{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T05:01:40Z","timestamp":1784869300190,"version":"3.55.0"},"reference-count":66,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Reproductive Toxicology"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1016\/j.reprotox.2021.03.004","type":"journal-article","created":{"date-parts":[[2021,3,20]],"date-time":"2021-03-20T17:51:01Z","timestamp":1616262661000},"page":"124-136","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Evaluation of post-adolescence exposure to bisphenol A on reproductive outcomes of male rodent models"],"prefix":"10.1016","volume":"101","author":[{"given":"Xiaohan","family":"Ren","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1767-2837","authenticated-orcid":false,"given":"Xinglin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tongtong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangyao","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shifeng","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0919-4660","authenticated-orcid":false,"given":"Shangqian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.reprotox.2021.03.004_bib0005","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.toxrep.2017.12.013","article-title":"Bisphenol A (BPA) the mighty and the mutagenic","volume":"5","author":"Jalal","year":"2017","journal-title":"Toxicol. Rep."},{"key":"10.1016\/j.reprotox.2021.03.004_bib0010","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1002\/jlac.19053430106","article-title":"Ueber die Einwirkung von Brom und von Chlor auf Phenole: Substitutionsprodukte, Pseudobromide und Pseudochloride","volume":"343","author":"Zincke","year":"1905","journal-title":"Justus Liebigs Annalen der Chemie"},{"key":"10.1016\/j.reprotox.2021.03.004_bib0015","series-title":"(BPA) Chemical Profile: Asia Phenol","author":"Bisphenol","year":"2016"},{"issue":"5","key":"10.1016\/j.reprotox.2021.03.004_bib0020","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1080\/10408444.2019.1621263","article-title":"Bisphenol A co-exposure effects: a key factor in understanding BPA\u2019s complex mechanism and health outcomes","volume":"49","author":"Sonavane","year":"2019","journal-title":"Crit. Rev. Toxicol."},{"key":"10.1016\/j.reprotox.2021.03.004_bib0025","series-title":"Integrated Risk Information System: Bisphenol A","author":"U.S. EPA (U.S. Environmental Protection Agency)","year":"1988"},{"key":"10.1016\/j.reprotox.2021.03.004_bib0030","series-title":"Factsheet: Scientific Opinion on Bisphenol a","author":"EFSA (European Food Safety Authority)","year":"2015"},{"key":"10.1016\/j.reprotox.2021.03.004_bib0035","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.reprotox.2015.09.006","article-title":"A review of the carcinogenic potential of bisphenol A","volume":"59","author":"Seachrist","year":"2016","journal-title":"Reprod. Toxicol."},{"issue":"4","key":"10.1016\/j.reprotox.2021.03.004_bib0040","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1016\/j.fertnstert.2016.07.1118","article-title":"Effects of bisphenol A on male and couple reproductive health: a review","volume":"106","author":"M\u00ednguez-Alarc\u00f3n","year":"2016","journal-title":"Fertil. Steril."},{"issue":"12","key":"10.1016\/j.reprotox.2021.03.004_bib0045","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1177\/0960327119862335","article-title":"Prenatal BPA and its analogs BPB, BPF, and BPS exposure and reproductive axis function in the male offspring of Sprague Dawley rats","volume":"38","author":"Ullah","year":"2019","journal-title":"Hum. Exp. Toxicol."},{"issue":"1","key":"10.1016\/j.reprotox.2021.03.004_bib0050","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1002\/tox.22211","article-title":"Acute exposure to bisphenol A and cadmium causes changes in the morphology of gerbil ventral prostates and promotes alterations in androgen-dependent proliferation and cell death","volume":"32","author":"Colleta","year":"2017","journal-title":"Environ. Toxicol."},{"issue":"1","key":"10.1016\/j.reprotox.2021.03.004_bib0055","doi-asserted-by":"crossref","first-page":"19","DOI":"10.3109\/01480545.2011.644561","article-title":"Genotoxicity and reproductive toxicity of bisphenol A and X-ray\/bisphenol A combination in male mice","volume":"36","author":"Dobrzy\u0144ska","year":"2013","journal-title":"Drug Chem. Toxicol."},{"issue":"1","key":"10.1016\/j.reprotox.2021.03.004_bib0060","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/ebm2.7","article-title":"A protocol format for the preparation, registration and publication of systematic reviews of animal intervention studies","volume":"2","author":"de Vries","year":"2015","journal-title":"Evid. Based Preclin Med."