{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T05:21:10Z","timestamp":1761888070860,"version":"build-2065373602"},"reference-count":21,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,10,22]],"date-time":"2021-10-22T00:00:00Z","timestamp":1634860800000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Revista Portuguesa de Cardiologia (English Edition)"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1016\/j.repce.2021.10.012","type":"journal-article","created":{"date-parts":[[2021,11,29]],"date-time":"2021-11-29T11:41:54Z","timestamp":1638186114000},"page":"801.e1-801.e6","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Beware of regression of electrocardiographic abnormalities on detraining \u2013 It may not always mean \u2018athlete's heart\u2019"],"prefix":"10.1016","volume":"40","author":[{"given":"Jos\u00e9 Pedro","family":"Marques","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ant\u00f3nio","family":"Freitas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o","family":"Abecasis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.repce.2021.10.012_bib0110","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1038\/nrcardio.2016.140","article-title":"Update on hypertrophic cardiomyopathy and a guide to the guidelines","volume":"13","author":"Sen-Chowdhry","year":"2016","journal-title":"Nat Rev Cardiol"},{"key":"10.1016\/j.repce.2021.10.012_bib0115","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.jacc.2014.05.003","article-title":"Hypertrophic cardiomyopathy: present and future, with translation into contemporary cardiovascular medicine","volume":"64","author":"Maron","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.repce.2021.10.012_bib0120","first-page":"e003312","article-title":"Hypertrophic cardiomyopathy athlete's heart, or both","volume":"8","author":"Kebed","year":"2015","journal-title":"Circulation: Cardiovasc Imag"},{"key":"10.1016\/j.repce.2021.10.012_bib0125","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1016\/j.amjcard.2014.07.070","article-title":"Differentiating left ventricular hypertrophy in athletes from that in patients with hypertrophic cardiomyopathy","volume":"114","author":"Caselli","year":"2014","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.repce.2021.10.012_bib0130","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1056\/NEJM199101313240504","article-title":"The upper limit of physiologic cardiac hypertrophy in highly trained elite athletes","volume":"324","author":"Pelliccia","year":"1991","journal-title":"N Engl J Med"},{"key":"10.1016\/j.repce.2021.10.012_bib0135","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1136\/bjsports-2015-094636","article-title":"What's the big deal about T-wave inversion in athletes?. A guide to clinical interpretation","volume":"50","author":"Wilson","year":"2016","journal-title":"Br J Sports Med"},{"key":"10.1016\/j.repce.2021.10.012_bib0140","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1136\/bjsports-2012-092067","article-title":"Electrocardiographic interpretation in athletes: the \u2018Seattle criteria\u2019","volume":"47","author":"Drezner","year":"2013","journal-title":"Br J Sports Med"},{"key":"10.1016\/j.repce.2021.10.012_bib0145","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.repc.2014.07.010","article-title":"The hearts of competitive athletes: an up-to-date overview of exercise-induced cardiac adaptations","volume":"34","author":"Dores","year":"2015","journal-title":"Rev Portug Cardiol"},{"key":"10.1016\/j.repce.2021.10.012_bib0150","doi-asserted-by":"crossref","first-page":"e153","DOI":"10.1016\/j.jtcvs.2011.10.020","article-title":"ACCF\/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: a report of the American College of Cardiology Foundation\/American Heart Association Task Force on Practice Guidelines","volume":"142","author":"Gersh","year":"2011","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"Suppl. I","key":"10.1016\/j.repce.2021.10.012_bib0155","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1136\/bjsports-2011-090838","article-title":"Significance of deep T-wave inversions in asymptomatic athletes with normal cardiovascular examinations: practical solutions for managing the diagnostic conundrum","volume":"46","author":"Wilson","year":"2012","journal-title":"Br J Sports Med"},{"key":"10.1016\/j.repce.2021.10.012_bib0160","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1056\/NEJMoa060781","article-title":"Outcomes in athletes with marked ECG repolarization abnormalities","volume":"358","author":"Pelliccia","year":"2008","journal-title":"N