{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T01:54:10Z","timestamp":1792374850268,"version":"4.4.0"},"reference-count":120,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Reproductive Toxicology"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.reprotox.2024.108677","type":"journal-article","created":{"date-parts":[[2024,7,26]],"date-time":"2024-07-26T09:05:38Z","timestamp":1721984738000},"page":"108677","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Impact of Bisphenol A exposure on maternal gut microbial homeostasis, placental function, and fetal development during pregnancy"],"prefix":"10.1016","volume":"129","author":[{"given":"Xia","family":"Zha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mabrouk","family":"Elsabagh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongrong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yila","family":"Bai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingwen","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengzhi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.reprotox.2024.108677_bib1","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1080\/10408444.2019.1621263","article-title":"Bisphenol A co-exposure effects: a key factor in understanding BPA's complex mechanism and health outcomes","volume":"49","author":"Sonavane","year":"2019","journal-title":"Crit. Rev. Toxicol."},{"issue":"4","key":"10.1016\/j.reprotox.2024.108677_bib2","doi-asserted-by":"crossref","DOI":"10.3390\/nu12041158","article-title":"Endocrine disruptors in food: impact on gut microbiota and metabolic diseases","volume":"12","author":"G\u00e1lvez-Ontiveros","year":"2020","journal-title":"Nutrients"},{"key":"10.1016\/j.reprotox.2024.108677_bib3","article-title":"Maternal exposure to bisphenol A induces fetal growth restriction via upregulating the expression of estrogen receptors","volume":"12","author":"Cao","year":"2022","journal-title":"Chemosphere"},{"issue":"8","key":"10.1016\/j.reprotox.2024.108677_bib4","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1289\/ehp.0901716","article-title":"Urinary, circulating, and tissue biomonitoring studies indicate widespread exposure to bisphenol A","volume":"118","author":"Vandenberg","year":"2010","journal-title":"Environ. Health Persp"},{"key":"10.1016\/j.reprotox.2024.108677_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2019.108575","article-title":"The adverse health effects of bisphenol A and related toxicity mechanisms","volume":"176","author":"Ma","year":"2019","journal-title":"Environ. Res."},{"issue":"4","key":"10.1016\/j.reprotox.2024.108677_bib6","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1002\/cphy.c160038","article-title":"Adipose tissue as a site of toxin accumulation","volume":"7","author":"Jackson","year":"2017","journal-title":"Compr. Physiol."},{"issue":"3","key":"10.1016\/j.reprotox.2024.108677_bib7","doi-asserted-by":"crossref","DOI":"10.1289\/ehp.118-a116a","article-title":"Cardiovascular health: exploring a potential link between BPA and heart disease","volume":"118","author":"Lubick","year":"2010","journal-title":"Environ. Health Perspect."},{"issue":"4","key":"10.1016\/j.reprotox.2024.108677_bib8","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/j.fertnstert.2016.08.021","article-title":"Bisphenol A and ovarian steroidogenesis","volume":"106","author":"Bloom","year":"2016","journal-title":"Fertil. Steril."},{"issue":"8","key":"10.1016\/j.reprotox.2024.108677_bib9","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1210\/en.2019-00121","article-title":"CLARITY-BPA: Bisphenol A or propylthiouracil on thyroid function and effects in the developing male and female rat brain","volume":"160","author":"Bansal","year":"2019","journal-title":"Endocrinology"},{"issue":"16","key":"10.1016\/j.reprotox.2024.108677_bib10","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21165761","article-title":"Potential mechanisms of bisphenol A (BPA) contributing to human disease","volume":"21","author":"Cimmino","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.reprotox.2024.108677_bib11","doi-asserted-by":"crossref","first-page":"373","DOI":"10.3389\/fendo.2020.00373","article-title":"Effects of bisphenols on testicular steroidogenesis","volume":"11","author":"Barbagallo","year":"2020","journal-title":"Front. Endocrinol. (Lausanne)"},{"key":"10.1016\/j.reprotox.2024.108677_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2023.117385","article-title":"Endocrine disruptors: Unravelling the link between chemical exposure and Women's reproductive health","volume":"241","author":"Hassan","year":"2024","journal-title":"Environ. Res."