{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T18:02:05Z","timestamp":1778349725251,"version":"3.51.4"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"special fund for agro-scientific research in the public interest of China","award":["200903056"],"award-info":[{"award-number":["200903056"]}]},{"name":"key project of Shanghai Municipal Agricultural Commission","award":["2014-2-5"],"award-info":[{"award-number":["2014-2-5"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Reproductive Toxicology"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1016\/j.reprotox.2017.11.008","type":"journal-article","created":{"date-parts":[[2017,11,20]],"date-time":"2017-11-20T20:17:56Z","timestamp":1511209076000},"page":"23-32","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Vitamin C exerts novel protective effects against cadmium toxicity in mouse spermatozoa by inducing the dephosphorylation of dihydrolipoamide dehydrogenase"],"prefix":"10.1016","volume":"75","author":[{"given":"Lirui","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peifei","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Wen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiangzhen","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linqing","family":"Zhen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jieli","family":"Fu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuhua","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sisi","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chengxiao","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinhong","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.reprotox.2017.11.008_bib0005","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1007\/s10534-004-1226-8","article-title":"Testicular toxicity induced by dietary cadmium is associated with decreased testicular zinc and increased hepatic and renal metallothionein and zinc in the bank vole (Clethrionomys glareolus)","volume":"17","author":"Bonda","year":"2004","journal-title":"Biometals"},{"key":"10.1016\/j.reprotox.2017.11.008_bib0010","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1016\/j.fct.2004.05.001","article-title":"Cadmium-induced changes in lipid peroxidation, blood hematology, biochemical parameters and semen quality of male rats: protective role of vitamin E and beta-carotene","volume":"42","author":"El-Demerdash","year":"2004","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0015","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/S1016-8478(23)13017-2","article-title":"Vitamin C and vitamin E protect the rat testes from cadmium-induced reactive oxygen species","volume":"17","author":"Sen Gupta","year":"2004","journal-title":"Mol. Cells"},{"key":"10.1016\/j.reprotox.2017.11.008_bib0020","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1002\/tox.20468","article-title":"Cadmium-induced infertility in male mice","volume":"25","author":"Monsefi","year":"2010","journal-title":"Environ. Toxicol."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0025","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1093\/humupd\/dmn004","article-title":"Oxidative stress and male infertility\u2013a clinical perspective","volume":"14","author":"Tremellen","year":"2008","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.reprotox.2017.11.008_bib0030","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1016\/S0093-691X(01)00702-6","article-title":"Reactive oxygen species-mediated loss of bovine sperm motility in egg yolk Tris extender: protection by pyruvate, metal chelators and bovine liver or oviductal fluid catalase","volume":"57","author":"Bilodeau","year":"2002","journal-title":"Theriogenology"},{"key":"10.1016\/j.reprotox.2017.11.008_bib0035","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1038\/aja.2009.78","article-title":"The protective effects of alpha-ketoacids against oxidative stress on rat spermatozoa in vitro","volume":"12","author":"Li","year":"2010","journal-title":"Asian J. Androl."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0040","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1242\/jcs.111.5.645","article-title":"A novel signal transduction cascade in capacitating human spermatozoa characterised by a redox-regulated, cAMP-mediated induction of tyrosine phosphorylation","volume":"111","author":"Aitken","year":"1998","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0045","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/S0891-5849(96)00379-6","article-title":"Regulation of protein-tyrosine phosphorylation and human sperm capacitation by reactive oxygen derivatives","volume":"22","author":"Leclerc","year":"1997","journal-title":"Free Radical Biol. Med."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0050","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/S0891-5849(00)00339-7","article-title":"Nitric oxide interacts with the cAMP pathway to modulate capacitation of human spermatozoa","volume":"29","author":"Belen Herrero","year":"2000","journal-title":"Free Radical Biol. Med."