{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T08:41:15Z","timestamp":1775724075011,"version":"3.50.1"},"reference-count":118,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,12,8]],"date-time":"2018-12-08T00:00:00Z","timestamp":1544227200000},"content-version":"vor","delay-in-days":433,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Revista Portuguesa de Cardiologia"],"published-print":{"date-parts":[[2017,10]]},"DOI":"10.1016\/j.repc.2017.01.007","type":"journal-article","created":{"date-parts":[[2017,10,14]],"date-time":"2017-10-14T19:15:17Z","timestamp":1508008517000},"page":"757-771","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Insights into the background of autonomic medicine"],"prefix":"10.1016","volume":"36","author":[{"given":"S\u00e9rgio","family":"Laranjo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vera","family":"Geraldes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1rio","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel","family":"Rocha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.repc.2017.01.007_bib0595","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S1566-0702(00)00171-5","article-title":"Perspectives on the integrative functions of the \u2018sympatho-adrenomedullary system\u2019","volume":"83","author":"Folkow","year":"2000","journal-title":"Auton Neurosci"},{"key":"10.1016\/j.repc.2017.01.007_bib0600","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1023\/A:1007687911139","article-title":"Allostasis, allostatic load, and the aging nervous system: role of excitatory amino acids and excitotoxicity","volume":"25","author":"McEwen","year":"2000","journal-title":"Neurochem Res"},{"key":"10.1016\/j.repc.2017.01.007_bib0605","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/S0018-506X(02)00024-7","article-title":"The concept of allostasis in biology and biomedicine","volume":"43","author":"McEwen","year":"2003","journal-title":"Horm Behav"},{"key":"10.1016\/j.repc.2017.01.007_bib0610","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1113\/eph8802476","article-title":"Angiotensin AT1 receptor antagonist losartan and the defence reaction in the anaesthetised rat. Effect on the carotid chemoreflex","volume":"88","author":"Rocha","year":"2003","journal-title":"Exp Physiol"},{"key":"10.1016\/j.repc.2017.01.007_bib0615","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1007\/s10286-004-0212-0","article-title":"Effect of stimulation of anterior hypothalamic area on urinary bladder function of the anesthetized rat","volume":"14","author":"Rocha","year":"2004","journal-title":"Clin Auton Res"},{"key":"10.1016\/j.repc.2017.01.007_bib0620","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1152\/physrev.1994.74.2.323","article-title":"Functional organization of central pathways regulating the cardiovascular system","volume":"74","author":"Dampney","year":"1994","journal-title":"Physiol Rev"},{"key":"10.1016\/j.repc.2017.01.007_bib0625","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.repc.2012.01.007","article-title":"Acute electrophysiological modulation of the atria and pulmonary veins: effects of sympathetic and parasympathetic interaction on atrial fibrillation inducibility","volume":"31","author":"Oliveira","year":"2012","journal-title":"Rev Port Cardiol"},{"key":"10.1016\/j.repc.2017.01.007_bib0630","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1113\/expphysiol.2013.074823","article-title":"Chronic depression of hypothalamic paraventricular neuronal activity produces sustained hypotension in hypertensive rats","volume":"99","author":"Geraldes","year":"2014","journal-title":"Exp Physiol"},{"key":"10.1016\/j.repc.2017.01.007_bib0635","first-page":"655","article-title":"Effects of stimulation and blockade of the autonomic nervous system on atrial refractoriness in patients with lone paroxysmal atrial fibrillation","volume":"28","author":"Oliveira","year":"2009","journal-title":"Rev Port Cardiol"},{"key":"10.1016\/j.repc.2017.01.007_bib0640","series-title":"Disorders of the autonomic nervous system","author":"Robertson","year":"1994"},{"key":"10.1016\/j.repc.2017.01.007_bib0645","series-title":"Clinical autonomic disorders","author":"Low","year":"2008"},{"key":"10.1016\/j.repc.2017.01.007_bib0650","series-title":"The autonomic nervous system","author":"Appenzeller","year":"2000"},{"key":"10.1016\/j.repc.2017.01.007_bib0655","series-title":"Integrative