{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T21:04:56Z","timestamp":1761599096788,"version":"build-2065373602"},"reference-count":37,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Reproductive Toxicology"],"published-print":{"date-parts":[[2011,1]]},"DOI":"10.1016\/j.reprotox.2010.09.014","type":"journal-article","created":{"date-parts":[[2010,10,17]],"date-time":"2010-10-17T04:27:12Z","timestamp":1287289632000},"page":"50-58","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Species- and strain-dependent teratogenicity of methanol in rabbits and mice"],"prefix":"10.1016","volume":"31","author":[{"given":"J. Nicole","family":"Sweeting","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"Siu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J.","family":"Wiley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter G.","family":"Wells","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.reprotox.2010.09.014_bib0005","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/S0890-6238(03)00013-3","article-title":"Methanol metabolism and embryotoxicity in rat and mouse conceptuses: comparisons of alcohol dehydrogenase (ADH1), formaldehyde dehydrogenase (ADH3), and catalase","volume":"17","author":"Harris","year":"2003","journal-title":"Reprod Toxicol"},{"issue":"Suppl. 1","key":"10.1016\/j.reprotox.2010.09.014_bib0010","first-page":"57","article-title":"Final report on the safety assessment of methyl alcohol","volume":"20","author":"Lanigan","year":"2001","journal-title":"Int J Toxicol"},{"issue":"3","key":"10.1016\/j.reprotox.2010.09.014_bib0015","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1093\/jat\/32.3.241","article-title":"Formic acid and methanol concentrations in death investigations","volume":"32","author":"Wallage","year":"2008","journal-title":"J Anal Toxicol"},{"issue":"6","key":"10.1016\/j.reprotox.2010.09.014_bib0020","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1002\/tera.1420490610","article-title":"Methanol-induced neural tube defects in mice: pathogenesis during neurulation","volume":"49","author":"Bolon","year":"1994","journal-title":"Teratology"},{"issue":"6","key":"10.1016\/j.reprotox.2010.09.014_bib0025","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1002\/(SICI)1096-9926(199706)55:6<364::AID-TERA2>3.0.CO;2-Y","article-title":"Critical periods of sensitivity to the developmental toxicity of inhaled methanol in the CD-1 mouse","volume":"55","author":"Rogers","year":"1997","journal-title":"Teratology"},{"issue":"4","key":"10.1016\/j.reprotox.2010.09.014_bib0030","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1002\/tera.1420510409","article-title":"Developmental toxicity of formate and formic acid in whole embryo culture: a comparative study with mouse and rat embryos","volume":"51","author":"Andrews","year":"1995","journal-title":"Teratology"},{"issue":"9","key":"10.1016\/j.reprotox.2010.09.014_bib0035","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1289\/ehp.10271","article-title":"Life-span exposure to low doses of aspartame beginning during prenatal life increases cancer effects in rats","volume":"115","author":"Soffritti","year":"2007","journal-title":"Environ Health Perspect"},{"issue":"4","key":"10.1016\/j.reprotox.2010.09.014_bib0040","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1080\/10408440802475199","article-title":"Assessment of the cancer potential of methanol","volume":"39","author":"Cruzan","year":"2009","journal-title":"Crit Rev Toxicol"},{"issue":"5","key":"10.1016\/j.reprotox.2010.09.014_bib0045","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1354\/vp.08-VP-0240-S-COM","article-title":"Mycoplasma pulmonis and lymphoma in bioassays in rats","volume":"46","author":"Schoeb","year":"2009","journal-title":"Vet Pathol"},{"issue":"4","key":"10.1016\/j.reprotox.2010.09.014_bib0050","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/0376-8716(84)90002-4","article-title":"Studies on the effect of 4-methylpyrazole on methanol poisoning using the monkey as an animal model: with particular reference to the ocular toxicity","volume":"13","author":"Blomstrand","year":"1984","journal-title":"Drug Alcohol Depend"},{"issue":"3","key":"10.1016\/j.reprotox.2010.09.014_bib0055","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/0006-2952(82)90179-4","article-title":"Role of catalase and hydroxyl radicals in the oxidation of methanol by rat liver microsomes","volume":"31","author":"Cederbaum","year":"1982","journal-title":"Biochem Pharmacol"},{"issue":"5","key":"10.1016\/j.reprotox.2010.09.014_bib0060","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/S0026-895X(25)10468-9","article-title":"Studies