{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T17:07:54Z","timestamp":1764781674615,"version":"build-2065373602"},"reference-count":22,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2006,10,1]],"date-time":"2006-10-01T00:00:00Z","timestamp":1159660800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,10,1]],"date-time":"2006-10-01T00:00:00Z","timestamp":1159660800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Reproductive Toxicology"],"published-print":{"date-parts":[[2006,10]]},"DOI":"10.1016\/j.reprotox.2006.03.018","type":"journal-article","created":{"date-parts":[[2006,5,20]],"date-time":"2006-05-20T07:22:30Z","timestamp":1148109750000},"page":"501-507","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Pathogenetic transition in the morphology of abnormal sperm in the testes and the caput, corpus, and cauda epididymides of male rats after treatment with 4,6-dinitro-o-cresol"],"prefix":"10.1016","volume":"22","author":[{"given":"Ken L.","family":"Takahashi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naofumi","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hitoshi","family":"Hojo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maki","family":"Kuwahara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroaki","family":"Aoyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoji","family":"Teramoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.reprotox.2006.03.018_bib1","series-title":"Handbook of Pesticide Toxicology, Agents","first-page":"1169","article-title":"Inhibitors and uncouplers of mitochondrial oxidative phosphorylation","author":"Hollingworth","year":"2001"},{"key":"10.1016\/j.reprotox.2006.03.018_bib2","first-page":"1191","article-title":"Nitro compounds and related phenolic pesticides","volume":"vol. 3","author":"Gasiewicz","year":"1991"},{"key":"10.1016\/j.reprotox.2006.03.018_bib3","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1006\/taap.1994.1138","article-title":"Interactions of herbicides 2,4-D and dinoseb with liver mitochondrial bioenergetics","volume":"127","author":"Palmeira","year":"1994","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1016\/j.reprotox.2006.03.018_bib4","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/S1357-2725(97)00041-1","article-title":"4,6-Dinitro-o-cresol uncouples oxidative phosphorylation and induces membrane permeability transition in rat liver mitochondria","volume":"29","author":"Castilho","year":"1997","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1016\/j.reprotox.2006.03.018_bib5","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/0147-6513(81)90044-0","article-title":"The teratogenic and mutagenic effects of dinitro-o-cresol containing herbicide on the laboratory mice","volume":"5","author":"Nehez","year":"1981","journal-title":"Ecotoxicol Environ Saf"},{"key":"10.1016\/j.reprotox.2006.03.018_bib6","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S0890-6238(02)00130-2","article-title":"Effects of dinoseb, 4,6-dinitro-o-cresol, and 2,4-dinitrophenol on rat Sertoli-germ cell co-cultures","volume":"17","author":"Takahashi","year":"2003","journal-title":"Reprod Toxicol"},{"key":"10.1016\/j.reprotox.2006.03.018_bib7","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.reprotox.2004.02.009","article-title":"Comparative studies on the spermatotoxic effects of dinoseb and its structurally related chemicals","volume":"18","author":"Takahashi","year":"2004","journal-title":"Reprod Toxicol"},{"key":"10.1016\/j.reprotox.2006.03.018_bib8","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/0890-6238(92)90034-Q","article-title":"Endopoints of spermatotoxicity in the rat after short duration exposures to fourteen reproductive toxicants","volume":"6","author":"Linder","year":"1992","journal-title":"Reprod Toxicol"},{"key":"10.1016\/j.reprotox.2006.03.018_bib9","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1007\/BF01056075","article-title":"Testicular effects of dinoseb in rats","volume":"11","author":"Linder","year":"1982","journal-title":"Arch Environ Contam Toxicol"},{"key":"10.1016\/j.reprotox.2006.03.018_bib10","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/0041-008X(83)90180-1","article-title":"The comparative effects of 1,2-dibromo-3-chloropropane (DBCP) and its metabolites, 3-chloro-1,2-propaneoxide (epichlorohydrin), 3-chloro-1,2-propanediol (alphachlorohydrin), and oxalic acid, on the urogenital system of male rats","volume":"70","author":"Kluwe","year":"1983","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1016\/j.reprotox.2006.03.018_bib11","doi-asserted-by":"crossref","first-page":"233","DOI":"10.3109\/01485018308987487","article-title":"Induction