action of the autonomic nervous system: neurobiology of homeostasis","author":"J\u00e4nig","year":"2008"},{"key":"10.1016\/j.repc.2017.01.007_bib0660","series-title":"Autonomic failure: a textbook of clinical disorders of the autonomic nervous system","author":"Mathias","year":"2012"},{"key":"10.1016\/j.repc.2017.01.007_bib0665","series-title":"Central regulation of autonomic functions","author":"Loewy","year":"1990"},{"key":"10.1016\/j.repc.2017.01.007_bib0670","series-title":"Integrative action of the autonomic nervous system: neurobiology of homeostasis","author":"J\u00e4nig","year":"2008"},{"key":"10.1016\/j.repc.2017.01.007_bib0675","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.1016\/0016-5085(90)90475-G","article-title":"Role of visceral afferent mechanisms in functional bowel disorders","volume":"99","author":"Mayer","year":"1990","journal-title":"Gastroenterology"},{"key":"10.1016\/j.repc.2017.01.007_bib0680","doi-asserted-by":"crossref","first-page":"2374","DOI":"10.1152\/jn.1998.79.5.2374","article-title":"Convergence properties of solitary tract neurons responsive to cardiac receptor stimulation in the anesthetized cat","volume":"79","author":"Silva-Carvalho","year":"1998","journal-title":"J Neurophysiol"},{"key":"10.1016\/j.repc.2017.01.007_bib0685","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/S0306-4522(99)00040-8","article-title":"Late vagal inhibition in neurons of the ventrolateral medulla oblongata in the rat","volume":"92","author":"Zagon","year":"1999","journal-title":"Neuroscience"},{"key":"10.1016\/j.repc.2017.01.007_bib0690","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/S0006-8993(99)02338-0","article-title":"Activation of cardiac vagal afferents facilitates late vagal inhibition in neurones of the rostral ventrolateral medulla oblongata bilaterally","volume":"854","author":"Zagon","year":"2000","journal-title":"Brain Res"},{"key":"10.1016\/j.repc.2017.01.007_bib0695","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1098\/rstb.1984.0087","article-title":"The origin and possible significance of substance P immunoreactive networks in the prevertebral ganglia and related structures in the guinea-pig","volume":"306","author":"Matthews","year":"1984","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"10.1016\/j.repc.2017.01.007_bib0700","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/978-3-540-79090-7_6","article-title":"Regulation of cardiac afferent excitability in ischemia","author":"Fu","year":"2009","journal-title":"Handb Exp Pharmacol"},{"key":"10.1016\/j.repc.2017.01.007_bib0705","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1111\/j.1445-5994.1990.tb01325.x","article-title":"Cardiovascular reflexes from cardiac sensory receptors","volume":"20","author":"Ludbrook","year":"1990","journal-title":"Aust N Z J Med"},{"key":"10.1016\/j.repc.2017.01.007_bib0710","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0079-6123(08)62757-0","article-title":"Vagal afferent innervation of the gastrointestinal tract","volume":"67","author":"Andrews","year":"1986","journal-title":"Prog Brain Res"},{"key":"10.1016\/j.repc.2017.01.007_bib0715","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1002\/cne.902460107","article-title":"Identification of distinct topographical distributions of lumbar sympathetic and sensory neurons projecting to end organs with different functions in the cat","volume":"246","author":"J\u00e4nig","year":"1986","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.repc.2017.01.007_bib0720","series-title":"Human physiology: from cells to systems","author":"Sherwood","year":"2010"},{"key":"10.1016\/j.repc.2017.01.007_bib0725","series-title":"The enteric nervous system","author":"Furness","year":"1987"},{"key":"10.1016\/j.repc.2017.01.007_bib0730","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1002\/ar.a.10064","article-title":"Morphologies and projections of defined classes of neurons in the submucosa of the guinea-pig small intestine","volume":"272","author":"Furness","year":"2003","journal-title":"Anat Rec A Discov Mol Cell Evol Biol"},{"key":"10.1016\/j.repc.2017.01.007_bib0735","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.autneu.2006.05.003","article-title":"The organisation of the autonomic nervous system: peripheral connections","volume":"130","author":"Furness","year":"2006","journal-title":"Auton