on the role of folic acid and folate-dependent enzymes in human methanol poisoning","volume":"31","author":"Johlin","year":"1987","journal-title":"Mol Pharmacol"},{"issue":"3","key":"10.1016\/j.reprotox.2010.09.014_bib0065","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1023\/B:CBTO.0000029466.08607.86","article-title":"Glutathione depletion modulates methanol, formaldehyde and formate toxicity in cultured rat conceptuses","volume":"20","author":"Harris","year":"2004","journal-title":"Cell Biol Toxicol"},{"issue":"1","key":"10.1016\/j.reprotox.2010.09.014_bib0070","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0273-2300(02)00031-4","article-title":"Methanol, is it a developmental risk to humans?","volume":"37","author":"Clary","year":"2003","journal-title":"Regul Toxicol Pharmacol"},{"issue":"1","key":"10.1016\/j.reprotox.2010.09.014_bib0075","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1093\/toxsci\/kfn263","article-title":"Oxidative stress in developmental origins of disease: teratogenesis, neurodevelopmental deficits, and cancer","volume":"108","author":"Wells","year":"2009","journal-title":"Toxicol Sci"},{"key":"10.1016\/j.reprotox.2010.09.014_bib0080","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.taap.2010.05.009","article-title":"Species differences in methanol and formic acid pharmacokinetics in mice, rabbits and primates","volume":"247","author":"Sweeting","year":"2010","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1016\/j.reprotox.2010.09.014_bib0085","first-page":"341","article-title":"Alcohol dehydrogenase activity in animal tissues","volume":"37","author":"Otani","year":"1978","journal-title":"Nichidai Igaku Zasshi"},{"key":"10.1016\/j.reprotox.2010.09.014_bib0090","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/0041-008X(65)90095-5","article-title":"Teratogenic effects of thalidomide in rabbits, rats, hamsters, and mice","volume":"7","author":"Fratta","year":"1965","journal-title":"Toxicol Appl Pharmacol"},{"issue":"5","key":"10.1016\/j.reprotox.2010.09.014_bib0095","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1038\/8466","article-title":"Free radical-mediated oxidative DNA damage in the mechanism of thalidomide teratogenicity","volume":"5","author":"Parman","year":"1999","journal-title":"Nat Med"},{"issue":"6","key":"10.1016\/j.reprotox.2010.09.014_bib0105","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1002\/bdrb.20178","article-title":"Species-specificity of ethylene glycol-induced developmental toxicity: toxicokinetic and whole embryo culture studies in the rabbit","volume":"83","author":"Carney","year":"2008","journal-title":"Birth Defects Res B: Dev Reprod Toxicol"},{"issue":"2","key":"10.1016\/j.reprotox.2010.09.014_bib0110","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1002\/bdrb.20003","article-title":"Methanol exposure during gastrulation causes holoprosencephaly, facial dysgenesis, and cervical vertebral malformations in C57BL\/6J mice","volume":"71","author":"Rogers","year":"2004","journal-title":"Birth Defects Res B: Dev Reprod Toxicol"},{"key":"10.1016\/j.reprotox.2010.09.014_bib0115","article-title":"Investigation of the anorectic syndrome in pregnant dutch-belted rabbits: model development","volume":"85","author":"Fernandez","year":"2009","journal-title":"Birth Defects Res A: Clin Mol Teratol"},{"issue":"7","key":"10.1016\/j.reprotox.2010.09.014_bib0120","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1002\/jps.2600820718","article-title":"Estimation of variance for AUC in animal studies","volume":"82","author":"Yuan","year":"1993","journal-title":"J Pharm Sci"},{"issue":"7","key":"10.1016\/j.reprotox.2010.09.014_bib0125","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1016\/S0891-5849(00)00203-3","article-title":"Acute methanol intoxication generates free radicals in rats: an ESR spin trapping investigation","volume":"28","author":"Kadiiska","year":"2000","journal-title":"Free Radic Biol Med"},{"year":"2003","series-title":"Pharmacology","author":"Rang","key":"10.1016\/j.reprotox.2010.09.014_bib0130"},{"issue":"6","key":"10.1016\/j.reprotox.2010.09.014_bib0135","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/S0890-6238(99)00053-2","article-title":"Differential alteration by thalidomide of the glutathione content of rat vs. rabbit conceptuses in vitro","volume":"13","author":"Hansen","year":"1999","journal-title":"Reprod Toxicol"},{"issue":"4","key":"10.1016\/j.reprotox.2010.09.014_bib0140","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1002\/bdrc.20027","article-title":"Mechanisms