{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T10:46:53Z","timestamp":1780483613985,"version":"3.54.1"},"reference-count":27,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,4,8]],"date-time":"2020-04-08T00:00:00Z","timestamp":1586304000000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Revista Portuguesa de Cardiologia"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1016\/j.repc.2019.08.010","type":"journal-article","created":{"date-parts":[[2020,5,26]],"date-time":"2020-05-26T17:35:48Z","timestamp":1590514548000},"page":"189-196","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Active acromegaly is associated with enhanced left ventricular contractility: Results from the three-dimensional speckle-tracking echocardiographic MAGYAR-Path Study"],"prefix":"10.1016","volume":"39","author":[{"given":"\u00c1rp\u00e1d","family":"Korm\u00e1nyos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e9ter","family":"Domsik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita","family":"Kalapos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N\u00e1ndor","family":"Gyenes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zsuzsanna","family":"Valkusz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Csaba","family":"Lengyel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tam\u00e1s","family":"Forster","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Attila","family":"Nemes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.repc.2019.08.010_bib0140","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S1042-3680(02)00035-9","article-title":"Pathology of pituitary tumors","volume":"14","author":"Sanno","year":"2003","journal-title":"Neurosurg Clin N Am"},{"key":"10.1016\/j.repc.2019.08.010_bib0145","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1210\/er.2002-0022","article-title":"Systemic complications of acromegaly: epidemiology, pathogenesis, and management","volume":"25","author":"Colao","year":"2004","journal-title":"Endocr Rev"},{"key":"10.1016\/j.repc.2019.08.010_bib0150","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1210\/er.2003-0009","article-title":"Cardiovascular function in acromegaly","volume":"24","author":"Clayton","year":"2003","journal-title":"Endocr Rev"},{"key":"10.1016\/j.repc.2019.08.010_bib0155","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1007\/s12020-016-1191-3","article-title":"Cardiovascular comorbidities in acromegaly: an update on their diagnosis and management","volume":"55","author":"Ramos-Levi","year":"2017","journal-title":"Endocrine"},{"key":"10.1016\/j.repc.2019.08.010_bib0160","doi-asserted-by":"crossref","first-page":"2558","DOI":"10.1056\/NEJMra062453","article-title":"Medical progress: acromegaly","volume":"355","author":"Melmed","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1016\/j.repc.2019.08.010_bib0165","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/j.echo.2009.05.021","article-title":"Comprehensive evaluation of left ventricular strain using speckle tracking echocardiography in normal adults: comparison of three-dimensional and two-dimensional approaches","volume":"22","author":"Saito","year":"2009","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.repc.2019.08.010_bib0170","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1111\/j.1540-8175.2012.01712.x","article-title":"Myocardial mechanics: understanding and applying three-dimensional speckle tracking echocardiography in clinical practice","volume":"29","author":"Ammar","year":"2012","journal-title":"Echocardiography"},{"key":"10.1016\/j.repc.2019.08.010_bib0175","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1007\/s11102-016-0772-8","article-title":"Acromegaly: clinical features at diagnosis","volume":"20","author":"Vilar","year":"2017","journal-title":"Pituitary"},{"key":"10.1016\/j.repc.2019.08.010_bib0180","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1093\/ehjci\/jev014","article-title":"Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging","volume":"16","author":"Lang","year":"2015","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.repc.2019.08.010_bib0185","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1556\/OH.2012.29466","article-title":"Three-dimensional speckle-tracking echocardiography \u2013 a further step in non-invasive three-dimensional cardiac imaging","volume":"153","author":"Nemes","year":"2012","journal-title":"Orv Hetil"},{"key":"10.1016\/j.repc.2019.08.010_bib0190","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1111\/j.1365-2265.2005.02370.x","article-title":"Hypertension in acromegaly and in the normal population: prevalence and determinants","volume":"63","author":"Vitale","year":"2005","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.repc.2019.08.010_bib0195","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1023\/A:1020798430884","article-title":"Pathogenesis and prevalence of hypertension in acromegaly","volume":"4","author":"Bondanelli","year":"2001","journal-title":"Pituitary"},{"key":"10.1016\/j.repc.2019.08.010_bib0200","doi-asserted-by":"crossref","first-page":"3174","DOI":"10.1210\/jcem.87.7.8643","article-title":"Early vascular alterations in acromegaly","volume":"87","author":"Brevetti","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.repc.2019.08.010_bib0205","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1046\/j.1365-2265.2001.01218.x","article-title":"Growth hormone and the