{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T18:53:07Z","timestamp":1760122387131,"version":"build-2065373602"},"reference-count":10,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,8,29]],"date-time":"2018-08-29T00:00:00Z","timestamp":1535500800000},"content-version":"vor","delay-in-days":1397,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Revista Portuguesa de Cardiologia"],"published-print":{"date-parts":[[2014,11]]},"DOI":"10.1016\/j.repc.2014.06.005","type":"journal-article","created":{"date-parts":[[2014,11,4]],"date-time":"2014-11-04T21:24:31Z","timestamp":1415136271000},"page":"737.e1-737.e5","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Holt-Oram syndrome: A case report"],"prefix":"10.1016","volume":"33","author":[{"given":"Joana","family":"Chin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salom\u00e9","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Camacho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernardo","family":"Pessoa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dina","family":"Bento","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9","family":"Amado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Il\u00eddio","family":"de Jesus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.repc.2014.06.005_bib0005","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1136\/hrt.22.2.236","article-title":"Familial heart disease with skeletal malformations","volume":"22","author":"Holt","year":"1960","journal-title":"Br Heart J"},{"key":"10.1016\/j.repc.2014.06.005_bib0010","first-page":"432","article-title":"Holt-Oram syndrome revisited. Two patients in the same family","volume":"73","author":"Filho","year":"1999","journal-title":"Arq Bras Cardiol"},{"key":"10.1016\/j.repc.2014.06.005_bib0015","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1093\/bja\/80.6.856","volume":"80","author":"Shono","year":"1998","journal-title":"Br J Anesth"},{"issue":"6","key":"10.1016\/j.repc.2014.06.005_bib0020","doi-asserted-by":"crossref","first-page":"2919","DOI":"10.1073\/pnas.96.6.2919","article-title":"Different TBX5 interactions in heart and limb defined by Holt-Oram syndrome mutations","volume":"96","author":"Basson","year":"1999","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.repc.2014.06.005_bib0025","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1097\/00008480-200212000-00008","article-title":"Current advances in Holt-Oram syndrome","volume":"14","author":"Huang","year":"2002","journal-title":"Curr Opin Pediatr"},{"key":"10.1016\/j.repc.2014.06.005_bib0030","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1056\/NEJM199403313301302","article-title":"The clinical and genetic spectrum of the Holt-Oram syndrome (heart-hand syndrome)","volume":"330","author":"Basson","year":"1994","journal-title":"N Engl J Med"},{"issue":"2","key":"10.1016\/j.repc.2014.06.005_bib0035","first-page":"87","article-title":"A case report on Holt-Oram syndrome (heart-hand)","volume":"7","author":"Nourzad","year":"2011","journal-title":"ARYA Atherosclerosis"},{"key":"10.1016\/j.repc.2014.06.005_bib0040","doi-asserted-by":"crossref","first-page":"e3","DOI":"10.5830\/CVJA-2011-017","article-title":"Rare cardiac defect in Holt-Oram syndrome","volume":"23","author":"Sinha","year":"2012","journal-title":"Cardiovasc J Afr"},{"key":"10.1016\/j.repc.2014.06.005_bib0045","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1203\/01.PDR.0000182593.95441.64","article-title":"TBX5 genetic testing validates strict clinical criteria for Holt-Oram syndrome","volume":"58","author":"McDermott","year":"2005","journal-title":"Pediatric Res"},{"key":"10.1016\/j.repc.2014.06.005_bib0050","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1161\/CIRCRESAHA.108.178079","article-title":"Holt-Oram syndrome and atrial fibrillation: opening the (T)-box","volume":"102","author":"Cerbai","year":"2008","journal-title":"Circ Res"}],"container-title":["Revista Portuguesa de Cardiologia"],"original-title":[],"language":"pt","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0870255114002571?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0870255114002571?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:02:24Z","timestamp":1760108544000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0870255114002571"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11]]},"references-count":10,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["S0870255114002571"],"URL":"https:\/\/doi.org\/10.1016\/j.repc.2014.06.005","relation":{},"ISSN":["0870-2551"],"issn-type":[{"type":"print","value":"0870-2551"}],"subject":[],"published":{"date-parts":[[2014,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Holt-Oram syndrome: A case report","name":"articletitle","label":"Article Title"},{"value":"Revista Portuguesa de Cardiologia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.repc.2014.06.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Sociedade Portuguesa de Cardiologia. Published by Elsevier Espa\u00f1a, S.L. All rights reserved.","name":"copyright","label":"Copyright"}]}}