{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T12:34:53Z","timestamp":1766579693975,"version":"3.40.5"},"reference-count":30,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100014423","name":"Environmental Restoration and Conservation Agency of Japan","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100014423","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","respiratoryinvestigation.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Investigation"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.resinv.2018.05.004","type":"journal-article","created":{"date-parts":[[2018,6,13]],"date-time":"2018-06-13T23:33:05Z","timestamp":1528932785000},"page":"392-398","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Changes in the breath sound spectrum with bronchodilation in children with asthma"],"prefix":"10.1016","volume":"56","author":[{"given":"Mariko","family":"Nukaga","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideyuki","family":"Tabata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayumi","family":"Enseki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kota","family":"Hirai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Furuya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiko","family":"Kato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5273-1820","authenticated-orcid":false,"given":"Hiroyuki","family":"Mochizuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.resinv.2018.05.004_bib1","unstructured":"Global Initiative for Asthma. Global strategy for asthma management and prevention. Available at \u3008http:\/\/ginasthma.org\/archived-reports\/\u3009. [Accessed 27 March 2017]."},{"key":"10.1016\/j.resinv.2018.05.004_bib2","unstructured":"Japanese Society of Pediatric Allergy and Clinical Immunology. Guidelines for the treatment and management of pediatric bronchial asthma 2012 (Japanese). Tokyo: Kyowa Kikaku, 2011."},{"key":"10.1016\/j.resinv.2018.05.004_bib3","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1378\/chest.111.6.1519","article-title":"Measurement of respiratory resistance in the emergency department: feasibility in young children with acute asthma","volume":"111","author":"Ducharme","year":"1997","journal-title":"Chest"},{"key":"10.1016\/j.resinv.2018.05.004_bib4","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1183\/09031936.03.00036302","article-title":"Wheeze monitoring in children for assessment of nocturnal asthma and response to therapy","volume":"21","author":"Bentur","year":"2003","journal-title":"Eur Respir J"},{"key":"10.1016\/j.resinv.2018.05.004_bib5","doi-asserted-by":"crossref","first-page":"373","DOI":"10.2332\/allergolint.12-RAI-0440","article-title":"Forced oscillation technique and childhood asthma","volume":"61","author":"Mochizuki","year":"2012","journal-title":"Allergol Int"},{"key":"10.1016\/j.resinv.2018.05.004_bib6","first-page":"171","article-title":"Forced oscillation technique. Reference values for resistance and reactance over a frequency spectrum of 2-26 Hz in healthy children aged 2.3-12.5 years","volume":"21","author":"Duiverman","year":"1985","journal-title":"Bull Eur Physiopathol Respir"},{"key":"10.1016\/j.resinv.2018.05.004_bib7","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1378\/chest.126.4.1060","article-title":"Adenosine bronchial provocation with computerized wheeze detection in young infants with prolonged cough","volume":"126","author":"Bentur","year":"2004","journal-title":"Chest"},{"key":"10.1016\/j.resinv.2018.05.004_bib8","doi-asserted-by":"crossref","first-page":"153","DOI":"10.4103\/2319-4170.137773","article-title":"An alternative respiratory sounds classification system utilizing artificial neural networks","volume":"38","author":"Oweis","year":"2015","journal-title":"Biomed J"},{"key":"10.1016\/j.resinv.2018.05.004_bib9","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.resinv.2015.07.002","article-title":"A novel method for detecting airway narrowing using breath sound spectrum analysis in children","volume":"54","author":"Tabata","year":"2016","journal-title":"Respir Invest"},{"key":"10.1016\/j.resinv.2018.05.004_bib10","doi-asserted-by":"crossref","DOI":"10.1111\/resp.13109","article-title":"Treatment evaluation using lung sound analysis in asthmatic children","author":"Habukawa","year":"2017","journal-title":"Respirology"},{"key":"10.1016\/j.resinv.2018.05.004_bib11","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.resinv.2016.11.005","article-title":"A clinical method for detecting bronchial reversibility using a breath sound spectrum analysis in infants","volume":"55","author":"Enseki","year":"2017","journal-title":"Respir Invest"},{"key":"10.1016\/j.resinv.2018.05.004_bib12","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1164\/ajrccm\/141.5_Pt_1.1147","article-title":"Variation of breath sound and airway caliber induced by histamine challenge","volume":"141","author":"Anderson","year":"1990","journal-title":"Am Rev Respir Dis"},{"key":"10.1016\/j.resinv.2018.05.004_bib13","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1164\/ajrccm\/137.4.872","article-title":"Airflow and normal lung sounds","volume":"137","author":"Shykoff","year":"1988","journal-title":"Am Rev Respir Dis"},{"key":"10.1016\/j.resinv.2018.05.004_bib14","article-title":"Changes in the breath sound spectrum during methacholine inhalation in children with asthma","author":"Tabata","year":"2017","journal-title":"Respirology"},{"key":"10.1016\/j.resinv.2018.05.004_bib15","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1378\/chest.116.3.619","article-title":"Difference