},{"issue":"7","key":"10.1016\/j.reprotox.2021.03.004_bib0065","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1000097","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"6","author":"Moher","year":"2009","journal-title":"PLoS Med."},{"issue":"1","key":"10.1016\/j.reprotox.2021.03.004_bib0070","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1258\/la.2011.011087","article-title":"A step-by-step guide to systematically identify all relevant animal studies","volume":"46","author":"Leenaars","year":"2012","journal-title":"Lab Anim."},{"key":"10.1016\/j.reprotox.2021.03.004_bib0075","article-title":"Practical methods for incorporating summary time-to-event data into meta-analysis","volume":"816","author":"Tierney","year":"2007","journal-title":"Trials"},{"key":"10.1016\/j.reprotox.2021.03.004_bib0080","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/1471-2288-14-43","article-title":"SYRCLE\u2019s risk of bias tool for animal studies","volume":"14","author":"Hooijmans","year":"2014","journal-title":"BMC Med. Res. Methodol."},{"key":"10.1016\/j.reprotox.2021.03.004_bib0085","doi-asserted-by":"crossref","first-page":"820","DOI":"10.7326\/0003-4819-127-9-199711010-00008","article-title":"Quantitative synthesis in systematic reviews","volume":"127","author":"Lau","year":"1997","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.reprotox.2021.03.004_bib0090","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"key":"10.1016\/j.reprotox.2021.03.004_bib0095","series-title":"OHAT Systematic Review","author":"NTP","year":"2015"},{"issue":"7","key":"10.1016\/j.reprotox.2021.03.004_bib0100","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1177\/0748233719862475","article-title":"Protective effect of coenzyme Q10 against bisphenol-A-induced toxicity in the rat testes","volume":"35","author":"G\u00fcle\u015f","year":"2019","journal-title":"Toxicol. Ind. Health"},{"issue":"1","key":"10.1016\/j.reprotox.2021.03.004_bib0105","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1038\/s41598-017-18869-8","article-title":"Oral exposure of low-dose bisphenol A promotes proliferation of dorsolateral prostate and induces epithelial-mesenchymal transition in aged rats","volume":"8","author":"Huang","year":"2018","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.reprotox.2021.03.004_bib0110","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1080\/10520295.2018.1493222","article-title":"Effects of folic acid on testicular toxicity induced by bisphenol-A in male Wistar rats","volume":"94","author":"Gules","year":"2019","journal-title":"Biotech. Histochem."},{"key":"10.1016\/j.reprotox.2021.03.004_bib0115","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.biopha.2018.05.125","article-title":"Melatonin ameliorates bisphenol A-induced perturbations of the prostate gland of adult Wistar rats","volume":"105","author":"Olukole","year":"2018","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.reprotox.2021.03.004_bib0120","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.biopha.2018.03.045","article-title":"Protective effect of Lespedeza cuneata ethanol extract on Bisphenol A-induced testicular dysfunction in vivo and in vitro","volume":"102","author":"Park","year":"2018","journal-title":"Biomed. Pharmacother."},{"issue":"22","key":"10.1016\/j.reprotox.2021.03.004_bib0125","doi-asserted-by":"crossref","first-page":"21635","DOI":"10.1007\/s11356-018-2229-2","article-title":"Alteration in apoptotic rate of testicular cells and sperms following administration of Bisphenol A (BPA) in Wistar albino rats","volume":"25","author":"Srivastava","year":"2018","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.reprotox.2021.03.004_bib0130","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.fct.2018.08.024","article-title":"Impact of low-dose chronic exposure to bisphenol A and its analogue bisphenol B, bisphenol F and bisphenol S on hypothalamo-pituitary-testicular activities in adult rats: a focus on the possible hormonal mode of action","volume":"121","author":"Ullah","year":"2018","journal-title":"Food Chem. Toxicol."},{"issue":"11","key":"10.1016\/j.reprotox.2021.03.004_bib0135","doi-asserted-by":"crossref","first-page":"2245","DOI":"10.1071\/RD16432","article-title":"Low doses of bisphenol A can impair postnatal testicular development directly, without affecting hormonal or oxidative stress levels","volume":"29","author":"Ogo","year":"2017","journal-title":"Reprod. Fertil. Dev."},{"issue":"1","key":"10.1016\/j.reprotox.2021.03.004_bib0140","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1093\/toxsci\/kfw070","article-title":"Bisphenol a impairs mature sperm functions by a CatSper-Relevant mechanism","volume":"152","author":"Wang","year":"2016","journal-title":"Toxicol. Sci."