},{"issue":"9","key":"10.1016\/j.reprotox.2024.108677_bib13","doi-asserted-by":"crossref","first-page":"4642","DOI":"10.1073\/pnas.1919563117","article-title":"Bisphenol A and bisphenol S disruptions of the mouse placenta and potential effects on the placenta-brain axis","volume":"117","author":"Mao","year":"2020","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"4","key":"10.1016\/j.reprotox.2024.108677_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajog.2010.01.025","article-title":"Transfer of bisphenol A across the human placenta","volume":"202","author":"Balakrishnan","year":"2010","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.reprotox.2024.108677_bib15","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.envpol.2017.11.074","article-title":"Dysbiosis of gut microbiota by chronic coexposure to titanium dioxide nanoparticles and bisphenol A: implications for host health in zebrafish","volume":"234","author":"Chen","year":"2018","journal-title":"Environ. Pollut."},{"issue":"5","key":"10.1016\/j.reprotox.2024.108677_bib16","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1080\/19490976.2020.1756150","article-title":"Ethnic diversity in infant gut microbiota is apparent before the introduction of complementary diets","volume":"11","author":"Xu","year":"2020","journal-title":"Gut Microbes"},{"issue":"7","key":"10.1016\/j.reprotox.2024.108677_bib17","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1007\/s00018-022-04379-y","article-title":"Maternal gut microbiota Bifidobacterium promotes placental morphogenesis, nutrient transport and fetal growth in mice","volume":"79","author":"Lopez-Tello","year":"2022","journal-title":"Cell Mol. Life Sci."},{"issue":"4","key":"10.1016\/j.reprotox.2024.108677_bib18","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1515\/reveh-2018-0059","article-title":"Epigenetic modifications associated with in utero exposure to endocrine disrupting chemicals BPA, DDT and Pb","volume":"34","author":"Onuzulu","year":"2019","journal-title":"Rev. Environ. Health"},{"key":"10.1016\/j.reprotox.2024.108677_bib19","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.coemr.2020.09.003","article-title":"Interactions between environmental exposures and the microbiome: implications for fetal programming","volume":"13","author":"Banerjee","year":"2020","journal-title":"Curr. Opin. Endocr. Metab. Res."},{"issue":"2","key":"10.1016\/j.reprotox.2024.108677_bib20","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.mce.2011.12.012","article-title":"Bisphenol-A acts as a potent estrogen via non-classical estrogen triggered pathways","volume":"355","author":"Alonso-Magdalena","year":"2012","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.reprotox.2024.108677_bib21","unstructured":"N. Division, N. Health, FDA SCIENCE BOARD SUBCOMMITTEE ON BISPHENOL A SCIENTIFIC PEER-REVIEW OF THE DRAFT ASSESSMENT OF BISPHENOL A FOR USE IN FOOD CONTACT APPLICATIONS, (2008)."},{"issue":"8","key":"10.1016\/j.reprotox.2024.108677_bib22","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1289\/ehp.7713","article-title":"An extensive new literature concerning low-dose effects of bisphenol A shows the need for a new risk assessment","volume":"113","author":"vom Saal","year":"2005","journal-title":"Environ. Health Perspect."},{"issue":"2","key":"10.1016\/j.reprotox.2024.108677_bib23","article-title":"Low-dose bisphenol a exposure: a seemingly instigating carcinogenic effect on breast cancer","volume":"4","author":"Wang","year":"2017","journal-title":"Adv. Sci. (Weinh.)"},{"issue":"Suppl 3","key":"10.1016\/j.reprotox.2024.108677_bib24","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1111\/bcpt.13125","article-title":"CLARITY-BPA academic laboratory studies identify consistent low-dose Bisphenol A effects on multiple organ systems","volume":"125","author":"Prins","year":"2019","journal-title":"Basic Clin. Pharm. Toxicol."},{"issue":"12","key":"10.1016\/j.reprotox.2024.108677_bib25","doi-asserted-by":"crossref","DOI":"10.1289\/EHP6875","article-title":"Low-dose bisphenol A in a rat model of endometrial cancer: a CLARITY-BPA study","volume":"128","author":"Leung","year":"2020","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.reprotox.2024.108677_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2021.106893","article-title":"Dose-response metabolomics and pathway sensitivity to map molecular cartography of bisphenol A exposure","volume":"158","author":"Zhao","year":"2022","journal-title":"Environ. Int"},{"issue":"6","key":"10.1016\/j.reprotox.2024.108677_bib27","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1080\/19490976.2016.1234657","article-title":"Effects of exposure to bisphenol A and ethinyl estradiol on the gut microbiota of parents and their offspring in a rodent model","volume":"7","author":"Javurek","year":"2016","journal-title":"Gut Microbes"},{"issue":"1","key":"10.1016\/j.reprotox.2024.108677_bib28","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1073\/pnas.0907697107","article-title":"Impact of oral bisphenol A at reference doses on intestinal barrier function and sex differences after perinatal exposure in rats","volume":"107","author":"Braniste","year":"2010","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"11","key":"10.1016\/j.reprotox.2024.108677_bib29","doi-asserted-by":"crossref","first-page":"4893","DOI":"10.1096\/fj.14-255380","article-title":"Food intolerance at adulthood after perinatal exposure to the endocrine disruptor bisphenol A","volume":"28","author":"Menard","year":"2014","journal-title":"Faseb J."