Neurosci"},{"key":"10.1016\/j.repc.2017.01.007_bib0740","series-title":"Human physiology: the mechanisms of body function","author":"Vander","year":"2001"},{"key":"10.1016\/j.repc.2017.01.007_bib0745","series-title":"Basic neurosciences with clinical applications","author":"Benarroch","year":"2006"},{"key":"10.1016\/j.repc.2017.01.007_bib0750","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/0306-4522(94)00595-V","article-title":"Visualization and immunohistochemical characterization of sympathetic and parasympathetic neurons in the male rat major pelvic ganglion","volume":"66","author":"Keast","year":"1995","journal-title":"Neuroscience"},{"key":"10.1016\/j.repc.2017.01.007_bib0755","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0074-7696(08)61778-7","article-title":"Unusual autonomic ganglia: connections, chemistry, and plasticity of pelvic ganglia","volume":"193","author":"Keast","year":"1999","journal-title":"Int Rev Cytol"},{"key":"10.1016\/j.repc.2017.01.007_bib0760","series-title":"Principles of neural science","author":"Kandel","year":"2000"},{"key":"10.1016\/j.repc.2017.01.007_bib0765","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1159\/000025569","article-title":"Neural control of coronary blood flow","volume":"35","author":"Feigl","year":"1998","journal-title":"J Vasc Res"},{"issue":"Pt 3","key":"10.1016\/j.repc.2017.01.007_bib0770","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1111\/j.1469-7793.1998.869bs.x","article-title":"Activity of C fibre cardiac vagal efferents in anaesthetized cats and rats","volume":"507","author":"Jones","year":"1998","journal-title":"J Physiol"},{"key":"10.1016\/j.repc.2017.01.007_bib0775","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1002\/(SICI)1096-9861(19990726)410:2<320::AID-CNE12>3.0.CO;2-5","article-title":"Projections of the dorsal motor nucleus of the vagus to cardiac ganglia of rat atria: an anterograde tracing study","volume":"410","author":"Cheng","year":"1999","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.repc.2017.01.007_bib0780","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1002\/cne.903270408","article-title":"Localization of cardiac vagal preganglionic motoneurones in the rat: immunocytochemical evidence of synaptic inputs containing 5-hydroxytryptamine","volume":"327","author":"Izzo","year":"1993","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.repc.2017.01.007_bib0785","series-title":"Primer on the autonomic nervous system","year":"2012"},{"issue":"Pt 3","key":"10.1016\/j.repc.2017.01.007_bib0790","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1113\/jphysiol.1995.sp020915","article-title":"Hypothalamic modulation of the arterial chemoreceptor reflex in the anaesthetized cat: role of the nucleus tractus solitarii","volume":"487","author":"Silva-Carvalho","year":"1995","journal-title":"J Physiol"},{"key":"10.1016\/j.repc.2017.01.007_bib0795","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1161\/01.HYP.38.3.549","article-title":"Role of the medulla oblongata in hypertension","volume":"38","author":"Colombari","year":"2001","journal-title":"Hypertension"},{"key":"10.1016\/j.repc.2017.01.007_bib0800","series-title":"Physiology","author":"Berne","year":"2001"},{"key":"10.1016\/j.repc.2017.01.007_bib0805","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1590\/S0100-879X1997000400015","article-title":"Autonomic processing of the cardiovascular reflexes in the nucleus tractus solitarii","volume":"30","author":"Machado","year":"1997","journal-title":"Braz J Med Biol Res"},{"issue":"Suppl. A","key":"10.1016\/j.repc.2017.01.007_bib0810","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1093\/eurheartj\/13.suppl_A.2","article-title":"Central control of blood pressure","volume":"13","author":"Chalmers","year":"1992","journal-title":"Eur Heart J"},{"key":"10.1016\/j.repc.2017.01.007_bib0815","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1152\/physrev.1994.74.3.543","article-title":"Peripheral chemoreceptors and cardiovascular regulation","volume":"74","author":"Marshall","year":"1994","journal-title":"Physiol Rev"},{"key":"10.1016\/j.repc.2017.01.007_bib0820","doi-asserted-by":"crossref","first-page":"III31","DOI":"10.1161\/01.HYP.18.5_Suppl.III31","article-title":"Role of the baroreceptor reflexes in circulatory control, with particular reference to