},{"issue":"4","key":"10.1016\/j.reprotox.2021.03.004_bib0145","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1080\/19396368.2016.1182234","article-title":"Protective effect of Cordyceps militaris extract against bisphenol A induced reproductive damage","volume":"62","author":"Wang","year":"2016","journal-title":"Syst. Biol. Reprod. Med."},{"key":"10.1016\/j.reprotox.2021.03.004_bib0150","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.jep.2016.07.033","article-title":"Echinacoside and Cistanche tubulosa (Schenk) R. Wight ameliorate bisphenol A-induced testicular and sperm damage in rats through gonad axis regulated steroidogenic enzymes","volume":"193","author":"Jiang","year":"2016","journal-title":"J. Ethnopharmacol."},{"issue":"8","key":"10.1016\/j.reprotox.2021.03.004_bib0155","doi-asserted-by":"crossref","first-page":"1977","DOI":"10.1002\/tox.22339","article-title":"Bisphenol a induces autophagy and apoptosis concurrently involving the Akt\/mTOR pathway in testes of pubertal SD rats","volume":"32","author":"Quan","year":"2017","journal-title":"Environ. Toxicol."},{"issue":"12","key":"10.1016\/j.reprotox.2021.03.004_bib0160","doi-asserted-by":"crossref","first-page":"11645","DOI":"10.1007\/s11356-016-6330-0","article-title":"Bisphenol A exposure and healing effects of Adiantum capillus-veneris L. Plant extract (APE) in bisphenol A-induced reproductive toxicity in albino rats","volume":"23","author":"Yousaf","year":"2016","journal-title":"Environ. Sci. Pollut. Res. Int."},{"issue":"3","key":"10.1016\/j.reprotox.2021.03.004_bib0165","doi-asserted-by":"crossref","first-page":"180","DOI":"10.3109\/15376516.2016.1139024","article-title":"Exposure to bisphenol A (BPA) in Wistar rats reduces sperm quality with disruption of ERK signal pathway","volume":"26","author":"Li","year":"2016","journal-title":"Toxicol. Mech. Methods"},{"issue":"11","key":"10.1016\/j.reprotox.2021.03.004_bib0170","doi-asserted-by":"crossref","first-page":"1848","DOI":"10.1177\/0748233715590758","article-title":"Oral administration of low-dose bisphenol A promotes proliferation of ventral prostate and upregulates prostaglandin D2 synthase expression in adult rats","volume":"32","author":"Wu","year":"2016","journal-title":"Toxicol. Ind. Health"},{"issue":"2","key":"10.1016\/j.reprotox.2021.03.004_bib0175","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1177\/0748233715603847","article-title":"The toxicological effects of bisphenol A and octylphenol on the reproductive system of prepubertal male rats","volume":"33","author":"Ahbab","year":"2017","journal-title":"Toxicol. Ind. Health"},{"issue":"1","key":"10.1016\/j.reprotox.2021.03.004_bib0180","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.etap.2014.09.014","article-title":"Increase in the expression of inducible nitric oxide synthase on exposure to bisphenol A: a possible cause for decline in steroidogenesis in male mice","volume":"39","author":"Chouhan","year":"2015","journal-title":"Environ. Toxicol. Pharmacol."},{"issue":"9","key":"10.1016\/j.reprotox.2021.03.004_bib0185","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1177\/0748233714561286","article-title":"Melatonin controlled apoptosis and protected the testes and sperm quality against bisphenol A-induced oxidative toxicity","volume":"32","author":"Othman","year":"2016","journal-title":"Toxicol. Ind. Health"},{"issue":"3","key":"10.1016\/j.reprotox.2021.03.004_bib0190","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/j.etap.2014.10.018","article-title":"Mitochondrion-mediated apoptosis is involved in reproductive damage caused by BPA in male rats","volume":"38","author":"Wang","year":"2014","journal-title":"Environ. Toxicol. Pharmacol."},{"issue":"2","key":"10.1016\/j.reprotox.2021.03.004_bib0195","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.toxlet.2013.03.011","article-title":"Decreased androgen receptor expression may contribute to spermatogenesis failure in rats exposed to low concentration of bisphenol A","volume":"219","author":"Qiu","year":"2013","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.reprotox.2021.03.004_bib0200","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.reprotox.2013.05.013","article-title":"Mutagenic effect of Bisphenol A on adult rat male germ cells and their fertility","volume":"40","author":"Tiwari","year":"2013","journal-title":"Reprod. Toxicol."},{"issue":"1\u20132","key":"10.1016\/j.reprotox.2021.03.004_bib0205","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.mrgentox.2013.01.005","article-title":"Melatonin ameliorates bisphenol A-induced DNA damage in the germ cells of adult male rats","volume":"752","author":"Wu","year":"2013","journal-title":"Mutat. Res."