},{"key":"10.1016\/j.reprotox.2024.108677_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.154533","article-title":"Bisphenols impact hormone levels in animals: A meta-analysis","volume":"828","author":"Rubin","year":"2022","journal-title":"Sci. Total Environ."},{"issue":"1","key":"10.1016\/j.reprotox.2024.108677_bib31","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1289\/ehp.10587","article-title":"Direct evidence revealing structural elements essential for the high binding ability of bisphenol A to human estrogen-related receptor-gamma","volume":"116","author":"Okada","year":"2008","journal-title":"Environ. Health Perspect."},{"issue":"6 Suppl","key":"10.1016\/j.reprotox.2024.108677_bib32","doi-asserted-by":"crossref","first-page":"S56","DOI":"10.1210\/en.2005-1159","article-title":"Large effects from small exposures. III. Endocrine mechanisms mediating effects of bisphenol A at levels of human exposure","volume":"147","author":"Welshons","year":"2006","journal-title":"Endocrinology"},{"key":"10.1016\/j.reprotox.2024.108677_bib33","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.chemosphere.2017.03.040","article-title":"Interactions between three typical endocrine-disrupting chemicals (EDCs) in binary mixtures exposure on myocardial differentiation of mouse embryonic stem cell","volume":"178","author":"Zhou","year":"2017","journal-title":"Chemosphere"},{"key":"10.1016\/j.reprotox.2024.108677_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2019.121488","article-title":"Hazards of bisphenol A (BPA) exposure: a systematic review of plant toxicology studies","volume":"384","author":"Xiao","year":"2020","journal-title":"J. Hazard. Mater."},{"issue":"1","key":"10.1016\/j.reprotox.2024.108677_bib35","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1677\/JOE-07-0056","article-title":"Effect of prenatal exposure to the endocrine disruptor bisphenol A on mammary gland morphology and gene expression signature","volume":"196","author":"Moral","year":"2008","journal-title":"J. Endocrinol."},{"issue":"1","key":"10.1016\/j.reprotox.2024.108677_bib36","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1021\/tx100231n","article-title":"Endocrine disrupting chemicals targeting estrogen receptor signaling: identification and mechanisms of action","volume":"24","author":"Shanle","year":"2010","journal-title":"Chem. Res. Toxicol."},{"issue":"5728","key":"10.1016\/j.reprotox.2024.108677_bib37","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1126\/science.1110591","article-title":"Diversity of the human intestinal microbial flora","volume":"308","author":"Eckburg","year":"2005","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.reprotox.2024.108677_bib38","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1038\/nrmicro3552","article-title":"Gut biogeography of the bacterial microbiota","volume":"14","author":"Donaldson","year":"2016","journal-title":"Nat. Rev. Microbiol"},{"issue":"2","key":"10.1016\/j.reprotox.2024.108677_bib39","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1124\/pr.118.015768","article-title":"Gut reactions: breaking down xenobiotic\u2013microbiome interactions","volume":"71","author":"Clarke","year":"2019","journal-title":"Pharmacol. Rev."},{"issue":"3","key":"10.1016\/j.reprotox.2024.108677_bib40","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.cell.2012.07.008","article-title":"Host remodeling of the gut microbiome and metabolic changes during pregnancy","volume":"150","author":"Koren","year":"2012","journal-title":"Cell"},{"issue":"8","key":"10.1016\/j.reprotox.2024.108677_bib41","first-page":"2214","article-title":"Connections between the gut microbiome and metabolic hormones in early pregnancy in overweight and obese women","volume":"65","author":"Callaway","year":"2016","journal-title":"Diabetes J. Am. Diabetes Assoc."},{"issue":"4","key":"10.1016\/j.reprotox.2024.108677_bib42","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1161\/HYPERTENSIONAHA.116.07910","article-title":"Increased systolic and diastolic blood pressure is associated with altered gut microbiota composition and butyrate production in early pregnancy","volume":"68","author":"Gomez-Arango","year":"2016","journal-title":"Hypertension"},{"issue":"12","key":"10.1016\/j.reprotox.2024.108677_bib43","doi-asserted-by":"crossref","first-page":"e537","DOI":"10.1542\/neo.15-12-e537","article-title":"Placental microbiome and its role in preterm birth","volume":"15","author":"Cao","year":"2014","journal-title":"Neoreviews"},{"issue":"2","key":"10.1016\/j.reprotox.2024.108677_bib44","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1093\/toxsci\/kfaa065","article-title":"The impact of environmental chemicals on the gut microbiome","volume":"176","author":"Chiu","year":"2020","journal-title":"Toxicol. Sci."