethical Considerations, and Future Directions","volume":"15","author":"Parikh","year":"2025","journal-title":"J Community Hosp Intern Med Perspect"},{"issue":"4","key":"10.1016\/j.repbio.2026.101209_bib48","first-page":"436","article-title":"Risk of transplanting malignant cells in cryopreserved ovarian tissue","volume":"70","author":"Dolmans","year":"2018","journal-title":"Minerva Ginecol"},{"key":"10.1016\/j.repbio.2026.101209_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.jconrel.2025.02.057","article-title":"J.H. Automated manufacturing of cell therapies","volume":"381","author":"Melocchi","year":"2025","journal-title":"J Control Release"},{"issue":"8","key":"10.1016\/j.repbio.2026.101209_bib50","doi-asserted-by":"crossref","first-page":"1610","DOI":"10.1093\/humrep\/deu132","article-title":"ESHRE task force on ethics and law 22: preimplantation genetic diagnosis","volume":"29","author":"De Wert","year":"2014","journal-title":"Hum Reprod"},{"key":"10.1016\/j.repbio.2026.101209_bib51","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/s42242-020-00082-8","article-title":"Bioengineering models of female reproduction","volume":"3","author":"Zubizarreta","year":"2020","journal-title":"BioDes Manuf"},{"key":"10.1016\/j.repbio.2026.101209_bib52","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-023-41954-0","article-title":"Regulation of Follicular Activation Signaling Pathways by in Vitro Inhibition of YAP\/TAZ Activity in Mouse Ovaries","volume":"13","author":"Devos","year":"2023","journal-title":"Sci Rep"},{"key":"10.1016\/j.repbio.2026.101209_bib53","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/s12958-020-00630-y","article-title":"Decellularization and Recellularization of the Ovary for Bioengineering Applications: Studies in the Mouse","volume":"18","author":"Alshaikh","year":"2020","journal-title":"Reprod Biol Endocrinol"},{"issue":"3","key":"10.1016\/j.repbio.2026.101209_bib54","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1007\/s00404-025-08091-7","article-title":"Enhancement of Angiogenesis and Follicular Survival Using Growth Factors During Ovarian Tissue Transplantation: A Systematic Review","volume":"312","author":"Zhang","year":"2025","journal-title":"Arch Gynecol Obstet"},{"key":"10.1016\/j.repbio.2026.101209_bib55","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2023.1177443","article-title":"Prospects for Fertility Preservation: The Ovarian Organ Function Reconstruction Techniques for Oogenesis, Growth and Maturation In Vitro","volume":"14","author":"Hu","year":"2023","journal-title":"Front Physiol"},{"issue":"2","key":"10.1016\/j.repbio.2026.101209_bib56","doi-asserted-by":"crossref","DOI":"10.1093\/hropen\/hoad014","article-title":"Extracellular matrix-derived scaffolds in constructing artificial ovaries: current status and future perspectives","volume":"2023","author":"Wu","year":"2023","journal-title":"Hum Reprod Open"},{"issue":"7","key":"10.1016\/j.repbio.2026.101209_bib57","doi-asserted-by":"crossref","DOI":"10.1111\/cts.13863","article-title":"Strategies for developing 3D printed ovarian model for restoring fertility","volume":"17","author":"Nair","year":"2024","journal-title":"Clin Transl Sci"},{"key":"10.1016\/j.repbio.2026.101209_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.bpobgyn.2025.102641","article-title":"Engineering strategies and challenges in building the follicular microenvironment for a bioprosthetic ovary","volume":"102","author":"Saunders","year":"2025","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"10.1016\/j.repbio.2026.101209_bib59","doi-asserted-by":"crossref","first-page":"22631","DOI":"10.1038\/s41598-025-06998-4","article-title":"Development and validation of machine learning models for predicting blastocyst yield in IVF cycles","volume":"15","author":"Huo","year":"2025","journal-title":"Sci Rep"},{"key":"10.1016\/j.repbio.2026.101209_bib60","article-title":"Influence of Ovarian Stromal Cells on Human Ovarian Follicle Development In Vitro","volume":"1","author":"Grubliauskait\u0117","year":"2024","journal-title":"Hum. Reprod. Open"},{"issue":"1","key":"10.1016\/j.repbio.2026.101209_bib61","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1186\/s13048-025-01673-8","article-title":"Generation of Healthy Bovine Ovarian Organoids: A Proof-of-Concept Derivation Technique","volume":"18","author":"G\u00f3mez-\u00c1lvarez","year":"2025","journal-title":"J Ovarian Res"},{"key":"10.1016\/j.repbio.2026.101209_sbref62","doi-asserted-by":"crossref","first-page":"4122","DOI":"10.1186\/s13287-024-04122-3","article-title":"Research Advances in the Construction of Stem Cell-Derived Ovarian Organoids","volume":"15","author":"Zhang","year":"2024","journal-title":"Stem Cell Res Ther"},{"issue":"1","key":"10.1016\/j.repbio.2026.101209_sbref63","first-page":"1","article-title":"Regeneration of the female reproductive system using 3D bioprinting: current status and future prospects","volume":"21","author":"Malhotra","year":"2024","journal-title":"Expert Rev Med Devices"},{"key":"10.1016\/j.repbio.2026.101209_bib63","article-title":"Directed Differentiation of Human iPSCs to Functional Ovarian Granulosa-Like Cells via Transcription Factor Overexpression","volume":"12","author":"Pierson Smela","year":"2023","journal-title":"eLife"},{"issue":"2","key":"10.1016\/j.repbio.2026.101209_bib64","doi-asserted-by":"crossref","first-page":"924","DOI":"10.3390\/ijms24020924","article-title":"MitoQ protects ovarian organoids against oxidative stress during oogenesis and folliculogenesis in vitro","volume":"24","author":"Wang","year":"2023","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.repbio.2026.101209_bib65","doi-asserted-by":"crossref","first-page":"2323","DOI":"10.2217\/fon-2016-0202","article-title":"The artificial ovary: current status and future perspectives","volume":"12","author":"Amorim","year":"2016","journal-title":"Future Oncol"},{"key":"10.1016\/j.repbio.2026.101209_bib66","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2024.1332673","article-title":"Ovarian tissue transplantation: 10 years of experience at the bologna university","volume":"15","author":"Fabbri","year":"2024","journal-title":"Front Endocrinol"}],"container-title":["Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1642431X26000318?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1642431X26000318?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T11:32:38Z","timestamp":1785843158000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1642431X26000318"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":67,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["S1642431X26000318"],"URL":"https:\/\/doi.org\/10.1016\/j.repbio.2026.101209","relation":{},"ISSN":["1642-431X"],"issn-type":[{"value":"1642-431X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Artificial ovary systems for fertility preservation: Current advances, bioengineering strategies, and translational perspectives","name":"articletitle","label":"Article Title"},{"value":"Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.repbio.2026.101209","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Society for Biology of Reproduction & the Institute of Animal Reproduction and Food Research of Polish Academy of Sciences in Olsztyn. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"101209"}}