{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T03:50:43Z","timestamp":1777521043893,"version":"3.51.4"},"reference-count":45,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2006,4,1]],"date-time":"2006-04-01T00:00:00Z","timestamp":1143849600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,4,1]],"date-time":"2006-04-01T00:00:00Z","timestamp":1143849600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Reproductive Toxicology"],"published-print":{"date-parts":[[2006,4]]},"DOI":"10.1016\/j.reprotox.2005.09.006","type":"journal-article","created":{"date-parts":[[2005,10,24]],"date-time":"2005-10-24T14:12:38Z","timestamp":1130163158000},"page":"271-279","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Rapid action of pesticides on cytosolic calcium concentrations in cultures of human umbilical vein endothelial cells"],"prefix":"10.1016","volume":"21","author":[{"given":"Edward V.","family":"Younglai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanjing","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Warren G.","family":"Foster","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.reprotox.2005.09.006_bib1","doi-asserted-by":"crossref","first-page":"2072","DOI":"10.1210\/jcem.85.5.6516","article-title":"Mannheim classification of nongenomically initiated (rapid) steroid action(s)","volume":"85","author":"Falkenstein","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.reprotox.2005.09.006_bib2","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.1095\/biolreprod.103.026187","article-title":"Dichlorodiphenylchloroethylene elevates cytosolic calcium concentrations and oscillations in primary cultures of human granulosa-lutein cells","volume":"70","author":"Younglai","year":"2004","journal-title":"Biol Reprod"},{"key":"10.1016\/j.reprotox.2005.09.006_bib3","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1210\/en.2004-1064","article-title":"Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells","volume":"146","author":"Thomas","year":"2005","journal-title":"Endocrinology"},{"key":"10.1016\/j.reprotox.2005.09.006_bib4","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1210\/endo.140.4.6781","article-title":"Pesticides interfere with the nongenomic action of a progestogen on meiotic maturation by binding to its plasma membrane receptor on fish oocytes","volume":"140","author":"Das","year":"1999","journal-title":"Endocrinology"},{"key":"10.1016\/j.reprotox.2005.09.006_bib5","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S0141-1136(97)00090-1","article-title":"The teleost sperm membrane progestogen receptor: interactions with xenoestrogens","volume":"46","author":"Thomas","year":"1998","journal-title":"Mar Environ Res"},{"key":"10.1016\/j.reprotox.2005.09.006_bib6","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1289\/ehp.7330","article-title":"Necessity to measure PCBs and organochlorine pesticide concentrations in human umbilical cords for fetal exposure assessment","volume":"113","author":"Fukata","year":"2005","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.reprotox.2005.09.006_bib7","doi-asserted-by":"crossref","first-page":"2954","DOI":"10.1210\/jcem.85.8.6850","article-title":"Detection of endocrine disrupting chemicals in samples of second trimester human amniotic fluid","volume":"85","author":"Foster","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.reprotox.2005.09.006_bib8","doi-asserted-by":"crossref","first-page":"2466","DOI":"10.1073\/pnas.87.7.2466","article-title":"Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2+ ATPase","volume":"87","author":"Thastrup","year":"1990","journal-title":"Proc Natl Acad Sci"},{"key":"10.1016\/j.reprotox.2005.09.006_bib9","doi-asserted-by":"crossref","first-page":"17816","DOI":"10.1016\/S0021-9258(19)84646-X","article-title":"Cyclopiazonic acid is a specific inhibitor of the Ca2+-ATPase of sarcoplasmic reticulum","volume":"264","author":"Seidler","year":"1989","journal-title":"J Biol Chem"},{"key":"10.1016\/j.reprotox.2005.09.006_bib10","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1126\/science.1902986","article-title":"Diversity of G protein in signal transduction","volume":"252","author":"Simon","year":"1991","journal-title":"Science"},{"key":"10.1016\/j.reprotox.2005.09.006_bib11","first-page":"3","article-title":"Nongenomic actions of steroid hormones in reproductive tissues","volume":"19","author":"Revelli","year":"1998","journal-title":"Endocr Rev"},{"key":"10.1016\/j.reprotox.2005.09.006_bib12","first-page":"853","article-title":"Nongenomic actions of steroids\u2014from laboratory to clinical implications","volume":"13","author":"Gerdes","year":"2000","journal-title":"J Paedtr Endocrinol Metab"},{"key":"10.1016\/j.reprotox.2005.09.006_bib13","doi-asserted-by":"crossref","first-page":"1860","DOI":"10.1152\/jappl.2001.91.4.1860","article-title":"Cell localization, physiology, and nongenomic actions of estrogen receptors","volume":"91","author":"Levin","year":"2001","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.reprotox.2005.09.006_bib14","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1530\/rep.0.1250003","article-title":"Non-genomic progesterone receptors in the mammalian ovary: some unresolved issues","volume":"125","author":"Bramley","year":"2003","journal-title":"Reproduction"},{"key":"10.1016\/j.reprotox.2005.09.006_bib15","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.jsbmb.2004.01.004","article-title":"Nongenomic effects of 17beta-estradiol-diversity of membrane binding sites","volume":"88","author":"Sak","year":"2004","journal-title":"J