},{"issue":"1","key":"10.1016\/j.reprotox.2024.108677_bib45","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1093\/toxsci\/kfab104","article-title":"Neonatal exposure to BPA, BDE-99, and PCB produces persistent changes in hepatic transcriptome associated with gut dysbiosis in adult mouse livers","volume":"184","author":"Lim","year":"2021","journal-title":"Toxicol. Sci."},{"issue":"14","key":"10.1016\/j.reprotox.2024.108677_bib46","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23148042","article-title":"Exposure to bisphenol A caused hepatoxicity and intestinal flora disorder in rats","volume":"23","author":"Liu","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"Pt A","key":"10.1016\/j.reprotox.2024.108677_bib47","article-title":"Bisphenol A increases intestinal permeability through disrupting intestinal barrier function in mice","volume":"254","author":"Feng","year":"2019","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.reprotox.2024.108677_bib48","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.lfs.2018.07.040","article-title":"Bisphenol A suppresses proliferation and induces apoptosis in colonic epithelial cells through mitochondrial and MAPK\/AKT pathways","volume":"208","author":"A","year":"2018","journal-title":"Life Sci."},{"key":"10.1016\/j.reprotox.2024.108677_bib49","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/j.envpol.2016.08.039","article-title":"Bisphenol A alters gut microbiome: Comparative metagenomics analysis","volume":"218","author":"Lai","year":"2016","journal-title":"Environ. Pollut."},{"issue":"S-1","key":"10.1016\/j.reprotox.2024.108677_bib50","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1289\/ehp.9368","article-title":"Endocrine-Disrupting Potential of Bisphenol A, Bisphenol A Dimethacrylate, 4-n-Nonylphenol, and 4-n-Octylphenol in Vitro: New Data and a Brief Review","volume":"115","author":"Bonefeld-JRgensen","year":"2007","journal-title":"Environ. Health Perspect."},{"issue":"5","key":"10.1016\/j.reprotox.2024.108677_bib51","doi-asserted-by":"crossref","DOI":"10.1128\/mSystems.00093-17","article-title":"Perinatal bisphenol A exposure induces chronic inflammation in rabbit offspring via modulation of gut bacteria and their metabolites","volume":"2","author":"Reddivari","year":"2017","journal-title":"mSystems"},{"issue":"5","key":"10.1016\/j.reprotox.2024.108677_bib52","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1038\/nrmicro.2016.17","article-title":"The microbial pharmacists within us: a metagenomic view of xenobiotic metabolism","volume":"14","author":"Spanogiannopoulos","year":"2016","journal-title":"Nat. Rev. Microbiol."},{"issue":"2","key":"10.1016\/j.reprotox.2024.108677_bib53","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1038\/nrm.2016.140","article-title":"Metabolic regulation of gene expression through histone acylations","volume":"18","author":"Sabari","year":"2017","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"1","key":"10.1016\/j.reprotox.2024.108677_bib54","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2021.1968257","article-title":"Microbiota metabolite butyrate constrains neutrophil functions and ameliorates mucosal inflammation in inflammatory bowel disease","volume":"13","author":"Li","year":"2021","journal-title":"Gut Microbes"},{"issue":"5","key":"10.1016\/j.reprotox.2024.108677_bib55","article-title":"Propionate as a health-promoting microbial metabolite in the human gut","volume":"5","author":"Elham","year":"2011","journal-title":"Nutr. Rev."},{"issue":"13","key":"10.1016\/j.reprotox.2024.108677_bib56","doi-asserted-by":"crossref","first-page":"7457","DOI":"10.1021\/es400490f","article-title":"Effect of bisphenol A on rat metabolic profiling studied by using capillary electrophoresis time-of-flight mass spectrometry","volume":"47","author":"Zeng","year":"2013","journal-title":"Environ. Sci. Technol."},{"issue":"1","key":"10.1016\/j.reprotox.2024.108677_bib57","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-15196-w","article-title":"Gut dysbiosis and impairment of immune system homeostasis in perinatally-exposed mice to Bisphenol A precede obese phenotype development","volume":"7","author":"Malais\u00e9","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.reprotox.2024.108677_bib58","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1016\/j.biopha.2019.01.007","article-title":"Bisphenol A inhibits mucin 2 secretion in intestinal goblet cells through mitochondrial dysfunction and oxidative stress","volume":"111","author":"Zhao","year":"2019","journal-title":"Biomed. Pharmacother."},{"issue":"9","key":"10.1016\/j.reprotox.2024.108677_bib59","doi-asserted-by":"crossref","first-page":"2884","DOI":"10.1128\/JCM.00845-13","article-title":"Intestinal dysbiosis and depletion of butyrogenic bacteria in clostridium difficile infection and nosocomial diarrhea","volume":"51","author":"Antharam","year":"2013","journal-title":"J. Clin. Microbiol."