hypertension","volume":"18","author":"Sleight","year":"1991","journal-title":"Hypertension"},{"key":"10.1016\/j.repc.2017.01.007_bib0825","series-title":"Central regulation of autonomic functions","first-page":"168","article-title":"The central nervous organization of reflex circulatory control","author":"Spyer","year":"1990"},{"key":"10.1016\/j.repc.2017.01.007_bib0830","first-page":"1049","article-title":"Contribution of the cardiopulmonary reflex to the cardiovascular regulation in normal and pathophysiological states","volume":"27","author":"Vasquez","year":"1994","journal-title":"Braz J Med Biol Res"},{"key":"10.1016\/j.repc.2017.01.007_bib0835","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/0022-2828(89)90738-4","article-title":"Stretch-induced centrifugal movement of atrial specific granules\u2013a preparatory step in atrial natriuretic peptide secretion","volume":"21","author":"Agnoletti","year":"1989","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.repc.2017.01.007_bib0840","series-title":"Fisiolog\u00eda humana","author":"Tresguerres","year":"2005"},{"key":"10.1016\/j.repc.2017.01.007_bib0845","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/0002-9149(79)90220-0","article-title":"Control of blood pressure by carotid sinus baroreceptors in human beings","volume":"44","author":"Mancia","year":"1979","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.repc.2017.01.007_bib0850","first-page":"H680","article-title":"Hemodynamic fluctuations and baroreflex sensitivity in humans: a beat-to-beat model","volume":"253","author":"deBoer","year":"1987","journal-title":"Am J Physiol"},{"key":"10.1016\/j.repc.2017.01.007_bib0855","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1113\/jphysiol.1984.sp015072","article-title":"The central projections of carotid baroreceptors and chemoreceptors in the cat: a neurophysiological study","volume":"347","author":"Donoghue","year":"1984","journal-title":"J Physiol"},{"key":"10.1016\/j.repc.2017.01.007_bib0860","first-page":"173","article-title":"Processing of afferent inputs in cardiovascular control","volume":"6","author":"Spyer","year":"1984","journal-title":"Clin Exp Hypertens A"},{"key":"10.1016\/j.repc.2017.01.007_bib0865","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1161\/01.RES.51.5.624","article-title":"Carotid sinus baroreceptor reflex control of respiration","volume":"51","author":"Brunner","year":"1982","journal-title":"Circ Res"},{"key":"10.1016\/j.repc.2017.01.007_bib0870","first-page":"R51","article-title":"Vasopressin responses to unloading arterial baroreceptors during cardiac nerve blockade in conscious dogs","volume":"262","author":"O\u2019Donnell","year":"1992","journal-title":"Am J Physiol"},{"key":"10.1016\/j.repc.2017.01.007_bib0875","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0304-3940(96)13115-3","article-title":"Neurons in the caudal ventrolateral medulla projecting to the paraventricular hypothalamic nucleus receive synaptic inputs from the nucleus of the solitary tract: a light and electron microscopic double-labeling study in the rat","volume":"218","author":"Kawano","year":"1996","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.repc.2017.01.007_bib0880","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0304-3940(85)90162-4","article-title":"Excitation of neuronal function in rabbit caudal ventrolateral medulla elevates plasma vasopressin","volume":"58","author":"Blessing","year":"1985","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.repc.2017.01.007_bib0885","first-page":"R671","article-title":"Osmoregulation and control of vasopressin secretion in healthy humans","volume":"253","author":"Baylis","year":"1987","journal-title":"Am J Physiol"},{"key":"10.1016\/j.repc.2017.01.007_bib0890","first-page":"R1843","article-title":"Arterial baroreceptors control blood pressure and vasopressin responses to hemorrhage in conscious dogs","volume":"275","author":"Thrasher","year":"1998","journal-title":"Am J Physiol"},{"key":"10.1016\/j.repc.2017.01.007_bib0895","first-page":"R1187","article-title":"Vasopressin-induced suppression of renal sympathetic outflow depends on the number of baroafferent inputs in rabbits","volume":"263","author":"Nishida","year":"1992","journal-title":"Am J Physiol"},{"key":"10.1016\/j.repc.2017.01.007_bib0900","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1111\/j.1440-1681.2005.04205.x","article-title":"Long-term