Steroid Biochem Mol Biol"},{"key":"10.1016\/j.reprotox.2005.09.006_bib16","doi-asserted-by":"crossref","first-page":"5930","DOI":"10.1073\/pnas.97.11.5930","article-title":"Human vascular endothelial cells contain membrane binding sites for estradiol, which mediate rapid intracellular signaling","volume":"97","author":"Russell","year":"2000","journal-title":"Proc Natl Acad Sci"},{"key":"10.1016\/j.reprotox.2005.09.006_bib17","doi-asserted-by":"crossref","first-page":"7460","DOI":"10.1074\/jbc.M411565200","article-title":"Resveratrol and estradiol rapidly activate MAPK signaling through estrogen receptors alpha and beta in endothelial cells","volume":"280","author":"Klinge","year":"2005","journal-title":"J Biol Chem"},{"key":"10.1016\/j.reprotox.2005.09.006_bib18","doi-asserted-by":"crossref","first-page":"17126","DOI":"10.1073\/pnas.0407492101","article-title":"Striatin assembles a membrane signaling complex necessary for rapid, nongenomic activation of endothelial NO synthase by estrogen receptor","volume":"101","author":"Lu","year":"2004","journal-title":"Proc Natl Acad Sci"},{"key":"10.1016\/j.reprotox.2005.09.006_bib19","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1038\/sj.bjp.0703252","article-title":"Enhanced relaxation of porcine coronary arteries after acute exposure to a physiological level of 17 beta-estradiol involves non-genomic mechanisms and the cyclic AMP cascade","volume":"129","author":"Teoh","year":"2000","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.reprotox.2005.09.006_bib20","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1177\/002215540305100808","article-title":"Membrane-bound progesterone receptor expression in human aortic endothelial cells","volume":"51","author":"Welter","year":"2003","journal-title":"J Histochem Cytochem"},{"key":"10.1016\/j.reprotox.2005.09.006_bib21","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0303-7207(02)00380-5","article-title":"Cloning and expression of a novel, truncated, progesterone receptor","volume":"200","author":"Saner","year":"2003","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.reprotox.2005.09.006_bib22","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/j.steroids.2003.08.006","article-title":"In vitro effects of progesterone and progestins on vascular cells","volume":"68","author":"Simoncini","year":"2003","journal-title":"Steroids"},{"key":"10.1016\/j.reprotox.2005.09.006_bib23","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0167-4889(00)00112-9","article-title":"Differential effects of progesterone and 17beta-estradiol on the Ca(2+) entry induced by thapsigargin and endothelin-1 in in situ endothelial cells","volume":"1499","author":"Toshima","year":"2000","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.reprotox.2005.09.006_bib24","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0014-2999(99)00438-0","article-title":"Progesterone modulates estradiol actions: acute effects at physiological concentrations","volume":"378","author":"Teoh","year":"1999","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.reprotox.2005.09.006_bib25","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/0002-9378(74)90209-9","article-title":"Plasma estrone, estradiol, estriol, progesterone, and cortisol in normal labour","volume":"119","author":"Okada","year":"1974","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.reprotox.2005.09.006_bib26","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1210\/jcem-51-6-1235","article-title":"Plasma steroid concentrations in maternal and umbilical circulation after spontaneous onset of labor","volume":"51","author":"Mathur","year":"1980","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.reprotox.2005.09.006_bib27","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.1093\/humrep\/dei078","article-title":"Non-genomic action of estradiol and progesterone on cytosolic calcium concentrations in primary cultures of human granulosa-lutein cells","volume":"20","author":"Younglai","year":"2005","journal-title":"Hum Reprod"},{"key":"10.1016\/j.reprotox.2005.09.006_bib28","doi-asserted-by":"crossref","first-page":"C227","DOI":"10.1152\/ajpcell.1978.235.5.C227","article-title":"Mechanism of membrane stabilization by calcium in vascular smooth muscle","volume":"235","author":"Webb","year":"1978","journal-title":"Am J Physiol"},{"key":"10.1016\/j.reprotox.2005.09.006_bib29","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0005-2736(97)00136-3","article-title":"Dual effects of extracellular Ca2+ on cardiotoxin-induced cytotoxicity and cytosolic Ca2+ changes in cultured single cells of rabbit aortic endothelium","volume":"1330","author":"Ou","year":"1997","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.reprotox.2005.09.006_bib30","doi-asserted-by":"crossref","first-page":"3788","DOI":"10.1210\/en.2004-0149","article-title":"A membrane estrogen receptor mediates intracellular calcium release in astrocytes","volume":"145","author":"Chaban","year":"2004","journal-title":"Endocrinology"},{"key":"10.1016\/j.reprotox.2005.09.006_bib31","doi-asserted-by":"crossref","first-page":"2053","DOI":"10.1016\/S0006-2952(03)00584-7","article-title":"Inhibitory action of ICI-182780, an estrogen receptor antagonist, on BKCa channel activity in cultured endothelial cells of human coronary artery","volume":"66","author":"Liu","year":"2003","journal-title":"Biochem Pharmacol"},{"key":"10.1016\/j.reprotox.2005.09.006_bib32","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1146\/annurev.med.48.1.129","article-title":"RU486 (Mifepristone): mechanisms