{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T19:50:10Z","timestamp":1786996210173,"version":"build-2736575974"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82101676"],"award-info":[{"award-number":["82101676"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82301792"],"award-info":[{"award-number":["82301792"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFC2702600"],"award-info":[{"award-number":["2022YFC2702600"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Reproductive Toxicology"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.reprotox.2024.108758","type":"journal-article","created":{"date-parts":[[2024,11,28]],"date-time":"2024-11-28T11:47:42Z","timestamp":1732794462000},"page":"108758","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Multi-omics revealed activation of TNF-\u03b1 induced apoptosis signaling pathway in testis of DEHP treated prepubertal male rat"],"prefix":"10.1016","volume":"132","author":[{"given":"Zishui","family":"Fang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zirun","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiancheng","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaming","family":"Weng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhe","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuzhuo","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.reprotox.2024.108758_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2022.113046","article-title":"DEHP induces ferroptosis in testes via p38\u03b1-lipid ROS circulation and destroys the BTB integrity","volume":"164","author":"Yang","year":"2022","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.reprotox.2024.108758_bib2","doi-asserted-by":"crossref","unstructured":"Lagos-Cabr\u00e9 R., Moreno R.D. Contribution of environmental pollutants to male infertily: a working model of germ cell apoptosis induced by plasticizers. 2012.","DOI":"10.4067\/S0716-97602012000100001"},{"key":"10.1016\/j.reprotox.2024.108758_bib3","doi-asserted-by":"crossref","unstructured":"Tang X., Wu S.A.-O.X., Shen L., Wei Y., Cao X., Wang Y., et al. Di-(2-ethylhexyl) phthalate (DEHP)-induced testicular toxicity through Nrf2-mediated Notch1 signaling pathway in Sprague-Dawley rats. 2018.","DOI":"10.1002\/tox.22559"},{"key":"10.1016\/j.reprotox.2024.108758_bib4","doi-asserted-by":"crossref","unstructured":"Radke E.G., Braun J.M., Meeker J.D., Cooper G.S.. Phthalate exposure and male reproductive outcomes: A systematic review of the human epidemiological evidence. 2019.","DOI":"10.1016\/j.envint.2019.02.003"},{"key":"10.1016\/j.reprotox.2024.108758_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2021.112326","article-title":"Stereological analysis and transcriptome profiling of testicular injury induced by di-(2-ethylhexyl) phthalate in prepubertal rats","volume":"220","author":"Han","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.reprotox.2024.108758_bib6","doi-asserted-by":"crossref","unstructured":"Zhao T.X., Wang J.K., Shen L.J., Long C.L., Liu B., Wei Y., et al. Increased m6A RNA modification is related to the inhibition of the Nrf2-mediated antioxidant response in di-(2-ethylhexyl) phthalate-induced prepubertal testicular injury. 2020.","DOI":"10.1016\/j.envpol.2020.113911"},{"key":"10.1016\/j.reprotox.2024.108758_bib7","doi-asserted-by":"crossref","unstructured":"Wang J., Zhao T., Chen J., Kang L., Wei Y., Wu Y., et al. Multiple transcriptomic profiling: p53 signaling pathway is involved in DEHP-induced prepubertal testicular injury via promoting cell apoptosis and inhibiting cell proliferation of Leydig cells. 2021.","DOI":"10.1016\/j.jhazmat.2020.124316"},{"key":"10.1016\/j.reprotox.2024.108758_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2008.08.009","article-title":"Mechanisms of action of phthalate esters, individually and in combination, to induce abnormal reproductive development in male laboratory rats","author":"Howdeshell","year":"2008","journal-title":"Environ. Res."},{"key":"10.1016\/j.reprotox.2024.108758_bib9","doi-asserted-by":"crossref","DOI":"10.1093\/toxsci\/kfr146","article-title":"Dose-response assessment of fetal testosterone production and gene expression levels in rat testes following in utero exposure to diethylhexyl phthalate, diisobutyl phthalate, diisoheptyl phthalate, and diisononyl phthalate","author":"Hannas","year":"2011","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.reprotox.2024.108758_bib10","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1210\/en.2017-03004","article-title":"Prenatal Exposure to Di(2-Ethylhexyl) phthalate causes long-term transgenerational effects on female reproduction in mice","volume":"159","author":"Brehm","year":"2018","journal-title":"Endocrinology"},{"key":"10.1016\/j.reprotox.2024.108758_bib11","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1053\/jpsu.2000.19249","article-title":"Polyvinylchloride infusion lines expose infants to large amounts of toxic plasticizers","volume":"35","author":"Loff","year":"2000","journal-title":"J. Pediatric Surg."