regulating toxicant disposition to the embryo during early pregnancy: an interspecies comparison","volume":"72","author":"Carney","year":"2004","journal-title":"Birth Defects Res C: Embryo Today"},{"key":"10.1016\/j.reprotox.2010.09.014_bib0145","series-title":"National toxicology program","article-title":"NTP-CERHR expert panel report on the reproductive and developmental toxicity of methanol","author":"NTP","year":"2002"},{"issue":"2","key":"10.1016\/j.reprotox.2010.09.014_bib0150","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1002\/bdra.20094","article-title":"Methanol, formaldehyde, and sodium formate exposure in rat and mouse conceptuses: a potential role of the visceral yolk sac in embryotoxicity","volume":"73","author":"Hansen","year":"2005","journal-title":"Birth Defects Res A: Clin Mol Teratol"},{"issue":"42","key":"10.1016\/j.reprotox.2010.09.014_bib0155","doi-asserted-by":"crossref","first-page":"35372","DOI":"10.1074\/jbc.M503991200","article-title":"Characterization of the oxidase activity in mammalian catalase","volume":"280","author":"Vetrano","year":"2005","journal-title":"J Biol Chem"},{"issue":"2","key":"10.1016\/j.reprotox.2010.09.014_bib0160","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1006\/faat.1995.1165","article-title":"Comparative toxicokinetics of inhaled methanol in the female CD-1 mouse and Sprague\u2013Dawley rat","volume":"28","author":"Perkins","year":"1995","journal-title":"Fundam Appl Toxicol"},{"issue":"1\u20132","key":"10.1016\/j.reprotox.2010.09.014_bib0165","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/BF00499291","article-title":"Purification and characterization of mouse alcohol dehydrogenase from two inbred strains that differ in total liver enzyme activity","volume":"22","author":"Rex","year":"1984","journal-title":"Biochem Genet"},{"issue":"1","key":"10.1016\/j.reprotox.2010.09.014_bib0170","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.toxlet.2009.12.012","article-title":"The role of NOX enzymes in ethanol-induced oxidative stress and apoptosis in mouse embryos","volume":"193","author":"Dong","year":"2010","journal-title":"Toxicol Lett"},{"issue":"10","key":"10.1016\/j.reprotox.2010.09.014_bib0175","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1016\/S0891-5849(01)00502-0","article-title":"Differential antioxidant enzyme activities and glutathione content between rat and rabbit conceptuses","volume":"30","author":"Hansen","year":"2001","journal-title":"Free Radic Biol Med"},{"issue":"2","key":"10.1016\/j.reprotox.2010.09.014_bib0180","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/s10067-007-0746-3","article-title":"The interrelation of glutathione reductase, catalase, glutathione peroxidase, superoxide dismutase, and glucose-6-phosphate in the pathogenesis of rheumatoid arthritis","volume":"27","author":"Kalpakcioglu","year":"2008","journal-title":"Clin Rheumatol"},{"issue":"1","key":"10.1016\/j.reprotox.2010.09.014_bib0185","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1093\/toxsci\/kfi119","article-title":"Development of a physiologically based pharmacokinetic model for ethylene glycol and its metabolite, glycolic acid, in rats and humans","volume":"85","author":"Corley","year":"2005","journal-title":"Toxicol Sci"},{"issue":"4","key":"10.1016\/j.reprotox.2010.09.014_bib0190","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/S0890-6238(01)00144-7","article-title":"(14)C methanol incorporation into DNA and proteins of organogenesis stage mouse embryos in vitro","volume":"15","author":"Huang","year":"2001","journal-title":"Reprod Toxicol"}],"container-title":["Reproductive Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890623810003114?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890623810003114?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:30:28Z","timestamp":1760189428000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0890623810003114"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,1]]}},"alternative-id":["S0890623810003114"],"URL":"https:\/\/doi.org\/10.1016\/j.reprotox.2010.09.014","relation":{},"ISSN":["0890-6238"],"issn-type":[{"type":"print","value":"0890-6238"}],"subject":[],"published":{"date-parts":[[2011,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Species- and strain-dependent teratogenicity of methanol in rabbits and mice","name":"articletitle","label":"Article Title"},{"value":"Reproductive Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.reprotox.2010.09.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}