of action and clinical uses","volume":"48","author":"Cadepond","year":"1999","journal-title":"Annu Rev Med"},{"key":"10.1016\/j.reprotox.2005.09.006_bib33","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1093\/humrep\/deh803","article-title":"Progestogens stimulate prostacyclin production by human endothelial cells","volume":"20","author":"Hermenegildo","year":"2005","journal-title":"Hum Reprod"},{"key":"10.1016\/j.reprotox.2005.09.006_bib34","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1095\/biolreprod62.4.995","article-title":"Effects of estrogens and xenoestrogens on androgen production by Atlantic croaker testes in vitro: evidence for a nongenomic action mediated by an estrogen membrane receptor","volume":"62","author":"Loomis","year":"2000","journal-title":"Biol Reprod"},{"key":"10.1016\/j.reprotox.2005.09.006_bib35","doi-asserted-by":"crossref","first-page":"6328","DOI":"10.1021\/es0403662","article-title":"Disruption of rapid, nongenomic steroid actions by environmental chemicals: interference with progestin stimulation of sperm motility in Atlantic croaker","volume":"38","author":"Thomas","year":"2004","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.reprotox.2005.09.006_bib36","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1096\/fasebj.12.7.613","article-title":"Environmental estrogenic pollutants induce acute vascular relaxation by inhibiting L-type Ca2+ channels in smooth muscle cells","volume":"12","author":"Ruehlmann","year":"1998","journal-title":"FASEB J."},{"key":"10.1016\/j.reprotox.2005.09.006_bib37","doi-asserted-by":"crossref","first-page":"11603","DOI":"10.1073\/pnas.97.21.11603","article-title":"Nongenomic actions of estrogens and xenoestrogens by binding at a plasma membrane receptor unrelated to estrogen receptor \u03b1 and estrogen receptor \u03b2","volume":"97","author":"Nadal","year":"2000","journal-title":"Proc Natl Acad Sci"},{"key":"10.1016\/j.reprotox.2005.09.006_bib38","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1006\/taap.1995.1217","article-title":"The chlorinated insecticide 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane (p,p\u2032-DDD) increases intracellular calcium in rat myometrial smooth muscle cells","volume":"135","author":"Juberg","year":"1995","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1016\/j.reprotox.2005.09.006_bib39","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1289\/ehp.7505","article-title":"Xenoestrogens at picomolar to nanomolar concentrations trigger membrane estrogen receptor-alpha-mediated Ca++ fluxes and prolactin release in GH3\/B6 pituitary tumor cells","volume":"113","author":"Wozniak","year":"2005","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.reprotox.2005.09.006_bib40","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.steroids.2005.03.002","article-title":"Signaling from the membrane via membrane estrogen receptor-alpha: estrogens, xenoestrogens, and phytoestrogens","volume":"70","author":"Watson","year":"2005","journal-title":"Steroids"},{"key":"10.1016\/j.reprotox.2005.09.006_bib41","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1590\/S0036-36342000000500003","article-title":"Carry-over of persistent organochlorine pesticides through placenta to fetus","volume":"42","author":"Waliszewski","year":"2000","journal-title":"Salud Publica Mex"},{"key":"10.1016\/j.reprotox.2005.09.006_bib42","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1002\/jcb.10558","article-title":"Estrogenic endocrine disruptive components interfere with calcium handling and differentiation of human trophoblast cells","volume":"89","author":"Derfoul","year":"2003","journal-title":"J Cell Biochem"},{"key":"10.1016\/j.reprotox.2005.09.006_bib43","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1038\/35036035","article-title":"The versatility and universality of calcium signalling","volume":"1","author":"Berridge","year":"2000","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1016\/j.reprotox.2005.09.006_bib44","doi-asserted-by":"crossref","first-page":"2213","DOI":"10.1242\/jcs.114.12.2213","article-title":"The organization and functions of local Ca2+ signals","volume":"114","author":"Bootman","year":"2001","journal-title":"J Cell Sci"},{"key":"10.1016\/j.reprotox.2005.09.006_bib45","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1038\/nrm1155","article-title":"Calcium signaling: dynamics, homeostasis and remodelling","volume":"4","author":"Berridge","year":"2003","journal-title":"Nat Rev Mol Cell Biol"}],"container-title":["Reproductive Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890623805002157?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890623805002157?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:23:07Z","timestamp":1760188987000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0890623805002157"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,4]]},"references-count":45,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2006,4]]}},"alternative-id":["S0890623805002157"],"URL":"https:\/\/doi.org\/10.1016\/j.reprotox.2005.09.006","relation":{},"ISSN":["0890-6238"],"issn-type":[{"value":"0890-6238","type":"print"}],"subject":[],"published":{"date-parts":[[2006,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Rapid action of pesticides on cytosolic calcium concentrations in cultures of human umbilical vein endothelial cells","name":"articletitle","label":"Article Title"},{"value":"Reproductive Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.reprotox.2005.09.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}