},{"key":"10.1016\/j.reprotox.2024.108758_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2020.109428","article-title":"Biomonitoring of Bis(2-ethylhexyl)phthalate (DEHP) in Italian children and adolescents: data from LIFE PERSUADED project","volume":"185","author":"Tait","year":"2020","journal-title":"Environ. Res."},{"key":"10.1016\/j.reprotox.2024.108758_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2008.08.007","article-title":"Environmental phthalate exposure in relation to reproductive outcomes and other health endpoints in humans","author":"Swan","year":"2008","journal-title":"Environ. Res."},{"key":"10.1016\/j.reprotox.2024.108758_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2019.105287","article-title":"Ordinal dose-response modeling approach for the phthalate syndrome","author":"Blessinger","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.reprotox.2024.108758_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2019.04.040","article-title":"Phthalate exposure and metabolic effects: a systematic review of the human epidemiological evidence","volume":"132","author":"Radke","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.reprotox.2024.108758_bib16","doi-asserted-by":"crossref","first-page":"3183","DOI":"10.1007\/s00204-019-02590-8","article-title":"Transcriptome analysis revealed the mechanism of the metabolic toxicity and susceptibility of di-(2-ethylhexyl)phthalate on adolescent male ICR mice with type 2 diabetes mellitus","volume":"93","author":"Ding","year":"2019","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.reprotox.2024.108758_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2019.121534","article-title":"Prenatal low-dose DEHP exposure induces metabolic adaptation and obesity: Role of hepatic thiamine metabolism","volume":"385","author":"Fan","year":"2020","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.reprotox.2024.108758_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.156815","article-title":"Di-(2-ethylhexyl) phthalate increases plasma glucose and induces lipid metabolic disorders via FoxO1 in adult mice","volume":"842","author":"Wei","year":"2022","journal-title":"Sci. TOTAL Environ."},{"key":"10.1016\/j.reprotox.2024.108758_bib19","doi-asserted-by":"crossref","first-page":"12812","DOI":"10.1021\/acs.est.9b04369","article-title":"DEHP and DINP induce tissue- and gender-specific disturbances in fatty acid and lipidomic profiles in neonatal mice: a comparative study","volume":"53","author":"Huang","year":"2019","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.reprotox.2024.108758_bib20","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jchromb.2016.05.009","article-title":"Application of metabolomics to investigate the antitumor mechanism of flavopiridol in MCF-7 breast cancer cells","volume":"1025","author":"Shao","year":"2016","journal-title":"J. Chromatogr. B-Anal. Technol. Biomed. LIFE Sci."},{"key":"10.1016\/j.reprotox.2024.108758_bib21","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.aca.2018.03.058","article-title":"A targeted metabolomics approach for clinical diagnosis of inborn errors of metabolism","volume":"1025","author":"Jacob","year":"2018","journal-title":"Analytica Chim. ACTA"},{"key":"10.1016\/j.reprotox.2024.108758_bib22","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/j.foodchem.2018.07.061","article-title":"NMR-based global metabolomics approach to decipher the metabolic effects of three plant growth regulators on strawberry maturation","volume":"269","author":"An","year":"2018","journal-title":"Food Chem."