},{"issue":"4","key":"10.1016\/j.reprotox.2024.108677_bib60","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1264\/jsme2.ME17017","article-title":"Microbial ecology along the gastrointestinal tract","volume":"32","author":"Hillman","year":"2017","journal-title":"Microbes Environ."},{"issue":"1","key":"10.1016\/j.reprotox.2024.108677_bib61","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/s40168-024-01749-5","article-title":"Gut microbiota contributes to bisphenol A-induced maternal intestinal and placental apoptosis, oxidative stress, and fetal growth restriction in pregnant ewe model by regulating gut-placental axis","volume":"12","author":"Zhang","year":"2024","journal-title":"Microbiome"},{"issue":"5","key":"10.1016\/j.reprotox.2024.108677_bib62","first-page":"305","article-title":"The involvement of cell adhesion molecules, tight junctions, and gap junctions in human placentation","volume":"28","author":"Gorleku","year":"2020","journal-title":"Reprod. Sci."},{"key":"10.1016\/j.reprotox.2024.108677_bib63","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/112_2021_58","article-title":"The placenta as a target for alcohol during pregnancy: the close relation with IGFs signaling pathway","volume":"180","author":"Mart\u00edn-Estal","year":"2021","journal-title":"Rev. Physiol. Biochem. Pharm."},{"issue":"2","key":"10.1016\/j.reprotox.2024.108677_bib64","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.ogc.2021.02.001","article-title":"Placental function and the development of fetal overgrowth and fetal growth restriction","volume":"48","author":"Dumolt","year":"2021","journal-title":"Obstet. Gynecol. Clin. North Am."},{"issue":"6","key":"10.1016\/j.reprotox.2024.108677_bib65","first-page":"1084","article-title":"Immunity, Epigenetic perspective on the developmental effects of bisphenol A","volume":"25","author":"Kundakovic","year":"2011","journal-title":"Brain Behav."},{"issue":"1","key":"10.1016\/j.reprotox.2024.108677_bib66","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.reprotox.2010.02.007","article-title":"Placental transport and in vitro effects of Bisphenol A","volume":"30","author":"M\u00f8rck","year":"2010","journal-title":"Reprod. Toxicol."},{"issue":"4","key":"10.1016\/j.reprotox.2024.108677_bib67","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1093\/humupd\/dmaa017","article-title":"Investigation of human trophoblast invasion in vitro","volume":"26","author":"Abbas","year":"2020","journal-title":"Hum. Reprod. Update"},{"issue":"1","key":"10.1016\/j.reprotox.2024.108677_bib68","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1002\/path.1610","article-title":"Altered cell kinetics in cultured placental villous explants in pregnancies complicated by pre-eclampsia and intrauterine growth restriction","volume":"204","author":"Crocker","year":"2004","journal-title":"J. Pathol."},{"issue":"1","key":"10.1016\/j.reprotox.2024.108677_bib69","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1186\/1476-069X-10-94","article-title":"Biomonitoring of bisphenol A concentrations in maternal and umbilical cord blood in regard to birth outcomes and adipokine expression: a birth cohort study in Taiwan","volume":"10","author":"Chou","year":"2011","journal-title":"Environ. Health"},{"issue":"7","key":"10.1016\/j.reprotox.2024.108677_bib70","doi-asserted-by":"crossref","DOI":"10.3390\/nu13072426","article-title":"A systematic review of bisphenol A from dietary and non-dietary sources during pregnancy and its possible connection with fetal growth restriction: investigating its potential effects and the window of fetal vulnerability","volume":"13","author":"Vrachnis","year":"2021","journal-title":"Nutrients"},{"issue":"21","key":"10.1016\/j.reprotox.2024.108677_bib71","doi-asserted-by":"crossref","first-page":"12477","DOI":"10.1021\/es402764d","article-title":"Bisphenol-A (BPA), BPA glucuronide, and BPA sulfate in midgestation umbilical cord serum in a northern and central California population","volume":"47","author":"Gerona","year":"2013","journal-title":"Environ. Sci. Technol."},{"issue":"6","key":"10.1016\/j.reprotox.2024.108677_bib72","first-page":"1084","article-title":"Effects of BPA on female reproductive function: the involvement of epigenetic mechanism","volume":"25","author":"Santangeli","year":"2016","journal-title":"Gen. Comp. Endocrinol."