heart","volume":"54","author":"Colao","year":"2001","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.repc.2019.08.010_bib0210","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.1365-2265.2007.03047.x","article-title":"High prevalence of cardiac hypertrophy without detectable signs of fibrosis in patients with untreated active acromegaly: an in vivo study using magnetic resonance imaging","volume":"68","author":"Bogazzi","year":"2008","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.repc.2019.08.010_bib0215","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1046\/j.1365-2265.2003.01780.x","article-title":"Growth hormone, acromegaly, and heart failure: an intricate triangulation","volume":"59","author":"Sacca","year":"2003","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.repc.2019.08.010_bib0220","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1159\/000438903","article-title":"Cardiovascular disease and sleep-disordered breathing in acromegaly","volume":"103","author":"Powlson","year":"2016","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.repc.2019.08.010_bib0225","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1210\/jc.2003-030849","article-title":"Increased prevalence of regurgitant valvular heart disease in acromegaly","volume":"89","author":"Pereira","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.repc.2019.08.010_bib0230","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1093\/oxfordjournals.eurheartj.a060047","article-title":"Arrhythmia profile in acromegaly","volume":"13","author":"Kahaly","year":"1992","journal-title":"Eur Heart J"},{"key":"10.1016\/j.repc.2019.08.010_bib0235","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1093\/eurheartj\/ehp187","article-title":"Quantification of left ventricular volumes using three-dimensional echocardiographic speckle tracking: comparison with MRI","volume":"30","author":"Nesser","year":"2009","journal-title":"Eur Heart J"},{"key":"10.1016\/j.repc.2019.08.010_bib0240","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1093\/ehjci\/jes030","article-title":"Comparison between three-dimensional speckle-tracking echocardiography and cardiac magnetic resonance imaging for quantification of left ventricular volumes and function","volume":"13","author":"Kleijn","year":"2012","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.repc.2019.08.010_bib0245","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1093\/ejechocard\/jer174","article-title":"Reliability of left ventricular volumes and function measurements using three-dimensional speckle tracking echocardiography","volume":"13","author":"Kleijn","year":"2012","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.repc.2019.08.010_bib0250","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/s11102-017-0795-9","article-title":"Two-dimensional speckle tracking echocardiography demonstrates no effect of active acromegaly on left ventricular strain","volume":"20","author":"Volschan","year":"2017","journal-title":"Pituitary"},{"key":"10.1016\/j.repc.2019.08.010_bib0255","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.ijcard.2006.11.196","article-title":"Aortic stiffness is increased in acromegaly \u2013 a transthoracic echocardiographic study","volume":"124","author":"Nemes","year":"2008","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.repc.2019.08.010_bib0260","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1002\/jcu.22529","article-title":"Left ventricular twist is impaired in acromegaly: insights from the three-dimensional speckle tracking echocardiographic MAGYAR-Path Study","volume":"46","author":"Kormanyos","year":"2018","journal-title":"J Clin Ultrasound"},{"key":"10.1016\/j.repc.2019.08.010_bib0265","doi-asserted-by":"crossref","first-page":"49","DOI":"10.4250\/jcu.2014.22.2.49","article-title":"Current status of 3-dimensional speckle tracking echocardiography: a review from our experiences","volume":"22","author":"Seo","year":"2014","journal-title":"J Cardiovasc Ultrasound"},{"key":"10.1016\/j.repc.2019.08.010_bib0270","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1016\/j.echo.2011.04.016","article-title":"Reproducibility and inter-vendor variability of left ventricular deformation measurements by three-dimensional speckle-tracking echocardiography","volume":"24","author":"Gayat","year":"2011","journal-title":"J Am Soc Echocardiogr"}],"container-title":["Revista Portuguesa de Cardiologia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0870255120301451?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0870255120301451?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:08:21Z","timestamp":1760108901000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0870255120301451"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["S0870255120301451"],"URL":"https:\/\/doi.org\/10.1016\/j.repc.2019.08.010","relation":{},"ISSN":["0870-2551"],"issn-type":[{"value":"0870-2551","type":"print"}],"subject":[],"published":{"date-parts":[[2020,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Active acromegaly is associated with enhanced left ventricular contractility: Results from the three-dimensional speckle-tracking echocardiographic MAGYAR-Path Study","name":"articletitle","label":"Article Title"},{"value":"Revista Portuguesa de Cardiologia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.repc.2019.08.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Sociedade Portuguesa de Cardiologia. Published by Elsevier Espa\u00f1a, S.L.U.","name":"copyright","label":"Copyright"}]}}