{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T16:14:04Z","timestamp":1788970444611,"version":"build-2803163510"},"reference-count":35,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,9,15]],"date-time":"2022-09-15T00:00:00Z","timestamp":1663200000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Revista Portuguesa de Cardiologia"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1016\/j.repc.2021.11.012","type":"journal-article","created":{"date-parts":[[2022,10,12]],"date-time":"2022-10-12T08:15:43Z","timestamp":1665562543000},"page":"41-47","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Does transcatheter ventricular septal defect closure affect heart rate variability in children?"],"prefix":"10.1016","volume":"42","author":[{"given":"Suleyman","family":"Sunkak","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ozge","family":"Pamukcu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Baykan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Onur","family":"Tasci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cagdas","family":"Vural","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazim","family":"Uzum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nazmi","family":"Narin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.repc.2021.11.012_bib0180","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1177\/1099800419877442","article-title":"Heart rate variability and risk of all-cause death and cardiovascular events in patients with cardiovascular disease: a meta-analysis of cohort studies","volume":"22","author":"Fang","year":"2020","journal-title":"Biol Res Nurs"},{"key":"10.1016\/j.repc.2021.11.012_bib0185","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1093\/europace\/eus341","article-title":"Heart rate variability and first cardiovascular event in populations without known cardiovascular disease: meta-analysis and dose\u2013response meta-regression","volume":"15","author":"Hillebrand","year":"2013","journal-title":"Europace"},{"key":"10.1016\/j.repc.2021.11.012_bib0190","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.jpsychores.2006.12.004","article-title":"Heart rate variability and markers of inflammation and coagulation in depressed patients with coronary heart disease","volume":"62","author":"Carney","year":"2007","journal-title":"J Psychosom Res"},{"key":"10.1016\/j.repc.2021.11.012_bib0195","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1017\/S1047951101000725","article-title":"The pathogenesis of heart failure in infants with congenital heart disease","volume":"11","author":"Buchhorn","year":"2001","journal-title":"Cardiol Young"},{"key":"10.1016\/j.repc.2021.11.012_bib0200","first-page":"290","article-title":"Heart rate variability improvement in children using transcatheter atrial septal defect closure","volume":"16","author":"\u00d6zy\u0131lmaz","year":"2016","journal-title":"Anatol J Cardiol"},{"key":"10.1016\/j.repc.2021.11.012_bib0205","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1136\/hrt.61.3.280","article-title":"Sinus arrhythmia in children with atrial septal defect: an analysis of heart rate variability before and after surgical repair","volume":"61","author":"Finley","year":"1989","journal-title":"Br Heart J"},{"key":"10.1016\/j.repc.2021.11.012_bib0210","doi-asserted-by":"crossref","first-page":"205","DOI":"10.4103\/0974-2069.189122","article-title":"Birth prevalence of congenital heart disease: a cross-sectional observational study from North India","volume":"9","author":"Saxena","year":"2016","journal-title":"Ann Pediatr Cardiol"},{"key":"10.1016\/j.repc.2021.11.012_bib0215","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.jpeds.2018.07.060","article-title":"Early childhood inpatient costs of critical congenital heart disease","volume":"203","author":"Pinto","year":"2018","journal-title":"J Pediatr"},{"key":"10.1016\/j.repc.2021.11.012_bib0220","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1016\/S0002-9149(97)00215-4","article-title":"Depressed heart rate variability as an independent predictor of death in chronic congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy","volume":"79","author":"Ponikowski","year":"1997","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.repc.2021.11.012_bib0225","first-page":"212","article-title":"Difference in autonomic nervous control between ventricular septal defect and atrial septal defect based on heart rate variability","volume":"1","author":"Hata","year":"2007","journal-title":"Pacing Clin Electrophysiol"},{"key":"10.1016\/j.repc.2021.11.012_bib0230","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1093\/oxfordjournals.eurheartj.a014868","article-title":"Heart rate variability. Standards of measurement, physiological interpretation, and clinical use. Task force of the European society of cardiology and the north American society of pacing and electrophysiology","volume":"17","year":"1996","journal-title":"Eur Heart J"},{"key":"10.1016\/j.repc.2021.11.012_bib0235","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/0002-9149(92)90502-P","article-title":"Clinical, hemodynamic and sympathetic neural correlates of heart rate variability in congestive heart failure","volume":"69","author":"Kienzle","year":"1992","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.repc.2021.11.012_bib0240","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1136\/hrt.67.6.482","article-title":"Decreased cardiac parasympathetic activity in chronic heart failure and its relation to left ventricular function","volume":"67","author":"Nolan","year":"1992","journal-title":"Br Heart J"},{"key":"10.1016\/j.repc.2021.11.012_bib0245","first-page":"36","article-title":"Baroreceptor function in congestive heart failure: effect on neurohumoral activation and regional vascular resistance","volume":"75","author":"Hirsch","year":"1987","journal-title":"Circulation"},{"key":"10.1016\/j.repc.2021.11.012_bib0250","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1159\/000006857","article-title":"Heart rate behavior in children with atrial septal defect","volume":"90","author":"Massin","year":"1998","journal-title":"Cardiology"},{"key":"10.1016\/j.repc.2021.11.012_bib0255","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1186\/s13023-014-0144-2","article-title":"Ventricular septal F defect","volume":"9","author":"Spicer","year":"2014","journal-title":"Orphanet J Rare Dis"},{"key":"10.1016\/j.repc.2021.11.012_bib0260","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/S0735-1097(97)00554-8","article-title":"Twenty-four hour time domain heart rate variability and heart rate: relations to age and gender over nine decades","volume":"31","author":"Umetani","year":"1998","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.repc.2021.11.012_bib0265","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/j.amjcard.2005.09.087","article-title":"Cardiac