regulation of arterial blood pressure by hypothalamic nuclei: some critical questions","volume":"32","author":"Dampney","year":"2005","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"10.1016\/j.repc.2017.01.007_bib0905","series-title":"Peripheral arterial chemoreceptors and respiratory-cardiovascular integration","author":"Burgh Daly","year":"1997"},{"key":"10.1016\/j.repc.2017.01.007_bib0910","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1002\/j.2040-4603.2012.tb00403.x","article-title":"Central chemoreceptors: locations and functions","volume":"2","author":"Nattie","year":"2012","journal-title":"Compr Physiol"},{"key":"10.1016\/j.repc.2017.01.007_bib0915","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1113\/jphysiol.1982.sp014040","article-title":"Identification and brain-stem projections of aortic baroreceptor afferent neurones in nodose ganglia of cats and rabbits","volume":"322","author":"Donoghue","year":"1982","journal-title":"J Physiol"},{"key":"10.1016\/j.repc.2017.01.007_bib0920","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1113\/jphysiol.1930.sp002648","article-title":"Sinus caroticus and respiratory reflexes: I. Cerebral blood flow and respiration. Adrenaline apnoea","volume":"69","author":"Heymans","year":"1930","journal-title":"J Physiol"},{"key":"10.1016\/j.repc.2017.01.007_bib0925","first-page":"R677","article-title":"Carotid chemoreceptors influence arterial pressure in intact and aortic-denervated rats","volume":"262","author":"Franchini","year":"1992","journal-title":"Am J Physiol"},{"key":"10.1016\/j.repc.2017.01.007_bib0930","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1152\/physrev.1992.72.3.789","article-title":"Involvement of neurotransmitters in the nucleus tractus solitarii in cardiovascular regulation","volume":"72","author":"van Giersbergen","year":"1992","journal-title":"Physiol Rev"},{"key":"10.1016\/j.repc.2017.01.007_bib0935","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/0165-1838(88)90018-5","article-title":"Effects of volume loading on paraventriculo-spinal neurones in the rat","volume":"25","author":"Lovick","year":"1988","journal-title":"J Auton Nerv Syst"},{"key":"10.1016\/j.repc.2017.01.007_bib0940","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1016\/S0306-4522(97)00232-7","article-title":"Distribution of activated neurons in the rabbit brain following a volume load","volume":"81","author":"Badoer","year":"1997","journal-title":"Neuroscience"},{"key":"10.1016\/j.repc.2017.01.007_bib0945","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1113\/jphysiol.1915.sp001736","article-title":"The influence of venous filling upon the rate of the heart","volume":"50","author":"Bainbridge","year":"1915","journal-title":"J Physiol"},{"key":"10.1016\/j.repc.2017.01.007_bib0950","series-title":"Untersuchungen aus dem physiologischen Laboratorium in W\u00fcrzburg","author":"Bezold","year":"1867"},{"key":"10.1016\/j.repc.2017.01.007_bib0955","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1113\/expphysiol.2007.038026","article-title":"Wavelet analysis of autonomic outflow of normal subjects on head-up tilt, cold pressor test, Valsalva manoeuvre and deep breathing","volume":"92","author":"Ducla-Soares","year":"2007","journal-title":"Exp Physiol"},{"key":"10.1016\/j.repc.2017.01.007_bib0960","first-page":"435","article-title":"The Valsalva maneuver revisited by wavelets","volume":"27","author":"Xavier","year":"2008","journal-title":"Rev Port Cardiol"},{"key":"10.1016\/j.repc.2017.01.007_bib0965","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1046\/j.1365-201X.2003.01089.x","article-title":"Sympathetic nerve activity and neurotransmitter release in humans: translation from pathophysiology into clinical practice","volume":"177","author":"Esler","year":"2003","journal-title":"Acta Physiol Scand"},{"key":"10.1016\/j.repc.2017.01.007_bib0970","first-page":"611","article-title":"The sympathetic nervous system through the ages: from Thomas Willis to resistant hypertension","volume":"96","author":"Esler","year":"2011","journal-title":"Exp Physiol"},{"key":"10.1016\/j.repc.2017.01.007_bib0975","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1161\/01.HYP.5.4.552","article-title":"Relationship between plasma norepinephrine and sympathetic neural activity","volume":"5","author":"Goldstein","year":"1983","journal-title":"Hypertension"},{"key":"10.1016\/j.repc.2017.01.007_bib0980","first-page":"II36","article-title":"What do plasma and urinary measures of catecholamines tell us about human response to stressors?","volume":"83","author":"Dimsdale","year":"1991","journal-title":"Circulation"},{"key":"10.1016\/j.repc.2017.01.007_bib0985","doi-asserted-by":"crossref","first-page":"11","DOI":"10.5114\/aoms.2010.13500","article-title":"Methods of evaluation of autonomic nervous system function","volume":"6","author":"Zygmunt","year":"2010","journal-title":"Arch Med Sci"},{"issue":"Suppl. 