},{"issue":"6","key":"10.1016\/j.reprotox.2024.108677_bib73","first-page":"8720","article-title":"Inhibitory effects of preimplantation exposure to bisphenol-A on blastocyst development and implantation","volume":"8","author":"Pan","year":"2015","journal-title":"Int J. Clin. Exp. Med"},{"key":"10.1016\/j.reprotox.2024.108677_bib74","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.envpol.2018.12.006","article-title":"In utero exposure to bisphenol A disrupts fetal testis development in rats","volume":"246","author":"Lv","year":"2019","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.reprotox.2024.108677_bib75","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3389\/fendo.2016.00007","article-title":"In utero bisphenol A exposure induces abnormal neuronal migration in the cerebral cortex of mice","volume":"7","author":"Ling","year":"2016","journal-title":"Front. Endocrinol. (Lausanne)"},{"issue":"9","key":"10.1016\/j.reprotox.2024.108677_bib76","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1289\/ehp.0901575","article-title":"Placental transfer of conjugated bisphenol A and subsequent reactivation in the rat fetus","volume":"118","author":"Nishikawa","year":"2010","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.reprotox.2024.108677_bib77","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2023.107806","article-title":"Autophagy attenuates placental apoptosis, oxidative stress and fetal growth restriction in pregnant ewes","volume":"173","author":"Zhang","year":"2023","journal-title":"Environ. Int."},{"key":"10.1016\/j.reprotox.2024.108677_bib78","doi-asserted-by":"crossref","DOI":"10.1515\/jpm-2019-0040","article-title":"Simultaneous analysis of bisphenol A fractions in maternal and fetal compartments in early second trimester of pregnancy","volume":"47","author":"Zbucka-Kr\u0119towska","year":"2019","journal-title":"J. Perinat. Med."},{"key":"10.1016\/j.reprotox.2024.108677_bib79","article-title":"Developmental programming: prenatal bisphenol A treatment disrupts mediators of placental function in sheep","volume":"243","author":"Song","year":"2019","journal-title":"Chemosphere"},{"key":"10.1016\/j.reprotox.2024.108677_bib80","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1016\/j.scitotenv.2017.10.042","article-title":"Bisphenol A distribution in serum, urine, placenta, breast milk, and umbilical cord serum in a birth panel of mother\u2013neonate pairs","volume":"626","author":"Lee","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.reprotox.2024.108677_bib81","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/978-1-4615-5913-9_19","article-title":"Fetal and perinatal influence of xenoestrogens on testis gene expression","volume":"424","author":"Saunders","year":"1997","journal-title":"Adv. Exp. Med. Biol."},{"issue":"6","key":"10.1016\/j.reprotox.2024.108677_bib82","doi-asserted-by":"crossref","first-page":"748","DOI":"10.2174\/0929867324666171009121001","article-title":"Bisphenol A in reproduction: epigenetic effects","volume":"25","author":"Chianese","year":"2018","journal-title":"Curr. Med. Chem."},{"issue":"8","key":"10.1016\/j.reprotox.2024.108677_bib83","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1093\/eurjhf\/hfq069","article-title":"The early origins of chronic heart failure: impaired placental growth and initiation of insulin resistance in childhood","volume":"12","author":"Barker","year":"2014","journal-title":"Eur. J. Heart Fail."},{"issue":"21-22","key":"10.1016\/j.reprotox.2024.108677_bib84","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1016\/j.lfs.2009.10.004","article-title":"Perinatal exposure of rats to Bisphenol A affects the fertility of male offspring","volume":"85","author":"Salian","year":"2009","journal-title":"Life Sci."},{"issue":"7","key":"10.1016\/j.reprotox.2024.108677_bib85","article-title":"Bisphenol A exposure prenatally delays bone development and bone mass accumulation in female rat offspring via the ER\u03b2\/HDAC5\/TGF\u03b2 signaling pathway","volume":"458","author":"Wang","year":"2021","journal-title":"Toxicology"},{"issue":"4","key":"10.1016\/j.reprotox.2024.108677_bib86","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1289\/ehp.5686","article-title":"Cancer and developmental exposure to endocrine disruptors","volume":"111","author":"Birnbaum","year":"2003","journal-title":"Environ. Health Perspect."},{"issue":"1-2","key":"10.1016\/j.reprotox.2024.108677_bib87","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.mce.2009.02.023","article-title":"Bisphenol A: perinatal exposure and body weight","volume":"304","author":"Beverly","year":"2009","journal-title":"Mol. Cell. Endocrinol."},{"issue":"10","key":"10.1016\/j.reprotox.2024.108677_bib88","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1289\/ehp.1204934","article-title":"Predicting later-life outcomes of early-life exposures","volume":"120","author":"Boekelheide","year":"2012","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.reprotox.2024.108677_bib89","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.chemosphere.2018.08.076","article-title":"Effects of perinatal exposure to BPA and its alternatives (BPS, BPF and BPAF) on hepatic lipid and glucose homeostasis in female mice adolescent offspring","volume":"212","author":"Meng","year":"2018","journal-title":"Chemosphere"},{"issue":"6","key":"10.1016\/j.reprotox.2024.108677_bib90","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1002\/jnr.21020","article-title":"Murine neocortical histogenesis is perturbed by prenatal exposure to low doses of Bisphenol A","volume":"84","author":"Nakamura","year":"2006","journal-title":"J. Neurosci. Res"},{"issue":"4","key":"10.1016\/j.reprotox.2024.108677_bib91","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/j.immuni.2017.04.008","article-title":"Homeostatic