},{"issue":"2","key":"10.1016\/j.reprotox.2021.03.004_bib0210","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0055905","article-title":"Bisphenol a exposure during adulthood alters expression of aromatase and 5a-Reductase isozymes in rat prostate","volume":"8","author":"Castro","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.reprotox.2021.03.004_bib0215","doi-asserted-by":"crossref","first-page":"e676","DOI":"10.1038\/cddis.2013.203","article-title":"Exposure to bisphenol A disrupts meiotic progression during spermatogenesis in adult rats through estrogen-like activity","volume":"4","author":"Liu","year":"2013","journal-title":"Cell Death Dis."},{"issue":"2","key":"10.1016\/j.reprotox.2021.03.004_bib0220","doi-asserted-by":"crossref","first-page":"193","DOI":"10.3109\/01480540903286468","article-title":"Pro-oxidant effect of vitamin C coadministration with bisphenol A, nonylphenol, and octylphenol on the reproductive tract of male rats","volume":"33","author":"Aydo\u011fan","year":"2010","journal-title":"Drug Chem. Toxicol."},{"issue":"1\u20132","key":"10.1016\/j.reprotox.2021.03.004_bib0225","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.toxlet.2010.02.002","article-title":"Bisphenol A may cause testosterone reduction by adversely affecting both testis and pituitary systems similar to estradiol","volume":"194","author":"Nakamura","year":"2010","journal-title":"Toxicol. Lett."},{"issue":"2","key":"10.1016\/j.reprotox.2021.03.004_bib0230","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1093\/toxsci\/kfp024","article-title":"Bisphenol A exposure induces apoptosis and upregulation of Fas\/FasL and caspase-3 expression in the testes of mice","volume":"108","author":"Li","year":"2009","journal-title":"Toxicol. Sci."},{"issue":"8","key":"10.1016\/j.reprotox.2021.03.004_bib0235","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1111\/j.1432-0436.2007.00177.x","article-title":"Bisphenol A induces permanent squamous change in mouse prostatic epithelium","volume":"75","author":"Ogura","year":"2007","journal-title":"Differentiation"},{"issue":"2","key":"10.1016\/j.reprotox.2021.03.004_bib0240","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1385\/ENDO:25:2:163","article-title":"Adverse effects of environmental toxicants, octylphenol and bisphenol A, on male reproductive functions in pubertal rats","volume":"25","author":"Herath","year":"2004","journal-title":"Endocrine"},{"issue":"1\u20132","key":"10.1016\/j.reprotox.2021.03.004_bib0245","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0300-483X(02)00597-8","article-title":"Induction of oxidative stress by bisphenol A in the epididymal sperm of rats","volume":"185","author":"Chitra","year":"2003","journal-title":"Toxicology"},{"issue":"3","key":"10.1016\/j.reprotox.2021.03.004_bib0250","first-page":"203","article-title":"Effect of bisphenol A and co-administration of bisphenol A and vitamin C on epididymis of adult rats: a histological and biochemical study","volume":"5","author":"Chitra","year":"2003","journal-title":"Asian J. Androl."},{"issue":"7","key":"10.1016\/j.reprotox.2021.03.004_bib0255","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1016\/S0278-6915(03)00031-0","article-title":"Testicular toxicity of dietarily or parenterally administered bisphenol A in rats and mice","volume":"41","author":"Takahashi","year":"2003","journal-title":"Food Chem. Toxicol."},{"issue":"3","key":"10.1016\/j.reprotox.2021.03.004_bib0260","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/S0378-4274(03)00172-3","article-title":"Assessment of pubertal development in juvenile male rats after sub-acute exposure to bisphenol A and nonylphenol","volume":"143","author":"Tan","year":"2003","journal-title":"Toxicol. Lett."},{"issue":"1","key":"10.1016\/j.reprotox.2021.03.004_bib0265","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1093\/toxsci\/kfg093","article-title":"The effect on sperm production in adult Sprague-Dawley rats exposed by gavage to bisphenol A between postnatal days 91-97","volume":"74","author":"Ashby","year":"2003","journal-title":"Toxicol. Sci."},{"issue":"1\u20132","key":"10.1016\/j.reprotox.2021.03.004_bib0270","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0300-483X(02)00160-9","article-title":"Changes of serum alpha 2u-globulin in the subacute oral toxicity study of ethynyl estradiol and bisphenol A based on the draft protocol for the\u2019 enhanced OECD Test Guideline No. 407\u2019","volume":"176","author":"Yamasaki","year":"2002","journal-title":"Toxicology"},{"issue":"2","key":"10.1016\/j.reprotox.2021.03.004_bib0275","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1034\/j.1600-0722.2002.11201.x","article-title":"Effects of bisphenol A on adult male mouse fertility","volume":"110","author":"Al-Hiyasat","year":"2002","journal-title":"Eur. J. Oral Sci."