of morphologically abnormal sperm in rats exposed to o-xylene","volume":"11","author":"Washington","year":"1983","journal-title":"Arch Androl"},{"key":"10.1016\/j.reprotox.2006.03.018_bib12","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/0041-008X(86)90263-2","article-title":"In vivo and in vitro evaluations of spermatotoxicity induced by 2-ethoxyethanol treatment","volume":"84","author":"Oudiz","year":"1986","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1016\/j.reprotox.2006.03.018_bib13","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/0272-0590(88)90117-0","article-title":"Comparison of changes in serum androgen binding protein with germinal epithelial damage and infertility induced by di-n-pentyl phthalate","volume":"11","author":"Lindstrom","year":"1988","journal-title":"Fund Appl Toxicol"},{"key":"10.1016\/j.reprotox.2006.03.018_bib14","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/0272-0590(89)90014-6","article-title":"Effect of metronidazole on fertility and testicular function in male rats","volume":"12","author":"McClain","year":"1989","journal-title":"Fund Appl Toxicol"},{"key":"10.1016\/j.reprotox.2006.03.018_bib15","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/0272-0590(91)90224-R","article-title":"Toxicity studies of acetone administered in the drinking water of rodents","volume":"17","author":"Dietz","year":"1991","journal-title":"Fund Appl Toxicol"},{"key":"10.1016\/j.reprotox.2006.03.018_bib16","first-page":"270","article-title":"Dose dependent effects of inhaled ethylene oxide on spermatogenesis in rats","volume":"48","author":"Mori","year":"1991","journal-title":"Br J Ind Med"},{"key":"10.1016\/j.reprotox.2006.03.018_bib17","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1002\/j.1939-4640.1992.tb00345.x","article-title":"Acute and long-term effects of a single dose of the fungicide carbendazim (methyl 2-benzimidazole carbamate) on the male reproductive system in the rat","volume":"13","author":"Nakai","year":"1992","journal-title":"J Androl"},{"key":"10.1016\/j.reprotox.2006.03.018_bib18","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1006\/faat.1996.0108","article-title":"Testicular toxicity of gallium arsenide, indium arsenide, and arsenic oxide in rats by repetitive intratracheal instillation","volume":"32","author":"Omura","year":"1996","journal-title":"Fund Appl Toxicol"},{"key":"10.1016\/j.reprotox.2006.03.018_bib19","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1093\/toxsci\/54.2.416","article-title":"Reproductive toxicity of 1-bromopropane, a newly introduced alternative to ozone layer depleting solvents, in male rats","volume":"54","author":"Ichihara","year":"2000","journal-title":"Toxicol Sci"},{"key":"10.1016\/j.reprotox.2006.03.018_bib20","first-page":"285","article-title":"Guideline for animal experimentation. Japanese Association for Laboratory Animal Science","volume":"36","author":"JALAS","year":"1987","journal-title":"Exp Anim"},{"key":"10.1016\/j.reprotox.2006.03.018_bib21","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1002\/mrd.1080340209","article-title":"Improved preservation of rat epididymal sperm for high-resolution low-voltage scanning electron microscopy (HR-LVSEM)","volume":"34","author":"Stoffel","year":"1993","journal-title":"Mol Reprod Dev"},{"key":"10.1016\/j.reprotox.2006.03.018_bib22","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/S0890-6238(97)00018-X","article-title":"Toxicant-induced acceleration of epididymal sperm transit: androgen-dependent proteins may be involved","volume":"11","author":"Klinefelter","year":"1997","journal-title":"Reprod Toxicol"}],"container-title":["Reproductive Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890623806000967?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890623806000967?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:23:55Z","timestamp":1760189035000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0890623806000967"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2006,10]]}},"alternative-id":["S0890623806000967"],"URL":"https:\/\/doi.org\/10.1016\/j.reprotox.2006.03.018","relation":{},"ISSN":["0890-6238"],"issn-type":[{"type":"print","value":"0890-6238"}],"subject":[],"published":{"date-parts":[[2006,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pathogenetic transition in the morphology of abnormal sperm in the testes and the caput, corpus, and cauda epididymides of male rats after treatment with 4,6-dinitro-o-cresol","name":"articletitle","label":"Article Title"},{"value":"Reproductive Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.reprotox.2006.03.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}