},{"key":"10.1016\/j.reprotox.2024.108758_bib23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ecoenv.2018.07.027","article-title":"Toxicity and metabolomics study of isocarbophos in adult zebrafish","volume":"163","author":"Jia","year":"2018","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.reprotox.2024.108758_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.126865","article-title":"A comprehensive analysis of metabolomics and transcriptomics reveals new biomarkers and mechanistic insights on DEHP exposures in MCF-7 cells","volume":"255","author":"Lu","year":"2020","journal-title":"Chemosphere"},{"key":"10.1016\/j.reprotox.2024.108758_bib25","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1002\/tox.24029","article-title":"Protective effects of melatonin on DEHP-induced apoptosis and oxidative stress in prepubertal testes via the PI3K\/AKT pathway","volume":"39","author":"Chen","year":"2024","journal-title":"Environ. Toxicol."},{"key":"10.1016\/j.reprotox.2024.108758_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2020.113911","article-title":"Increased m6A RNA modification is related to the inhibition of the Nrf2-mediated antioxidant response in di-(2-ethylhexyl) phthalate-induced prepubertal testicular injury","volume":"259","author":"Zhao","year":"2020","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.reprotox.2024.108758_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.taap.2020.115151","article-title":"The role of STAT3\/p53 and PI3K-Akt-mTOR signaling pathway on DEHP-induced reproductive toxicity in pubertal male rat","author":"Fu","year":"2020","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.reprotox.2024.108758_bib28","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.freeradbiomed.2024.02.006","article-title":"Roles of ferroptosis in type 1 diabetes induced spermatogenic dysfunction","volume":"214","author":"Cao","year":"2024","journal-title":"FREE Radic. Biol. Med."},{"key":"10.1016\/j.reprotox.2024.108758_bib29","doi-asserted-by":"crossref","DOI":"10.1186\/s40168-023-01659-y","article-title":"The gut metabolite 3-hydroxyphenylacetic acid rejuvenates spermatogenic dysfunction in aged mice through GPX4-mediated ferroptosis","volume":"11","author":"Jin","year":"2023","journal-title":"Microbiome"},{"key":"10.1016\/j.reprotox.2024.108758_bib30","doi-asserted-by":"crossref","first-page":"16","DOI":"10.3945\/ajcn.113.058743","article-title":"Gut microbiota after gastric bypass in human obesity: increased richness and associations of bacterial genera with adipose tissue genes","volume":"98","author":"Kong","year":"2013","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.reprotox.2024.108758_bib31","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1038\/ismej.2013.223","article-title":"Longitudinal study of murine microbiota activity and interactions with the host during acute inflammation and recovery","volume":"8","author":"Schwab","year":"2014","journal-title":"Isme J."},{"key":"10.1016\/j.reprotox.2024.108758_bib32","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gkaa970","article-title":"KEGG: integrating viruses and cellular organisms","volume":"49","author":"Kanehisa","year":"2021","journal-title":"NUCLEIC ACIDS Res."},{"key":"10.1016\/j.reprotox.2024.108758_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2023.121957","article-title":"Phthalate exposure and the metabolic syndrome: a systematic review and meta","volume":"333","author":"Merida","year":"2023","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.reprotox.2024.108758_bib34","first-page":"346","article-title":"The necroptosis-mediated imbalance of mitochondrial dynamics is involved in DEHP-induced toxicity to immature testes via the PGAM5-DRP1 interaction (vol 346, 123585, 2024)","author":"Zhou","year":"2024","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.reprotox.2024.108758_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2022.102584","article-title":"Ferroptosis is critical for phthalates driving the blood-testis barrier dysfunction via targeting transferrin receptor","volume":"59","author":"Zhao","year":"2023","journal-title":"REDOX Biol."},{"key":"10.1016\/j.reprotox.2024.108758_bib36","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1177\/0748233714561286","article-title":"Melatonin controlled apoptosis and protected the testes and sperm quality against bisphenol A-induced oxidative toxicity","volume":"32","author":"Othman","year":"2016","journal-title":"Toxicol. Ind. HEALTH"},{"key":"10.1016\/j.reprotox.2024.108758_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2021.112889","article-title":"Exposure to DEHP induces testis toxicity and injury through the ROS\/ mTOR\/NLRP3 signaling pathway in immature rats","volume":"227","author":"Hong","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.reprotox.2024.108758_bib38","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.jsbmb.2018.07.005","article-title":"SIRT2 plays a novel role on progesterone, estradiol and testosterone synthesis via PPARs\/LXR\u03b1 pathways in bovine ovarian granular cells","volume":"185","author":"Xu","year":"2019","journal-title":"J. STEROID Biochem. Mol. Biol."