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0055","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.tox.2016.06.003","article-title":"Tyrosine phosphorylation of dihydrolipoamide dehydrogenase as a potential cadmium target and its inhibitory role in regulating mouse sperm motility","volume":"357\u2013358","author":"Li","year":"2016","journal-title":"Toxicology"},{"key":"10.1016\/j.reprotox.2017.11.008_bib0060","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1002\/ptr.3717","article-title":"The effects of rooibos (Aspalathus linearis), green tea (Camellia sinensis) and commercial rooibos and green tea supplements on epididymal sperm in oxidative stress-induced rats","volume":"26","author":"Awoniyi","year":"2012","journal-title":"Phytother. Res.: PTR"},{"key":"10.1016\/j.reprotox.2017.11.008_bib0065","doi-asserted-by":"crossref","first-page":"2759","DOI":"10.1016\/j.fct.2010.07.003","article-title":"Influence of combined treatment with zinc and selenium on cadmium induced testicular pathophysiology in rat","volume":"48","author":"Said","year":"2010","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0070","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1093\/oxfordjournals.bmb.a072625","article-title":"An introduction to free radical biochemistry","volume":"49","author":"Cheeseman","year":"1993","journal-title":"Br. Med. Bull."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0075","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.ejmech.2015.04.040","article-title":"The role of antioxidants in the chemistry of oxidative stress: a review","volume":"97","author":"Pisoschi","year":"2015","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0080","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/0014-5793(87)81456-4","article-title":"Biologically significant scavenging of the myeloperoxidase-derived oxidant hypochlorous acid by ascorbic acid. Implications for antioxidant protection in the inflamed rheumatoid joint","volume":"213","author":"Halliwell","year":"1987","journal-title":"FEBS Lett."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0085","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1007\/BF00212967","article-title":"Na+ K(+)-ATPase, glutathione, and hydroxyl free radicals in cadmium chloride-induced testicular toxicity in mice","volume":"29","author":"Shen","year":"1995","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0090","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0021-9258(19)77286-X","article-title":"The muscle phosphorylase b kinase reaction","volume":"231","author":"Krebs","year":"1958","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0095","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1016\/j.str.2004.09.013","article-title":"Molecular mechanism for regulation of the human mitochondrial branched-chain \u03b1-ketoacid dehydrogenase complex by phosphorylation","volume":"12","author":"Wynn","year":"2004","journal-title":"Structure"},{"key":"10.1016\/j.reprotox.2017.11.008_bib0100","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/B978-0-12-152827-0.50011-6","article-title":"Regulation of mammalian pyruvate and branched-chain alpha-keto acid dehydrogenase complexes by phosphorylation-dephosphorylation","volume":"27","author":"Reed","year":"1985","journal-title":"Curr. Top. Cell. Regul."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0105","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S0065-2571(96)00009-X","article-title":"Studies on the regulation of the mitochondrial alpha-ketoacid dehydrogenase complexes and their kinases","volume":"37","author":"Harris","year":"1997","journal-title":"Adv. Enzyme Regul."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0110","doi-asserted-by":"crossref","first-page":"28","DOI":"10.3109\/19396368.2013.843039","article-title":"Comparative analysis of antioxidants against cadmium induced reproductive toxicity in adult male rats","volume":"60","author":"Jahan","year":"2014","journal-title":"Syst. Biol. Reprod. Med."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0115","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.abb.2010.05.022","article-title":"Chelation of intracellular iron enhances endothelial barrier function: a role for vitamin C","volume":"500","author":"May","year":"2010","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0120","doi-asserted-by":"crossref","first-page":"2289","DOI":"10.1001\/jama.281.24.2289","article-title":"Relationship of ascorbic acid to blood lead levels","volume":"281","author":"Simon","year":"1999","journal-title":"JAMA"},{"key":"10.1016\/j.reprotox.2017.11.008_bib0125","first-page":"983","article-title":"Effect of dietary supplementation of iron and ascorbic acid on lead toxicity in rats","volume":"109","author":"Suzuki","year":"1979","journal-title":"J. Nutr."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0130","doi-asserted-by":"crossref","first-page":"1974","DOI":"10.1093\/jn\/109.11.1974","article-title":"Effectiveness of dietary iron and ascorbic acid in the prevention and cure of moderately long-term lead toxicity in rats","volume":"109","author":"Suzuki","year":"1979","journal-title":"J. Nutr."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0135","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/0024-3205(79)90215-7","article-title":"Ascorbic acid and EDTA treatment of lead toxicity in rats","volume":"24","author":"Goyer","year":"1979","journal-title":"Life Sci."