11","key":"10.1016\/j.repc.2017.01.007_bib0990","first-page":"79","article-title":"Why study sympathetic nervous system?","volume":"57","author":"Sinski","year":"2006","journal-title":"J Physiol Pharmacol"},{"issue":"Suppl. 3","key":"10.1016\/j.repc.2017.01.007_bib0995","article-title":"Autonomic diseases: clinical features and laboratory evaluation","volume":"74","author":"Mathias","year":"2003","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.repc.2017.01.007_bib1000","doi-asserted-by":"crossref","first-page":"1979","DOI":"10.1097\/00004872-199816121-00019","article-title":"Role of the sympathetic nervous system in human hypertension","volume":"16","author":"Grassi","year":"1998","journal-title":"J Hypertens"},{"key":"10.1016\/j.repc.2017.01.007_bib1005","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1097\/00004872-199917060-00001","article-title":"How to assess sympathetic activity in humans","volume":"17","author":"Grassi","year":"1999","journal-title":"J Hypertens"},{"key":"10.1016\/j.repc.2017.01.007_bib1010","doi-asserted-by":"crossref","first-page":"H1407","DOI":"10.1152\/ajpheart.00173.2013","article-title":"Recording sympathetic nerve activity chronically in rats: surgery techniques, assessment of nerve activity, and quantification","volume":"305","author":"Stocker","year":"2013","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.repc.2017.01.007_bib1015","first-page":"313","article-title":"A new method for evaluating the baroreflex role by a joint pattern analysis of pulse interval and systolic blood pressure series","volume":"23","author":"Di Rienzo","year":"1983","journal-title":"Med Biol Eng Comput"},{"key":"10.1016\/j.repc.2017.01.007_bib1020","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0010-4825(98)00005-5","article-title":"A software package for non-invasive, real-time beat-to-beat monitoring of stroke volume, blood pressure, total peripheral resistance and for assessment of autonomic function","volume":"28","author":"Gratze","year":"1998","journal-title":"Comput Biol Med"},{"key":"10.1016\/j.repc.2017.01.007_bib1025","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1126\/science.6166045","article-title":"Power spectrum analysis of heart rate fluctuation: a quantitative probe of beat-to-beat cardiovascular control","volume":"213","author":"Akselrod","year":"1981","journal-title":"Science"},{"key":"10.1016\/j.repc.2017.01.007_bib1030","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1378\/chest.83.2_Supplement.317","article-title":"Blood pressure variability at normal and high blood pressure","volume":"83","author":"Mancia","year":"1983","journal-title":"Chest"},{"key":"10.1016\/j.repc.2017.01.007_bib1035","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1161\/01.HYP.8.2.147","article-title":"Arterial baroreflexes and blood pressure and heart rate variabilities in humans","volume":"8","author":"Mancia","year":"1986","journal-title":"Hypertension"},{"key":"10.1016\/j.repc.2017.01.007_bib1040","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1056\/NEJM199302043280511","article-title":"Autonomic modulation of the cardiovascular system during sleep","volume":"328","author":"Mancia","year":"1993","journal-title":"N Engl J Med"},{"key":"10.1016\/j.repc.2017.01.007_bib1045","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1016\/0735-1097(89)90408-7","article-title":"Beat to beat variability in cardiovascular variables: noise or music?","volume":"14","author":"Appel","year":"1989","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.repc.2017.01.007_bib1050","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/0165-1838(83)90082-6","article-title":"Cardiovascular reflexes mediated by sympathetic afferent fibers","volume":"7","author":"Malliani","year":"1983","journal-title":"J Auton Nerv