in airway reactivity in children with atopic vs nonatopic asthma","volume":"116","author":"Mochizuki","year":"1999","journal-title":"Chest"},{"key":"10.1016\/j.resinv.2018.05.004_bib16","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1002\/ppul.1068","article-title":"Relationship between bronchial hyperresponsiveness and development of asthma in children with chronic cough","volume":"31","author":"Nishimura","year":"2001","journal-title":"Pediatr Pulmonol"},{"key":"10.1016\/j.resinv.2018.05.004_bib17","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1378\/chest.100.4.999","article-title":"Frequency spectra of normal breath sounds in childhood","volume":"100","author":"Hidalgo","year":"1991","journal-title":"Chest"},{"key":"10.1016\/j.resinv.2018.05.004_bib18","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.1152\/jappl.1990.69.6.2126","article-title":"Transfer function of sound transmission in subglottal human respiratory system at low frequencies","volume":"69","author":"Wodicka","year":"1990","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.resinv.2018.05.004_bib19","first-page":"481","article-title":"Measurement and theory of wheezing breath sounds","volume":"57","author":"Gavriely","year":"1984","journal-title":"J Appl Physiol Respir Environ Exerc Physiol"},{"key":"10.1016\/j.resinv.2018.05.004_bib20","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1111\/j.1440-1843.2008.01465.x","article-title":"High-pitched breath sounds indicate airflow limitation in asymptomatic asthmatic children","volume":"14","author":"Habukawa","year":"2009","journal-title":"Respirology"},{"key":"10.1016\/j.resinv.2018.05.004_bib21","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1136\/thx.47.9.680","article-title":"Effect of methacholine induced bronchoconstriction on the spectral characteristics of breath sounds in asthma","volume":"47","author":"Spence","year":"1992","journal-title":"Thorax"},{"key":"10.1016\/j.resinv.2018.05.004_bib22","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1378\/chest.102.3.759","article-title":"Histamine challenge in young children using computerized loung sounds analysis","volume":"102","author":"Beck","year":"1992","journal-title":"Chest"},{"key":"10.1016\/j.resinv.2018.05.004_bib23","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1378\/chest.109.5.1283","article-title":"Averaged and time-gated spectral analysis of respiratory sounds. Repeatability of spectral parameters in healthy men and in patients with fibrosing alveolitis","volume":"109","author":"Sovij\u00e4rvi","year":"1996","journal-title":"Chest"},{"key":"10.1016\/j.resinv.2018.05.004_bib24","article-title":"A lung sound analysis in a child thought to have cough variant asthma: a case report","author":"Imai","year":"2017","journal-title":"Allergol Int"},{"key":"10.1016\/j.resinv.2018.05.004_bib25","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.cmpb.2016.10.025","article-title":"Enhancement of lung sounds based on empirical mode decomposition and Fourier transform algorithm","volume":"139","author":"Mondal","year":"2017","journal-title":"Comput Methods Prog Biomed"},{"key":"10.1016\/j.resinv.2018.05.004_bib26","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1111\/j.1440-1843.2010.01706.x","article-title":"Changes in the highest frequency of breath sounds without wheezing during methacholine inhalation challenge in children","volume":"15","author":"Habukawa","year":"2010","journal-title":"Respirology"},{"key":"10.1016\/j.resinv.2018.05.004_bib27","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.alit.2016.03.010","article-title":"Changes in lung sounds during asthma progression in a guinea pig model","volume":"65","author":"Habukawa","year":"2016","journal-title":"Allergol Int"},{"key":"10.1016\/j.resinv.2018.05.004_bib28","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.compbiomed.2016.01.002","article-title":"Wheezing recognition algorithm using recordings of respiratory sounds at the mouth in a pediatric population","volume":"70","author":"Bokov","year":"2016","journal-title":"Comput Biol Med"},{"key":"10.1016\/j.resinv.2018.05.004_bib29","doi-asserted-by":"crossref","first-page":"353","DOI":"10.2332\/allergolint.12-RAI-0449","article-title":"Lung sounds in bronchial asthma","volume":"61","author":"Nagasaka","year":"2012","journal-title":"Allergol Int"},{"key":"10.1016\/j.resinv.2018.05.004_bib30","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1002\/ppul.23310","article-title":"Relationship between computerized wheeze detection and lung function parameters in young infants","volume":"51","author":"Fischer","year":"2016","journal-title":"Ped Pulmonol"}],"container-title":["Respiratory Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212534518301060?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212534518301060?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,5,19]],"date-time":"2020-05-19T17:32:17Z","timestamp":1589909537000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2212534518301060"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["S2212534518301060"],"URL":"https:\/\/doi.org\/10.1016\/j.resinv.2018.05.004","relation":{},"ISSN":["2212-5345"],"issn-type":[{"type":"print","value":"2212-5345"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Changes in the breath sound spectrum with bronchodilation in children with asthma","name":"articletitle","label":"Article Title"},{"value":"Respiratory Investigation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.resinv.2018.05.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}