immunity and the microbiota","volume":"46","author":"Belkaid","year":"2017","journal-title":"Immunity"},{"issue":"6","key":"10.1016\/j.reprotox.2024.108677_bib92","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1016\/j.cell.2016.05.041","article-title":"From dietary fiber to host physiology: short-chain fatty acids as key bacterial metabolites","volume":"165","author":"Koh","year":"2016","journal-title":"Cell"},{"issue":"10","key":"10.1016\/j.reprotox.2024.108677_bib93","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1038\/nrendo.2015.128","article-title":"Short-chain fatty acids in control of body weight and insulin sensitivity","volume":"11","author":"Canfora","year":"2015","journal-title":"Nat. Rev. Endocrinol."},{"issue":"18","key":"10.1016\/j.reprotox.2024.108677_bib94","doi-asserted-by":"crossref","DOI":"10.3390\/nu14183727","article-title":"Composition of maternal circulating short-chain fatty acids in gestational diabetes mellitus and their associations with placental metabolism","volume":"14","author":"Wang","year":"2022","journal-title":"Nutrients"},{"issue":"5","key":"10.1016\/j.reprotox.2024.108677_bib95","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1080\/19490976.2017.1299847","article-title":"Maternal microbiota and antibodies as advocates of neonatal health","volume":"8","author":"Ganal-Vonarburg","year":"2017","journal-title":"Gut Microbes"},{"issue":"7384","key":"10.1016\/j.reprotox.2024.108677_bib96","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/nature10809","article-title":"Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity","volume":"482","author":"Henao-Mejia","year":"2012","journal-title":"Nature"},{"issue":"6481","key":"10.1016\/j.reprotox.2024.108677_bib97","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1126\/science.aba7673","article-title":"Maternal microbial molecules affect offspring health","volume":"367","author":"Ferguson","year":"2020","journal-title":"Science"},{"issue":"4","key":"10.1016\/j.reprotox.2024.108677_bib98","doi-asserted-by":"crossref","first-page":"352","DOI":"10.4161\/gmic.21215","article-title":"G., Microbial ecology and host-microbiota interactions during early life stages","volume":"3","author":"Collado","year":"2012","journal-title":"Gut Microbes"},{"issue":"7351","key":"10.1016\/j.reprotox.2024.108677_bib99","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1038\/nature10213","article-title":"Human nutrition, the gut microbiome and the immune system","volume":"474","author":"Kau","year":"2011","journal-title":"Nature"},{"issue":"237ra65","key":"10.1016\/j.reprotox.2024.108677_bib100","article-title":"The placenta harbors a unique microbiome","volume":"6","author":"Versalovic","year":"2014","journal-title":"Sci. Transl. Med."},{"issue":"3","key":"10.1016\/j.reprotox.2024.108677_bib101","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0090784","article-title":"Meconium microbiome analysis identifies bacteria correlated with premature birth","volume":"9","author":"Ardissone","year":"2014","journal-title":"Plos One"},{"issue":"5","key":"10.1016\/j.reprotox.2024.108677_bib102","article-title":"The gut microbiota shapes intestinal immune responses during health and disease","volume":"9","author":"Round","year":"2010","journal-title":"Nat. Rev. Drug Discov."},{"issue":"6012","key":"10.1016\/j.reprotox.2024.108677_bib103","doi-asserted-by":"crossref","DOI":"10.1126\/science.1195568","article-title":"Has the microbiota played a critical role in the evolution of the adaptive immune system?","volume":"330","author":"Lee","year":"2010","journal-title":"Science"},{"key":"10.1016\/j.reprotox.2024.108677_bib104","article-title":"Human gut colonisation may be initiated in utero by distinct microbial communities in the placenta and amniotic fluid","volume":"6","author":"Collado","year":"2016","journal-title":"Rep"},{"key":"10.1016\/j.reprotox.2024.108677_bib105","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2021.736270","article-title":"Analysis of cow-calf microbiome transfer routes and microbiome diversity in the newborn holstein dairy calf hindgut","volume":"8","author":"Zhu","year":"2021","journal-title":"Front. Nutr."},{"issue":"7769","key":"10.1016\/j.reprotox.2024.108677_bib106","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/s41586-019-1451-5","article-title":"Human placenta has no microbiome but can contain potential pathogens","volume":"572","author":"de Goffau","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.reprotox.2024.108677_bib107","doi-asserted-by":"crossref","unstructured":"Placental group B Streptococcus is associated with increased risk of adverse foetal outcome, Nat Microbiol 9(1) (2024) 15-16, https:\/\/doi.org\/10.1038\/s41564-023-01539-z.","DOI":"10.1038\/s41564-023-01539-z"},{"issue":"1","key":"10.1016\/j.reprotox.2024.108677_bib108","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1136\/jclinpath-2020-206536","article-title":"Placental microbial-metabolite profiles and inflammatory mechanisms associated with preterm birth","volume":"74","author":"Parris","year":"2021","journal-title":"J. Clin. Pathol."