{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T14:56:12Z","timestamp":1781967372090,"version":"3.54.5"},"reference-count":27,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Reproductive Toxicology"],"published-print":{"date-parts":[[2012,8]]},"DOI":"10.1016\/j.reprotox.2012.03.001","type":"journal-article","created":{"date-parts":[[2012,3,9]],"date-time":"2012-03-09T23:24:15Z","timestamp":1331335455000},"page":"22-30","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":33,"title":["Strain specific induction of pyometra and differences in immune responsiveness in mice exposed to 17\u03b1-ethinyl estradiol or the endocrine disrupting chemical bisphenol A"],"prefix":"10.1016","volume":"34","author":[{"given":"Jessica A.","family":"Kendziorski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric L.","family":"Kendig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin B.","family":"Gear","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott M.","family":"Belcher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.reprotox.2012.03.001_bib0005","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1002\/path.1700410104","article-title":"Leucocytic invasion as an accompaniment of epithelial metaplasia","volume":"41","author":"Burrows","year":"1935","journal-title":"J Pathol Bacteriol"},{"key":"10.1016\/j.reprotox.2012.03.001_bib0010","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1111\/j.1939-1676.2001.tb01587.x","article-title":"Breed risk of pyometra in insured dogs in Sweden","volume":"15","author":"Egenvall","year":"2001","journal-title":"J Vet Intern Med"},{"key":"10.1016\/j.reprotox.2012.03.001_bib0015","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/j.theriogenology.2006.04.023","article-title":"Canine pyometra","volume":"66","author":"Smith","year":"2006","journal-title":"Theriogenology"},{"key":"10.1016\/j.reprotox.2012.03.001_bib0020","doi-asserted-by":"crossref","first-page":"26786","DOI":"10.1155\/IDOG\/2006\/26786","article-title":"Spontaneous perforation of pyometra","author":"Yildizhan","year":"2006","journal-title":"Infect Dis Obstet Gynecol"},{"key":"10.1016\/j.reprotox.2012.03.001_bib0030","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1007\/s00335-005-0070-7","article-title":"Genetic mapping of Eutr1, a locus controlling E2-induced pyometritis in the Brown Norway rat, to RNO5","volume":"16","author":"Gould","year":"2005","journal-title":"Mamm Genome"},{"key":"10.1016\/j.reprotox.2012.03.001_bib0035","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1016\/j.theriogenology.2010.11.038","article-title":"A breed-matched case-control study of potential risk-factors for canine pyometra","volume":"75","author":"Hagman","year":"2011","journal-title":"Theriogenology"},{"key":"10.1016\/j.reprotox.2012.03.001_bib0040","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1210\/endo.140.2.6521","article-title":"Interacting quantitative trait loci control phenotypic variation in murine estradiol-regulated responses","volume":"140","author":"Roper","year":"1999","journal-title":"Endocrinology"},{"key":"10.1016\/j.reprotox.2012.03.001_bib0045","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1210\/endo-21-6-727","article-title":"Some effects of estrogens on the uterus of the mouse","volume":"21","author":"Gardner","year":"1937","journal-title":"Endocrinology"},{"key":"10.1016\/j.reprotox.2012.03.001_bib0050","first-page":"3988","article-title":"Long-term effects on the female mouse genital tract associated with prenatal exposure to diethylstilbestrol","volume":"40","author":"McLachlan","year":"1980","journal-title":"Cancer Res"},{"key":"10.1016\/j.reprotox.2012.03.001_bib0055","first-page":"773","article-title":"Neoplastic responses and correlated plasma prolactin levels in diethylstilbestrol-treated ACI and Sprague-Dawley rats","volume":"39","author":"Stone","year":"1979","journal-title":"Cancer Res"},{"key":"10.1016\/j.reprotox.2012.03.001_bib0060","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1084\/jem.63.6.789","article-title":"The effect of prolonged application of large doses of follicular hormone on the uterus of rabbits","volume":"63","author":"Zondek","year":"1936","journal-title":"J Exp Med"},{"key":"10.1016\/j.reprotox.2012.03.001_bib0065","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1289\/ehp.7534","article-title":"Urinary concentrations of bisphenol A and 4-nonylphenol in a human reference population","volume":"113","author":"Calafat","year":"2005","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.reprotox.2012.03.001_bib0070","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.reprotox.2007.06.004","article-title":"In vivo effects of bisphenol A in laboratory rodent studies","volume":"24","author":"Richter","year":"2007","journal-title":"Reprod Toxicol"},{"key":"10.1016\/j.reprotox.2012.03.001_bib0075","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1289\/ehp.1002701","article-title":"Variability of urinary concentrations of bisphenol A in spot samples, first morning voids, and 24-hour