Syst"},{"key":"10.1016\/j.repc.2017.01.007_bib1055","first-page":"S24","article-title":"Twenty-four hour blood pressure variability: clinical implications","volume":"37","author":"Parati","year":"1992","journal-title":"Kidney Int Suppl"},{"key":"10.1016\/j.repc.2017.01.007_bib1060","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1002\/mus.20365","article-title":"Quantitative studies of autonomic function","volume":"33","author":"Hilz","year":"2006","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.repc.2017.01.007_bib1065","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1161\/01.RES.59.2.178","article-title":"Power spectral analysis of heart rate and arterial pressure variabilities as a marker of sympatho-vagal interaction in man and conscious dog","volume":"59","author":"Pagani","year":"1986","journal-title":"Circ Res"},{"key":"10.1016\/j.repc.2017.01.007_bib1070","first-page":"H867","article-title":"Hemodynamic regulation: investigation by spectral analysis","volume":"249","author":"Akselrod","year":"1985","journal-title":"Am J Physiol"},{"key":"10.1016\/j.repc.2017.01.007_bib1075","first-page":"H151","article-title":"Assessment of autonomic function in humans by heart rate spectral analysis","volume":"248","author":"Pomeranz","year":"1985","journal-title":"Am J Physiol"},{"key":"10.1016\/j.repc.2017.01.007_bib1080","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1093\/oxfordjournals.eurheartj.a014868","article-title":"Heart rate variability. Standards of measurement, physiological interpretation, and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology","volume":"17","year":"1996","journal-title":"Eur Heart J"},{"key":"10.1016\/j.repc.2017.01.007_bib1085","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1109\/51.620497","article-title":"Continuous monitoring of the sympatho-vagal balance through spectral analysis","volume":"16","author":"Bianchi","year":"1997","journal-title":"IEEE Eng Med Biol Mag"},{"key":"10.1016\/j.repc.2017.01.007_bib1090","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0165-1838(97)00011-8","article-title":"Autonomic response to change of posture among normal and mild-hypertensive adults: investigation by time-dependent spectral analysis","volume":"64","author":"Akselrod","year":"1997","journal-title":"J Auton Nerv Syst"},{"key":"10.1016\/j.repc.2017.01.007_bib1095","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1097\/00004872-198809000-00004","article-title":"Sympathetic predominance in essential hypertension: a study employing spectral analysis of heart rate variability","volume":"6","author":"Guzzetti","year":"1988","journal-title":"J Hypertens"},{"key":"10.1016\/j.repc.2017.01.007_bib1100","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1152\/physrev.1982.62.2.347","article-title":"Physiological aspects of primary hypertension","volume":"62","author":"Folkow","year":"1982","journal-title":"Physiol Rev"},{"key":"10.1016\/j.repc.2017.01.007_bib1105","first-page":"S11","article-title":"Stress, autonomic hyperactivity and essential hypertension: an enigma","volume":"3","author":"Julius","year":"1985","journal-title":"J Hypertens Suppl"},{"key":"10.1016\/j.repc.2017.01.007_bib1110","series-title":"A friendly guide to wavelets [electronic resource]","author":"Kaiser","year":"2011"},{"key":"10.1016\/j.repc.2017.01.007_bib1115","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1098\/rspa.1998.0193","article-title":"The empirical mode decomposition and the Hilbert spectrum for nonlinear and non-stationary time series analysis","volume":"454","author":"Huang","year":"1998","journal-title":"Proc R Soc Lond A"},{"key":"10.1016\/j.repc.2017.01.007_bib1120","series-title":"Autonomic nervous system: from physiology to clinics. Provas de Agrega\u00e7\u00e3o em Fisiologia","author":"Rocha","year":"2009"},{"key":"10.1016\/j.repc.2017.01.007_bib1125","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.autneu.2014.03.001","article-title":"Autonomic modulation in a patient with syncope and paroxysmal atrial-fibrillation","volume":"183","author":"Laranjo","year":"2014","journal-title":"Auton Neurosci"},{"key":"10.1016\/j.repc.2017.01.007_bib1130","first-page":"313","article-title":"A new method for evaluating the baroreflex role by a joint pattern analysis of pulse interval and systolic blood pressure series","volume":"23","author":"Di