Engl J Med"},{"key":"10.1016\/j.repce.2021.10.012_bib0165","doi-asserted-by":"crossref","first-page":"2304","DOI":"10.1093\/eurheartj\/ehr140","article-title":"The prevalence, distribution, and clinical outcomes of electrocardiographic repolarization patterns in male athletes of African\/Afro-Caribbean origin","volume":"32","author":"Papadakis","year":"2011","journal-title":"Eur Heart J"},{"key":"10.1016\/j.repce.2021.10.012_bib0170","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1136\/heartjnl-2014-306110","article-title":"Echocardiographic findings in 2261 peri-pubertal athletes with or without inverted T waves at electrocardiogram","volume":"101","author":"Cal\u00f2","year":"2015","journal-title":"Heart"},{"key":"10.1016\/j.repce.2021.10.012_bib0175","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1161\/CIRCULATIONAHA.114.011038","article-title":"Recognition and significance of pathological T-wave inversions in athletes","volume":"131","author":"Schnell","year":"2015","journal-title":"Circulation"},{"key":"10.1016\/j.repce.2021.10.012_bib0180","doi-asserted-by":"crossref","first-page":"2733","DOI":"10.1093\/eurheartj\/ehu284","article-title":"2014 ESC guidelines on diagnosis and management of hypertrophic cardiomyopathy","volume":"35","author":"Elliott","year":"2014","journal-title":"Eur Heart J"},{"key":"10.1016\/j.repce.2021.10.012_bib0185","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.ijcard.2015.01.054","article-title":"Diagnosis of apical hypertrophic cardiomyopathy: T-wave inversion and relative but not absolute apical left ventricular hypertrophy","volume":"183","author":"Flett","year":"2015","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.repce.2021.10.012_bib0190","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1186\/1532-429X-18-S1-P277","article-title":"CMR assessment of the left ventricle apical morphology in subjects with giant t-wave inversions and without apical wall thickness >15 mm","volume":"18","author":"Lu","year":"2016","journal-title":"J Cardiovasc Magn Reson"},{"key":"10.1016\/j.repce.2021.10.012_bib0195","doi-asserted-by":"crossref","first-page":"2593","DOI":"10.1093\/eurheartj\/ehp306","article-title":"Disease penetrance and risk stratification for sudden cardiac death in asymptomatic hypertrophic cardiomyopathy mutation carriers","volume":"30","author":"Michels","year":"2009","journal-title":"Eur Heart J"},{"key":"10.1016\/j.repce.2021.10.012_bib0200","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1016\/j.jmb.2009.02.006","article-title":"The role of the N-terminus of the myosin essential light chain in cardiac muscle contraction","volume":"387","author":"Kazmierczak","year":"2009","journal-title":"J Mol Biol"},{"key":"10.1016\/j.repce.2021.10.012_bib0205","first-page":"557","article-title":"Detraining-related changes in left ventricular wall thickness and longitudinal strain in a young athlete likely to have hypertrophic cardiomyopathy","volume":"11","author":"de Gregorio","year":"2012","journal-title":"J Sports Sci Med"},{"key":"10.1016\/j.repce.2021.10.012_bib0210","doi-asserted-by":"crossref","first-page":"2362","DOI":"10.1016\/j.jacc.2015.09.035","volume":"66","author":"Maron","year":"2015","journal-title":"J Am Coll Cardiol"}],"container-title":["Revista Portuguesa de Cardiologia (English Edition)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2174204921003147?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2174204921003147?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T03:40:55Z","timestamp":1761882055000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2174204921003147"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":21,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["S2174204921003147"],"URL":"https:\/\/doi.org\/10.1016\/j.repce.2021.10.012","relation":{},"ISSN":["2174-2049"],"issn-type":[{"type":"print","value":"2174-2049"}],"subject":[],"published":{"date-parts":[[2021,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Beware of regression of electrocardiographic abnormalities on detraining \u2013 It may not always mean \u2018athlete's heart\u2019","name":"articletitle","label":"Article Title"},{"value":"Revista Portuguesa de Cardiologia (English Edition)","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.repce.2021.10.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.repc.2018.07.012","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Sociedade Portuguesa de Cardiologia. Published by Elsevier Espa\u00f1a, S.L.U.","name":"copyright","label":"Copyright"}]}}