},{"key":"10.1016\/j.reprotox.2024.108758_bib39","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.lfs.2018.06.009","article-title":"Lycopene abrogates di-(2-ethylhexyl) phthalate induced testicular injury by modulating oxidative, endocrine and inflammatory changes in mice","volume":"207","author":"Bahrami","year":"2018","journal-title":"Life Sci."},{"key":"10.1016\/j.reprotox.2024.108758_bib40","article-title":"Comprehensive transcriptome and metabolome profiling reveal metabolic mechanisms of Nitraria sibirica Pall. to salt stress","volume":"11","author":"Li","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.reprotox.2024.108758_bib41","doi-asserted-by":"crossref","first-page":"5056","DOI":"10.1021\/acs.jafc.7b01015","article-title":"Di(2-ethylhexyl)phthalate alters the synthesis and \u03b2-oxidation of fatty acids and hinders ATP supply in mouse testes via UPLC-Q-exactive orbitrap MS-based metabonomics study","volume":"65","author":"Shen","year":"2017","journal-title":"J. Agric. FOOD Chem."},{"key":"10.1016\/j.reprotox.2024.108758_bib42","article-title":"m6A contributes to a pro-survival state in GC-2 cells by facilitating DNA damage repair: novel perspectives on the mechanism underlying DEHP genotoxicity in male germ cells","author":"Fu","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.reprotox.2024.108758_bib43","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1008529","article-title":"Environmentally-relevant exposure to diethylhexyl phthalate (DEHP) alters regulation of double-strand break formation and crossover designation leading to germline dysfunction in caenorhabditis elegans","author":"Cuenca","year":"2020","journal-title":"PLOS Genet"},{"key":"10.1016\/j.reprotox.2024.108758_bib44","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1111\/jfd.13393","article-title":"Functional characterization of TNF-\u03b1 in pufferfish (Takifugu obscurus) in immune response and apoptosis against Aeromonas hydrophila","volume":"44","author":"Kong","year":"2021","journal-title":"J. Fish Dis."},{"key":"10.1016\/j.reprotox.2024.108758_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2023.109223","article-title":"Quercetin alleviates DEHP exposure-induced pyroptosis and cytokine expression changes in grass carp L8824 cell line by inhibiting ROS\/MAPK\/ NF-\u03baB pathway.","volume":"143","author":"Cai","year":"2023","journal-title":"Fish Shellfish Immunology"},{"key":"10.1016\/j.reprotox.2024.108758_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2023.108995","article-title":"Evodiamine alleviates DEHP-induced hepatocyte pyroptosis, necroptosis and immunosuppression in grass carp through ROS-regulated TLR4\/MyD88\/NF-\u03baB pathway.","volume":"140","author":"Lei","year":"2023","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.reprotox.2024.108758_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2021.129740","article-title":"Exposure to phthalates DEHP and DINP May lead to oxidative damage and lipidomic disruptions in mouse kidney","volume":"271","author":"Gu","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.reprotox.2024.108758_bib48","doi-asserted-by":"crossref","DOI":"10.1177\/09603271221139444","article-title":"Transcriptomic and proteomic characteristics of the di(2-ethylhexyl) phthalate-induced sperm dna damage mouse model","volume":"41","author":"Zhang","year":"2022","journal-title":"Hum. Exp. Toxicol."},{"key":"10.1016\/j.reprotox.2024.108758_bib49","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.fct.2018.12.010","article-title":"Di-2-ethylhexylphthalate promotes thyroid cell proliferation and DNA damage through activating thyrotropin-receptor-mediated pathways in vitro and in vivo","volume":"124","author":"Kim","year":"2019","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.reprotox.2024.108758_bib50","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.oraloncology.2011.10.001","article-title":"S100A14 inhibits proliferation of oral carcinoma derived cells through G1-arrest","volume":"48","author":"Sapkota","year":"2012","journal-title":"Oral. Oncol."