},{"issue":"4","key":"10.1016\/j.reprotox.2024.108677_bib109","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1007\/s00284-005-0020-3","article-title":"Isolation of commensal bacteria from umbilical cord blood of healthy neonates born by cesarean section","volume":"51","author":"Jim\u00e9nez","year":"2005","journal-title":"Curr. Microbiol."},{"key":"10.1016\/j.reprotox.2024.108677_bib110","first-page":"30","article-title":"Review: Maternal health and the placental microbiome","author":"Pelzer","year":"2016","journal-title":"Placenta"},{"issue":"1","key":"10.1016\/j.reprotox.2024.108677_bib111","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/s13073-021-01005-7","article-title":"Maternal and early life exposures and their potential to influence development of the microbiome","volume":"14","author":"Bolte","year":"2022","journal-title":"Genome Med."},{"issue":"6","key":"10.1016\/j.reprotox.2024.108677_bib112","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1161\/CIRCRESAHA.122.320771","article-title":"Gut dysbiosis promotes preeclampsia by regulating macrophages and trophoblasts","volume":"131","author":"Jin","year":"2022","journal-title":"Circ. Res."},{"issue":"6","key":"10.1016\/j.reprotox.2024.108677_bib113","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1161\/CIRCRESAHA.122.321701","article-title":"Dysbiosis in preeclampsia and treatment with short chain fatty acids","volume":"131","author":"Mackay","year":"2022","journal-title":"Circ. Res."},{"issue":"1","key":"10.1016\/j.reprotox.2024.108677_bib114","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1053\/j.gastro.2020.07.067","article-title":"The role of angiotensin converting enzyme 2 in modulating gut microbiota, intestinal inflammation, and coronavirus infection","volume":"160","author":"Penninger","year":"2021","journal-title":"Gastroenterology"},{"issue":"1","key":"10.1016\/j.reprotox.2024.108677_bib115","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-020-15126-x","article-title":"Impact of the gut microbiota on the m6A epitranscriptome of mouse cecum and liver","volume":"11","author":"Jabs","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.reprotox.2024.108677_bib116","article-title":"The gut microbiota: a major player in the toxicity of environmental pollutants?","volume":"2","author":"Claus","year":"2016","journal-title":"npj Biofilms Micro"},{"key":"10.1016\/j.reprotox.2024.108677_bib117","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1111\/nyas.12003","article-title":"Fetal programming and environmental exposures: implications for prenatal care and preterm birth","volume":"1276","author":"Schug","year":"2013","journal-title":"Ann. N. Y. Acad."},{"issue":"1","key":"10.1016\/j.reprotox.2024.108677_bib118","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.jpeds.2009.06.063","article-title":"Intestinal microbial ecology in premature infants assessed with non\u2013culture-based techniques","volume":"156","author":"Mshvildadze","year":"2010","journal-title":"J. Pediatr."},{"key":"10.1016\/j.reprotox.2024.108677_bib119","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2022.113550","article-title":"Effects of the maternal gut microbiome and gut-placental axis on melatonin efficacy in alleviating cadmium-induced fetal growth restriction","volume":"237","author":"Zhang","year":"2022","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"49","key":"10.1016\/j.reprotox.2024.108677_bib120","doi-asserted-by":"crossref","first-page":"19592","DOI":"10.1021\/acs.jafc.3c07058","article-title":"Heat stress-induced fetal intrauterine growth restriction is associated with elevated LPS levels along the maternal intestine-placenta-fetus axis in pregnant mice","volume":"71","author":"Zheng","year":"2023","journal-title":"J. Agric. Food Chem."}],"container-title":["Reproductive Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890623824001448?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890623824001448?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,4]],"date-time":"2024-09-04T01:45:36Z","timestamp":1725414336000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0890623824001448"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":120,"alternative-id":["S0890623824001448"],"URL":"https:\/\/doi.org\/10.1016\/j.reprotox.2024.108677","relation":{},"ISSN":["0890-6238"],"issn-type":[{"value":"0890-6238","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of Bisphenol A exposure on maternal gut microbial homeostasis, placental function, and fetal development during pregnancy","name":"articletitle","label":"Article Title"},{"value":"Reproductive Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.reprotox.2024.108677","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"108677"}}