collections","volume":"119","author":"Ye","year":"2011","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.reprotox.2012.03.001_bib0080","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1289\/ehp.0110955","article-title":"The mouse uterotrophic assay: a reevaluation of its validity in assessing the estrogenicity of bisphenol A","volume":"109","author":"Markey","year":"2001","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.reprotox.2012.03.001_bib0085","first-page":"1","article-title":"Carcinogenesis bioassay of bisphenol A (CAS No. 80-05-7) in F344 rats and B6C3F1 mice (Feed Study)","volume":"215","year":"1982","journal-title":"Natl Toxicol Program Tech Rep Ser"},{"key":"10.1016\/j.reprotox.2012.03.001_bib0090","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1093\/humrep\/16.5.988","article-title":"Altered prostate growth and daily sperm production in male mice exposed prenatally to subclinical doses of 17alpha-ethinyl oestradiol","volume":"16","author":"Thayer","year":"2001","journal-title":"Hum Reprod"},{"key":"10.1016\/j.reprotox.2012.03.001_bib0095","first-page":"517","article-title":"Interstrain differences in the development of pyometra after estrogen treatment of rats","volume":"48","author":"Brossia","year":"2009","journal-title":"J Am Assoc Lab Anim Sci"},{"key":"10.1016\/j.reprotox.2012.03.001_bib0100","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1080\/15287397709529591","article-title":"Strain differences in the response of the mouse to diethylstilbestrol","volume":"3","author":"Greenman","year":"1977","journal-title":"J Toxicol Environ Health"},{"key":"10.1016\/j.reprotox.2012.03.001_bib0105","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1289\/ehp.00108243","article-title":"Strain differences in vaginal responses to the xenoestrogen bisphenol A","volume":"108","author":"Long","year":"2000","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.reprotox.2012.03.001_bib0110","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1007\/BF00840525","article-title":"Effects of estrogen on the uterus of mice of different strains","volume":"112","author":"Morozova","year":"1991","journal-title":"Biull Eksp Biol Med"},{"key":"10.1016\/j.reprotox.2012.03.001_bib0115","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1530\/REP-09-0392","article-title":"Differences in oocyte development and estradiol sensitivity among mouse strains","volume":"139","author":"Pepling","year":"2010","journal-title":"Reproduction"},{"key":"10.1016\/j.reprotox.2012.03.001_bib0120","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1126\/science.285.5431.1259","article-title":"Genetic variation in susceptibility to endocrine disruption by estrogen in mice","volume":"285","author":"Spearow","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.reprotox.2012.03.001_bib0125","first-page":"43","article-title":"The effect of estrogenic hormones on the bacterial content of the uterus","volume":"16","author":"Weinstein","year":"1943","journal-title":"Yale J Biol Med"},{"key":"10.1016\/j.reprotox.2012.03.001_bib0130","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.4049\/jimmunol.0902383","article-title":"17Beta-estradiol promotes TLR4-triggered proinflammatory mediator production through direct estrogen receptor alpha signaling in macrophages in vivo","volume":"185","author":"Calippe","year":"2010","journal-title":"J Immunol"},{"key":"10.1016\/j.reprotox.2012.03.001_bib0135","doi-asserted-by":"crossref","first-page":"7980","DOI":"10.4049\/jimmunol.180.12.7980","article-title":"Chronic estradiol administration in vivo promotes the proinflammatory response of macrophages to TLR4 activation: involvement of the phosphatidylinositol 3-kinase pathway","volume":"180","author":"Calippe","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.reprotox.2012.03.001_bib0140","first-page":"1903","article-title":"Endometrial hyperplasia and apoptosis following neonatal diethylstilbestrol exposure and subsequent estrogen stimulation in both host and transplanted hamster uteri","volume":"57","author":"Hendry","year":"1997","journal-title":"Cancer Res"}],"container-title":["Reproductive Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890623812000354?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890623812000354?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:33:02Z","timestamp":1760189582000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0890623812000354"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["S0890623812000354"],"URL":"https:\/\/doi.org\/10.1016\/j.reprotox.2012.03.001","relation":{},"ISSN":["0890-6238"],"issn-type":[{"value":"0890-6238","type":"print"}],"subject":[],"published":{"date-parts":[[2012,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Strain specific induction of pyometra and differences in immune responsiveness in mice exposed to 17\u03b1-ethinyl estradiol or the endocrine disrupting chemical bisphenol A","name":"articletitle","label":"Article Title"},{"value":"Reproductive Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.reprotox.2012.03.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}