conduction disturbances seen after transcatheter device closure of muscular ventricular septal defects with the amplatzer occluder","volume":"97","author":"Robinson","year":"2006","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.repc.2021.11.012_bib0270","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0167-5273(97)00101-0","article-title":"Change of complex and periodic heart rate dynamics with change of pulmonary artery pressure in infants with left-to-right shunt lesion","volume":"60","author":"Kul Yum","year":"1997","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.repc.2021.11.012_bib0275","series-title":"Conference proceedings: annual international conference of the IEEE engineering in medicine and biology society","first-page":"4189","article-title":"Heart rate variability in children with cyanotic and acyanotic congenital heart disease: analysis by spectral and nonlinear indices","author":"Aletti","year":"2012"},{"key":"10.1016\/j.repc.2021.11.012_bib0280","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/S0140-6736(10)61339-6","article-title":"Ventricular septal defect","volume":"377","author":"Penny","year":"2011","journal-title":"Lancet"},{"key":"10.1016\/j.repc.2021.11.012_bib0285","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.ijcard.2018.06.097","article-title":"Heart rate variability is impaired in adults after closure of ventricular septal defect in childhood: a novel finding associated with right bundle branch block","volume":"274","author":"Heiberg","year":"2019","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.repc.2021.11.012_bib0290","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1080\/14017431.2017.1337216","article-title":"Permanent chronotropic impairment after closure of atrial or ventricular septal defect","volume":"51","author":"Heiberg","year":"2017","journal-title":"Scand Cardiovasc J"},{"key":"10.1016\/j.repc.2021.11.012_bib0295","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1007\/s00246-014-1037-9","article-title":"Does surgically induced right bundle branch block really effect ventricular function in children after ventricular septal defect closure?","volume":"36","author":"Karadeniz","year":"2015","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.repc.2021.11.012_bib0300","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1017\/S104795111700107X","article-title":"Mid-term results of percutaneous ventricular septal defect closure with Amplatzer Duct Occluder-II in children","volume":"27","author":"Pamukcu","year":"2017","journal-title":"Cardiol Young"},{"key":"10.1016\/j.repc.2021.11.012_bib0305","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1007\/s00246-018-1852-5","article-title":"Percutaneous ventricular septal defect closure in patients under 1 year of age","volume":"39","author":"Narin","year":"2018","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.repc.2021.11.012_bib0310","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.biopsycho.2005.11.014","article-title":"Toward understanding respiratory sinus arrhythmia: relations to cardiac vagal tone, evolution and biobehavioral functions","volume":"74","author":"Grossman","year":"2007","journal-title":"Biol Psychol"},{"key":"10.1016\/j.repc.2021.11.012_bib0315","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.3389\/fpsyg.2014.01040","article-title":"A healthy heart is not a metronome: an integrative review of the heart's anatomy and heart rate variability","volume":"5","author":"Shaffer","year":"2014","journal-title":"Front Psychol"},{"key":"10.1016\/j.repc.2021.11.012_bib0320","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1007\/s00408-003-1034-x","article-title":"Ventricular arrhythmias and autonomic profile in patients with primary pulmonary hypertension","volume":"181","author":"Folino","year":"2003","journal-title":"Lung"},{"key":"10.1016\/j.repc.2021.11.012_bib0325","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1183\/09031936.00145708","article-title":"Impaired cardiac autonomic control relates to disease severity in pulmonary hypertension","volume":"34","author":"Wensel","year":"2009","journal-title":"Eur Respir J"},{"key":"10.1016\/j.repc.2021.11.012_bib0330","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.ijcard.2008.12.087","article-title":"Heart rate variability predicts outcome in children with pulmonary arterial hypertension","volume":"142","author":"Lammers","year":"2010","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.repc.2021.11.012_bib0335","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/j.hrtlng.2014.05.010","article-title":"Heart rate variability parameters and ventricular arrhythmia correlate with pulmonary arterial pressure in adult patients with idiopathic pulmonary arterial hypertension","volume":"43","author":"Yi","year":"2014","journal-title":"Heart Lung"},{"key":"10.1016\/j.repc.2021.11.012_bib0340","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.jacc.2005.09.028","article-title":"Transcatheter closure of perimembranous ventricular septal defects using the new Amplatzer membranous VSD occluder: results of the U.S. phase I trial","volume":"47","author":"Fu","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.repc.2021.11.012_bib0345","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.amjcard.2005.09.068","article-title":"Transcatheter closure of congenital ventricular septal defect with Amplatzer septal occluders","volume":"96","author":"Carminati","year":"2005","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.repc.2021.11.012_bib0350","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1016\/j.athoracsur.2006.04.030","article-title":"Is complete heart block after surgical closure of ventricular septum defects still an issue?","volume":"82","author":"Andersen","year":"2006","journal-title":"Ann Thorac Surg"}],"container-title":["Revista Portuguesa de Cardiologia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0870255122004528?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0870255122004528?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:11:59Z","timestamp":1760109119000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0870255122004528"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["S0870255122004528"],"URL":"https:\/\/doi.org\/10.1016\/j.repc.2021.11.012","relation":{},"ISSN":["0870-2551"],"issn-type":[{"value":"0870-2551","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Does transcatheter ventricular septal defect closure affect heart rate variability in children?","name":"articletitle","label":"Article Title"},{"value":"Revista Portuguesa de Cardiologia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.repc.2021.11.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Sociedade Portuguesa de Cardiologia. Published by Elsevier Espa\u00f1a, S.L.U.","name":"copyright","label":"Copyright"}]}}