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0140","doi-asserted-by":"crossref","first-page":"3313","DOI":"10.1242\/dev.120.11.3313","article-title":"Roles of heterotrimeric and monomeric G proteins in sperm-induced activation of mouse eggs","volume":"120","author":"Moore","year":"1994","journal-title":"Development"},{"key":"10.1016\/j.reprotox.2017.11.008_bib0145","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.reprotox.2015.11.001","article-title":"Hexavalent chromium affects sperm motility by influencing protein tyrosine phosphorylation in the midpiece of boar spermatozoa","volume":"59","author":"Zhen","year":"2016","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0150","doi-asserted-by":"crossref","first-page":"7977","DOI":"10.1074\/jbc.M109.085845","article-title":"Inhibition of Ser\/Thr phosphatases induces capacitation-associated signaling in the presence of Src kinase inhibitors","volume":"285","author":"Krapf","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0155","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1002\/elps.200600574","article-title":"Histochemical staining and quantification of dihydrolipoamide dehydrogenase diaphorase activity using blue native PAGE","volume":"28","author":"Yan","year":"2007","journal-title":"Electrophoresis"},{"key":"10.1016\/j.reprotox.2017.11.008_bib0160","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.mad.2008.01.006","article-title":"Changes in dihydrolipoamide dehydrogenase expression and activity during postnatal development and aging in the rat brain","volume":"129","author":"Yan","year":"2008","journal-title":"Mech. Ageing Dev."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0165","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0170","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S1642-431X(12)60093-X","article-title":"The photon emission, ATP level and motility of boar spermatozoa during liquid storage","volume":"9","author":"Gogol","year":"2009","journal-title":"Reprod. Biol."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0175","doi-asserted-by":"crossref","first-page":"1758","DOI":"10.1002\/jcp.24873","article-title":"Biphasic role of calcium in mouse sperm capacitation signaling pathways","volume":"230","author":"Navarrete","year":"2015","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0180","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1095\/biolreprod.110.088989","article-title":"Classification of mouse sperm motility patterns using an automated multiclass support vector machines model","volume":"84","author":"Goodson","year":"2011","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0185","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1080\/02652030902991649","article-title":"Cadmium accumulation in pak choi (Brassica chinensis L.) and estimated dietary intake in the suburb of Hangzhou city, China","volume":"2","author":"Yan","year":"2009","journal-title":"Food Addit. Contaminants Part B, Surveil."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0190","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/j.1749-6632.1992.tb38652.x","article-title":"Oxidants are a major contributor to aging","volume":"663","author":"Ames","year":"1992","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0195","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1080\/01480540802383200","article-title":"The role of vitamin C, vitamin E, and selenium on cadmium-induced renal toxicity of rats","volume":"31","author":"Karabulut-Bulan","year":"2008","journal-title":"Drug Chem. Toxicol."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0200","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s10534-010-9379-0","article-title":"Protective effect of ascorbic acid on cadmium-induced hypertension and vascular dysfunction in mice","volume":"24","author":"Donpunha","year":"2011","journal-title":"Biometals"},{"key":"10.1016\/j.reprotox.2017.11.008_bib0205","doi-asserted-by":"crossref","first-page":"597","DOI":"10.3109\/15376516.2012.704957","article-title":"Protective effect of ascorbic acid after single and repetitive administration of cadmium in Swiss mice","volume":"22","author":"Gren","year":"2012","journal-title":"Toxicol. Mech. Methods"},{"key":"10.1016\/j.reprotox.2017.11.008_bib0210","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.ecoenv.2016.01.029","article-title":"Effects of dietary cadmium on growth, antioxidants and bioaccumulation of sea cucumber (Apostichopus japonicus) and influence of dietary vitamin C supplementation","volume":"129","author":"Wang","year":"2016","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0215","first-page":"1401","article-title":"Ameliorative effects of Rosmarinus officinalis leaf extract and Vitamin C on cadmium-induced oxidative stress in Nile tilapia Oreochromis niloticus","volume":"36","author":"Al-Anazi","year":"2015","journal-title":"J. Environ. Biol."