},{"issue":"2","key":"10.1016\/j.reprotox.2021.03.004_bib0280","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0890-6238(02)00003-5","article-title":"Low-dose bisphenol A does not affect reproductive organs in estrogen-sensitive C57BL\/6N mice exposed at the sexually mature, juvenile, or embryonic stage","volume":"16","author":"Nagao","year":"2002","journal-title":"Reprod. Toxicol."},{"issue":"1","key":"10.1016\/j.reprotox.2021.03.004_bib0285","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1007\/s002040000204","article-title":"Testicular toxicity of dietary 2,2-bis(4-hydroxyphenyl)propane (bisphenol A) in F344 rats","volume":"75","author":"Takahashi","year":"2001","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.reprotox.2021.03.004_bib0290","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.reprotox.2013.08.008","article-title":"Bisphenol A and human health: a review of the literature","volume":"42","author":"Rochester","year":"2013","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.reprotox.2021.03.004_bib0295","first-page":"57","article-title":"Adverse effects of bisphenol A on male reproductive function","volume":"228","author":"Manfo","year":"2014","journal-title":"Rev. Environ. Contam. Toxicol."},{"key":"10.1016\/j.reprotox.2021.03.004_bib0300","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0303-7207(01)00416-6","article-title":"Effects of estrogenic compounds on human spermatozoa: evidence for interaction with anongenomic receptor for estrogen on human sperm membrane","volume":"178","author":"Luconi","year":"2021","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.reprotox.2021.03.004_bib0305","doi-asserted-by":"crossref","first-page":"110512","DOI":"10.1016\/j.ecoenv.2020.110512","article-title":"Bisphenol A affects the maturation and fertilization competence of spermatozoa","volume":"196","author":"Park","year":"2020","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.reprotox.2021.03.004_bib0310","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1002\/bdrb.21020","article-title":"Effects of transplacental 17-\u03b1-ethynyl estradiol or bisphenol A on the developmental profi le of steroidogenic acute regulatory protein in the rat testis","volume":"95","author":"Horstman","year":"2012","journal-title":"Birth Defects Res. B Dev. Reprod. Toxicol."},{"issue":"5","key":"10.1016\/j.reprotox.2021.03.004_bib0315","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1095\/biolreprod.111.095349","article-title":"The industrial chemical bisphenol A (BPA) interferes with proliferative activity and development of steroidogenic capacity in rat Leydig cells","volume":"86","author":"Nanjappa","year":"2012","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.reprotox.2021.03.004_bib0320","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1210\/en.2003-1174","article-title":"Inhibition of testicular steroidogenesis by the xenoestrogen bisphenol A is associated with reduced pituitary luteinizing hormone secretion and decreased steroidogenic enzyme gene expression in rat Leydig cells","volume":"145","author":"Akingbemi","year":"2004","journal-title":"Endocrinology"},{"issue":"7","key":"10.1016\/j.reprotox.2021.03.004_bib0325","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/j.jclinepi.2005.11.010","article-title":"Single data extraction generated more errors than double data extraction in systematic reviews","volume":"59","author":"Buscemi","year":"2006","journal-title":"J. Clin. Epidemiol."},{"issue":"2","key":"10.1016\/j.reprotox.2021.03.004_bib0330","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1177\/026119291003800208","article-title":"A gold standard publication checklist to improve the quality of animal studies, to fully integrate the three Rs, and to make systematic reviews more feasible","volume":"38","author":"Hooijmans","year":"2010","journal-title":"Altern. Lab. Anim."}],"container-title":["Reproductive Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890623821000484?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890623821000484?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:55:28Z","timestamp":1760190928000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0890623821000484"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":66,"alternative-id":["S0890623821000484"],"URL":"https:\/\/doi.org\/10.1016\/j.reprotox.2021.03.004","relation":{},"ISSN":["0890-6238"],"issn-type":[{"value":"0890-6238","type":"print"}],"subject":[],"published":{"date-parts":[[2021,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evaluation of post-adolescence exposure to bisphenol A on reproductive outcomes of male rodent models","name":"articletitle","label":"Article Title"},{"value":"Reproductive Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.reprotox.2021.03.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}