Rienzo","year":"1985","journal-title":"Med Biol Eng Comput"},{"key":"10.1016\/j.repc.2017.01.007_bib1135","series-title":"Computers in cardiology: proceedings IEEE computer society","first-page":"473","article-title":"Some experiments on ECG data compression in the presence of arrhythmias","author":"Bertinelli","year":"1988"},{"key":"10.1016\/j.repc.2017.01.007_bib1140","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1042\/cs1020465","article-title":"Advanced analysis of spontaneous baroreflex sensitivity, blood pressure and heart rate variability in patients with dilated cardiomyopathy","volume":"102","author":"Malberg","year":"2002","journal-title":"Clin Sci (Lond)"},{"key":"10.1016\/j.repc.2017.01.007_bib1145","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1097\/01.hjh.0000125439.28861.ed","article-title":"Time-domain cross-correlation baroreflex sensitivity: performance on the EUROBAVAR data set","volume":"22","author":"Westerhof","year":"2004","journal-title":"J Hypertens"},{"key":"10.1016\/j.repc.2017.01.007_bib1150","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.bspc.2009.03.003","article-title":"Time domain baroreflex sensitivity assessment by joint analysis of spontaneous SBP and RR series","volume":"4","author":"Gouveia","year":"2009","journal-title":"Biomed Signal Process Control"},{"key":"10.1016\/j.repc.2017.01.007_bib1155","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1161\/01.HYP.10.5.538","article-title":"Assessment of baroreceptor reflex sensitivity by means of spectral analysis","volume":"10","author":"Robbe","year":"1987","journal-title":"Hypertension"},{"key":"10.1016\/j.repc.2017.01.007_bib1160","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1161\/01.HYP.12.6.600","article-title":"Changes in autonomic regulation induced by physical training in mild hypertension","volume":"12","author":"Pagani","year":"1988","journal-title":"Hypertension"},{"key":"10.1016\/j.repc.2017.01.007_bib1165","series-title":"Studies in health technology and informatics","first-page":"21","article-title":"Autoregressive modeling for assessing closed-loop feedback and feedforward in the arterial baroreflex","author":"Barbieri","year":"1999"},{"key":"10.1016\/j.repc.2017.01.007_bib1170","series-title":"Studies in health technology and informatics","first-page":"101","article-title":"Multivariate time-variant autoregressive techniques for closed-loop cardiovascular control using simulations and comparisons","author":"Barbieri","year":"1997"},{"key":"10.1016\/j.repc.2017.01.007_bib1175","doi-asserted-by":"crossref","first-page":"H2558","DOI":"10.1152\/ajpheart.2000.279.5.H2558","article-title":"Assessing baroreflex gain from spontaneous variability in conscious dogs: role of causality and respiration","volume":"279","author":"Porta","year":"2000","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.repc.2017.01.007_bib1180","doi-asserted-by":"crossref","first-page":"H1830","DOI":"10.1152\/ajpheart.2001.280.4.H1830","article-title":"Causal linear parametric model for baroreflex gain assessment in patients with recent myocardial infarction","volume":"280","author":"Nollo","year":"2001","journal-title":"Am J Physiol Heart Circ Physiol"}],"container-title":["Revista Portuguesa de Cardiologia"],"original-title":[],"language":"pt","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0870255117306856?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0870255117306856?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:05:19Z","timestamp":1760108719000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0870255117306856"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10]]},"references-count":118,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2017,10]]}},"alternative-id":["S0870255117306856"],"URL":"https:\/\/doi.org\/10.1016\/j.repc.2017.01.007","relation":{},"ISSN":["0870-2551"],"issn-type":[{"value":"0870-2551","type":"print"}],"subject":[],"published":{"date-parts":[[2017,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Insights into the background of autonomic medicine","name":"articletitle","label":"Article Title"},{"value":"Revista Portuguesa de Cardiologia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.repc.2017.01.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Sociedade Portuguesa de Cardiologia. Published by Elsevier Espa\u00f1a, S.L.U.","name":"copyright","label":"Copyright"}]}}