},{"key":"10.1016\/j.reprotox.2024.108758_bib51","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0019375","article-title":"S100A14 stimulates cell proliferation and induces cell apoptosis at different concentrations via receptor for advanced glycation end products (RAGE)","volume":"6","author":"Jin","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.reprotox.2024.108758_bib52","doi-asserted-by":"crossref","first-page":"17109","DOI":"10.1074\/jbc.M111.326975","article-title":"Involvement of S100A14 protein in cell invasion by affecting expression and function of matrix metalloproteinase (MMP)-2 via p53-dependent Transcriptional Regulation","volume":"287","author":"Chen","year":"2012","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.reprotox.2024.108758_bib53","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1248\/bpb.25.1446","article-title":"Taraxinic acid, a hydrolysate of sesquiterpene lactone glycoside from the Taraxacum coreanum NAKAI, induces the differentiation of human acute promyelocytic leukemia HL-60 cells","volume":"25","author":"Choi","year":"2002","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.reprotox.2024.108758_bib54","doi-asserted-by":"crossref","DOI":"10.1007\/s12032-021-01577-9","article-title":"The apoptotic efficacy of succinic acid on renal cancer cell lines","volume":"38","author":"Kasarci","year":"2021","journal-title":"Med. Oncol."},{"key":"10.1016\/j.reprotox.2024.108758_bib55","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1097\/QAI.0000000000001911","article-title":"S100A14 is increased in activated NK cells and plasma of HIV-exposed seronegative people who inject drugs and promotes monocyte-NK crosstalk","volume":"80","author":"Colon","year":"2019","journal-title":"Jaids-J. Acquir. Immune Defic.\u00a0Syndr."},{"key":"10.1016\/j.reprotox.2024.108758_bib56","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1126\/science.abh2841","article-title":"Tumor necrosis factor induces pathogenic mitochondrial ROS in tuberculosis through reverse electron transport","volume":"376","author":"Roca","year":"2022","journal-title":"Science"},{"key":"10.1016\/j.reprotox.2024.108758_bib57","doi-asserted-by":"crossref","first-page":"4930","DOI":"10.1182\/blood-2013-02-486217","article-title":"Mast cell and macrophage chemokines CXCL1\/CXCL2 control the early stage of neutrophil recruitment during tissue inflammation","volume":"121","author":"De Filippo","year":"2013","journal-title":"Blood"},{"key":"10.1016\/j.reprotox.2024.108758_bib58","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1038\/aps.2013.182","article-title":"TNF-\u03b1 induces CXCL1 chemokine expression and release in human vascular endothelial cells in vitro via two distinct signaling pathways","volume":"35","author":"Lo","year":"2014","journal-title":"Acta Pharmacologica Sin."},{"key":"10.1016\/j.reprotox.2024.108758_bib59","doi-asserted-by":"crossref","first-page":"25481","DOI":"10.1074\/jbc.M301403200","article-title":"Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation","volume":"278","author":"Le Poul","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.reprotox.2024.108758_bib60","doi-asserted-by":"crossref","DOI":"10.1177\/09603271221135064","article-title":"ARL4C depletion suppresses the resistance of ovarian cancer to carboplatin by disrupting cholesterol transport and autophagy via Notch-RBP-J\u03ba-H3K4Me3-OSBPL5.","volume":"41","author":"Yang","year":"2022","journal-title":"Hum. Exp. Toxicol."},{"key":"10.1016\/j.reprotox.2024.108758_bib61","doi-asserted-by":"crossref","DOI":"10.1016\/j.dib.2019.104526","article-title":"Data the DEHP induced changes on the trace element and mineral levels in the brain and testis tissues of rats","author":"Aydemir","year":"2019","journal-title":"Data Brief"}],"container-title":["Reproductive Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890623824002259?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890623824002259?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T02:32:34Z","timestamp":1751509954000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0890623824002259"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":61,"alternative-id":["S0890623824002259"],"URL":"https:\/\/doi.org\/10.1016\/j.reprotox.2024.108758","relation":{},"ISSN":["0890-6238"],"issn-type":[{"value":"0890-6238","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multi-omics revealed activation of TNF-\u03b1 induced apoptosis signaling pathway in testis of DEHP treated prepubertal male rat","name":"articletitle","label":"Article Title"},{"value":"Reproductive Toxicology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.reprotox.2024.108758","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"108758"}}