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0220","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/0076-6879(95)52022-8","article-title":"Dihydrolipoamide dehydrogenase: activity assays","volume":"252","author":"Patel","year":"1995","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0225","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/0003-9861(89)90309-3","article-title":"Dihydrolipoamide dehydrogenase: functional similarities and divergent evolution of the pyridine nucleotide-disulfide oxidoreductases","volume":"268","author":"Carothers","year":"1989","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0230","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.1016\/S0024-3205(01)01267-X","article-title":"Role of intracellular thiol depletion, mitochondrial dysfunction and reactive oxygen species in Salvia Miltiorrhiza-induced apoptosis in human hepatoma HepG2 cells","volume":"69","author":"Liu","year":"2001","journal-title":"Life Sci."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0235","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1007\/BF02253360","article-title":"Actions of melatonin in the reduction of oxidative stress: a review","volume":"7","author":"Reiter","year":"2000","journal-title":"J. Biomed. Sci."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0240","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1007\/s12011-015-0449-6","article-title":"The protective effects of melatonin against oxidative stress and inflammation induced by acute cadmium exposure in mice testis","volume":"170","author":"Li","year":"2016","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0245","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1111\/j.1600-079X.2010.00847.x","article-title":"Reaction mechanism of melatonin oxidation by reactive oxygen species in vitro","volume":"50","author":"Bonnefont-Rousselot","year":"2011","journal-title":"J. Pineal Res."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0250","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/1477-7827-3-67","article-title":"Reactive oxygen species in spermatozoa: methods for monitoring and significance for the origins of genetic disease and infertility","volume":"3","author":"Baker","year":"2005","journal-title":"Reprod. Biol. Endocrinol.: RB&E"},{"key":"10.1016\/j.reprotox.2017.11.008_bib0255","first-page":"327","article-title":"Determination of chelate complexes by spectrophotometry; L-ascorbic acid with cadmium (II) and zinc (II) in alkaline solution","volume":"57","author":"Kleszczewska","year":"2000","journal-title":"Acta Pol. Pharm."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0260","doi-asserted-by":"crossref","first-page":"2771","DOI":"10.2174\/092986705774462987","article-title":"Chelators as antidotes of metal toxicity: therapeutic and experimental aspects","volume":"12","author":"Blanusa","year":"2005","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0265","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1289\/ehp.8454249","article-title":"Chelation of cadmium","volume":"54","author":"Andersen","year":"1984","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0270","first-page":"103","article-title":"The role of vitamin C in iron absorption","volume":"30","author":"Hallberg","year":"1989","journal-title":"Int. J. Vit. Nutr. Res. Suppl.=Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung Supplement."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0275","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/j.theriogenology.2004.09.034","article-title":"Use of phosphoproteomics to study tyrosine kinase activity in capacitating boar sperm: kinase activity and capacitation","volume":"63","author":"Bailey","year":"2005","journal-title":"Theriogenology"},{"key":"10.1016\/j.reprotox.2017.11.008_bib0280","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1002\/(SICI)1098-2795(199811)51:3<304::AID-MRD10>3.0.CO;2-2","article-title":"Regulation of protein tyrosine phosphorylation in boar sperm through a cAMP-dependent pathway","volume":"51","author":"Kalab","year":"1998","journal-title":"Mol. Reprod. Dev."},{"key":"10.1016\/j.reprotox.2017.11.008_bib0285","first-page":"313","article-title":"The spectrophotometry determination of chelate complex: l-ascorboic acid with cuprum (II) and mercury (II) in alkaline solution","volume":"5","author":"Kleszczewska","year":"1999","journal-title":"Polish J. Environ. Studies"}],"container-title":["Reproductive Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S089062381730343X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S089062381730343X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:44:28Z","timestamp":1760190268000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S089062381730343X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":57,"alternative-id":["S089062381730343X"],"URL":"https:\/\/doi.org\/10.1016\/j.reprotox.2017.11.008","relation":{},"ISSN":["0890-6238"],"issn-type":[{"value":"0890-6238","type":"print"}],"subject":[],"published":{"date-parts":[[2018,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Vitamin C exerts novel protective effects against cadmium toxicity in mouse spermatozoa by inducing the dephosphorylation of dihydrolipoamide dehydrogenase","name":"articletitle","label":"Article Title"},{"value":"Reproductive Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.reprotox.2017.11.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}